T8957 |
CRT0066101
|
956121-30-5
|
98%
|
|
CRT0066101 is an inhibitor of PKD.
|
T1606 |
Fasudil
|
103745-39-7
|
98%
|
|
Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
|
T16931 |
SRPKIN-1
|
2089226-94-6
|
98%
|
|
SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).
|
T11666 |
IPR-803
|
892243-35-5
|
98%
|
|
IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM....
|
T15781 |
LP-935509
|
1454555-29-3
|
98%
|
|
LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is also an effective inhibitor of BIKE (I...
|
T4058 |
R-IMPP
|
2133832-83-2
|
100%
|
|
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted ...
|
T5456 |
WNK-IN-11
|
2123489-30-3
|
100%
|
|
WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)
|
T10547 |
BioE-1115
|
1268863-35-9
|
97.38%
|
|
BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).
|
T7017 |
WNK463
|
2012607-27-9
|
98%
|
|
WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).
|
T19763 |
Cetraxate hydrochloride
|
27724-96-5
|
98.23%
|
|
Cetraxate HCl is an oral gastrointestinal medication. It has a cytoprotective effect.
|
T9256 |
N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine
|
1071135-06-2
|
98.35%
|
|
N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein...
|
T13257 |
Upamostat
|
590368-25-5
|
98.8%
|
|
Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.
|
T27525 |
HA-1004
|
91742-10-8
|
99.03%
|
|
HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.
|
T8676 |
FOY 251
|
71079-09-9
|
99.04%
|
|
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
|
T2153 |
1-NM-PP1
|
221244-14-0
|
99.2%
|
|
1 nM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
|
T1858 |
CID-797718
|
370586-05-3
|
99.25%
|
|
CID797718 is a protein kinase D1 (PKD1) inhibitor.
|
T5194 |
SPHINX31
|
1818389-84-2
|
99.3%
|
|
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
|
TN2082 |
Pinostrobin
|
480-37-5
|
99.35%
|
|
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting...
|
T0610 |
Piceatannol
|
10083-24-6
|
99.39%
|
|
Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activat...
|
T7444 |
6-(Dimethylamino)purine
|
938-55-6
|
99.49%
|
|
6-(Dimethylamino)purine is a serine threonine protein kinase and CDK inhibitor
|