T78125 |
PVZB1194
|
1141768-04-8
|
98%
|
|
PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inh...
|
T16152 |
Betamethasone 17-benzoate
|
22298-29-9
|
98%
|
|
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
|
TQ0314 |
EMD534085
|
858668-07-2
|
98%
|
|
EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
|
T9207 |
GW406108X
|
1644443-92-4
|
98%
|
|
GW406108X (GW108X) is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) a...
|
T14906 |
CCT251455
|
1400284-80-1
|
98%
|
|
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
|
T28848 |
SR31527
|
311814-78-5
|
98%
|
|
SR31527 (SR31527 chloride) is a potent KIFC1 inhibitor with an IC50 of 6.6 µM against KIFC1. SR31527 chloride has a moderate inhibitory effect on cell viability ...
|
T11859L |
Litronesib
|
910634-41-2
|
98%
|
|
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
|
T12434 |
PF-2771
|
2070009-55-9
|
98%
|
|
PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor activity with an IC 50 of 16.1 nM. PF-2771 is used as an...
|
T4649 |
(S)-Monastrol
|
254753-54-3
|
98%
|
|
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
|
T17007 |
TC-Mps1-12
|
1206170-62-8
|
98%
|
|
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
|
T9682 |
AZD-4877
|
758722-49-5
|
99.87%
|
|
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, ind...
|
T16130 |
Mps1-IN-3
|
1609584-72-6
|
99.85%
|
|
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
|
T29059 |
UMK57
|
342595-74-8
|
99.81%
|
|
UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds, an...
|
T14765 |
BOS-172722
|
1578245-44-9
|
99.79%
|
|
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).
|
T9207L |
GW406108X(Z/E)
|
265098-01-9
|
99.71%
|
|
GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .
|
T2039 |
GSK-923295
|
1088965-37-0
|
99.71%
|
|
GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).
|
T12359 |
Paprotrain
|
57046-73-8
|
99.69%
|
|
Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
|
T2103 |
Ispinesib
|
336113-53-2
|
99.57%
|
|
Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic prope...
|
T3434 |
BAY1217389
|
1554458-53-5
|
99.54%
|
|
BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
|
T3120 |
K858 (Racemic)
|
72926-24-0
|
99.5%
|
|
K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.
|