T38665 |
OVA-E1 peptide TFA
|
1262750-80-0
|
|
|
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.
|
TN4394 |
Kobophenol A
|
124027-58-3
|
98%
|
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
|
TN4938 |
Samidin
|
477-33-8
|
98%
|
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
|
T78829 |
JNK2-IN-1
|
|
98%
|
|
JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 µM, exhibits anti-inflammatory effects by attenuating TNF-α and IL...
|
T79296 |
JNK-IN-12
|
|
98%
|
|
JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, comprising a mitochondrial-specific cell-penetrating peptide lin...
|
T79489 |
JNK-1-IN-2
|
|
98%
|
|
"JNK-1-IN-2 (Compound c6) is a potent inhibitor of JNK-1 with an IC50 of 33.5 nM, and also exhibits inhibitory effects on JNK-2 and JNK-3 with IC50 values of 112...
|
T79754 |
JNK-IN-14
|
|
98%
|
|
JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, 12.7 nM for JNK2, and 10.5 nM for JNK3. It induces early-stage apoptosis, arrests ce...
|
T80005 |
N-Butyl α-D-fructofuranoside
|
80971-59-1
|
98%
|
|
N-Butyl α-D-fructofuranoside, extracted from the root barks of Ulmus davidiana var. japonica, amplifies Nrf2 activity via JNK activation and exhibits anti-inflam...
|
T10937 |
D-JNKI-1
|
1445179-97-4
|
98%
|
|
D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.
|
TN4410 |
Lappaol C
|
64855-00-1
|
98%
|
|
Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also ...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
TN4877 |
Quercetin 3,4'-dimethyl ether
|
33429-83-3
|
98%
|
|
Quercetin 3,4'-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM), it also shows anti-inflammatory activity. Quercetin 3,4'-dimethyl ...
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
|
TN4317 |
Isopedicin
|
4431-42-9
|
98%
|
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
|
TN2511 |
Britannilactone diacetate
|
1286694-67-4
|
98%
|
|
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airwa...
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
TN4774 |
Physalin A
|
23027-91-0
|
98%
|
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
|
TN1775 |
Isocryptotanshinone
|
22550-15-8
|
98%
|
|
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative r...
|
TMA1743 |
Ergosterol peroxide
|
2061-64-5
|
98%
|
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
|
T72714 |
JNK3 inhibitor-3
|
2873465-25-7
|
98%
|
|
JNK3 Inhibitor-3 (compound 15g) is a selective, blood-brain barrier permeable, and orally active inhibitor of c-Jun N-terminal kinase 3 (JNK3) with IC50 values o...
|