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Endocrinology/Hormones Reductase

Reductase

Reductase is an enzyme that catalyzes a reduction reaction.
Cat No. Product Name
T0488 Finasteride Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T0725 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T1076 DexamethasoneHOT Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.
T1458 Epalrestat Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy ...
T1499 Dutasteride Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
T2013 Ponalrestat Ponalrestat is an aldose reductase inhibitor.
T3665 Tectoridin Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflam...
T3915 Ginsenoside Ro GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
T6S0840 Engeletin 1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engel...
T6102 2'-acetylacteoside 2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-A...
T6S2384 Poliumoside Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exh...
T5195 Alrestatin Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
T4918 DL-Glyceraldehyde Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When ...
T5813 BYAKANGELICIN BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataract...
TN2295 Vicenin -1 Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
T10393 AT-007 AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and pre...
T15281 Fidarestat Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the poten...
T17114 Tolrestat Tolrestat is a potent and orally active inhibitor of aldose reductase (IC50: 35 nM).
Finasteride
T0488CAS 98319-26-7
Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
Isoliquiritigenin
T0725CAS 961-29-5
Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
Dexamethasone HOT
T1076CAS 50-02-2
Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.
Epalrestat
T1458CAS 82159-09-9
Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy ...
Dutasteride
T1499CAS 164656-23-9
Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
Ponalrestat
T2013CAS 72702-95-5
Ponalrestat is an aldose reductase inhibitor.
Tectoridin
T3665CAS 611-40-5
Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflam...
Ginsenoside Ro
T3915CAS 34367-04-9
GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
Engeletin
T6S0840CAS 572-31-6
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engel...
2'-acetylacteoside
T6102CAS 94492-24-7
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-A...
Poliumoside
T6S2384CAS 94079-81-9
Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exh...
Alrestatin
T5195CAS 51411-04-2
Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
DL-Glyceraldehyde
T4918CAS 56-82-6
Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When ...
BYAKANGELICIN
T5813CAS 482-25-7
BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataract...
Vicenin -1
TN2295CAS 35927-38-9
Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
AT-007
T10393CAS 2170729-29-8
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and pre...
Fidarestat
T15281CAS 136087-85-9
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the poten...
Tolrestat
T17114CAS 82964-04-3
Tolrestat is a potent and orally active inhibitor of aldose reductase (IC50: 35 nM).