TN1365 |
Albaspidin AP
|
59092-91-0
|
98%
|
|
Albaspidin-AP, -PP, -PB inhibit Fatty acid synthase (FAS) with IC50 values ranging from 23.1+/-1.4 to 71.7+/-3.9 microM, they could be considered to be a promisi...
|
T11266L |
FAS-IN-1 Tosylate
|
T11266L
|
98%
|
|
FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.
|
T27307L |
Fasnall HCl
|
|
98%
|
|
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall HCl also shows potent anti-tumor activity in the MMTV-Neu model ...
|
TN2083 |
Pinostrobin chalcone
|
18956-15-5
|
98%
|
|
Pinostrobin chalcone is a potent inhibitor of triglyceride accumulation, it can inhibit adipogenesis in 3T3-L1 cells, it may have anti-obesity effects through th...
|
TN4094 |
Gallocatechin gallate
|
5127-64-0
|
98%
|
|
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation throu...
|
T4S1421 |
Praeruptorin B
|
73069-28-0
|
98%
|
|
Praeruptorin D is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via t...
|
TN1751 |
Hydroxycitric acid
|
6205-14-7
|
98%
|
|
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to ac...
|
T3S1701 |
Dihydrocurcumin
|
76474-56-1
|
98%
|
|
Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and pr...
|
T21831 |
UCM05
|
1094451-90-7
|
98%
|
|
UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase ( FASN ) shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resist...
|
TN2535 |
1-Hydroxy-2-oxopomolic acid
|
217466-37-0
|
98%
|
|
1β-Hydroxy-2-oxopomolic acid inhibits adipocyte differentiation through downregulation of various adipocytokines by blocking PPARγ and C/EBPα expression.
|
T14570 |
BI 99179
|
1291779-76-4
|
98%
|
|
BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and cent...
|
T11267 |
FASN-IN-1
|
1808260-84-5
|
98%
|
|
FASN-IN-1 is a fatty acid synthase (FASN) inhibitor .
|
T36841 |
IPI-9119
|
1346564-56-4
|
98%
|
|
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).
|
T27307 |
Fasnall
|
929978-58-5
|
98%
|
|
Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) br...
|
T21724L |
Fas C-Terminal Tripeptide Acetate
|
T21724L
|
|
|
Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.
|
T14298 |
Rimiducid
|
195514-63-7
|
|
|
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affin...
|
T7947 |
FT113
|
1630808-89-7
|
97.68%
|
|
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
|
TN1803 |
Isoscoparin
|
20013-23-4
|
97.95%
|
|
Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be used in stuides about the prevention and tre...
|
T5S0246 |
Pseudoprotodioscin
|
102115-79-7
|
98%
|
|
1. Pseudoprotodioscin has moderate cytotoxicity.
|
TJS0387 |
Desoxyrhaponticin
|
30197-14-9
|
98%
|
|
1. Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this com...
|