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Cat No. | Product Name | Synonyms | Targets |
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T11014 | DFP00173 | Aquaporin | |
DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3. | |||
T9756 | AZD-9574 | PARP | |
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies. | |||
T2276 | RI-1 | RI1,RAD51 inhibitor 1 | DNA/RNA Synthesis |
RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM). | |||
T8806 | Fluzoparib | HS10160,SHR3162 | PARP |
Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours. | |||
T2628 | RI-2 | DNA/RNA Synthesis | |
RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells. | |||
T8880 | PFM01 | Others | |
PFM01 is an inhibitor of MRE11 endonuclease. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR). | |||
T23974 | DDRI-18 | DDRI18,DDRI 18 | DNA/RNA Synthesis |
DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joining (NHEJ) DNA repair and enhances the cytotoxicity of antica... | |||
T8637 | DMNB | 6-Nitroveratraldehyde | DNA-PK |
DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human c... | |||
T4339 | YU238259 | DNA-PK , Others | |
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays. | |||
T6960L | PU-H71 HCl | PU-H71 HCl(873436-91-0 Free base),Zelavespib HCl | HSP , DNA/RNA Synthesis |
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of maligna... | |||
T23840 | BUR1 | BMP upregulator-1,BMP upregulator 1,BUR 1,BUR-1 | CDK |
BUR1 is a selective BMP upregulator that acts by increasing the expression of Inhibitor of DNA binding 1 and inducing BMP2 and PTGS2 expression. | |||
T63730 | NRX-103095 | Wnt/beta-catenin | |
NRX-103095 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP and enhances the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 163 nM. | |||
T10981 | DCZ0415 | Apoptosis , Others , NF-κB | |
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ... | |||
T63427 | NRX-103094 | NRX103094,NRX 103094 | Wnt/beta-catenin |
NRX-103094 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, which enhances the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM. | |||
TP1120L | IRBP acetate(211426-18-5 free base) | Interphotoreceptor Retinoid Binding Protein Fragment IRBP | Others |
IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visua... | |||
TQ0232 | UNC0646 | UNC 0646 | Histone Methyltransferase |
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646(UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells ... | |||
T14565 | BI-671800 | AP-761,Cmpd A | GPR , Prostaglandin Receptor |
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2... | |||
T63516 | NRX-252114 | NRX252114,NRX 252114 | Wnt/beta-catenin |
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-... | |||
T4567 | Sulfaphenazole | Plisulfan,Raziosulfa,Depocid,Depotsulfonamide | P450 , Antibacterial |
Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1... | |||
T11067 | VX-984 | M9831 | DNA-PK |
VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commo... | |||
T33546 | Mytilus scp | Mytilus small cardioactive peptide | |
Mytilus scp isolated from Mytilus edulis is homologous to small cardioactive peptides from Aplysia. | |||
T31409 | DFHO | ||
DFHO is a Corn homologous ligand that fluoresces yellow upon excitation and is used to image RNA in living cells. | |||
T68398 | MI-223 | ||
MI-223 is an inhibitor of Mcl-1-stimulated homologous recombination (HR) DNA repair, which leads to sensitization of cancer cells to hydroxyurea- or olaparib-induced DNA replication stress. | |||
T40980 | Palmitic acid-13C2 | Palmitic acid-13C2 | |
Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (... | |||
T39423 | Palmitic acid-13C sodium | ||
Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (... | |||
T40141 | Palmitic acid-13C16 sodium | Palmitic acid-13C16 sodium | |
Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated prote... | |||
T80902 | Umesolerbart | ||
Umesolerbart (REGN5714) is a monoclonal antibody (mAb) specific to Bet v1 that also binds to homologous allergens in Alder, Hazel, and Hornbeam [1]. | |||
TP1120 | Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) | IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP | |
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (I... | |||
T10890 | CRTh2 antagonist 3 | Others | |
CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of ... | |||
T74501 | NHEJ inhibitor-1 | ||
NHEJ Inhibitor-1 (Compound C2), a trifunctional Pt(II) complex, mitigates non-homologous end joining (NHEJ)/homologous recombination (HR)-related double strand break (DSB) repairs, combating Cisplatin resistance in non-s... | |||
T36435 | SP 10 | ||
Peptide originally derived from SARS-CoV Spike (S) protein; corresponds to amino acid residues 668 to 679. Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1.88 nM in biochemical assay). Inhibit... | |||
T76399 | PKI(5-22)amide | ||
PKI(5-22)amide, an active inhibitory fragment of the cyclic AMP-dependent protein kinase (PKA) inhibitor, effectively prevents PKA activation. However, it does not reduce the homologous desensitization of CRF1 receptors ... | |||
T36703 | CAY10760 | ||
CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing Bx... | |||
T62184 | NRX-2663 | ||
NRX-2663 is an enhancer of the interaction of β-catenin with the homologous E3 ligaseSCFβ-TrCP and has an enhanced effect on the binding of β-catenin to β-TrCP (Kd: 54.8 nM, EC50: 22.9 nM). | |||
T78970 | Antitumor agent-96 | Apoptosis | |
"Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor that down-regulates the homologous recombination (HR) pathway by binding to and suppressing the endonuclease functions of MRE11, thereby inducing apoptosis i... | |||
T80024 | Cationic Bovine Serum Albumin | cBSA, chemically modified cationic bovine serum albumin | |
Cationic Bovine Serum Albumin, a protein of 583 amino acids with three homologous alpha structural domains, exhibits significant neuroprotective effects against ischemic stroke when used in conjunction with Tanshinone II... | |||
T28536 | RI(dl)-2 TFA | RI(dl)-2 | |
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM which also inhibits homologous recombination(HR) activity in human cells with IC50 of 3.0 μM[1]. | |||
T63846 | Gefapixant citrate | ||
Gefapixant citrate is an orally active P2X3 receptor (P2X3R) antagonist that acts on human homologous recombinant hP2X3 (IC50: ~30 nM) and hP2X2/3 (IC50: 100-200 nM). gefapixant citrate can be used to study chronic cough... | |||
T82631 | Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly | ||
Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is a 13-mer synthetic peptide with a sequence homologous to seven amino acids of the SV40 T antigen, known for its capability to induce nuclear transport [1]. | |||
T36047 | LH1307 | ||
LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation o... | |||
T36046 | LH1306 | ||
LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 25 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation ... | |||
T72560 | Antitumor agent-81 | ||
Antitumor agent-81, a P62-RNF168 agonist with low cytotoxicity, enhances the P62-RNF168 interaction, leading to decreased RNF168-mediated H2A ubiquitination and impaired homologous recombination-mediated DNA repair. Addi... | |||
T79925 | T4 UvsX Recombinase | DNA/RNA Synthesis | |
T4 UvsX Recombinase initiates DNA replication on double-stranded templates by catalyzing synapsis with a homologous primer single strand. It significantly enhances the snap-back (hairpin-primed) DNA synthesis catalyzed b... | |||
T63228 | Simmiparib | SMOCL-9112 | Apoptosis , PARP |
Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR)-deficient... | |||
T36034 | CAY10774 | ||
CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50= 15 nM in a homologous time-resolved fret (HTRF) assay).1It increases the activation of Jurkat... | |||
T82847 | BNP (1-21), Pro (Human) | ||
BNP (1-21), Pro (Human) is a 21-amino acid peptide and a form of B-Type Natriuretic Peptide (BNP), a cardiac natriuretic hormone. It coexists with the homologous atrial natriuretic peptide in the heart's dual natriuretic... | |||
T36570 | KUS121 | ||
KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, ... | |||
T83854 | BRC4wt TFA | ||
BRC4wt, an acetylated peptide originating from the BRC4 repeat within human BRCA2 (1521-1536), acts as an inhibitor of the BRCA2 and RAD51 protein-protein interaction. When linked to the cationic cell-penetrating peptide... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2444 | Batatasin IV | 山药 | Others |
Batatasin IV is identified from Dioscorea opposita which is a a type of homologous medicinal plant and is commonly used as food in daily life. |
Cat No. | Product Name | Species | Expression System |
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TMPJ-01041 | FGF-12 Protein, Human, Recombinant | Human | E. coli |
Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present i... | |||
TMPJ-01224 | FGFRL1 Protein, Human, Recombinant (His) | Human | Human Cells |
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 I... | |||
TMPY-01744 | ACVR2A Protein, Human, Recombinant (His) | Human | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein of 513 amino acids which is highly homologous (approximately... | |||
TMPY-01447 | ACVR2A Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein of 513 amino acids which is highly homologous (approximately... | |||
TMPY-01834 | CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) | Mouse | HEK293 |
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional... | |||
TMPY-05423 | C-MPL Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o... | |||
TMPY-03696 | LILRA3/CD85e Protein, Human, Recombinant (His) | Human | HEK293 |
ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT... | |||
TMPY-01735 | Carbonic Anhydrase 2 Protein, Human, Recombinant (His) | Human | E. coli |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi... | |||
TMPY-02312 | CSF3R/G-CSFR Protein, Human, Recombinant (His) | Human | HEK293 |
Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regula... | |||
TMPY-05542 | ASGR1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR... | |||
TMPY-02702 | ASGR1 Protein, Human, Recombinant (His) | Human | HEK293 |
The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR... | |||
TMPY-01289 | DDR1 Protein, Human, Recombinant (His) | Human | HEK293 |
Discoidin domain receptor family, member 1 (DDR1), also known as or CD167a (cluster of differentiation 167a), and Mammary carcinoma kinase 10 (MCK10), belongs to a subfamily of tyrosine kinase receptors with an extracell... | |||
TMPY-02019 | CD59 Protein, Human, Recombinant (His) | Human | HEK293 |
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran... | |||
TMPY-00856 | TCCR Protein, Human, Recombinant (hFc) | Human | HEK293 |
The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit, and glycoprotein 130. WSX-1/IL-27R, a class I cytokine receptor th... | |||
TMPY-00125 | Recombinant Protein A | E. coli | |
Staphylococcal Protein A, or SPA, is a type I membrane protein covalently linked to the cell wall of most strains of the Gram-positive bacterium Staphylococcus aureus. It has high affinity to IgG from various species, fo... | |||
TMPY-01104 | Coagulation factor XI/F11 Protein, Human, Recombinant (His) | Human | HEK293 |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p... | |||
TMPY-00803 | Fibronectin Protein, Human, Recombinant (aa 607-1265, His) | Human | HEK293 |
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ... | |||
TMPY-05053 | ANGPTL2 Protein, Human, Recombinant (His) | Human | HEK293 |
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism... | |||
TMPY-01279 | Transferrin Protein, Human, Recombinant (His) | Human | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-03295 | Transferrin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-01400 | CD4 Protein, Human, Recombinant (His) | Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-01226 | CD4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-05384 | CD4 Protein, Human, Recombinant (hFc) | Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPJ-01179 | SWSAP1 Protein, Human, Recombinant (His) | Human | E. coli |
SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilizes each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD... | |||
TMPH-01130 | C1QTNF3 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. | |||
TMPH-00490 | G-CSF Protein, Canine, Recombinant (His & SUMO) | Canine | E. coli |
Single-stranded DNA-binding protein that participates in viral DNA replication, recombination, and repair (Probable). Coats the lagging-strand ssDNA as the replication fork advances. Stimulates the activities of viral DN... | |||
TMPY-04582 | ABO Protein, Human, Recombinant (hFc) | Human | HEK293 |
ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase) is a Protein Coding gene. Homologous glycosyltransferases α-(1→3)-N-acetylgalactosaminyltransferase (GTA) and α-(1→3)-galactosylt... | |||
TMPH-00491 | PNLIPRP1 Protein, Canine, Recombinant (His) | Canine | Yeast |
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance... | |||
TMPH-00492 | PNLIPRP1 Protein, Canine, Recombinant (His & SUMO) | Canine | E. coli |
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance... | |||
TMPH-00584 | Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His) | E. coli | E. coli |
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a he... | |||
TMPH-01602 | LAMA5 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohe... | |||
TMPH-00549 | Epstein-Barr virus (strain GD1) BZLF1 Protein (His & Myc) | EBV | E. coli |
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junct... | |||
TMPY-04462 | HK3 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Hexokinase-3, also known as Hexokinase type III, HKIII, and HK3, is a protein that belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme that in humans is encoded by the HK2 gene. Hexokinases phosphorylate gl... | |||
TMPH-00780 | CACNA1C Protein, Guinea Pig, Recombinant (His) | Guinea pig | in vitro E. coli expression system |
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded o... | |||
TMPH-02380 | RPB5 Protein, Kluyveromyces marxianus, Recombinant (His) | Kluyveromyces marxianus | E. coli |
Nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficien... | |||
TMPH-01291 | ERVK-7 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase. Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polyme... | |||
TMPY-01740 | IL-1 R9 Protein, Human, Recombinant (His) | Human | HEK293 |
X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. ... | |||
TMPY-00851 | IL-1 R9 Protein, Human, Recombinant (hFc) | Human | HEK293 |
X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. ... | |||
TMPJ-00123 | FLT3LG Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and... | |||
TMPK-00653 | B7-2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00882 | B7-2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00881 | B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00880 | B7-2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPJ-01053 | UBE2I Protein, Human, Recombinant (GST) | Human | E. coli |
SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin ho... | |||
TMPK-00319 | Nectin-3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous t... | |||
TMPK-00313 | Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homologous to the human receptor for poliovirus, and as such ha... | |||
TMPK-00312 | Nectin-1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions. They are highly homologous to the human receptor for poliovirus, and as such ha... | |||
TMPH-00583 | Rep Protein, E. coli, Recombinant (GST) | E. coli | E. coli |
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a he... | |||
TMPH-00444 | GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc) | Chinese hamster | E. coli |
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand br... | |||
TMPJ-00882 | Desmin Protein, Human, Recombinant (His) | Human | E. coli |
Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is th... | |||
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