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Reductase

T0488	Finasteride	Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T0725	Isoliquiritigenin	Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T1076	Dexamethasone	Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.
T1458	Epalrestat	Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy ...
T1499	Dutasteride	Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
T2013	Ponalrestat	Ponalrestat is an aldose reductase inhibitor.
T3665	Tectoridin	Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflam...
T3915	Ginsenoside Ro	GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
T6S0840	Engeletin	1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engel...
T6102	2'-acetylacteoside	2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-A...
T6S2384	Poliumoside	Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exh...
T5195	Alrestatin	Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
T4918	DL-Glyceraldehyde	Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When ...
T5813	BYAKANGELICIN	BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataract...

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