Neurokinin B acetate(86933-75-7 free base) is the acetate form of Neurokinin B, which belongs to the tachykinin family. Neurokinin binds to neurokinin receptor 1 (NK1R), nk2r and NK3R, and mediates its biological effects.

LCB 03-0110 (3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol) is a potent inhibitor of discoidin domain receptor family tyrosine kinases and strongly inhibits several tyrosine kinases, including the c-Src family, spleen tyrosine kinase, Bruton's tyrosine kinase, and vascular endothelial growth factor receptor 2, which are important for immune cell signaling and inflammatory reactions.

3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 μM and an E.max value of > 250 μM for TREM2.

7-Xylosyl-10-deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative from the Northeastern red bean tree (Picea abies) in the Sequoia family, with antitumor activity, and can be used for the synthesis of paclitaxel.

7-Aminodeacetoxycephalosporanic acid (Cefalexine EP IMpurity B) is used as an antibiotic.

Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.

(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone featuring a complex bicyclic structure [1].

Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr.

5,6,7,4'-tetrahydroxyisoflavone-6,7-di-O-beta-D-glucopyranoside is a natural product

2,9-Dihydroxy-7-methoxy-4-methylnaphtho[1,2-b]fura is a useful organic compound for research related to life sciences. The catalog number is T125732 and the CAS number is 1558053-97-6.

2-Amino-4-chloro-N2-pivaloyl-7-[2-deoxy-3,5-di-O-(4- methylbenzoyl)-b-D-ribofuanosyl]-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deazapurine nucleoside; Halo-nucleoside.

2-Amino-4-chloro-5-iodo-N2-pivaloyl-7-[2-deoxy-3,5-di-O- (4-methylbenzoyl)-b-D-ribofuanosyl]-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deazapurine nucleoside; Halo-nucleoside.

Methyl 1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate is a useful organic compound for research related to life sciences and the catalog number is T67279.

(11aR)-5-(4,5,6,7-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine is a useful organic compound for research related to life sciences and the catalog number is T64513.

Lysobactin, also known as katanosin B, is an effective antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis.

7-Xylosyltaxol B is a natural product from Taxus wallichiana var.mairei.

HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.

(11AS)-5-(4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-yl)-5H-dibenzo[b,f]azepine is a useful organic compound for research related to life sciences and the catalog number is T64639.

Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s) of 6.7 nM and 5.2 nM, respectively [1].

4-Amino-6-bromo-5-cyano-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside, 8-Modified-purine nucleoside, Halo-nucleoside; Scaffold and Template.

4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template.

4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1024.

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1021.

7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-ribofuranosyl)guanine is a useful organic compound for research related to life sciences and the catalog number is TNU0394.

4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template.

3'-Methoxyapiin (Graveobioside B) is a flavonoid from the herbs of Eminium spiculatum.

B-Raf IN 7 (compound 6a) is a potent inhibitor of B-Raf with an IC 50 of 110.23 nM. B-Raf IN 7 has antitumor activity against colon carcinoma cells(HCT-116), mammary gland cells(MCF-7), hepatocellular carcinoma cells(HEPG-2), human cervical carcinoma cells(Hela) and human prostate cancer cells(PC-3). The IC50 values are 7.50, 9.87, 10.57, 11.63 and 12.83 μM, respectively [1].

CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.

4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - Halo-nucleoside, 7-Deaza-purine nucleoside.

Thieno[3,2-b]pyridin-7-ol has a wide range of applications in life science related research.

SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM). SN-38 has antitumor activity and induces autophagy.

4-Chloro-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]-pyrimidine is a Nucleoside Derivative - Halo-nucleoside, 7-Deaza-purine nucleoside.

4-Amino-1-(2-b-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside.

Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.

MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor. MAO-B-IN-7 exhibits IC50 s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 effectively alleviates oxidative stress and neuroinflammatory damage.

Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).

4-Amino-5-cyano-1-(2-b-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside.

1-Cyclopropyl-6,8-difluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66337 and the CAS number is 151213-15-9.

(15aR)-1,15-Bis(diphenylphosphino)-7,8,9,10-tetrahydro-6H-dibenzo[b,d][1,6]dioxacycloundecine is a useful organic compound for research related to life sciences and the catalog number is T67391.

Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosides

Nucleoside Derivatives - 7-Deaza-purine nucleosides; Natural product; inhibitor of protein kinase C

Nucleoside Derivatives - 7-Deaza-purine nucleosides; 6-De-aminopurine nucleosides

Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides

[MePhe7]-Neurokinin B is a neurokinin NK-3 receptor (NK3R) agonist, exhibiting a potent agonistic activity with an IC50 value of 3 nM. It acts as a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion through the activation of NK3R [1].

7β-Hydroxycucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5978 and the CAS number is 1135141-79-5.

7,8,9-Trimethoxy-10H-1,3-dioxolo[4,5-b]xanthen-10-one is a useful organic compound for research related to life sciences and the catalog number is T125216.

4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1039.

(6bR,10aS)-Ethyl 3-methyl-2,3,6b,7,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(9H)-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T67021 and the CAS number is 313369-26-5.