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Results for "ada" in TargetMol Product Catalog
  • Inhibitor Products
    159
    TargetMol | Activity
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    37
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ADA
T2237326239-55-4
ADA (N-(2-Acetamido)-2-Iminodiacetic acid) is a biological buffer which can serve as a chelator[1][2].
  • $40
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ADA sodium salt
T665627415-22-7
ADA sodium salt is a useful organic compound for research related to life sciences. The catalog number is T66562 and the CAS number is 7415-22-7.
    7-10 days
    Inquiry
    ADA-07
    T697272252153-94-7
    ADA-07 is a TOPK inhibitor which interacts with TOPK at the ATP-binding pocket and inhibits its kinase activity, thereby suppressing SUV-induced phosphorylation of ERK1/2, p38, and JNKs, and subsequently inhibiting AP-1 activity.
    • $1,520
    6-8 weeks
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    Adalimumab
    T9901331731-18-1
    Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
    • $213
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    TargetMol | Citations Cited
    Adagrasib
    T83692326521-71-3
    Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.
    • $59
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    1-IODOADAMANTANE
    T7034768-93-4
    1-IODOADAMANTANE (1-Adamantyl Iodide) is employed in the free-radical carbonylation reactions with alkenes.
    • $80
    In Stock
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    Adamantane
    T5658281-23-2
    The adamantane moiety is the structural backbone of numerous compounds and the physicochemical and biological properties of organic polyhedral compounds with practical application in the pharmaceutical industry.
    • $39
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    N-(1-Adamantyl)acetamide
    T0645880-52-4
    N-(1-Adamantyl)acetamide is used as intermediates for synthesis of amantadine hydrochloride.
    • $50
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    2-Adamantanol
    TWO2771700-57-2
    2-Adamantanol (2-Hydroxyadamantane) was used to synthesize antiallergic drug Mizolastine.
    • $29
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    Lefradafiban
    T27808149503-79-7In house
    Lefradafiban(BIBU-104) is an oral platelet glycoprotein IIb/IIIa receptor antagonist for the study of angina pectoris and acute coronary syndromes.
    • $342
    In Stock
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    Adafosbuvir PM
    T677871613589-04-0In house
    Adafosbuvir PM (AL-335 PM) is a small molecule NS5B inhibitor that can be used to study chronic hepatitis C.
    • $260
    In Stock
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    Adatanserin
    T23631127266-56-2In house
    Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist with potential neuroprotective activity for the study of coke oven and depression.
    • $293 TargetMol
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    Adamantanine
    T2001342381-05-5
    Adamantanine (NSC-145160) is an amino acid transport inhibitor.
    • $57
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    Adatanserin hydrochloride
    T29645144966-96-1In house
    Adatanserin hydrochloride (WY50324 hydrochloride) is a novel 5-HT(1A)/5-HT(2) receptor ligand with potential neuroprotective effects and inhibition of ischemic efflux of endogenous amino acids, which can be used in the study of depression and anxiety disorders.
    • $195 TargetMol
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    N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide
    T8502314030-54-1
    N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide inhibiting the entry of Ebola virus in host cells by binding to the surface glycoprotein, the compound inhibited the Ebola virus with EC50 of 3.9 μM.
    • $133
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    Azodicarbonamide
    T77793123-77-3
    Azodicarbonamide is the first nucleocapsid inhibitor known to inhibit HIV-1 and various retroviruses by targeting the nucleocapsid CCHC domains. In a standard cellular antiviral assay, the compound inhibited HIV-1RF-induced CEM-SS cytopathy with an EC50 value of 38 µM.
      Inquiry
      Luvadaxistat
      T388631425511-32-5
      Luvadaxistat (TAK-831) is an orally active, potent and highly selective inhibitor of D-amino acid oxidase (DAAO) with an IC50 value of 14 nM for the oxidative deamination of D-serine.Luvadaxistat is used in the study of schizophrenia and cognitive disorders.
      • $88 TargetMol
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      Omadacycline
      T5189389139-89-3
      Omadacycline (Amadacycline), a new tetracycline antibiotic, can inhibit the 30s subunit of bacterial ribosome.
      • $51
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      TargetMol | Citations Cited
      Adavosertib
      T2077955365-80-7
      Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.
      • $40
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      Adapalene
      T1093106685-40-9
      Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.
      • $42
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      TargetMol | Citations Cited
      Upadacitinib
      T75031310726-60-3
      Upadacitinib (ABT-494) (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM.
      • $39
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      Oditrasertib
      T697262252271-93-3
      Oditrasertib (DNL-788) is a potent RIPKl inhibitor with an IC50 value of less than 100 nM.Oditrasertib can be used for the study of immune and neurological disorders such as multiple sclerosis and Alzheimer's disease.
      • $139
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      Ladanetin-6-O-β-(6′′-O-acetyl)glucoside
      T819561256959-27-9
      Ladanetin-6-O-β-(6′′-O-acetyl)glucoside, a flavonoid extracted from Dracocephalum tanguticum whole plants, exhibits antioxidant properties and cardioprotective effects, mitigating Doxorubicin-induced toxicity in H9c2 cells [1].
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      Genkwadaphnin
      T8232655073-32-0
      Genkwadaphnin, a daphnane diterpenoid, targets importin-β1, reducing the nuclear accumulation of CRPC drivers and suppressing downstream oncogenic signaling. Demonstrating potent anti-tumor effects, it inhibits castration-resistant prostate cancer (CRPC) in vivo in mice [1].
      • Inquiry Price
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      Omadacycline tosylate
      T207531075240-43-5
      Omadacycline tosylate is a new tetracycline.
      • $956
      7-10 days
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      3alpha-dihydrocadambine
      TN299054483-84-0
      3alpha-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats.
      • $2,178
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      Yadanzioside K
      TN5268101559-98-2
      Yadanzioside K is a natural product from Brucea javanica.
      • $820
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      Adaptaquin
      T22022385786-48-1
      Adaptaquin is an inhibitor of the hypoxia-inducing factor prolyl hydroxylase (HIF-PH) [1] [2].
      • $47
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      cis-ent-Tadalafil
      T78216171596-28-4
      cis-ent-Tadalafil (cis-ent-IC-351) is a potent and selective PDE5 inhibitor that lowers blood pressure. cis-ent-Tadalafil is a potent and selective PDE5 inhibitor that reduces blood pressure.
      • $347
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      Adamtsostatin 18
      T83171929554-95-0
      Adamtsostatin 18, an anti-angiogenic peptide derived from proteins with type I thrombospondin motifs, suppresses cell migration and proliferation [1].
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      Kihadanin B
      TN439073793-68-7
      Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
      • $2,340
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      Fradafiban
      T11322148396-36-5
      Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
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      ent-Tadalafil
      T11206629652-72-8
      ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).
      • $778
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      C2 Adamantanyl Galactosylceramide (d18:1/2:0)
      T37440574738-16-2
      C2 Adamantanyl Galactosylceramide (d18:1/2:0) (AdaGalCer) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively.
      • $777
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      Cadambine
      TN609554422-49-0
      Cadambine is a natural product for research related to life sciences. The catalog number is TN6095 and the CAS number is 54422-49-0.
      • $2,178
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      cis-Tadalafil
      T20024171596-27-3
      cis-Tadalafil (cis-IC-351) is a potent PDE5 inhibitor with an IC50 value of 0.09 μM that can be used to study arterial hypertension.
      • $293
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      Kihadanin A
      TN4389125276-62-2
      Kihadanin A is a natural product from Phellodendron amurense.
      • $670
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      Cyclo-cadagac
      T31133143084-70-2
      Cyclo-cadagac is a cyclic heptapeptide.
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      Nortadalafil
      T6147171596-36-4
      Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
      • $31
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      Yadanzioside M
      TN5269101559-99-3
      Yadanzioside M has antitumor activity.
      • $820
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      Yadanzioside L
      TN232199132-97-5
      Yadanzioside L shows strong antiviral activity.
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      Iladatuzumab
      T820781906205-76-2
      Iladatuzumab (MCDS0593A), a humanized IgG1 monoclonal antibody targeting CD79B, serves as a precursor for the synthesis of antibody-drug conjugates (ADCs), such as Iladatuzumab vedotin (DCDS0780A), with potential applications in B-cell non-Hodgkin lymphoma (B-NHL) research [1] [2].
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      Adamtsostatin 4
      T83170929554-73-4
      Adamtsostatin 4, an anti-angiogenic peptide, is utilized in research related to angiogenesis inhibition [1].
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      Adam-20-S
      T831722413880-52-9
      Adam-20-S is a potent inhibitor of glucosinolate sulfatase, exhibiting an IC50 of 9.04 μg/mL. This compound disrupts glucosinolate metabolism, enhancing the production of toxic isothiocyanates in P. xylostella [1].
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      N-Ethyl tadalafil
      T199981609405-34-6
      N-Ethyl tadalafil is a compound of bioactive chemicals.
      • $30
      7-10 days
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      C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
      T38011261155-87-7
      C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal C2BBe1 cells.
      • $661
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      Amino Tadalafil
      T7542385769-84-6
      Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.
      • $35
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      2-Adamantanone
      T5659700-58-3
      2-Adamantanone is a bioactive chemical.
      • $29
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      Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside
      T824631427191-48-7
      Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside (MFLNH I) (compound 5), which exhibits stomach pain suppression properties [1], is extracted from the seed kernel of the Thai medicinal plant Entada rheedei.
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      Yadanzioside P
      TN527079439-84-2
      Yadanzioside P has antileukemic and antitumor activities.
      • $740
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