fungi

Multifungin (Bromochlorosalicylanilide) is an antifungal agent used in studies of oral candidiasis, reducing fungal populations in stored corn and preventing zearalenone formation and accumulation.

Rezafungin (SP-3025) is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.

Abafungin (Bay w 6341) is an antifungal agent with a broad-spectrum.

Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7 9 inhibitor and ameliorates renal fibrosis by inhibiting H3K4 methylation.

Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species.

Anidulafungin (Ecalta) (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity.

Micafungin sodium (FK 463) is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity.

Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pathogenic filamentous and dimorphic fungi such as Penicillium spp, Dermatophilus spp and Fusarium spp.

Arcyriaflavin A is a metabolite obtained from the fungi, Nocardiopsis sp.

3,4-Dimethoxybenzyl alcohol is a secondary metabolite of lignin-degrading fungi and is commonly used as a non-phenolic substrate to measure ligninolytic activity.Veratryl alcohol protects lignin peroxidase (LiP) from inactivation by H2O2 and prevents accumulation of LiP III compounds[3].

Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essential component of fungal cell membranes. This is vital in the cell membrane structure of the fungus. Its inhibition leads to cell lysis. The disruption in production of ergosterol disrupts the cell membrane and causes holes to appear. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out.

Chitin is a large, structural polysaccharide found in the cell walls of fungi, the exoskeletons of insects, and certain hard structures in fish and invertebrates.

Glycogen, Mussel is a glycolytic intermediate and high-energy phosphate that ACTS as a form of energy storage for humans, animals, fungi and bacteria.

Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.

Fluconazole (UK-49858) is a triazole antifungal agent used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.

Chloroxylenol (PCMX) (4-chloro-3, 5-dimethylphenol), a broad spectrum antimicrobial chemical compound, is used to control virus, bacteria, fungi, and algae. It is used in households and hospitals for sanitation and disinfection.

Phenazine-1-carboxylic acid shows strong antifungal activity against all phytopathogenic fungi, inhibiting the fungal growth by about 90-100%. Phenazine-1-carboxylic acid could be used to compete with other phytopathogenic fungi that attack grapevine

meso-Erythritol (Phycitol) is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.

Berberine hydrogen sulphate (Umbellatine Sulfate) , an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.

Gibberellic acid (GA3) is a hormone found in plants and fungi.

2,6-Dimethoxybenzoic acid is an o-methoxybenzoic acid and its derivatives that inhibit fungi and bacteria.

4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts of purine adducts.

Itaconic acid is a precursor for the synthesis of polymers, chemicals, and fuels, and has anti-inflammatory activity.Itaconic acid can be synthesized by fungi. It is also a macrophage-specific metabolite. It mediates crosstalk between macrophage metabolism and peritoneal tumors.

Laccase (Denilite IIS) is a polycopper oxidase (MCOs) widely found in microorganisms, plants, and fungi with antimicrobial activity and cytotoxicity that can be used in the study of cancer.Laccase promotes oxidative coupling of mono-lignin in lignin formation.

Tolnaftate (NP-27) is a synthetic antifungal agent used to treat skin infections caused by fungi.

Itaconic acid is a precursor for the synthesis of polymers, chemicals, and fuels, and has anti-inflammatory activity.Itaconic acid can be synthesized by fungi. It is also a macrophage-specific metabolite. It mediates crosstalk between macrophage metabolism and peritoneal tumors.

4-Hydroxy-6-methylcoumarin (4-HMC) is a naturally occurring phenolic compound, a derivative of coumarin, found in a variety of plants, fungi, and bacteria. It has anti-inflammatory and anti-tumor activity.4-HMC is used as a flavoring agent, preservative and antioxidant in the food industry.

Nonanal is a growth factor for wood-rotting fungi. Nonanal is a potential attractant for the pine shoot beetle.

WAY-324208 shows antifungal properties against S. dermatitidis (skin-infecting fungi), with activity against other fungi to be explored.

5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA. 5-Aminouridine inhibits the growth of tumors, viruses, and fungi.

Propiosyringone is from the degradation of Eucalyptus globulus wood by wood-rotting fungi.

Loflucarban (Fluonilid) is an antimycotic compoud.

Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent effective against various microorganisms, including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi (Pneumocystis jirovecii). It is a potent and selective inhibitor of protein tyrosine phosphatases and phosphatase of regenerating liver. Pentamidine dihydrochloride inhibits the parasite Leishmania infantum with an IC50 of 2.5 μM.

Hexadecane (n-Hexadecane) acts as a carbon source for fungi and is associated with biodegradation by anaerobic organisms.Hexadecane inhibited skin hyperkeratinization in guinea pig skin experiments.

(E,E)-Farnesol ((2E,6E)-Farnesol) is a sesquiterpene acyclic alcohol produced by bacteria, protozoa, fungi, plants, and animals. (E,E)-Farnesol promotes vasodilation.

Di-O-methylhonokiol (Honokiol dimethyl ether), a phenolic component of Magnolia grandiflora L, exhibits antimicrobial activity and significant antioxidant activity against Gram-positive and acid-resistant bacteria and fungi.

Dermaseptin acetate, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration[1].

Piperazinomycin is an antifungal antibiotic, showing inhibitory activity against fungi and yeasts, especially against Trichophyton.

Embeconazole (R 120758) is a triazole antifungal agent.Embeconazole has strong in vitro activity against clinically important fungi such as Candida, Aspergillus and Cryptococcus neoformans.

Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses related plant diseases. Additionally, Pyoluteorin induces apoptosis in human triple-negative breast cancer (MDA-MB-231) cells in vitro.

Kalafungin antimicrobial agent that is inhibitory in vitro against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria, and, to a lesser extent, gram-negative bacteria.

Enfumafungin, a triterpene glycoside extracted from Hormonema carpetanum fungus, acts as an antifungal by inhibiting (1,3)-beta-D-glucan synthase, crucial for fungal cell wall synthesis. It selectively targets yeasts and fungi, excluding Cryptococcus, without affecting Bacillus subtilis growth [1] [2].

Dactylfungins A is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.

Dactylfungins B is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.

Fumifungin is a useful organic compound for research related to life sciences. The catalog number is T126406 and the CAS number is 110231-33-9.

Icofungipen is an oral antifungals with active against Candida species.

Guanidylfungin A is a useful organic compound for research related to life sciences. The catalog number is T123899 and the CAS number is 94116-22-0.

Caspofungin-d4-Dicarboxylic acid is a deuterated compound of Caspofungin-Dicarboxylic acid. Caspofungin-Dicarboxylic acid has a CAS number of 162808-62-0.