Search Result

Search Results for " syk "

Targets

Syk Others Tyrosine Kinases Syk PKC BTK

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T4391	Syk Inhibitor II dihydrochloride	Syk Inhibitor II (hydrochloride)	Others , Tyrosine Kinases , Syk , PKC , BTK
	Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet fun...		Others , Tyrosine Kinases , Syk , PKC , BTK
T13045	Syk-IN-3		Syk
	Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.		Syk
T4348	Syk Inhibitor II		5-HT Receptor , Syk
	Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).		5-HT Receptor , Syk
T9543	Syk Inhibitor II hydrochloride		Others
	The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of...		Others
T24843	Syk-IN-1	SykIN11,Syk-IN-11,Syk IN 11,Syk inhibitor-11,Syk inhibitor 11,Syk-inhibitor-11
	Syk-IN-11 is a selective Syk inhibitor.
T37077	Syk-IN-4
	Syk-IN-4 is a potent, selective, and orally bioavailable inhibitor of SYK, demonstrating an IC50 of 0.31 nM. It targets SYK, which has been identified as a potential therapeutic target for autoimmunity and hematological ...
T4263	BAY 61-3606	Syk inhibitor IV	Apoptosis , Syk
	BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.		Apoptosis , Syk
T40976	Syk Kinase Peptide Substrate
	Syk Kinase Peptide Substrate is a Syk kinase peptide substrate.
T70931	SYK-IN-II
	SYK-IN-II is an inhibitor of the spleen tyrosine kinase (STK).
T62691	Syk Inhibitor II dihydrochloride dihydrate
	Syk Inhibitor II dihydrochloride dihydrate is a highly selective, potent, ATP-competitive Syk inhibitor (IC50: 41 nM). Syk Inhibitor II dihydrochloride dihydrate exhibits anti-allergic effects.
T78943	Syk-IN-7		Syk
	Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].		Syk
T70930	GSK SYK inhibitor
	The immunoregulator spleen tyrosine kinase (SYK) is upregulated in cutaneous lupus erythematosus (CLE). This double-blind, multicentre, Phase Ib study evaluated the safety, tolerability, pharmacokinetics, pharmacodynamic...
T79443	Syk-IN-8		Syk
	Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells. It specifically inhibits PLCγ2 phosphorylation and is applicable for blood cance...		Syk
T63086	SYK/JAK-IN-1
	SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.
T28281	OXSI-2	OXSI 2,Syk Inhibitor	Syk
	OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated events in platelets.		Syk
T76083	Syk Kinase Peptide Substrate, Biotin labeled
	The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.
T16776	RO9021		Syk
	RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).		Syk
T39437	Cevidoplenib dimesylate		Syk
	Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.		Syk
T11824LL	Lanraplenib	GS-9876	Syk
	Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI ...		Syk
T6101	Entospletinib	GS-9973	Syk
	Entospletinib (GS-9973) (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.		Syk
T14331	Gusacitinib	ASN-002	JAK , Syk
	Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).		JAK , Syk
T6594	MNS		Syk , Src , p97
	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.		Syk , Src , p97
T6115	Fostamatinib	R788	FLT , Syk , Monoamine Transporter , Adenosine Receptor
	Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.		FLT , Syk , Monoamine Transporter , Adenosine Receptor
T3185	R112	(E)-Elafibranor	Syk
	R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.		Syk
T2487	Cerdulatinib	PRT2070,PRT062070	Tyrosine Kinases , JAK , Syk
	Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.		Tyrosine Kinases , JAK , Syk
T6174	R406	R-406 besylate	Apoptosis , FLT , Syk
	R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.		Apoptosis , FLT , Syk
T70929	Naldemedine tosylate	S-297995 tosylate
	Naldemedine tosylate (S-297995) is an orally active μ-opioid receptor antagonist (PAMORA) with high binding affinities (K_i = 0.34, 0.43, 0.94 nM) and potent antagonist activities (IC_50 = 25.57, 7.09, 16.1 nM) towards h...
T6957	PRT-060318	P142-76,PRT318,PRT-060318 2HCl	Syk
	PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.		Syk
T6776	BAY 61-3606 dihydrochloride	BAY 61-3606,BAY-61-3606 dihydrochloride	Apoptosis , Syk
	BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).		Apoptosis , Syk
T2467	R406 free base	R406 (free base)	Apoptosis , FLT , Syk
	R406 free base (R406 (free base)) is a potent Syk inhibitor.		Apoptosis , FLT , Syk
T0948	Adrenalone hydrochloride	Adrenalone HCl	Adrenergic Receptor
	Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a loc...		Adrenergic Receptor
T2696	PRT062607 hydrochloride	PRT062607 (P505-15, BIIB057) HCl,P505-15 Hydrochloride	MLK , Syk , Src
	PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk (IC50: 1 nM). It displays at least 80-fold selectivity for Syk over other kinases.		MLK , Syk , Src
T4209	TAK-659 hydrochloride	TAK-659	VEGFR , FLT , Tyrosine Kinases , JAK , Syk
	TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.		VEGFR , FLT , Tyrosine Kinases , JAK , Syk
T2605	Fostamatinib Disodium	Tamatinib Fosdium,R788(Disodium),R788 Disodium,R788 (Fostamatinib) Disodium	FLT , Syk
	Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.		FLT , Syk
T6104	Cerdulatinib hydrochloride	Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride	MLK , c-Fms , Tyrosine Kinases , Hippo pathway , JAK , Syk
	Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19...
T32088	Sovleplenib	HMPL 523,HMPL523,HMPL-523	Syk
	Sovleplenib (HMPL523) is an orally available, selective and potent inhibitor of the splenic tyrosine kinase SYK with an IC50 of 25 nM.Sovleplenib has antitumor activity and may be used in studies of immune thrombocytopen...		Syk
T22430	SRX3207		Others , PI3K , Syk
	SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.		Others , PI3K , Syk
T9789	Cevidoplenib dimesylate hydrochloride		Syk
	Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.		Syk
T2600	AG490	Zinc02557947,Tyrphostin AG 490,AG 490,AG-490,Tyrphostin B42	EGFR , JAK , STAT , Autophagy
	AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.		EGFR , JAK , STAT , Autophagy
T5524	Aurora kinase inhibitor-3	Aurora Kinase Inhibitor III	Aurora Kinase
	Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.		Aurora Kinase
T2045	JANEX-1	Jak3 inhibitor I,WHI-P131	JAK
	JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM); little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases.		JAK
T6277	Doramapimod	BIRB 796	Raf , p38 MAPK , Autophagy
	Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.		Raf , p38 MAPK , Autophagy
T32613	LCB 03-0110 dihydrochloride		Src
	LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and T...		Src
T9428	HM43239		FLT
	HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. HM43239 directly inhibits the k...		FLT
T3211	Midostaurin	N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251	Others , PKC
	PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...		Others , PKC
T11824L	Lanraplenib monosuccinate	GS-9876 monosuccinate	Syk
	Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally...		Syk
T24584	P505-15 Acetate	PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate	Tyrosinase
	P505-15 Acetate is a selective inhibitor of spleen tyrosine kinase that acts by suppressing leukocyte immune function and inflammation and leading to a reduction in arthritis score and attenuated histological damage.		Tyrosinase
T11824	Lanraplenib succinate	GS-9876 succinate	Syk
	Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active S...		Syk
T21062	TAK-659	TAK 659,TAK659
	TAK-659 is a spleen tyrosine kinase (SYK) inhibitor.
T16995	TAS05567		FLT , c-RET , JAK , Syk
	TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, JAK2, KDR, and RET with IC50s of 10 nM, 4.8 nM, 600 nM, and...		FLT , c-RET , JAK , Syk

Compounds

Syk Inhibitor II dihydrochloride

T4391

Synonym: Syk Inhibitor II (hydrochloride)

Target: Others, Tyrosine Kinases, Syk, PKC, BTK

Target: 5-HT Receptor, Syk

Syk Inhibitor II hydrochloride

Synonym: SykIN11,Syk-IN-11,Syk IN 11,Syk inhibitor-11,Syk inhibitor 11,Syk-inhibitor-11

Synonym: Syk inhibitor IV

Target: Apoptosis, Syk

Syk Kinase Peptide Substrate

Syk Inhibitor II dihydrochloride dihydrate

Synonym: OXSI 2,Syk Inhibitor

Target: Syk

Syk Kinase Peptide Substrate, Biotin labeled

Cevidoplenib dimesylate

Target: Syk, Src, p97

Fostamatinib

T6115

Synonym: R788

Target: FLT, Syk, Monoamine Transporter, Adenosine Receptor

R112

T3185

Synonym: (E)-Elafibranor

Target: Syk

Cerdulatinib

T2487

Synonym: PRT2070,PRT062070

Target: Tyrosine Kinases, JAK, Syk

R406

T6174

Synonym: R-406 besylate

Target: Apoptosis, FLT, Syk

Naldemedine tosylate

T70929

Synonym: S-297995 tosylate

Target:

PRT-060318

T6957

Synonym: P142-76,PRT318,PRT-060318 2HCl

Target: Syk

BAY 61-3606 dihydrochloride

T6776

Synonym: BAY 61-3606,BAY-61-3606 dihydrochloride

Target: Apoptosis, Syk

R406 free base

T2467

Synonym: R406 (free base)

Target: Apoptosis, FLT, Syk

Adrenalone hydrochloride

T0948

Synonym: Adrenalone HCl

Target: Adrenergic Receptor

PRT062607 hydrochloride

T2696

Synonym: PRT062607 (P505-15, BIIB057) HCl,P505-15 Hydrochloride

Target: MLK, Syk, Src

TAK-659 hydrochloride

T4209

Synonym: TAK-659

Target: VEGFR, FLT, Tyrosine Kinases, JAK, Syk

Fostamatinib Disodium

T2605

Synonym: Tamatinib Fosdium,R788(Disodium),R788 Disodium,R788 (Fostamatinib) Disodium

Target: FLT, Syk

Cerdulatinib hydrochloride

T6104

Synonym: Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride

Target: MLK, c-Fms, Tyrosine Kinases, Hippo pathway, JAK, Syk

Sovleplenib

T32088

Synonym: HMPL 523,HMPL523,HMPL-523

Target: Others, PI3K, Syk

Cevidoplenib dimesylate hydrochloride

Synonym: Zinc02557947,Tyrphostin AG 490,AG 490,AG-490,Tyrphostin B42

Target: EGFR, JAK, STAT, Autophagy

Aurora kinase inhibitor-3

T5524

Synonym: Aurora Kinase Inhibitor III

Target: Aurora Kinase

JANEX-1

T2045

Synonym: Jak3 inhibitor I,WHI-P131

Target: Raf, p38 MAPK, Autophagy

LCB 03-0110 dihydrochloride

Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251

Target: Others, PKC

Lanraplenib monosuccinate

T11824L

Synonym: GS-9876 monosuccinate

Target: Syk

P505-15 Acetate

T24584

Synonym: PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate

Target: Tyrosinase

Lanraplenib succinate

T11824

Synonym: GS-9876 succinate

Target: Syk

TAK-659

T21062

Synonym: TAK 659,TAK659

Target: FLT, c-RET, JAK, Syk

Cat No.	Product Name	Synonyms	Targets
TN1644	Flavanomarein		Others
	Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...		Others
T0610	Piceatannol	trans-Piceatannol,Astringenin	Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy
	Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is...
TN7075	Linocinnamarin	3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester	Phospholipase , Syk
	Linocinnamarin (3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester) is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen-stimulated degranulation by LN is mainly due to inactivati...		Phospholipase , Syk
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
TN6667	Spinacetin
	Spinacetin has anti-inflammatory effects, it weakly inhibited nitric oxide production and reduced prostaglandin E2 levels to different extents. It shows the activities in preventing inflammatory processes, which might be...

Natural Products

Synonym: trans-Piceatannol,Astringenin

Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy

Linocinnamarin

TN7075

Synonym: 3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester

Target: Phospholipase, Syk

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPY-03623	NKp80/KLRF1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	NKp80, also known as KLRF1, is an activating homodimeric C-type lectin-like receptor that is expressed on nearly all-natural killer cells and stimulates their cytotoxicity and cytokine release. NKp80 stimulates cytotoxic...
TMPH-00544	Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO)	EBV	E. coli
	Isoform LMP2A maintains EBV latent infection of B-lymphocyte, by preventing lytic reactivation of the virus in response to surface immunoglobulin (sIg) cross-linking. Acts like a dominant negative inhibitor of the sIg-as...
TMPH-00323	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-02441	IL-15 Protein, Rhesus macaque, Recombinant (His)	Rhesus	Yeast
	Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA. In neutrophils, stimula...
TMPH-00320	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	Yeast
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00322	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	Yeast
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPJ-00252	SIRP beta 1 Protein, Human, Recombinant (His)	Human	Human Cells
	Signal-regulatory protein beta-1 (SIRPB1, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glyco...
TMPH-00321	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPY-02131	Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)	Human	E. coli
	The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im...
TMPK-00252	SIRP beta 1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like s...
TMPK-00253	SIRP beta 1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like s...
TMPY-03440	Sts1 Protein, Human, Recombinant (His)	Human	E. coli
	UBASH3B contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. UBASH3B was found to inhibit endocytosis of ep...
TMPH-01342	Filamin-A Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplas...
TMPY-02357	CLEC-2 Protein, Human, Recombinant (His)	Human	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPJ-00534	HFcgR4 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso...
TMPY-03173	Dectin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	C-type lectin domain family 4 member N (CLEC4N), also known as Dectin-2, is a C-type lectin expressed by dendritic cells (DCs) and macrophages. Members of the C-type lectin domain (CTLD) superfamily are metazoan proteins...
TMPY-01202	Dectin-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	C-type lectin domain family 4 member N (CLEC4N), also known as Dectin-2, is a C-type lectin expressed by dendritic cells (DCs) and macrophages. Members of the C-type lectin domain (CTLD) superfamily are metazoan proteins...
TMPH-01044	CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPH-01045	CEACAM1 Protein, Human, Recombinant	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPH-01692	MAPK3 Protein, Human, Recombinant (His)	Human	E. coli
	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
TMPH-00297	S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)	Bovine	E. coli
	S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal act...
TMPH-02962	Lyn Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors an...