Home Tools
Log in
Cart

Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.
Cat No. product name
T2018 Apilimod Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.
T5641 RP-54745 RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
T2S0843 Negletein 1. Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action...
T1846 Y-320 Y-320 is a new phenylpyrazoleanilide immunomodulator.
T6761 Ossirene AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
T0304 Methylthiouracil Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
T2791 Pectolinarin Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T5359 RCGD423 RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair.
T2601 Vidofludimus Vidofludimus (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T1273 Diacerein Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is res...
T0117 Suplatast (Tosilate) Suplatast Tosilate is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
T2S0342 Armillarisin A Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
T2720 Ginsenoside Rc Ginsenoside Rc is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
T1813 VGX-1027 VGX-1027(GIT27) is an isoxazole compound with various immunomodulatory properties.
T9157 GP130 receptor agonist-1 N-(4-Fluorophenyl)-4-phenyl-2-thiazolami is a potent, brain-penetrant and orally active GP130 receptor agonist.
T2893 Muscone Muscone is an organic compound that is the primary contributor to the odor of musk.
T9911 Tocilizumab Tocilizumab anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
T9913 Ustekinumab Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
T6S1538 Neochlorogenic acid (E)-Neochlorogenic Acid is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
T2932 Ginsenoside Rh1 Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T3571 SU5201 NSC 247030 is a biochemical.
T3533 Apilimod mesylate Apilimod mesylate is a potent IL-12/IL-23 inhibitor.
T4602 Hydrocortisone hemisuccinate Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
T6S2140 β-Anhydroicaritin 1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover...
TN1291 7,3',4'-Tri-O-methylluteolin 5-Hydroxy-3',4',7-trimethoxyflavone has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC val...
T2061 APY0201 APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
TQ0181 Resatorvid Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 n...
T14778 BRD6989 BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
T3829 Ginsenoside F3 Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhan...
T3133 YM-90709 YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
T13375 YQ128 YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T4450 GIBH-130 GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
T0054 Disulfiram Disulfiram is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the interme...
T6207 SC144 SC144 is an orally active small-molecule gp130 inhibitor.
T6S1597 Mulberroside A 1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
T4403 AX-024 hydrochloride AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interfer...
T4571 Balsalazide Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
T8867 RO2959 Hydrochloride RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T11634 IL-15-IN-1 IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
T4615 Balsalazide sodium hydrate Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing pr...
T14687 Deucravacitinib BMS-986165 inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of ...
T8280 Deacetylasperulosidic Acid Deacetylasperulosidic acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also pr...
TN4379 Kansuinine A Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
T10389 Aspartyl-alanyl-diketopiperazine Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin.
T7649 Tyrphostin A1 Tyrphostin A1 is an inhibitor of EGFR tyrosine kinase .
T2758 Madecassic acid Madecassic acid is extracted from the whole herb of Centella asiatica.
Apilimod
T2018
Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.
RP-54745
T5641
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
Negletein
T2S0843
1. Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the acti...
Y-320
T1846
Y-320 is a new phenylpyrazoleanilide immunomodulator.
Ossirene
T6761
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
Methylthiouracil
T0304
Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
Pectolinarin
T2791
Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
RCGD423
T5359
RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair.
Vidofludimus
T2601
Vidofludimus (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
Diacerein
T1273
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is res...
Suplatast (Tosilate)
T0117
Suplatast Tosilate is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
Armillarisin A
T2S0342
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
Ginsenoside Rc
T2720
Ginsenoside Rc is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
VGX-1027
T1813
VGX-1027(GIT27) is an isoxazole compound with various immunomodulatory properties.
GP130 receptor agonist-1
T9157
N-(4-Fluorophenyl)-4-phenyl-2-thiazolami is a potent, brain-penetrant and orally active GP130 receptor agonist.
Muscone
T2893
Muscone is an organic compound that is the primary contributor to the odor of musk.
Tocilizumab
T9911
Tocilizumab anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
Ustekinumab
T9913
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
Neochlorogenic acid
T6S1538
(E)-Neochlorogenic Acid is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
Ginsenoside Rh1
T2932
Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
SU5201
T3571
NSC 247030 is a biochemical.
Apilimod mesylate
T3533
Apilimod mesylate is a potent IL-12/IL-23 inhibitor.
Hydrocortisone hemisuccinate
T4602
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
β-Anhydroicaritin
T6S2140
1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover...
7,3',4'-Tri-O-methylluteolin
TN1291
5-Hydroxy-3',4',7-trimethoxyflavone has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC val...
APY0201
T2061
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
Resatorvid
TQ0181
Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 n...
BRD6989
T14778
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant C...
Ginsenoside F3
T3829
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhan...
YM-90709
T3133
YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
YQ128
T13375
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
GIBH-130
T4450
GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
Disulfiram
T0054
Disulfiram is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the interme...
SC144
T6207
SC144 is an orally active small-molecule gp130 inhibitor.
Mulberroside A
T6S1597
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
AX-024 hydrochloride
T4403
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interf...
Balsalazide
T4571
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
RO2959 Hydrochloride
T8867
RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
IL-15-IN-1
T11634
IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
Balsalazide sodium hydrate
T4615
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing pr...
Deucravacitinib
T14687
BMS-986165 inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of ...
Deacetylasperulosidic Acid
T8280
Deacetylasperulosidic acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also pr...
Kansuinine A
TN4379
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
Aspartyl-alanyl-diketopiperazine
T10389
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin.
Tyrphostin A1
T7649
Tyrphostin A1 is an inhibitor of EGFR tyrosine kinase .
Madecassic acid
T2758
Madecassic acid is extracted from the whole herb of Centella asiatica.