Kinesin

A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments, and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport.

Cat. No.	Product name	CAS No.	Purity
T4649	Monastrol	254753-54-3	98%
T4649	Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T16152	Betamethasone 17-benzoate	22298-29-9	98%
T16152	Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
T11859L	Litronesib	910634-41-2	98%
T11859L	Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
T12434	PF-2771	2070009-55-9	98%
T12434	PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor activity with an IC 50 of 16.1 nM. PF-2771 is used as an...
T3434	BAY1217389	1554458-53-5	98%
T3434	BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
TQ0314	EMD534085	858668-07-2	98%
TQ0314	EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
T14906	CCT251455	1400284-80-1	98%
T14906	CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
T17007	TC-Mps1-12	1206170-62-8	98%
T17007	TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
T22289	CFI-402257	1610759-22-2	98%
T22289	CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.
T12237	NMS-P715	1202055-32-0	98%
T12237	NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
T3118	Dimethylenastron	863774-58-7	85.65%
T3118	Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
T36816	S-trityl-L-Cysteine	2799-07-7	97.02%
T36816	S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. ...
T8342	BRD9876	32703-82-5	97.22%
T8342	BRD9876 is a selective inhibitor of MM1S growth.
T8487	Empesertib	1443763-60-7	97.45%
T8487	Empesertib is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
T11155	Eg5 Inhibitor V, trans-24	869304-55-2	97.45%
T11155	Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
T2255	SB-743921 hydrochloride	940929-33-9	98%
T2255	SB-743921 is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).
T2689	AZ3146	1124329-14-1	98.03%
T2689	AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
T6393	ARQ 621	1095253-39-6	98.38%
T6393	ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
T6209	CW-069	1594094-64-0	98.59%
T6209	CW069( IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
T4048	Monastrol	329689-23-8	99.19%
T4048	Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.