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Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.
Cat. No. Product name CAS No. Purity Chemical Structure
TQ0245 Sapacitabine 151823-14-2 98%
Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T5539 GS-443902 1355149-45-9 98%
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
T15378 Gemcitabine elaidate 210829-30-4 98%
Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential ...
TQ0006 Ethynylcytidine 180300-43-0 98%
Ethynylcytidine is a nucleoside antimetabolite.
T36944 Ara-G 38819-10-2 98%
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
T9726 2’-OMe-Guanosine 2140-71-8 98%
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
T38958 DMT-2′Fluoro-dU Phosphoramidite 146954-75-8 98%
DMT-2′Fluoro-dU Phosphoramidite can be used to modify nucleosides.
T9727 2'-Fluoro-2'-Deoxyadenosine 64183-27-3 98%
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
T38238 2'-Deoxy-2'-fluorocytidine 10212-20-1 98%
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
TNU0839 1,4-Dideoxy-1,4-epithio-D-ribitol 190315-43-6 98%
1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of ant...
T20102 8-Azahypoxanthine 2683-90-1 98%
8-Azahypoxanthine is an antimalarial. It inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase.
T36866 3-Deazauridine 23205-42-7 98%
3-Deazauridine is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate sy...
T19083 1-Methylinosine 2140-73-0 98%
1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
TNU0436 2-Thiocytidine 13239-97-9 98%
2-Thiocytidine is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and has a broad spectrum of antitumor activity.2-Thiocyt...
T14329 Ascamycin 91432-48-3 98%
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and...
T38237 2′-O-Methylcytidine 2140-72-9 98%
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
T38236 2′-Deoxy-2′-fluoroguanosine 78842-13-4 98%
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains....
T36971 5-Ethynyluridine 69075-42-9 98%
5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. ...
T4061 LY2334737 892128-60-8 98%
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
T7319 7-Methylguanosine 20244-86-4 98%
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).
Sapacitabine
TQ0245
Sapacitabine is a nucleoside analog prodrug with antitumor activity.
GS-443902
T5539
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
Gemcitabine elaidate
T15378
Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential ...
Ethynylcytidine
TQ0006
Ethynylcytidine is a nucleoside antimetabolite.
Ara-G
T36944
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
2’-OMe-Guanosine
T9726
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
DMT-2′Fluoro-dU Phosphoramidite
T38958
DMT-2′Fluoro-dU Phosphoramidite can be used to modify nucleosides.
2'-Fluoro-2'-Deoxyadenosine
T9727
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
2'-Deoxy-2'-fluorocytidine
T38238
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
1,4-Dideoxy-1,4-epithio-D-ribitol
TNU0839
1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of ant...
8-Azahypoxanthine
T20102
8-Azahypoxanthine is an antimalarial. It inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase.
3-Deazauridine
T36866
3-Deazauridine is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate sy...
1-Methylinosine
T19083
1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
2-Thiocytidine
TNU0436
2-Thiocytidine is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and has a broad spectrum of antitumor activity.2-Thiocyt...
Ascamycin
T14329
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and...
2′-O-Methylcytidine
T38237
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
2′-Deoxy-2′-fluoroguanosine
T38236
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains....
5-Ethynyluridine
T36971
5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. ...
LY2334737
T4061
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
7-Methylguanosine
T7319
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).
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