Serine/threonin kinase

Serine threonine kinase belongs to protein kinase, which can phosphorylate the OH group of serine or threonine residues. Serine threonine kinases contain Rho kinase, Aurora kinase, AMP kinase, RAF kinase, Polo like kinase, PIM kinase, ATM kinase and other kinases. The cAMP/cGMP, Ca2+/calmodulin and diacylglycerol and multiple chenmical signals can regulate the activity of serine threonine kinases.

Cat. No.	Product name	CAS No.	Purity
T8957	CRT0066101	956121-30-5	98%
T8957	CRT0066101 is an inhibitor of PKD.
T1606	Fasudil	103745-39-7	98%
T1606	Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T16931	SRPKIN-1	2089226-94-6	98%
T16931	SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).
T11666	IPR-803	892243-35-5	98%
T11666	IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM....
T15781	LP-935509	1454555-29-3	98%
T15781	LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is also an effective inhibitor of BIKE (I...
T4058	R-IMPP	2133832-83-2	100%
T4058	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted ...
T5456	WNK-IN-11	2123489-30-3	100%
T5456	WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)
T10547	BioE-1115	1268863-35-9	97.38%
T10547	BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).
T7017	WNK463	2012607-27-9	98%
T7017	WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).
T19763	Cetraxate hydrochloride	27724-96-5	98.23%
T19763	Cetraxate HCl is an oral gastrointestinal medication. It has a cytoprotective effect.
T9256	N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine	1071135-06-2	98.35%
T9256	N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein...
T13257	Upamostat	590368-25-5	98.8%
T13257	Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.
T27525	HA-1004	91742-10-8	99.03%
T27525	HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.
T8676	FOY 251	71079-09-9	99.04%
T8676	FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
T2153	1-NM-PP1	221244-14-0	99.2%
T2153	1 nM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
T1858	CID-797718	370586-05-3	99.25%
T1858	CID797718 is a protein kinase D1 (PKD1) inhibitor.
T5194	SPHINX31	1818389-84-2	99.3%
T5194	SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
TN2082	Pinostrobin	480-37-5	99.35%
TN2082	Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting...
T0610	Piceatannol	10083-24-6	99.39%
T0610	Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activat...
T7444	6-(Dimethylamino)purine	938-55-6	99.49%
T7444	6-(Dimethylamino)purine is a serine threonine protein kinase and CDK inhibitor