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Search Results for " homologous "

Targets

48

Compounds

1

Natural Products

168

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11014 DFP00173 Aquaporin
DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3.
T9756 AZD-9574 PARP
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.
T2276 RI-1 RI1,RAD51 inhibitor 1 DNA/RNA Synthesis
RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).
T8806 Fluzoparib HS10160,SHR3162 PARP
Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.
T2628 RI-2 DNA/RNA Synthesis
RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells.
T8880 PFM01 Others
PFM01 is an inhibitor of MRE11 endonuclease. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR).
T23974 DDRI-18 DDRI18,DDRI 18 DNA/RNA Synthesis
DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joining (NHEJ) DNA repair and enhances the cytotoxicity of antica...
T8637 DMNB 6-Nitroveratraldehyde DNA-PK
DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human c...
T4339 YU238259 DNA-PK , Others
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.
T6960L PU-H71 HCl PU-H71 HCl(873436-91-0 Free base),Zelavespib HCl HSP , DNA/RNA Synthesis
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of maligna...
T23840 BUR1 BMP upregulator-1,BMP upregulator 1,BUR 1,BUR-1 CDK
BUR1 is a selective BMP upregulator that acts by increasing the expression of Inhibitor of DNA binding 1 and inducing BMP2 and PTGS2 expression.
T63730 NRX-103095 Wnt/beta-catenin
NRX-103095 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP and enhances the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 163 nM.
T10981 DCZ0415 Apoptosis , Others , NF-κB
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ...
T63427 NRX-103094 NRX103094,NRX 103094 Wnt/beta-catenin
NRX-103094 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, which enhances the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.
TP1120L IRBP acetate(211426-18-5 free base) Interphotoreceptor Retinoid Binding Protein Fragment IRBP Others
IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visua...
TQ0232 UNC0646 UNC 0646 Histone Methyltransferase
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646(UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells ...
T14565 BI-671800 AP-761,Cmpd A GPR , Prostaglandin Receptor
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2...
T63516 NRX-252114 NRX252114,NRX 252114 Wnt/beta-catenin
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-...
T4567 Sulfaphenazole Plisulfan,Raziosulfa,Depocid,Depotsulfonamide P450 , Antibacterial
Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1...
T11067 VX-984 M9831 DNA-PK
VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commo...
T33546 Mytilus scp Mytilus small cardioactive peptide
Mytilus scp isolated from Mytilus edulis is homologous to small cardioactive peptides from Aplysia.
T31409 DFHO
DFHO is a Corn homologous ligand that fluoresces yellow upon excitation and is used to image RNA in living cells.
T68398 MI-223
MI-223 is an inhibitor of Mcl-1-stimulated homologous recombination (HR) DNA repair, which leads to sensitization of cancer cells to hydroxyurea- or olaparib-induced DNA replication stress.
T40980 Palmitic acid-13C2 Palmitic acid-13C2
Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (...
T39423 Palmitic acid-13C sodium
Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (...
T40141 Palmitic acid-13C16 sodium Palmitic acid-13C16 sodium
Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated prote...
T80902 Umesolerbart
Umesolerbart (REGN5714) is a monoclonal antibody (mAb) specific to Bet v1 that also binds to homologous allergens in Alder, Hazel, and Hornbeam [1].
TP1120 Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (I...
T10890 CRTh2 antagonist 3 Others
CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of ...
T74501 NHEJ inhibitor-1
NHEJ Inhibitor-1 (Compound C2), a trifunctional Pt(II) complex, mitigates non-homologous end joining (NHEJ)/homologous recombination (HR)-related double strand break (DSB) repairs, combating Cisplatin resistance in non-s...
T36435 SP 10
Peptide originally derived from SARS-CoV Spike (S) protein; corresponds to amino acid residues 668 to 679. Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1.88 nM in biochemical assay). Inhibit...
T76399 PKI(5-22)amide
PKI(5-22)amide, an active inhibitory fragment of the cyclic AMP-dependent protein kinase (PKA) inhibitor, effectively prevents PKA activation. However, it does not reduce the homologous desensitization of CRF1 receptors ...
T36703 CAY10760
CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing Bx...
T62184 NRX-2663
NRX-2663 is an enhancer of the interaction of β-catenin with the homologous E3 ligaseSCFβ-TrCP and has an enhanced effect on the binding of β-catenin to β-TrCP (Kd: 54.8 nM, EC50: 22.9 nM).
T78970 Antitumor agent-96 Apoptosis
"Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor that down-regulates the homologous recombination (HR) pathway by binding to and suppressing the endonuclease functions of MRE11, thereby inducing apoptosis i...
T80024 Cationic Bovine Serum Albumin cBSA, chemically modified cationic bovine serum albumin
Cationic Bovine Serum Albumin, a protein of 583 amino acids with three homologous alpha structural domains, exhibits significant neuroprotective effects against ischemic stroke when used in conjunction with Tanshinone II...
T28536 RI(dl)-2 TFA RI(dl)-2
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM which also inhibits homologous recombination(HR) activity in human cells with IC50 of 3.0 μM[1].
T63846 Gefapixant citrate
Gefapixant citrate is an orally active P2X3 receptor (P2X3R) antagonist that acts on human homologous recombinant hP2X3 (IC50: ~30 nM) and hP2X2/3 (IC50: 100-200 nM). gefapixant citrate can be used to study chronic cough...
T82631 Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly
Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is a 13-mer synthetic peptide with a sequence homologous to seven amino acids of the SV40 T antigen, known for its capability to induce nuclear transport [1].
T36047 LH1307
LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation o...
T36046 LH1306
LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 25 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation ...
T72560 Antitumor agent-81
Antitumor agent-81, a P62-RNF168 agonist with low cytotoxicity, enhances the P62-RNF168 interaction, leading to decreased RNF168-mediated H2A ubiquitination and impaired homologous recombination-mediated DNA repair. Addi...
T79925 T4 UvsX Recombinase DNA/RNA Synthesis
T4 UvsX Recombinase initiates DNA replication on double-stranded templates by catalyzing synapsis with a homologous primer single strand. It significantly enhances the snap-back (hairpin-primed) DNA synthesis catalyzed b...
T63228 Simmiparib SMOCL-9112 Apoptosis , PARP
Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR)-deficient...
T36034 CAY10774
CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50= 15 nM in a homologous time-resolved fret (HTRF) assay).1It increases the activation of Jurkat...
T82847 BNP (1-21), Pro (Human)
BNP (1-21), Pro (Human) is a 21-amino acid peptide and a form of B-Type Natriuretic Peptide (BNP), a cardiac natriuretic hormone. It coexists with the homologous atrial natriuretic peptide in the heart's dual natriuretic...
T36570 KUS121
KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, ...
T83854 BRC4wt TFA
BRC4wt, an acetylated peptide originating from the BRC4 repeat within human BRCA2 (1521-1536), acts as an inhibitor of the BRCA2 and RAD51 protein-protein interaction. When linked to the cationic cell-penetrating peptide...

Compounds

DFP00173
T11014
Synonym:
Target: Aquaporin
AZD-9574
T9756
Synonym:
Target: PARP
RI-1
T2276
Synonym: RI1,RAD51 inhibitor 1
Target: DNA/RNA Synthesis
Fluzoparib
T8806
Synonym: HS10160,SHR3162
Target: PARP
RI-2
T2628
Synonym:
Target: DNA/RNA Synthesis
PFM01
T8880
Synonym:
Target: Others
DDRI-18
T23974
Synonym: DDRI18,DDRI 18
Target: DNA/RNA Synthesis
DMNB
T8637
Synonym: 6-Nitroveratraldehyde
Target: DNA-PK
YU238259
T4339
Synonym:
Target: DNA-PK, Others
PU-H71 HCl
T6960L
Synonym: PU-H71 HCl(873436-91-0 Free base),Zelavespib HCl
Target: HSP, DNA/RNA Synthesis
BUR1
T23840
Synonym: BMP upregulator-1,BMP upregulator 1,BUR 1,BUR-1
Target: CDK
NRX-103095
T63730
Synonym:
Target: Wnt/beta-catenin
DCZ0415
T10981
Synonym:
Target: Apoptosis, Others, NF-κB
NRX-103094
T63427
Synonym: NRX103094,NRX 103094
Target: Wnt/beta-catenin
IRBP acetate(211426-18-5 free base)
TP1120L
Synonym: Interphotoreceptor Retinoid Binding Protein Fragment IRBP
Target: Others
UNC0646
TQ0232
Synonym: UNC 0646
Target: Histone Methyltransferase
BI-671800
T14565
Synonym: AP-761,Cmpd A
Target: GPR, Prostaglandin Receptor
NRX-252114
T63516
Synonym: NRX252114,NRX 252114
Target: Wnt/beta-catenin
Sulfaphenazole
T4567
Synonym: Plisulfan,Raziosulfa,Depocid,Depotsulfonamide
Target: P450, Antibacterial
VX-984
T11067
Synonym: M9831
Target: DNA-PK
Mytilus scp
T33546
Synonym: Mytilus small cardioactive peptide
Target:
DFHO
T31409
Synonym:
Target:
MI-223
T68398
Synonym:
Target:
Palmitic acid-13C2
T40980
Synonym: Palmitic acid-13C2
Target:
Palmitic acid-13C sodium
T39423
Synonym:
Target:
Palmitic acid-13C16 sodium
T40141
Synonym: Palmitic acid-13C16 sodium
Target:
Umesolerbart
T80902
Synonym:
Target:
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)
TP1120
Synonym: IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP
Target:
CRTh2 antagonist 3
T10890
Synonym:
Target: Others
NHEJ inhibitor-1
T74501
Synonym:
Target:
SP 10
T36435
Synonym:
Target:
PKI(5-22)amide
T76399
Synonym:
Target:
CAY10760
T36703
Synonym:
Target:
NRX-2663
T62184
Synonym:
Target:
Antitumor agent-96
T78970
Synonym:
Target: Apoptosis
Cationic Bovine Serum Albumin
T80024
Synonym: cBSA, chemically modified cationic bovine serum albumin
Target:
RI(dl)-2 TFA
T28536
Synonym: RI(dl)-2
Target:
Gefapixant citrate
T63846
Synonym:
Target:
Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly
T82631
Synonym:
Target:
LH1307
T36047
Synonym:
Target:
LH1306
T36046
Synonym:
Target:
Antitumor agent-81
T72560
Synonym:
Target:
T4 UvsX Recombinase
T79925
Synonym:
Target: DNA/RNA Synthesis
Simmiparib
T63228
Synonym: SMOCL-9112
Target: Apoptosis, PARP
CAY10774
T36034
Synonym:
Target:
BNP (1-21), Pro (Human)
T82847
Synonym:
Target:
KUS121
T36570
Synonym:
Target:
BRC4wt TFA
T83854
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TN2444 Batatasin IV 山药 Others
Batatasin IV is identified from Dioscorea opposita which is a a type of homologous medicinal plant and is commonly used as food in daily life.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-01041 FGF-12 Protein, Human, Recombinant Human E. coli
Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present i...
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His) Human Human Cells
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 I...
TMPY-01744 ACVR2A Protein, Human, Recombinant (His) Human HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein of 513 amino acids which is highly homologous (approximately...
TMPY-01447 ACVR2A Protein, Mouse, Recombinant (His) Mouse HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein of 513 amino acids which is highly homologous (approximately...
TMPY-01834 CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) Mouse HEK293
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional...
TMPY-05423 C-MPL Protein, Rat, Recombinant (hFc) Rat HEK293
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPY-03696 LILRA3/CD85e Protein, Human, Recombinant (His) Human HEK293
ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT...
TMPY-01735 Carbonic Anhydrase 2 Protein, Human, Recombinant (His) Human E. coli
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi...
TMPY-02312 CSF3R/G-CSFR Protein, Human, Recombinant (His) Human HEK293
Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regula...
TMPY-05542 ASGR1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR...
TMPY-02702 ASGR1 Protein, Human, Recombinant (His) Human HEK293
The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR...
TMPY-01289 DDR1 Protein, Human, Recombinant (His) Human HEK293
Discoidin domain receptor family, member 1 (DDR1), also known as or CD167a (cluster of differentiation 167a), and Mammary carcinoma kinase 10 (MCK10), belongs to a subfamily of tyrosine kinase receptors with an extracell...
TMPY-02019 CD59 Protein, Human, Recombinant (His) Human HEK293
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-00856 TCCR Protein, Human, Recombinant (hFc) Human HEK293
The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit, and glycoprotein 130. WSX-1/IL-27R, a class I cytokine receptor th...
TMPY-00125 Recombinant Protein A E. coli
Staphylococcal Protein A, or SPA, is a type I membrane protein covalently linked to the cell wall of most strains of the Gram-positive bacterium Staphylococcus aureus. It has high affinity to IgG from various species, fo...
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His) Human HEK293
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPY-00803 Fibronectin Protein, Human, Recombinant (aa 607-1265, His) Human HEK293
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPY-05053 ANGPTL2 Protein, Human, Recombinant (His) Human HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-01279 Transferrin Protein, Human, Recombinant (His) Human HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPY-03295 Transferrin Protein, Mouse, Recombinant (His) Mouse HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPY-01400 CD4 Protein, Human, Recombinant (His) Human HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01226 CD4 Protein, Mouse, Recombinant (His) Mouse HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-05384 CD4 Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPJ-01179 SWSAP1 Protein, Human, Recombinant (His) Human E. coli
SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilizes each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD...
TMPH-01130 C1QTNF3 Protein, Human, Recombinant (His & Myc) Human Baculovirus
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
TMPH-00490 G-CSF Protein, Canine, Recombinant (His & SUMO) Canine E. coli
Single-stranded DNA-binding protein that participates in viral DNA replication, recombination, and repair (Probable). Coats the lagging-strand ssDNA as the replication fork advances. Stimulates the activities of viral DN...
TMPY-04582 ABO Protein, Human, Recombinant (hFc) Human HEK293
ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase) is a Protein Coding gene. Homologous glycosyltransferases α-(1→3)-N-acetylgalactosaminyltransferase (GTA) and α-(1→3)-galactosylt...
TMPH-00491 PNLIPRP1 Protein, Canine, Recombinant (His) Canine Yeast
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance...
TMPH-00492 PNLIPRP1 Protein, Canine, Recombinant (His & SUMO) Canine E. coli
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance...
TMPH-00584 Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His) E. coli E. coli
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a he...
TMPH-01602 LAMA5 Protein, Human, Recombinant (His & SUMO) Human E. coli
Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohe...
TMPH-00549 Epstein-Barr virus (strain GD1) BZLF1 Protein (His & Myc) EBV E. coli
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junct...
TMPY-04462 HK3 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Hexokinase-3, also known as Hexokinase type III, HKIII, and HK3, is a protein that belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme that in humans is encoded by the HK2 gene. Hexokinases phosphorylate gl...
TMPH-00780 CACNA1C Protein, Guinea Pig, Recombinant (His) Guinea pig in vitro E. coli expression system
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded o...
TMPH-02380 RPB5 Protein, Kluyveromyces marxianus, Recombinant (His) Kluyveromyces marxianus E. coli
Nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficien...
TMPH-01291 ERVK-7 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase. Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polyme...
TMPY-01740 IL-1 R9 Protein, Human, Recombinant (His) Human HEK293
X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. ...
TMPY-00851 IL-1 R9 Protein, Human, Recombinant (hFc) Human HEK293
X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. ...
TMPJ-00123 FLT3LG Protein, Mouse, Recombinant (His) Mouse Human Cells
Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and...
TMPK-00653 B7-2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00882 B7-2 Protein, Human, Recombinant (hFc) Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00881 B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00880 B7-2 Protein, Human, Recombinant (His & Avi) Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPJ-01053 UBE2I Protein, Human, Recombinant (GST) Human E. coli
SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin ho...
TMPK-00319 Nectin-3 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous t...
TMPK-00313 Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homologous to the human receptor for poliovirus, and as such ha...
TMPK-00312 Nectin-1 Protein, Human, Recombinant (His & Avi) Human HEK293
Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homologous to the human receptor for poliovirus, and as such ha...
TMPH-00583 Rep Protein, E. coli, Recombinant (GST) E. coli E. coli
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a he...
TMPH-00444 GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc) Chinese hamster E. coli
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand br...
TMPJ-00882 Desmin Protein, Human, Recombinant (His) Human E. coli
Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is th...
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FGF-12 Protein, Human, Recombinant
TMPJ-01041
Species: Human
Expression System: E. coli
FGFRL1 Protein, Human, Recombinant (His)
TMPJ-01224
Species: Human
Expression System: Human Cells
ACVR2A Protein, Human, Recombinant (His)
TMPY-01744
Species: Human
Expression System: HEK293
ACVR2A Protein, Mouse, Recombinant (His)
TMPY-01447
Species: Mouse
Expression System: HEK293
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
TMPY-01834
Species: Mouse
Expression System: HEK293
C-MPL Protein, Rat, Recombinant (hFc)
TMPY-05423
Species: Rat
Expression System: HEK293
LILRA3/CD85e Protein, Human, Recombinant (His)
TMPY-03696
Species: Human
Expression System: HEK293
Carbonic Anhydrase 2 Protein, Human, Recombinant (His)
TMPY-01735
Species: Human
Expression System: E. coli
CSF3R/G-CSFR Protein, Human, Recombinant (His)
TMPY-02312
Species: Human
Expression System: HEK293
ASGR1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05542
Species: Human
Expression System: HEK293
ASGR1 Protein, Human, Recombinant (His)
TMPY-02702
Species: Human
Expression System: HEK293
DDR1 Protein, Human, Recombinant (His)
TMPY-01289
Species: Human
Expression System: HEK293
CD59 Protein, Human, Recombinant (His)
TMPY-02019
Species: Human
Expression System: HEK293
TCCR Protein, Human, Recombinant (hFc)
TMPY-00856
Species: Human
Expression System: HEK293
Recombinant Protein A
TMPY-00125
Species:
Expression System: E. coli
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
TMPY-01104
Species: Human
Expression System: HEK293
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
TMPY-00803
Species: Human
Expression System: HEK293
ANGPTL2 Protein, Human, Recombinant (His)
TMPY-05053
Species: Human
Expression System: HEK293
Transferrin Protein, Human, Recombinant (His)
TMPY-01279
Species: Human
Expression System: HEK293
Transferrin Protein, Mouse, Recombinant (His)
TMPY-03295
Species: Mouse
Expression System: HEK293
CD4 Protein, Human, Recombinant (His)
TMPY-01400
Species: Human
Expression System: HEK293
CD4 Protein, Mouse, Recombinant (His)
TMPY-01226
Species: Mouse
Expression System: HEK293
CD4 Protein, Human, Recombinant (hFc)
TMPY-05384
Species: Human
Expression System: HEK293
SWSAP1 Protein, Human, Recombinant (His)
TMPJ-01179
Species: Human
Expression System: E. coli
C1QTNF3 Protein, Human, Recombinant (His & Myc)
TMPH-01130
Species: Human
Expression System: Baculovirus
G-CSF Protein, Canine, Recombinant (His & SUMO)
TMPH-00490
Species: Canine
Expression System: E. coli
ABO Protein, Human, Recombinant (hFc)
TMPY-04582
Species: Human
Expression System: HEK293
PNLIPRP1 Protein, Canine, Recombinant (His)
TMPH-00491
Species: Canine
Expression System: Yeast
PNLIPRP1 Protein, Canine, Recombinant (His & SUMO)
TMPH-00492
Species: Canine
Expression System: E. coli
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)
TMPH-00584
Species: E. coli
Expression System: E. coli
LAMA5 Protein, Human, Recombinant (His & SUMO)
TMPH-01602
Species: Human
Expression System: E. coli
Epstein-Barr virus (strain GD1) BZLF1 Protein (His & Myc)
TMPH-00549
Species: EBV
Expression System: E. coli
HK3 Protein, Human, Recombinant (His & GST)
TMPY-04462
Species: Human
Expression System: Baculovirus-Insect Cells
CACNA1C Protein, Guinea Pig, Recombinant (His)
TMPH-00780
Species: Guinea pig
Expression System: in vitro E. coli expression system
RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)
TMPH-02380
Species: Kluyveromyces marxianus
Expression System: E. coli
ERVK-7 Protein, Human, Recombinant (His)
TMPH-01291
Species: Human
Expression System: in vitro E. coli expression system
IL-1 R9 Protein, Human, Recombinant (His)
TMPY-01740
Species: Human
Expression System: HEK293
IL-1 R9 Protein, Human, Recombinant (hFc)
TMPY-00851
Species: Human
Expression System: HEK293
FLT3LG Protein, Mouse, Recombinant (His)
TMPJ-00123
Species: Mouse
Expression System: Human Cells
B7-2 Protein, Cynomolgus, Recombinant (His)
TMPK-00653
Species: Cynomolgus
Expression System: HEK293
B7-2 Protein, Human, Recombinant (hFc)
TMPK-00882
Species: Human
Expression System: HEK293
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00881
Species: Human
Expression System: HEK293
B7-2 Protein, Human, Recombinant (His & Avi)
TMPK-00880
Species: Human
Expression System: HEK293
UBE2I Protein, Human, Recombinant (GST)
TMPJ-01053
Species: Human
Expression System: E. coli
Nectin-3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00319
Species: Human
Expression System: HEK293
Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00313
Species: Human
Expression System: HEK293
Nectin-1 Protein, Human, Recombinant (His & Avi)
TMPK-00312
Species: Human
Expression System: HEK293
Rep Protein, E. coli, Recombinant (GST)
TMPH-00583
Species: E. coli
Expression System: E. coli
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)
TMPH-00444
Species: Chinese hamster
Expression System: E. coli
Desmin Protein, Human, Recombinant (His)
TMPJ-00882
Species: Human
Expression System: E. coli
TargetMol