17a-hydroxy-19-norprogesterone

6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilized for research in the fields of chemistry and life sciences.

Enmein, 13-deoxy-19-hydroxy-, (19R)- is an Enmein-type diterpene derivative and can be used in the preparation of antitumor drugs.

17-Hydroxy sprengerinin C is a glycoside compound isolated from rhizomes of Polygonatum sibiricum with stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increases the production of Bax.

19(R)-Hydroxylated prostaglandins (PGs) are present at µg/ml concentrations in the semen of some mammalian species, notably primates, with the majority being from the PGE series and featuring a 15(S),19(R) hydroxyl stereochemistry. These compounds are also observed in marsupials' seminal plasma, where F-type 1 and 2-series compounds are predominant. The 15(R)-hydroxy epimer represents the inverse or unnatural isomer at C-15 for these 19-hydroxylated PGs. Although the biological function of 19(R)-hydroxylated PGs remains unclear, 19(R)-hydroxylation in the F-series leads to a notable reduction in receptor-mediated biological activity in certain assays.

17-Hydroxyheptadecanoic acid, a hydroxylated fatty acid identified in aeolian particles from the Frioul Islands and the outer bark of E. globulus, serves in the synthesis of diverse macrocyclic lactones. [Matreya, LLC. Catalog No. 1760]

ent-9-Hydroxy-15-oxokauran-19-oic acid is a natural product for research related to life sciences. The catalog number is TN5577 and the CAS number is 77658-45-8.

ent-9-Hydroxy-15-oxo-16-kauren-19-oic acid is a natural product for research related to life sciences. The catalog number is TN3956 and the CAS number is 77658-39-0.

Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to be determined. 1.Serhan, C.N., Gotlinger, K., Hong, S., et al.Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienesJ. Immunol.176(3)1848-1859(2006) 2.Ariel, A., and Serhan, C.N.Resolvins and protectins in the termination program of acute inflammationTRENDS in Immunology28(4)176-183(2007) 3.Schwab, J.M., Chiang, N., Arita, M., et al.Resolvin E1 and protectin D1 activate inflammation-resolution programmesNature447(7146)869-874(2007)

(R)-Methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate is a useful organic compound for research related to life sciences. The catalog number is T66656 and the CAS number is 10538-59-7.

19(R)-hydroxy Prostaglandin E2 (19(R)-hydroxy PGE2), present in the semen of primates, including humans, acts as a potent smooth muscle relaxant and is a selective agonist for the EP2 receptor. It exhibits an EC50 value of 200 nM for relaxing cat tracheal rings that express EP2 receptors.

ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid is a natural product of Xanthium, Asteraceae. The catalog number is TN3939 and the CAS number is 55483-24-4. ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid can be used as a reference standard.

7-Hydroxy-8,11,13-abietatrien-19-oic acid is a useful organic compound for research related to life sciences. The catalog number is T125737 and the CAS number is 155473-18-0.

3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-dien-19-al is a natural product for research related to life sciences. The catalog number is TN6274 and the CAS number is 85372-69-6.

17-hydroxy-17-methylandrostane-3,6-dione is a useful organic compound for research related to life sciences and the catalog number is T131620.

17-hydroxy Venturicidin A is a macrolide fungal metabolite originally isolated from Streptomyces. It has antibiotic activity against M. luteus, B. subtilis, and S. aureus and antifungal activity against V. dahlia, Fusarium, and C. tropicalis in a disc assay.

19(R)-hydroxy PGF2α, an ω-1 hydroxylase metabolite of PGF2α present in human semen, exhibits a concentration of approximately 20 µg/ml for both 19(R)-hydroxy PG compounds (F2α and F1α) in fresh samples. This compound demonstrates no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 µM.

12-Hydroxy-8(17),13-labdadien-16,15-olide is a natural product for research related to life sciences. The catalog number is TN2598 and the CAS number is 958885-86-4.

ent-16beta,17-Dihydroxy-19-kauranoic acid is a natural product for research related to life sciences. The catalog number is TN3938 and the CAS number is 3301-61-9.

Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

16-Acetoxy-17-hydroxy-7,13Z-labdadien-15-oic acid is a useful organic compound for research related to life sciences and the catalog number is T130199.

15-Hydroxy-16-kauren-19-oic acid is a useful organic compound for research related to life sciences and the catalog number is T131456.

Lupanine, 17-hydroxy- is a bioactive chemical.

17-Hydroxy-18-dehydroneogrifolin is a natural product for research related to life sciences. The catalog number is TN2654 and the CAS number is 1630936-42-3.

Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα.

19(R)-hydroxy Prostaglandin E1 is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle and is the major prostaglandin in primate semen.

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

16beta,17-Dihydroxy-ent-kaurane-19-oic acid as an anti-HIV principle, it showed significant activity against HIV replication in H9 lymphocyte cells with an EC50 value of 0.8 microgram/mL. It also possesses the activities of decompression and blood viscosi

ent-9-Hydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester is a natural product for research related to life sciences. The catalog number is TN3955 and the CAS number is 81263-96-9.

17-hydroxy-17-methylandrost-4-ene-3,6-dione is a useful organic compound for research related to life sciences and the catalog number is T131621.

(R)-Benzyl 4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate is a useful organic compound for research related to life sciences. The catalog number is T66990 and the CAS number is 1352328-66-5.

19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. It has been used as an internal standard for the quantitative determination of sterols by mass spectroscopic analysis.[1]

19-[(beta-D-glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide is a natural product for research related to life sciences. The catalog number is TN2661 and the CAS number is 919120-78-8.

ent-17-Hydroxykaur-15-en-19-oic acid, a natural compound present in the leaves of the aromatic tree, exhibits an IC50 of 17.63 μg mL against human prostate cells.

ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside is a natural product used in life sciences research, catalog number TN3961, CAS 1245636-01-4.

ent-17-Hydroxykaura-9(11),15-dien-19-oic acid is a natural product from Wedelia trilobata.

13,14-Dihydro-19(R)-hydroxy Prostaglandin E1 (13,14-dihydro-19(R)-hydroxy PGE1) is posited as a theoretical metabolite resulting from the action of ω-1 hydroxylase on 13,14-dihydro PGE1. Its biosynthesis and biological activity remain unreported in scientific literature.

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane is a useful organic compound for research related to life sciences. The catalog number is T66654 and the CAS number is 119302-24-8.

Lupanine, 17-hydroxy-, monohydrochloride is a drug / Therapeutic Agent.

ent-13,16β,17-Trihydroxykauran-19-oic acid is a natural product for research related to life sciences. The catalog number is TN5615 and the CAS number is 142543-30-4.

(R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-Ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66741 and the CAS number is 1516887-33-4.

16-Hydroxy-8(17),13-labdadien-15,16-olid-19-oic acid may show a strong algicidal activity against Raphidocelis subcapitata.

3α-Cinnamoyloxy-9β,17-dihydroxy-ent-kaur-15-en-19-oic acid is a natural product for research related to life sciences. The catalog number is TN5613 and the CAS number is 2186648-60-0.

19-Hydroxy-10-deacetylbaccatin III (compound 13), a taxane with potential antitumor activity, exhibits low cytotoxicity towards A498 and NCI-H226 cell lines, inhibiting their growth by 16.6% and 32% respectively at a concentration of 30 μg mL [1].

Gestonorone is steroid progesterone in the 19-nometroprogesterone and 17α -hydroxyprogesterone groups.