T1839 |
Mps1-IN-2 |
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor. |
T2039 |
GSK923295 |
GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM). |
T2313 |
MPI0479605 |
MPI-0479605 is an ATP competitive and selective inhibitor. |
T2689 |
AZ 3146 |
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM. |
T3118 |
Dimethylenastron |
Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner. |
T3120 |
K858 |
K858 is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner. |
T4048 |
Monastrol |
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5. |
T6393 |
ARQ 621 |
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1. |
T4649 |
Monastrol |
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM. |
TQ0314 |
EMD534085 |
EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM). |
T12434 |
PF-2771 |
PF-2771 is an inhibitor of centromere protein E (CENP-E)(IC50 of 16.1 nM). |
T8487 |
Empesertib |
Empesertib is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity. |
T14765 |
BOS-172722 |
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint. With an IC50 of 2 nM. |
T14906 |
CCT251455 |
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM). |
T11155 |
Eg5 Inhibitor V, trans-24 |
Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 agonist inhibitor that can be used in cancer research with an IC50 value of 0.65 uM. |
T11859L |
Litronesib |
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity. |
T16152 |
Betamethasone 17-benzoate |
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU). |
T17007 |
TC-Mps1-12 |
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) . |