TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
|
TMA0291 |
Dehydroglyasperin D
|
517885-72-2
|
98%
|
|
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...
|
TN2995 |
4,10-Aromadendranediol
|
70051-38-6
|
98%
|
|
4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which may be beneficial to the treatm...
|
TN3319 |
9-Hydroxycanthin-6-one
|
138544-91-9
|
98%
|
|
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
|
TN4424 |
Lecanoric acid
|
480-56-8
|
98%
|
|
Lecanoric acid shows antioxidant activity with an IC50 value of 79-95 ug/ml, it at 100 ug/ml conc. shows high growth stimulating activity in terms of increased d...
|
T15204 |
EHT 1610
|
1425945-60-3
|
98%
|
|
EHT 1610 is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, r...
|
T21956 |
GSK3β inhibitor II
|
478482-75-6
|
98%
|
|
GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).
|
T22657 |
Laduviglusib trihydrochloride
|
1782235-14-6
|
98%
|
|
Laduviglusib trihydrochloride is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3α and GSK-3β. Laduviglusib trih...
|
T67856 |
WAY-333184
|
863004-48-2
|
98%
|
|
WAY-333184 is a weak GSK-3β inhibitor, IC50﹥ 100μM.
|
T6139 |
A-674563
|
552325-73-2
|
98%
|
|
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
|
T41094 |
Wnt/β-catenin agonist 2
|
943820-93-7
|
98%
|
|
Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist. Wnt/β-catenin agonist 2 can be used in the study of diseases related t...
|
T23601 |
ABC1183
|
1042735-18-1
|
98%
|
|
ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival b...
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
T64366 |
WAY-606956
|
|
98%
|
|
WAY-606956 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in Calipe Assay.
|
TN4637 |
Neogrifolin
|
23665-96-5
|
98%
|
|
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ...
|
T26894 |
BRD0209
|
1597439-87-6
|
98%
|
|
BRD0209 is a highly selective and potent GSK3 inhibitor.
|
T10786 |
Charantin
|
57126-62-2
|
98%
|
|
Charantin is a steroidal saponin isolated from Momordica charantia. It increases the release of insulin and slowing down gluconeogenesis. Charantin can inhibit G...
|
TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
T2310L |
CHIR-99021 HCl
|
1797989-42-4
|
98%
|
|
Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3α/β inhibitor with IC 50 s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows o...
|