| T0120 |
Voriconazole |
Voriconazole is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A. |
| T0146 |
Vagistat |
Tioconazole is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal...
|
| T0344 |
Miconazole |
Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion. |
| T0444 |
Econazole |
Econazole is an imidazole derivative that is commonly used as a topical antifungal agent. |
| T0444L |
Econazole nitrate |
Econazole nitrate (Spectazole) is an imidazole class antifungal medicine. |
| T0506 |
Clotrimazole |
Clotrimazole, an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol. |
| T0681 |
Rifampicin |
Rifampicin is an antibacterial drug of the class of rifamycin. |
| T0688 |
Ganciclovir |
Ganciclovir is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications fr...
|
| T0863 |
Dendrid |
Idoxuridine is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent. |
| T0868 |
Cefepime Dihydrochloride Monohydrate |
Cefepime Dihydrochloride Monohydrate is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived...
|
| T0884 |
n-Docosanol |
Docosanol is a saturated 22-carbon aliphatic alcohol with antiviral activity. Docosanol has a distinct mechanism of action and inhibits fusion between the pl...
|
| T1000 |
Chlorhexidine |
Chlorhexidine is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the n...
|
| T1000L |
Chlorhexidine Acetate |
Chlorhexidine acetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. |
| T1079 |
Metronidazole |
Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. |
| T1147 |
Chlorhexidine hydrochloride |
Chlorhexidine hydrochloride is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. |
| T1190 |
Cefmenoxime hydrochloride |
Cefmenoxime hydrochloride is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive an...
|
| T1290 |
Oxiconazole nitrate |
Oxiconazole Nitrate is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of act...
|
| T1388 |
Fluconazole |
Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. |
| T1643 |
Penciclovir |
Penciclovir is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subs...
|
| T2213 |
Terconazole |
Terconazole is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting bi...
|
| T4202 |
Delamanid |
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell ...
|
| T6207 |
SC144 |
SC144 is an orally active small-molecule gp130 inhibitor. |
| T4201 |
Avibactam sodium |
Avibactam is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases). |
| TCS1772 |
Dehydroabietic acid |
1. Dehydroabietic acid (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing pl...
|
| T3S1534 |
Secoxyloganin |
Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell li...
|
| T4960 |
VASICINE |
Vasicine is oxytocic and abortifacient agents.Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disea...
|
| T5188 |
GC376 sodium |
GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM. |
| T3S1088 |
Isoforsythiaside |
Isoforsythiaside has antioxidant, and antibacterial activities. |
| T3S0631 |
Fuziline |
Fuziline shows significant insecticidal activity against Nilaparvata legen and Aphis medicagini. Fuziline shows activity against pentobarbital sodiuminduced car...
|
| T5544 |
2-Furoic acid |
2-Furoic acid, an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessi...
|
| T5602 |
Benzylpenicillin potassium |
Benzylpenicillin potassium is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. |
| T5691 |
paulownin |
Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity. |
| T5776 |
pimpinellin |
Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity. |
| T5778 |
5,7-DIMETHOXYFLAVONE |
5,7-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential. |
| T5746 |
Dictamnine |
Dictamnine shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytoto...
|
| T7733 |
Cefotaxime |
Cefotaxime is an inhibitor of penicillin binding protein. |
| TL0015 |
Pyromeconic acid |
Pyromeconic acid and derivatives thereof are potent inhibitors of endonuclease |
| T8247 |
(+)-Aromadendrene |
(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria. |
| T8121 |
Octacosanoic acid |
Octacosanoic acid has antiplatelet and antithrombotic effects. |
| T7999 |
7-Hydroxyflavanone |
7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates. |
| T8019 |
Sorbic acid |
Sorbic acid is a natural product that inhibits various bacteria, including sporeformers, |
| T7869 |
Nicoform |
Nicoform is an antimicrobial agent. |
| T8133 |
SulfadiMethoxine sodium |
Sulfadimethoxine is a antimicrobial agent, treatment of respiratory, urinary tract, enteric, and soft tissue infections |
| TN1012 |
Febrifugine |
Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by to...
|
| TN1063 |
Calycanthine |
D-calycanthine has antifungal activity, it shows significant inhibitory activities against five plant pathogenic fungi Exserohilum turcicum, Bipolaris maydis, A...
|
| TN1084 |
Desmethylbellidifolin |
Desmethylbellidifolin is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activ...
|
| TN1108 |
Kaempferol 3-O-beta-sophoroside |
Kaempferol 3-O-beta-sophoroside has antibacterial and antiviral activities. |
| TN1113 |
Vincetoxicoside B |
Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activitie...
|
| TN1114 |
Carabrone |
Some of carabrone derivatives exhibit antifungal activities in vitro or in vivo, the compounds with a pyridinyl residue can either efficiently inhibit spore ger...
|
| TN1120 |
Osthenol |
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promo...
|
| TN1121 |
Evocarpine |
Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels. |
| TN1130 |
Yadanziolide A |
Yadanziolide A shows strong antiviral activity. |
| TN1133 |
Isocolumbin |
Isocolumbin has anti-inflammatory, and antimicrobial activities. |
| TN1145 |
Isofebrifugine |
Isofebrifugine shows antimalarial activity. |
| TN1162 |
1,2-Benzenedicarboxylic acid |
1,2-Benzenedicarboxylic acid is one kind of allelochemical shows stronger allelopathic effect on itself than on wheat and pigeonpea. |
| TN1167 |
1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside |
1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside shows certain antibacterial activity. |
| TN1203 |
2,3,8-Tri-O-methylellagic acid |
2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus ...
|
| TN1213 |
2-(Hydroxymethyl)anthraquinone |
2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc. |
| TN1215 |
2'-Methoxykurarinone |
2'-Methoxykurarinone has strong alpha-glucosidase inhibitory activities, with IC(50) values of 155 microM. 2'-Methoxykurarinone is a noncompetitive inhibitor of...
|
| TN1242 |
3,8-Di-O-methylellagic acid |
3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a...
|
| TN1262 |
3-O-Feruloylquinic acid |
3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro. |
| TN1301 |
6,8-Diprenylgenistein |
6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria. |
| TN1329 |
7-Ethoxyrosmanol |
7-Ethoxyrosmanol has cytotoxic and antimicrobial activities. |
| TN1342 |
8-Epidiosbulbin E acetate |
8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci...
|
| TN1344 |
8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone |
8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone may have antifungal activity against phytopathogenic and human pathogenic fungi. |
| TN1349 |
9-Hydroxycalabaxanthone |
9-Hydroxycalabaxanthone exhibits cytotoxicity against the HT-29 cell line with ED50 values of 9.1 microM. The combination of 9-hydroxycalabaxanthone with α±-m...
|
| TN1409 |
Asimilobine |
(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α±-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhi...
|
| TN1417 |
Azadirachtin |
Azadirachtin has antifungal activity, it used as insecticides. |
| TN1427 |
Baicalin methyl ester |
Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT). |
| TN1436 |
Methyl 4-Hydroxyphenylacetate |
Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV). |
| TN1442 |
Betulinic acid methyl ester |
Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell...
|
| TN1444 |
bis[6-(5,6-dihydrochelerythrinyl)]amine |
BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). |
| TN1451 |
Brevifolincarboxylic acid |
Brevifolincarboxylic acid shows moderate antibacterial activity against Salmonella enteritidis , Salmonella typhimurium , and Salmonella abony, it (IC50 = 18.0 ...
|
| TN1453 |
Bruceantinol |
Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC5...
|
| TN1481 |
Cerebroside B |
Cerebroside B1b has antiulcerogenic activity. |
| TN1521 |
Colutehydroquinone |
Colutehydroquinone and colutequinone are antifungal isoflavonoids from Colutea arborescens. |
| TN1522 |
Combretol |
Combretol has leishmanicidal activity, it showed moderate activity (growth inhibition 87.3 and 73.0 %, respectively, at 50 μM) against a multidrug-resistant L....
|
| TN1527 |
Corynoxidine |
Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains. It inhibits acetylcholinesterase activ...
|
| TN1530 |
Cowaxanthone B |
Cowaxanthone B shows weak antibacterial activity. |
| TN1531 |
Cratoxylone |
Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC50 value belows 3 μM. |
| TN1556 |
Decarine |
Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarin...
|
| TN1561 |
Dehydroglaucine |
Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, ...
|
| TN1568 |
Deoxyartemisinin |
Deoxyartemisinin can inhibit microbial growth and reproduction,and is therefore likely to influence biochemical reactions in soils. |
| TN1569 |
Deoxylapachol |
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white...
|
| TN1594 |
DL-Syringaresinol |
(+)-Syringaresinol shows inhibitory activity of Helicobacter pylori motility with the IC50 value is 50 microg/ml. |
| TN1632 |
Euparin |
Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it e...
|
| TN1668 |
Ganoderic acid Y |
Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating. |
| TN1689 |
Glabranin |
Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereo...
|
| TN1695 |
Globulol |
Globulol shows antimicrobial activity against Xanthomonas vesicatoria and Bacillus subtilis, the IC50 value of 158.0 microg/ mLand 737.2 microg/ mL, respectivel...
|
| TN1699 |
Glyasperin D |
Glyasperin D possesses weak anti-Helicobacter pylori activity. |
| TN1714 |
Grosvenorin |
Grosvenorine exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an importa...
|
| TN1722 |
Hamamelitannin |
Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans...
|
| TN1772 |
Isoastilbin |
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) w...
|
| TN1790 |
Isopteropodine |
Isopteropodine has antimicrobial activity, it shows strong apoptotic effects on acute leukaemic lymphoblasts, it also shows an ability to stimulate the immune s...
|
| TN1792 |
Isorhamnetin 3-glucoside-7-rhamnoside |
An anti-oxidative composition containing isorhamnetin-3-glucoside-7-rhamnoside (IGR)isolated from Hippophae rhamnoides L. is provided to ensure antioxidative, a...
|
| TN1821 |
Kaempferol 3-O-arabinoside |
Kaempferol-3-O-α±-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antio...
|
| TN1838 |
Kulactone |
Kulactone has cytotoxic effects, with IC50 values of 5.6-21.2ug/mL, it inhibited (ED(50) 2.5-6.2 microg/mL) the P388 cancer cell line. |
| TN1839 |
Kumatakenin |
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL. |
| TN1860 |
Licoflavone B |
Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities. |
| TN1861 |
Licoflavone C |
Licoflavone C has cytotoxic, and antioxidative effects, it has protective effect toward the chromosome damage induced by DAU or MMC in cultured human peripheral...
|
| TN1862 |
Licoflavonol |
Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibi...
|
| TN1864 |
Licoisoflavone B |
Licoisoflavone B is an inhibitor of germ tube growth in the arbuscular mycorrhizal (AM) fungus Gigaspora margarita, it can strongly inhibit germ tube growth at ...
|
| TN1877 |
Lonicerin |
Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albi...
|
| TN1897 |
Luteone |
Luteone possesses antifungal activity sufficient to support its proposed role as pre-infectional resistance factors. |
| TN1905 |
Magnolioside |
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a mode...
|
| TN1906 |
Magnoloside A |
Magnoloside A has potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 ug/ml. |
| TN1930 |
Methylenetanshinquinone |
Methylenetanshinquinone shows antiplasmodial and antitrypanosomal activity, it is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum. |
| TN1931 |
Methyllinderone |
Methyllinderone is a human chymase inhibitor, it has antioxidant property, it also shows moderate to weak antifungal activities against various pathogenic fungi...
|
| TN1938 |
Mogroside VI |
Lo Han Kuo extract is a high intensive sweetening agent with desirable health benefits, such as prevention of dental caries through specific antibacterial prope...
|
| TN1955 |
Mucrolidin |
Mucrolidin shows weak antibacterial activity. |
| TN1977 |
Neochamaejasmine B |
Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus. |
| TN1979 |
Neocnidilide |
Neocnidilide has insecticidal activity, it exhibits LC50 values of 9.90 micromol/mL of diet concentration against larvae of D. melanogaster. Neocnidilide has an...
|
| TN1985 |
Neoprzewaquinone A |
Neoprzewaquinone A has algicidal effect on M. aeruginosa , with EC50 of 4.68 mg /L, the potential inhibition mechanisms are neo-przewaquinone A caused M. aerugi...
|
| TN1991 |
Norchelerythrine |
Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong...
|
| TN1993 |
Norsanguinarine |
Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic act...
|
| TN2011 |
Ombuoside |
Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays. |
| TN2027 |
Oxysanguinarine |
Oxysanguinarine possesses antiplatelet aggregation activity, it has potential inhibitory properties against dengue virus. |
| TN2032 |
Pachypodol |
Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas a...
|
| TN2047 |
Pendulone |
Pendulone could be a valuable chemopreventive agent, it shows strong inhibition on the effect of the cell cycle induced by TPA and shows potent anti-tumor-promo...
|
| TN2058 |
Persicogenin |
Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits c...
|
| TN2074 |
Pilocarpine |
Pilocarpine has been used to treat glaucoma, ocular hypertension and xerostomia. |
| TN2085 |
Piperlonguminine |
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, ant...
|
| TN2101 |
Primin |
Primin has antimycobacterial, and strong antineoplastic actions. |
| TN2160 |
Roemerine |
Roemerine is a potential active xanthine oxidase(XOD) inhibitor, XOD is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the d...
|
| TN2172 |
Saikosaponin I |
Saikosaponin I shows strong inhibition activity against influenza virus WSN33. |
| TN2190 |
Scoulerine |
Scoulerine shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0....
|
| TN2219 |
Sophoraisoflavone A |
Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ t...
|
| TN2246 |
Swertiajaponin |
Swertiajaponin possesses antimicrobial activity.
|
| TN2249 |
(+)-Syringaresinol |
(+)-Syringaresinol shows antioxidant potential, it exhibits cytoprotective activity in cultured MCF-7 cells stressed by H2O2. |
| TN2256 |
Taccalonolide B |
Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibit...
|
| TN2271 |
Thalrugosaminine |
Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug/ml and Staphylococcus species is the most sensitive strains. Thalrugosaminin...
|
| TN2277 |
Torachrysone 8-O-glucoside |
Torachryson-8-O-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes. |
| TN2278 |
Torachrysone |
Torachrysone shows promising antioxidant activity. Torachrysone, toralactone , aloe-emodin, rhein and emodin show noticeable antibacterial effects on four strai...
|
| TN2279 |
Totarol |
Totarol has anti-bacteria effect by restraining bacterial growth by perturbing the cell division and proliferation, including several pathogenic Gram-positive b...
|
| TN2293 |
Valechlorine |
Valeranone shows antileishmanial and cytotoxic activity. |
| TN2311 |
Wulignan A1 |
Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) ac...
|
| TN2315 |
Xanthopurpurin |
Xanthopurpurin shows antiviral activity, it can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpuri...
|
| TN2321 |
Yadanzioside L |
Yadanzioside L shows strong antiviral activity. |
| TN1099 |
Dihydroevocarpine |
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is ...
|
| TN1144 |
Enmein |
Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml |
| TN1302 |
6,8-Diprenylorobol |
6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected i...
|
| TN1375 |
alpha-Lapachone |
alpha-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi. |
| TN1402 |
Arjungenin |
Arjungenin shows α²-glucuronidase inhibitory activity, it shows antiviral, and anti-inflammatory activities. |
| TN1463 |
Calycanthoside |
Isofraxidin-7-O-glucoside(Calycanthoside ) has the anti-inflammatory effect, it has inhibitory activity on NO production.It also shows antibacterial activity. |
| TN1466 |
Canthin-6-one |
Canthin-6-one has antimicrobial, cytotoxic, antiproliferative and proapoptotic effects, possibly by interfering with the G2/M transition; it also has antiinflam...
|
| TN1484 |
Cheilanthifoline |
Cheilanthifoline has anti-osteoclastogenic property, it gives significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation...
|
| TN1513 |
Clitorin |
Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential. |
| TN1526 |
Corydalmine |
Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spo...
|
| TN1538 |
Curzerenone |
Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52). |
| TN1560 |
Dehydroeffusol |
Dehydroeffusol possesses anti-cancer, anxiolytic and sedative properties, it may antagonize the spasmogenic activity of various agents, and therefore, could be ...
|
| TN1637 |
Eurycomalactone |
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits pro...
|
| TN1673 |
Garcinone C |
Garcinone C is a potent inhibitor of AChE. |
| TN1733 |
Hesperetin 7-O-glucoside |
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibitio...
|
| TN1778 |
Isoformononetin |
Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 ce...
|
| TN1814 |
Juncusol |
Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; it can induce caspase-3-mediated cytotoxicity in HT22 ce...
|
| TN1842 |
Kushenol I |
Kushenol I is a GABAA receptor modulator, it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).Kushenol I is shown to be acti...
|
| TN1853 |
Lariciresinol |
Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel ant...
|
| TN1928 |
Methyl rosmarinate |
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmar...
|
| TN2111 |
Prunin |
Prunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-r...
|
| TN2120 |
Quassin |
Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion. |
| TN2252 |
Syrosingopine |
Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase i...
|
| TN1041 |
Quercimeritrin |
Quercimeritrin has antibacterial activity, it shows promising activity against Staphylococcus aureus. |
| TN1117 |
Veraguensin |
Veraguensin shows activity against trypomastigote T. cruzi., it shows high antileishmanial activity. |
| TN1343 |
8-Geranyloxypsoralen |
8-Geranyloxypsoralen inhibits α²-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat a...
|
| TN1432 |
Bacopasaponin C |
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property. |
| TN1694 |
Gliotoxin |
Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signali...
|
| TN1703 |
Glycyrin |
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice. |
| TN1913 |
Marmin |
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and se...
|
| TN1919 |
Medioresinol |
Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in t...
|
| TN2063 |
Physalin B |
Physalin B shows antimalarial, anti-Trypanosoma cruzi, anti-bacterial, anti- leukemia activities, it has the potential to be developed as an effective chemother...
|
| TN2078 |
Pinocembrin chalcone |
Pinocembrin chalcone has tyrosinase inhibitory activity.It also shows antimutagenic effect, which is mainly due to the inhibition of the first step of enzymatic...
|
| Fr14115 |
Terpineol |
Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and carioge...
|
| Fr14298 |
2'-Hydroxy-4'-methylacetophenone |
2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. 2'-Hydroxy-4'-methylacetophenone has...
|
| T2S1115 |
Albaspidin AA |
Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM). It may have in vitro nematocidal ...
|
| T2S1635 |
3-Isomangostin |
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has ...
|
| T2S1727 |
Lycorenine |
Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic ...
|
| T2S2363 |
Corydine |
Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant...
|
| T3831 |
Licoricone |
Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. |
| T3897 |
Isoschaftoside |
Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the...
|
| T3S0006 |
Methyl ferulate |
Methyl ferulate is a possible inhibitor of the mitogen activated phosphor kinase pathway, it could be a potential anti-inflammatory agent isolated for the first...
|
| T3S1692 |
Octahydrocurcumin |
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechan...
|
| T4131 |
Arjunic acid |
Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ...
|
| T4237 |
Rubiadin 1-methyl ether |
Rubiadin-1-methyl ether probed as Type I photosensitizers. Rubiadin 1-methyl ether decreases the number of parasites (schizonts) in a dose-dependent manner, and...
|
| T4484 |
1,7-Dihydroxy-2,3-methylenedioxyxanthone |
1,7-Dihydroxy-2,3-methylenedioxyxanthone has antiulcerogenic, anti-oxidation, and antihyperalgesic activities, it can inhibit the carrageenan-induced hyperalges...
|
| T4672 |
Brevilin A |
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor ...
|
| T5527 |
Anigorufone |
Anigorufone is a phytoalexin, it shows striking antinematode activity. Anigorufone has shown inhibitory activity on the growth of the germinative tube of Fusari...
|
| T5722 |
Nevadensin |
Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcin...
|
| T7059 |
alpha-Dihydroartemisinin |
Dihydroartemisinin is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs, is recommended as the first-line anti-m...
|
| T9113 |
Myristicin |
Myristicin is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also...
|
| TC0017 |
Haplopine |
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the ...
|
| TJS1382 |
Taraxerone |
Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease ...
|
| TJS1748 |
Methyl protogracillin |
Methyl protoneogracillin shows cytotoxic activitiy against the cancer cell line of K562 in vitro as antineoplastic agents. It can cause morphological abnormalit...
|
| TJS2216 |
Asperglaucide |
Asperglaucide shows some nematocidal property against M. incognita. |
| TL0013 |
Heraclenin |
Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat ...
|
| TL0016 |
Sulforaphene |
Sulforaphene may be a potential anti- triple negative breast cancer natural compound and its /\''antiproliferation effects may be mediated by tumor suppressor E...
|
| TL0018 |
Lobelin |
Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the ind...
|
| TN2392 |
9,17-Octadecadiene-12,14-diyne-1,11,16-triol |
9,17-Octadecadiene-12,14-diyne-1,11,16-triol shows antibacterial activity against Bacillus subtilis and Pseudomonas fluorescens, antifungal activity against Cla...
|
| TN2417 |
Furomollugin |
Furomollugin has antiviral activity, it can strongly suppress the secretion of hepatitis B surface antigen (HBsAg), with IC50 = 2.0 micrograms/mL, in human hepa...
|
| TN2475 |
1(10)-Aristolen-2-one |
1(10)-Aristolen-2-one has antifungal activity. |
| TN2485 |
1,2-Dihydrotanshinquinone |
1,2 Dihydrotanshinquinone is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum. |
| TN2489 |
1,3,7-Trihydroxy-2-prenylxanthone |
1,3,7-Trihydroxy-2-prenylxanthone shows weak antibacterial activity against the bacterium. |
| TN2495 |
1,4,7-Eudesmanetriol |
1α,4β,7β-Eudesmanetriol and 1β,4β,7β-Eudesmanetriol can inhibit growth of Pseudomonas stutzeri with a MIC value of 117 uM, they also show remarkable activ...
|
| TN2515 |
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one |
(4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with ...
|
| TN2524 |
1-Acetyl-beta-carboline |
Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA. |
| TN2548 |
1-Methoxyberberine |
1-Methoxyberberine chloride is a potential antifungal agent. |
| TMA2418 |
1-Methoxyphaseollidin |
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Met...
|
| TN2567 |
10-Hydroxycanthin-6-one |
10-Hydroxycanthin-6-one has potential to be an antimicrobial agent. 10-Hydroxycanthin-6-one has in vitro antimalarial activity; it also has cytotoxic activity, ...
|
| TN2579 |
11,13-Dihydroivalin |
Standard reference |
| TN2623 |
14-Deoxy-17-hydroxyandrographolide |
Standard reference |
| TN2625 |
14-Deoxycoleon U |
14-Deoxycoleon U has anti-termitic activity, it is highly active against both wood-decay fungi. 14-Deoxycoleon U shows antibacterial activity against the Gram-p...
|
| TN2626 |
14-Norpseurotin A |
14-Norpseurotin A shows good antileishmanial and moderate anticancer activities. It also displays significant antimicrobial activities against Escherichia coli,...
|
| TMA0164 |
15-Hydroxydehydroabietic acid |
15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities. |
| TN2650 |
16-Oxocleroda-3,13E-dien-15-oic acid |
16-Oxocleroda-3,13E-dien-15-oic acid shows antiplasmodial activity. |
| TN2685 |
2,3,24-Trihydroxy-12-ursen-28-oic acid |
2α,3α,24-Trihydroxyurs-12-en-28-oic acid, a triterpenoid phytoalexin, shows antifungal activity against the fungus mentioned. It also shows in vitro cytotoxic...
|
| TN2686 |
2,3,24-Trihydroxyolean-12-en-28-oic acid |
2α,3α,24-Trihydroxyolean-12-en-28-oic acid, a triterpenoid phytoalexin, isolated from peel of unripe fruits of nectarine (Prunus persica cv Fantasia), shows a...
|
| TN2697 |
2,3-Dihydrohinokiflavone |
2,3-Dihydrohinokiflavone is a suppressor of matrix metalloproteinases (MMPs) gene expression. It (IC50 =1.6uM) shows strong activity against Leishmania. |
| TN2711 |
2'',4''-Di-O-(E-p-coumaroyl)afzelin |
Antimicrobial agent. |
| TN2723 |
Jatrophane 3 |
(2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R*,...
|
| TN2727 |
Jatrophane 2 |
2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17),11E-diene (Jatrophane 2 ) exhibits significant antifeedant activity against a generalist plant-fe...
|
| TN2728 |
Jatrophane 4 |
(2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R*,...
|
| TN2730 |
2,5-Dihydroxybenzaldehyde |
2,5-Dihydroxybenzaldehyde has antioxidant activity. |
| TN2736 |
2',6'-Dihydroxy-4'-methoxyacetophenone |
2',6'-Dihydroxy-4'-methoxyacetophenone is a phytoalexin after fungal inoculation with Botrytis cinerea or UV light irradiation, it has spore germination inhibit...
|
| TN2738 |
2,6-Dimethoxy-1-acetonylquinol |
2,6-Dimethoxy-1-acetonylquinol shows varying degrees of in vitro antimalarial activity against Plasmodium falciparum. It is devoid of significant cytotoxicity t...
|
| TN2747 |
2-Acetoxy-3-deacetoxycaesaldekarin E |
2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro. |
| TN2755 |
2-Desoxy-4-epi-pulchellin |
2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with...
|
| TN2760 |
2-Hydroxy-1,8-cineole |
1. 2-endo-Hydroxy-1,8-cineole shows antimicrobial and bactericidal activities against against test bacteria (Staphylococcus aureus, Escherichia coli, and Pseudo...
|
| TN2767 |
2'-Hydroxygenistein |
2'-Hydroxygenistein has antifungal activity, dimerization of it causes a remarkable increase of antifungal activity. It shows significant concentration-dependen...
|
| TN2772 |
2-Methoxyanofinic acid |
2-Methoxyanofinic acid is active against the plant pathogenic fungus Cladosporium cucumerinum. |
| TN2774 |
2-Methoxyphenalen-1-one |
2-Methoxy-1H-phenalen-1-one (2-Methoxyphenalen-1-one) displays significantly enhanced activity against Mycosphaerella fijiensis in comparison with other phenylp...
|
| TN2798 |
20-Deoxocarnosol |
20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoa...
|
| TN2809 |
22-Dehydroclerosterol |
22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori. |
| TN2820 |
24-Methylenecycloartan-3-ol |
24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli. |
| TN2849 |
3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid |
2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and a...
|
| TN2864 |
3',4',5',3,5,6,7-Heptamethoxyflavone |
|
| TN2866 |
3,4,5-Trimethoxycinnamyl alcohol |
3,4,5-Trimethoxycinnamyl alcohol shows significant antimicrobial and cytotoxic activities. |
| TN2867 |
3,4,5-Trimethoxyphenyl-(6-O-galloyl)-O-beta-D-glucopyranoside |
3,4,5-Trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside shows in vitro antiplasmodial activity. |
| TN2876 |
3,4-Dihydroxy-2-methoxyxanthone |
3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell...
|
| TN2898 |
3,5-Dihydroxy-4',7-dimethoxyflavone |
3,5-Dihydroxy-4',7-dimethoxyflavone shows antioxidant activity, it also shows significant activity against Staphylococcus aureus and Escherichia coli with minim...
|
| TN2931 |
3-Epikatonic acid |
Epikatonic acid shows less active against T. (S.) cruzi trypanosome. |
| TN2977 |
3-O-trans-p-Coumaroyltormentic acid |
3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in...
|
| TN3013 |
4,5-Dimethoxycanthin-6-one |
4,5-Dimethoxycanthin-6-one has antibacterial actiyity, it exhibits inhibition against Staphylococcus aureus and its drug-resistant strains. 4,5-Dimethoxycanthin...
|
| TN3027 |
4-Epialyxialactone |
4-Epialyxialactone exhibits significant antitumor and antibacterial activity. |
| TN3039 |
4-Hydroxyalternariol 9-methyl ether |
4-Hydroxyalternariol 9-methyl ether displays promising antioxidant effects. It also shows antibacterial activity against several tested bacterial pathogens with...
|
| TN3063 |
4-O-Methylsappanol |
4-O-Methylsappanol shows activity against this fungus against Beauveria bassiana. |
| TN3080 |
5,6,7-Trimethoxycoumarin |
5,6,7-Trimethoxycoumarin shows moderate inhibitory activity against Micrococcus luteus, it also displays an intermediate cytotoxic effects against brine shrimp ...
|
| TN3110 |
5-Geranoxy-7-methoxycoumarin |
5-Geranoxy-7-methoxycoumarin shows antifungal activity. |
| TN3112 |
5-Heneicosylresorcinol |
5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents triglyceride accumulation in 3T3-L1 cel...
|
| TN3116 |
5-Hydroxy-1-methoxyxanthone |
5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees ...
|
| TN3124 |
5-Hydroxysophoranone |
5-Hydroxysophoranone exhibits high antiplasmodial activity against Plasmodium falciparum (IC50=2.5 microg/mL). |
| TN3145 |
6,7-Dihydroneridienone A |
6,7-Dihydroneridienone A exhibits notable leishmanicidal activity. |
| TN3151 |
6-Acetonyl-N-methyl-dihydrodecarine |
6-Acetonyl- N -methyl-dihydrodecarine has mosquito larvicidal activity against the malaria vector Anopheles gambiae. |
| TN3160 |
6-Deoxyisojacareubin |
6-Deoxyisojacareubin shows moderate inhibitory activity against the QGY-7703 cell line, with the IC50 value of 9.65 uM; it also possesses potency in the inhibit...
|
| TN3161 |
6-Deoxyjacareubin |
6-Deoxyjacareubin possesses significant antioxidant activities, it also exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cel...
|
| TN3177 |
6-Methyl-5,6-dihydropyran-2-one |
6-Methyl-5,6-dihydropyran-2-on is bactericidal,and antiprotozoal agents. |
| TN3214 |
7,4'-Dihydroxy-3'-prenylflavan |
7,4'-Dihydroxy-3'-prenylflavan has antibacterial activity. |
| TN3220 |
7',8'-Dihydroobolactone |
7',8'-Dihydroobolactone can inhibit Trypanosoma brucei brucei with an IC(50) of 2.8 microM. |
| TN3221 |
7-Angeloylretronecine |
7-Angeloylretronecine may have antibacterial effects. |
| TN3260 |
8(14),15-Isopimaradien-3-ol |
ent-8(14),15-pimaradien-3beta-ol (8(14),15-Isopimaradien-3-ol) can induce vascular relaxation. It displays high antibacterial activities (MIC values lower than ...
|
| TN3276 |
8-Epixanthatin |
8-Epixanthatin, a light-induced growth inhibitor, mediates the phototropic curvature in sunflower (Helianthus annuus) hypocotyls, it can induce germination of O...
|
| TN3318 |
9-Hydroxy-alpha-lapachone |
9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, wit...
|
| TN3355 |
Agatharesinol acetonide |
Agatharesinol acetonide shows anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM). |
| TN3363 |
Agrimonolide 6-O-glucoside |
Agrimonolide-6-O-glucopyranoside has antimicrobial activity. |
| TN3397 |
Alpinumisoflavone |
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is ...
|
| TN3400 |
Altechromone A |
Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs ...
|
| TN3401 |
Altenuene |
Altenuene is a mycotoxin, it frequently occurs in food and feed items infested by fungi of the genus Alternaria. Altenuene demonstrates moderate activity agains...
|
| TN3404 |
Altholactone |
Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of...
|
| TN3409 |
Anagyrine |
Anagyrine, is the responsible teratogen from teratogenic lupins, can produce congenital deformities in calves typical of crooked calf disease; it also can induc...
|
| TN3422 |
Anisofolin A |
Anisofolin A has promising antimalarial activity (IC50 4.39 ± 0.25 uM). It has promising antimycobacterium activity [IC50 4.50 ± 0.75 uM (3.31 ug/mL)] against...
|
| TN3427 |
Aphadilactone B |
Aphadilactone B shows significant antimalarial activity with the IC50 value of 1350 ± 150 nM. |
| TN3438 |
Arborinine |
Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± ...
|
| TN3450 |
Artanin |
Artanin displays promising inhibition against both MSSA and MRSA with minimal inhibitory concentrations (MICs) of 8-64 ug/ml, but very weak against Gram-negativ...
|
| TN3452 |
Arteannuin M |
Arteannuin has antimalarial activity. It can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation. |
| TN3453 |
Arteannuin N |
Arteannuin has antimalarial activity. It can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation. |
| TN3456 |
Artoheterophyllin B |
Artoheterophyllin B has antiplasmodial activity. |
| TN3460 |
Asebogenin |
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, re...
|
| TN3465 |
Atalantoflavone |
Atalantoflavone shows urease inhibitory potential. It displays weak cytotoxic activity against the human Caucasian prostate adenocarcinoma cell line PC-3. |
| TN3490 |
Barbinervic acid |
Barbinervic acid shows anti-bacteria activity (IC50 = 0.098 g x LU(-1), IC50 = 0.27 g x L(-1)) against SA and ESBLs-SA respectively. |
| TN3495 |
Benzyl ferulate |
Benzyl ferulate has antimicrobial activity. It also shows good anti-proliferative against three gastro-intestinal cancer cell lines(HCT-116 colon carcinoma, KYS...
|
| TN3500 |
beta-Amyrone |
beta-Amyrone has antifungal activity, it also shows a moderate activity against Chikungunya virus replication (EC50 =86 uM). beta-Amyrone exhibits anti-α-gluco...
|
| TN3507 |
beta-Yohimbine |
Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor bloc...
|
| TN3528 |
Bonducellpin D |
Bonducellpin D may show inhibitory activities on the Para3 virus. It also exhibits moderate activity against four tested human cancer cell lines, HepG-2, K562, ...
|
| TN3540 |
Broussonin C |
Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase. |
| TN3547 |
Bullatantriol |
Bullatantriol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts. It may have weak antibacterial activities. |
| TN3549 |
Burchellin |
Burchellin has larvicidal activity, it can interfer with the development cycle of the mosquito, where its strongest toxic effect is 100% mortality in larvae (L3...
|
| TN3557 |
Cabraleadiol |
Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol...
|
| TN3560 |
Cabralealactone |
Cabralealactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line, it is moderate...
|
| TN3563 |
Caesalmin B |
Caesalmin B shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro. |
| TN3564 |
Caesalmin E |
Caesalmin E shows anti-Para3 virus activity. |
| TN3568 |
Calceolarioside A |
Calceolarioside A shows potent activity against visceral leishmaniasis. It can induce a dose-related aggregant effect on rabbit platelets, which may be partly r...
|
| TN3573 |
Camaric acid |
Camaric acid shows antibacterial activity against Staphylococcus aureus and methicillin resistant S. aureus with IC50 values 8.74 and 8.09 uM, respectively, it ...
|
| TN3580 |
Cannabispirol |
Cannabispirol has a weak antibacterial effect which is more definite on plasmid carrying bacteria than plasmidless ones, and inhibits intercellular plasmid tran...
|
| TN3583 |
Canophyllal |
Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs. |
| TN3584 |
Canthin-6-one N-oxide |
Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities. |
| TN3603 |
Carpinontriol B |
Carpinontriol B has antimicrobial activity, it at 40 ug/disk caused the formation of zones of inhibition. It also has anti-inflammatory activity, it shows consi...
|
| TN3616 |
Cedrelone |
Cedrelone exhibits antifeedant activity, it has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fa...
|
| TN3626 |
Cerbinal |
Cerbinal is a potent antifungal compound. |
| TN3627 |
Chalepensin |
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential ...
|
| TN3637 |
Chloramultilide B |
Chloramultilide B exhibits moderate in vitro antifungal activity. |
| TN3644 |
Chlorophorin |
Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values o...
|
| TN3650 |
Chrysothol |
Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity again...
|
| TN3670 |
Citromycin |
Citromycin, an antibiotic, has weakly cytotoxic. |
| TN3674 |
Clauszoline M |
Clauszoline M shows a significant anti-tuberculosis activity. |
| TN3680 |
Cleroindicin F |
Cleroindicin F shows cytotoxic activity against some human cancer cells. Cleroindicin F and apigenin in the ethyl acetate extract provide scientific support to ...
|
| TN3691 |
Communic acid |
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmeti...
|
| TN3699 |
Corchoionoside C |
Corchoionoside C has antioxidant activity, shows strong scavenging activities on DPPH radical, it also shows weak antifungal activity. Corchoionosides A, B, and...
|
| TN3707 |
Coronarin B |
Coronarin B has cytotoxic activity, it also has modest antiplasmodial activity. |
| TN3708 |
Coronarin D |
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentratio...
|
| TN3710 |
Coronarin E |
Coronarin E exhibits weak antimicrobial activity. |
| TN3713 |
Corymbosin |
Corymbosin shows significant antiviral activity. |
| TN3714 |
Corypalmine |
Corypalmine (IC50=128.0±10.5 uM) can inhibit prolyl oligopeptidase. (-)-Corypalmine shows inhibition activity against spore germination of some fungi. |
| TN3719 |
Cristacarpin |
Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-...
|
| TN3721 |
Cryptofolione |
Z-Cryptofolione and Cryptomoscatone D2 as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitors can force cells arrested in G(2) phas...
|
| TN3723 |
Cryptomeridiol |
Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low a...
|
| TN3729 |
Cuniloside B |
Cuniloside B shows anti-leishmanial activity. |
| TN3735 |
Cycloart-23-ene-3,25-diol |
Cycloart-23-ene-3,25-diol has anti-inflammatory activity, it has protective activity against streptozotocin induced toxicity. Cycloart-23-ene-3,25-diol treatmen...
|
| TN3747 |
Cynatratoside A |
Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against Ichthyophthirius multifiliis. |
| TMA0395 |
Danshenxinkun D |
Danshenxinkun D has antituberculosis H_(37)Rv activity in vitro. |
| TN3778 |
De-4'-O-methylyangambin |
De-4'-O-methylyangambin exhibits antibacterial effects. It also has analgesia activity. |
| TN3779 |
De-O-methyllasiodiplodin |
De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects on ...
|
| TN3790 |
Dehydroabietinol |
Dehydroabietinol inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro ...
|
| TN3797 |
Dehydrobruceine A |
Dehydrobruceine A shows strong antitrypanosomal activities with IC(50) values in the range of 2.9-17.8nM. |
| TN3799 |
Dehydrocrebanine |
Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an...
|
| TN3834 |
Derrone |
Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. It is also a novel Aurora kinase inhibitor, it ...
|
| TN3852 |
Dihydrolicoisoflavone |
Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infect...
|
| TN3861 |
Dihydropinosylvin |
Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penic...
|
| TN3896 |
Drimenol |
Drimenol shows antifungal activity, it is able to affect Botrytis cinerea growth with the EC50 value of 80 ppm. Drimendiol also shows quorum sensing inhibition ...
|
| TN3907 |
(E)-3-Hydroxy-5-methoxystilbene |
(E)-3-Hydroxy-5-methoxystilbene possesses inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus...
|
| TN3913 |
Echimidine |
Echimidine, a major hepatotoxic dehydropyrrolizidine alkaloid produced by E. plantagineum, in the honey (780 ng/g) and in the subsequent mead samples (236-540 n...
|
| TN3920 |
Effusanin A |
Effusanin A has antibacterial activity. It exhibits DNA-damaging activity in assay which employed DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) y...
|
| TN3921 |
Effusanin B |
Effusanin B shows antibacterial activity. It exhibits DNA-damaging activity in assay which employes DNA-repair deficient (RAD 52Y) and repair proficient (RAD +)...
|
| TN3922 |
Effusanin E |
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p...
|
| TN3943 |
ent-17-Hydroxykauran-3-one |
ent-17-Hydroxy-16α-kauran-3-one shows weak antimicrobial activity when tested against Staphylococcusaureus. |
| TN3978 |
Epitaraxerol |
Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. a...
|
| TMA1743 |
Ergosterol peroxide |
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fo...
|
| TN3987 |
Eriodictyol chalcone |
Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth. |
| TN3990 |
Erysenegalensein E |
Standard reference |
| TN3995 |
Erythrabyssin II |
Erythrabyssin II actives against several strains of Staphylococcus and Streptococcus with an MIC range of 0.78-1.56 microg/ml. It inhibits bacterial neuraminida...
|
| TN4010 |
Erythrocentaurin |
Erythrocentaurin has antibacterial activity; it also exhibits a concentration-dependent α-amylase inhibition (IC(50) 1.67 ± 0.28 mg/mL). |
| TN4014 |
Esculentoside B |
Phytolaccoside B(Esculentoside B) is an antifungal monodesmoside triterpenoid glycoside, it has potent inhibitory activity against agrobacterial plant transform...
|
| TN4023 |
Eucalyptin |
Eucalyptin has antioxidant and antimicrobial properties, it exhibits potent antimicrobial activities against seven micro-organisms with minimum inhibitory conce...
|
| TN4028 |
Euchrestaflavanone B |
Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavano...
|
| TN4040 |
Eupatoriochromene |
Eupatoriochromene retard seed germination , reduced radicle and hypocotyl growth of weed and crop plant seedlings and increased adventitious root formation of m...
|
| TN4045 |
Evofolin C |
Evofolin C and its acetate show strong antifungal and antibacterial activity. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine...
|
| TN4053 |
FD-838 |
FD-838 shows good antileishmanial and moderate anticancer activities, it can moderately inhibit the growth of cultured P388 and HL-60 cell lines. FD-838 has ant...
|
| TN4071 |
Formoxanthone A |
Formoxanthone A may have antibacterial and cytotoxic activities. |
| TN4084 |
Fumitremorgin B |
Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on t...
|
| TN4097 |
Gancaonin G |
Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptoc...
|
| TN4098 |
Gancaonin I |
Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM. |
| TN4108 |
Ganoderic acid Z |
The binding affinities of ganoderic acid DM and ganoderic acid Z (ÎGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug osel...
|
| TN4113 |
Garcinone E |
Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-res...
|
| TN4148 |
Glyasperin C |
Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candida...
|
| TN4159 |
Goniodiol |
(+)-Goniodiol and 7-epi-(+)-Goniodiol show high antibacterial activity (MIC, 3.1 mM) against Yersinia intermedia. |
| TN4167 |
Grifolic acid |
Grifolic acid is a natural carbonic anhydrase Ⅱ inhibitor(CAⅡ), it shows in-hibitory activities against CAⅡ with IC50 of 6.37 umol/L. Grifolic acid has an...
|
| TN4183 |
Hardwickiic acid |
Hardwickiic acid modulates hippocampal [(3)H]NA overflow evoked by a mild depolarizing stimulus by acting at presynaptic opioid receptor subtypes. Hardwickiic a...
|
| TN4202 |
(-)-Heraclenol |
(-)-Heraclenol shows in vitro anti-plasmodial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.(-)-Heraclenol h...
|
| TN4212 |
Hirsutanonol |
Hirsutanonol has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pe...
|
| TN4213 |
Hirsutenone |
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid per...
|
| TN4218 |
Homaloside D |
Homaloside D has antiplasmodial activity. |
| TN4223 |
Homopterocarpin |
Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric home...
|
| TN4227 |
Horminone |
Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi...
|
| TN4229 |
Humulene epoxide II |
Humulene epoxide II has antimalarial activity. |
| TN4234 |
Hydrangenol |
Hydrangenol is a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae), it can significantly inhibit the passive cutaneous anaphylaxis (PC...
|
| TN4261 |
Isoaltenuene |
Isoaltenuene shows antibiotic activity against Gram-positive bacteria; it also shows a minor phytotoxic activity on tomato leaves at level of 20 ug/spot . Isoal...
|
| TN4264 |
Isoapetalic acid |
Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell...
|
| TN4266 |
Isobonducellin |
Isobonducellin exhibits potent cytotoxic activity in Jurkat and HepG2 cells, while moderate growth inhibition against Colon205 cells. |
| TN4267 |
Isoboonein |
Isoboonein exhibits significant antitumor and antibacterial activity. |
| TN4271 |
Isochamaejasmine |
Isochamaejasmine has inhibition of NF-kappaB activation, which could reverse the anti-apoptotic effect; it induces apoptosis in leukemia cells by inhibiting the...
|
| TN4274 |
Isocostic acid |
Isocostic acid may have antibacterial activity. |
| TN4275 |
Isocudraniaxanthone A |
Isocudraniaxanthone A may have antimalarial activity. |
| TN4276 |
Isocudraniaxanthone B |
Isocudraniaxanthone B may have antimalarial activity. |
| TN4283 |
Isodiospyrin |
Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. Isodiospyrin has antibacterial activity, the mi...
|
| TN4288 |
Isoferulic acid |
Isoferulic acid is an effective natural antioxidant in both lipid and aqueous media, it may be a new promising anti-glycation agent for the prevention of diabet...
|
| TN4300 |
Isojacareubin |
Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the stand...
|
| TN4308 |
Isolupalbigenin |
Isolupalbigenin shows promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM), it also shows in vitro inhibitory activity toward huma...
|
| TN4314 |
Isonardoperoxide |
Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10-7 M). |
| TN4319 |
Isopimaric acid |
Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrati...
|
| TN4336 |
Isothymusin |
Isothymusin( MIC= 200 microg/mL) exhibits inhibition activity against Mycobacterium tuberculosis. It ( IC50=7.7 microg/mL ) exhibits antioxidant activity agains...
|
| TN4373 |
Kaempferol tetraacetate |
Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1. |
| TN4375 |
Kamebanin |
Kamebanin, a natural diterpenoid, has antibacterial activity. It also shows efficient cytotoxic activity against HeLa and HL-60 cells. |
| TN4387 |
Khellactone |
Khellactone shows antitumor activity,it can suppress the growth of NCI-H460 tumor cells. (+)-4'-cis-Khellactone and (+)-3'-cis-khellactone have antiplasmodial a...
|
| TN4388 |
Kielcorin |
Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolate...
|
| TN4399 |
Kushenol C |
Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2)...
|
| TN4402 |
Labd-13-ene-8,15-diol |
13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50)...
|
| TN4403 |
Lactupicrin |
Lactupicrin has antimicrobial and anti-cancer effects, it also protect the plant from insect feeding. |
| TN4420 |
Latifolin |
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Lati...
|
| TN4433 |
Licoarylcoumarin |
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE s...
|
| TN4443 |
Lipiferolide |
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibito...
|
| TN4449 |
Longistylin C |
Longistylin A and longistylin C show some cytotoxic effects, with IC(50) values of 0.7-14.7 microM against the range of cancer cell lines. Longistylin A and lon...
|
| TN4462 |
Lupeol caffeate |
Lupeol caffeate has anti-malarial activity. |
| TN4465 |
Luvangetin |
Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection again...
|
| TN4470 |
Lyoniside |
Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes, they demonstrate strong anti-leishmanial efficacies in BALB/c mice model ...
|
| TN4471 |
Lysicamine |
Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the rang...
|
| TN4473 |
Macrocarpal A |
Macrocarpal A is the key component that stimulates the synthesis of ceramide in the stratum corneum. Macrocarpal A has cytotoxic, and antibacterial activities. |
| TN4475 |
Macrocarpal C |
Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purifi...
|
| TN4476 |
Macrocarpal D |
Macrocarpal D is a HIV-RTase inhibitor. It has antibacterial activity. |
| TN4478 |
Macrocarpal H |
Macrocarpal H has anti-glucosyltransferase, and anti-bacterial activities. |
| TN4479 |
Macrocarpal I |
Macrocarpal I has anti-glucosyltransferase, and anti-bacterial activities. |
| TN4480 |
Macrocarpal J |
Macrocarpal J has anti-bacterial activity, it also has anti-glucosyltransferase activity. |
| TN4490 |
Manassantin B |
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti...
|
| TN4518 |
Meridinol |
Meridinol has wide antimicrobial activity, includes against gram-positive and gram-negative bacteria and fungi. |
| TN4530 |
Methyl 3-hydroxy-4,5-dimethoxybenzoate |
Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H2O2. It shows obvious antimicrobial activities, the mini...
|
| TN4531 |
Methyl 3-O-feruloylquinate |
Methyl 3-O-feruloylquinate inhibits the activity of bacteria and viruses and to regulate immunity. |
| TN4535 |
Methyl 6-acetoxyangolensate |
Methyl-6-acetoxy angolensate may have antimalarial activity. |
| TN4536 |
Methyl 6-hydroxyangolensate |
Methyl 6-hydroxyangolensate shows antifungal and antibacterial activities. |
| TN4551 |
Methyl orsellinate |
Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacu...
|
| TMA0394 |
Methyl tanshinonate |
Methyl tanshinonate has antioxidant activity, it can treat psoriasis. |
| TN4578 |
Monomethyl kolavate |
Monomethyl kolavate is a power Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) inhibitor, with an IC50 value of 12uM. |
| TN4579 |
Monomethylsulochrin |
Monomethylsulochrin shows antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. It shows moderat...
|
| TN4581 |
Moracin D |
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization ...
|
| TN4585 |
Moronic acid |
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186...
|
| TN4588 |
Mulberrofuran H |
Mulberrofuran H exhibits potent antifungal activity against phytopathogenic fungi Colletotrichum orbiculare, Phytophthora capsici, Corynespora cassiicola and Fu...
|
| TN4594 |
Murraol |
Murraol shows the significant proliferative activities on osteoblast-like UMR106 cells lines at the concentration of 1 × 10-10 mol/L. It and auraptenol show 63...
|
| TN4596 |
Musellactone |
Musellactone shows different effects against five bacteria strains. |
| TN4623 |
Nagilactone C |
Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vit...
|
| TN4634 |
Neocyclomorusin |
Neocyclomorusin displays minimal inhibitory concentration (MIC) value of 4 ug/mL against Klebsiella pneumoniae ATCC11296, Enterobacter cloacae BM47. |
| TN4648 |
Nepetoidin B |
Nepetoidin B has anti-fungal, anti-bacterial, and antiinflammatory effects, it can inhibit LPS-stimulated NO production possibly via modulation of iNOS mediated...
|
| TN4649 |
Neridienone B |
Neridienone B has significant effects on calcein accumulation. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana. |
| TN4650 |
Nervogenic acid |
Nervogenic acid has antioxidative, pro-coagulant, and antibacterial activities, it exhibits higher activity than that of t-butyl-4- hydroxyanisole (BHA) using t...
|
| TN4652 |
Niazimicin |
Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity i...
|
| TN4653 |
Niazinin |
Niazinin shows antileishmanial activity against promastigotes of Leishmania donavani, with an IC50 value of 5.25 microM. |
| TN4656 |
Nigracin |
|
| TN4660 |
Niranthin |
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competiti...
|
| TN4666 |
Norcaesalpinin E |
Norcaesalpinin E shows antimalarial activity against the malaria parasite Plasmodium falciparum FCR-3/A2 clone in vitro, with an IC50 value of 0.090 microM. |
| TN4670 |
Norlichexanthone |
Norlichexanthone has the potential to treat and/or prevent lifestyle-related diseases, including metabolic syndrome, type 2 diabetes, atherosclerosis and cardio...
|
| TN4673 |
(+)-Nortrachelogenin |
(+)-Nortrachelogenin is moderately active against HIV-1 in vitro; it also can induce morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 ...
|
| TN4675 |
Nortrachelogenin |
Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth...
|
| TN4683 |
Nyasol |
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory...
|
| TN4692 |
Octadecyl p-coumarate |
A mixture of (E)-octadecyl p-coumarate and (Z)-octadecyl p-coumarate has antifungal activity , it shows the dose dependent inhibition of the spore germination o...
|
| TN4696 |
Odorinol |
Odorine and odorinol inhibit both the initiation and promotion stages of two-stage skin carcinogenesis. (+)-Odorinol exhibits strong antiviral activity against ...
|
| TN4717 |
Oplopanone |
Oplopanone exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strain. |
| TN4725 |
Oxychelerythrine |
Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It ...
|
| TN4731 |
Pachyaximine A |
Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyr...
|
| TN4733 |
Pancixanthone A |
Pancixanthone A may have antimalarial activity, it also shows a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L...
|
| TN4742 |
Patulitrin |
Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammati...
|
| TN4748 |
Penduletin |
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendul...
|
| TN4760 |
Phaseollidin hydrate |
Phaseollidin hydrate shows less antifungal activity than the original phytoalexin phaseollidin. |
| TN4776 |
Physalin D |
Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 ...
|
| TN4778 |
Physalin H |
Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR indu...
|
| TN4797 |
Piperolactam C |
Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides. |
| TN4804 |
Platycoside A |
Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It ind...
|
| TN4808 |
Platyphyllenone |
Platyphyllenone has shown promising anti-filarial activity both in vitro and in vivo studies. It can inhibit the biosynthesis of violacein in C. violaceum CV026...
|
| TN4822 |
Prehelminthosporol |
Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facil...
|
| TN4834 |
Protoplumericin A |
Protoplumericin A displays distinct activity against some pathogenic bacteria and fungi. |
| TN4838 |
Pseurotin A |
Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteri...
|
| TN4851 |
Pterodondiol |
Pterodondiol has moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus ...
|
| TN4852 |
Pterodontic acid |
Pterodontic acid and pterodondiol showed moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis. |
| TN4871 |
Pyrolin |
Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola. |
| TN4906 |
Rengynic acid |
Rengynic acid has potent antiviral effect on RSV for the first time in vitro. |
| TN4927 |
Rupesin E |
Rupesin E shows significant antibacterial activities against Escherichia coli. |
| TN4932 |
Sageone |
Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gas...
|
| TN4933 |
Sahandol |
Sahandol shows antiprotozoal activity against P. falciparum and T. brucei rhodesiense. |
| TN4953 |
Sativan |
Sativan possesses a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi, it exhibits antituberculosis activity against Mycobacte...
|
| TN4968 |
Scopoline |
Scopoline, tropinol, ecgonine, and granatoline derivatives are therapeutic agents of the pyrrole and pyridine group. Scopoline has fungitoxic effects, it is inh...
|
| TN4990 |
Seneganolide |
Seneganolide has insect antifeeding activity. Seneganolide A has antifungal activity. |
| TN5012 |
Shizukaol C |
1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxici...
|
| TN5014 |
Shoreic acid |
Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, res...
|
| TMA0017 |
Sideroxylin |
Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus...
|
| TN5020 |
(+/-)-Sigmoidin A |
Sigmoidin A has moderate antioxidant, antimicrobial and anti-inflammatory activity. |
| TN5021 |
Sikokianin C |
Sikokianin C shows antimalarial activity against the chloroquine-resistant strain of Plasmodium falciparum, with the IC (50) value of 0.56 microg/mL. |
| TN5030 |
Sitoindoside I |
Sitoindoside I has anti-ulcerogenic activity. |
| TN5034 |
Beta-Solamarine |
Beta-Solamarine has antibacterial activity. |
| TN5039 |
Sorokinianin |
Sorokinianin is a phytotoxin, it has antifungal activity, it is highly effective in suppressing spore germination of F. solani (75%) at 100 ug/ml concentration. |
| TN5061 |
Stephanine |
l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of...
|
| TN5067 |
Stigmastane-3,5,6-triol |
Stigmastane-3,5,6-triol and derivatives could be used for preparing antiviral medicine. |
| TN5071 |
Stilbostemin N |
Stilbostemins N may exhibit moderate antibacterial activities. |
| TN5079 |
Sulochrin |
Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytoto...
|
| TN5082 |
Swietemahalactone |
Swietemahalactone exhibits antibacterial activity. |
| TN5091 |
Tagitinin A |
Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the ...
|
| TN5092 |
Tagitinin F |
Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes. |
| TN5117 |
Taxiphyllin |
Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity agains...
|
| TN5119 |
Taxoquinone |
Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important foo...
|
| TN5134 |
Tetrahydroxysqualene |
Tetrahdroxysqualene shows antimycobacterial activity with an MIC of 10.0 microg/mL, while showing only modest cytotoxicity. |
| TN5139 |
Thalifoline |
Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici. |
| TMA0955 |
Thunberginol C |
Thunberginol C exhibits antimicrobial activity against oral bacteria. It shows antiallergic activity in the in vitro bioassay using the Schults-Dale reaction in...
|
| TMA0507 |
Tomatidine |
Tomatidine shows antibiotic, and anti-inflammatory activities, it significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. Tomatid...
|
| TN5152 |
Topazolin |
Topazolin has weak fungitoxic activity, it displays significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 ug/mL, it...
|
| TN5173 |
Trichorabdal A |
Trichorabdal A shows a very strong in vitro antibacterial activity against Helicobacter pylori. |
| TN5190 |
Tryprostatin A |
Tryprostatin A is an inhibitor of breast cancer resistance protein. Tryprostatin A and tryprostatin B are indole alkaloid-based fungal products that inhibit mam...
|
| TN5201 |
Uncarinic acid E |
Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resu...
|
| TN5223 |
Vasicinolone |
Vasicinolone has anti-inflammatory, and antimicrobial activities. |
| TN5227 |
(+/-)-Vestitol |
Vestitol has antioxidation, anti-inflammatory and antimicrobial activities, it can strongly act in a low dose and concentration and have a promising potential t...
|
| TN5228 |
Vestitol |
Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil ...
|
| TN5229 |
Vibralactone B |
Vibralactone B shows antibacterial activity, it can inhibit significantly the growth of E. coli and Pseudomonas aeruginosa, with MBC values of 50 and 100 ug/mL,...
|
| TN5243 |
Vitexilactone |
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse tran...
|
| TN5245 |
Vitexolide D |
Vitexolide D shows moderate antibacterial activity against a panel of 46 Gram-positive strains. It also shows cytotoxic activities against the HCT-116 cancer ce...
|
| TN5254 |
Wighteone |
Wighteone is an antifungal isoflavone.Wighteone has in vitro cytocidal activity against KB cells, it has a potent anti-proliferative effect on human leukemia HL...
|
| TN5264 |
Xanthoxyletin |
Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory...
|
| TN5267 |
Yadanzioside I |
Yadanzioside I shows strong antiviral activity. |
| TN5278 |
Zederone |
Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads ...
|
| TN5279 |
Zeorin |
Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP2...
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