Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

Cat No.	product name
L1120	AMPK-Targeted Compound Library	64 well-chosen unique AMPK-targeted small molecules；	64 compounds
L4100	TGF-beta/Smad Compound Library	A unique collection of 180 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;	180 compounds
L3900	DNA Damage & Repair Compound Library	A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);	937 compounds
L1310	Cytoskeletal Signaling Pathway Compound Library	A unique collection of 590 cytoskeleton-related compounds, can be used for HTS and HCS；	590 compounds
L4800	Angiogenesis related Compound Library	A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);	1370 compounds
L2700	Adrenergic Receptor-Targeted Compound Library	A unique collection of 219 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;	219 compounds
L8500	HIF-1 Signaling Pathway Compound Library	A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；	1352 compounds
L2610	Neurotransmitter Receptor Compound Library	A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；	1513 compounds
L4300	Wnt/Hedgehog/Notch Compound Library	A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;	240 compounds
L1580	GPCR Compound Library Plus	Well-chosen 338 GPCR targeting compounds with unique structures;	338 compounds
L3700	JAK-STAT Compound Library	A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening;	256 compounds
L9100	Phosphatase Inhibitor Library	A collection of 80 phosphatase inhibitors with known activity;	80 compounds
L2000	Inhibitor Library	A unique collection of 7619 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;	7619 compounds
L8100	Cell Cycle Compound Library	A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);	695 compounds
L8600	Ubiquitination Compound Library	A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening；	214 compounds
L7300	Potassium Channel Blocker Library	A unique collection of 160 potassium channel blockers and agonists for high throughput and high content screening;	160 compounds
L7200	Calcium Antagonist Library	A unique collection of 143 calcium channel blockers and agonists for high throughput and high content screening;	143 compounds
L1110	Microtubule-Targeted Compound Library	A unique collection of 80 microtubule-targeted compounds can be used in HTS and HCS;	80 compounds
L1600	Kinase Inhibitor Library	A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;	2230 compounds
L9000	Apoptosis Compound Library	A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;	1796 compounds
L1100	Protease Inhibitor Library	A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;	344 compounds
L9700	Endoplasmic Reticulum Stress Compound Library	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);	193 compounds
L3600	Cytokine Inhibitor Library	A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;	613 compounds
L9420	Exosome Compound Library	54 exosome-related compounds that can be used for high-throughput and high-content screening.	54 compounds
L1400	MAPK Inhibitor Library	A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;	367 compounds
L1200	Epigenetics Compound Library	Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;	960 compounds
L1510	Nuclear Receptor Compound Library	A unique collection of 420 nuclear receptor signaling targeted compounds for high throughput and high content screening;	420 compounds
L3200	Autophagy Compound Library	A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;	1248 compounds
L3510	Methylation Compound Library	131 methylation-related compounds that can be used for high-throughput and high-content screening.	131 compounds
L2300	Ion Channel Inhibitor Library	A unique collection of 946 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;	946 compounds
L8700	Ferroptosis Compound Library	A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；	800 compounds
L2800	Serotonin Receptor-Targeted Compound Library	A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening;	275 compounds
L5300	Mitochondria-Targeted Compound Library	A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;	447 compounds
L3800	NF-κB Signaling Compound Library	A unique collection of 560 compounds targeting NF-κB signaling for high throughput screening and high content screening;	560 compounds
L2600	Neuronal Signaling Compound Library	A unique collection of 2011 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;	2011 compounds
L2200	Tyrosine Kinase Inhibitor Library	A unique collection of 746 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;	746 compounds
L1500	GPCR Compound Library	A unique collection of 1633 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;	1633 compounds
L3300	Histamine & Melatonin Receptor-Targeted Compound Library	A unique collection of 155 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;	155 compounds
L7400	Sodium Channel Blocker Library	A unique collection of 128 sodium channel blockers and agonists for high throughput and high content screening;	128 compounds
L7600	Chemokine Inhibitor Library	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;	59 compounds
L1300	PI3K-AKT-mTOR Compound Library	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;	425 compounds