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Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.
Cat. No. Product name CAS No. Purity Chemical Structure
T4571 Balsalazide 80573-04-2 98%
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
T36526 IL-17 modulator 4 2446803-65-0 98%
IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.
T10389 Aspartyl-alanyl-diketopiperazine 110954-19-3 98%
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin.
TN4379 Kansuinine A 57701-86-7 98%
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
T0054 Disulfiram 97-77-8
Disulfiram is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the interme...
T13375 YQ128 2454246-18-3
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T9913 Ustekinumab 815610-63-0
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
T9911 Tocilizumab 375823-41-9
Tocilizumab anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
T8033 Sodium Thiocyanate 540-72-7
Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.
TQ0181 Resatorvid 243984-11-4 100%
Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 n...
T0304 Methylthiouracil 56-04-2 100%
Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
T6S2140 β-Anhydroicaritin 38226-86-7 96.95%
1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover...
T8867 RO2959 Hydrochloride 1219927-22-6 97.42%
RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T2061 APY0201 1232221-74-7 98%
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
T6761 Ossirene 106566-58-9 98%
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
T5641 RP-54745 135330-08-4 98%
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
T1273 Diacerein 13739-02-1 98.14%
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is res...
TN1291 7,3',4'-Tri-O-methylluteolin 29080-58-8 98.66%
5-Hydroxy-3',4',7-trimethoxyflavone has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC val...
T4602 Hydrocortisone hemisuccinate 2203-97-6 98.7%
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
T14778 BRD6989 642008-81-9 98.82%
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
Balsalazide
T4571
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
IL-17 modulator 4
T36526
IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.
Aspartyl-alanyl-diketopiperazine
T10389
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin.
Kansuinine A
TN4379
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
Disulfiram
T0054
Disulfiram is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the interme...
YQ128
T13375
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
Ustekinumab
T9913
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
Tocilizumab
T9911
Tocilizumab anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
Sodium Thiocyanate
T8033
Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.
Resatorvid
TQ0181
Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 n...
Methylthiouracil
T0304
Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
β-Anhydroicaritin
T6S2140
1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover...
RO2959 Hydrochloride
T8867
RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
APY0201
T2061
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
Ossirene
T6761
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
RP-54745
T5641
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
Diacerein
T1273
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is res...
7,3',4'-Tri-O-methylluteolin
TN1291
5-Hydroxy-3',4',7-trimethoxyflavone has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC val...
Hydrocortisone hemisuccinate
T4602
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
BRD6989
T14778
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
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