Reductase

Reductase is an enzyme that catalyzes a reduction reaction.

Cat No.	product name
T1499	Dutasteride	Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
T3665	Tectoridin	Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
T0725	Isoliquiritigenin	Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T14175	Aldose reductase-IN-1	Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).
T35317	Zopolrestat	Zopolrestat is an aldose reductase inhibitor that may be used in the treatment of diabetic nephropathy and diabetes.
T3378	Alpha-Estradiol	Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).
T23403	Sulindac sulfone	Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.
T3915	Ginsenoside Ro	GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
TN1661	Ganoderic acid C2	Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on t...
T6S0840	Engeletin	1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engelet...
T15568	Imirestat	Imirestat is an aldose reductase inhibitor. It is used for the treatment of diabetes.
T5S0543	Isocurcumenol	1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
T2013	Ponalrestat	Ponalrestat is an aldose reductase inhibitor.
T22757	EBPC	EBPC is an inhibitor of aldose reductase.
TN2601	12-O-Methylcarnosic acid	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibitio...
TN2295	Vicenin-1	Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
T6S2384	Poliumoside	Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhib...
T7478	2-Chloro-1-(4-fluorobenzyl)benzimidazole	2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
T0488	Finasteride	Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T10393	AT-007	AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
TN3287	8-Lavandulylkaempferol	8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
TN3760	Danshenol A	Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
T4918	DL-Glyceraldehyde	Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When p...
T5813	BYAKANGELICIN	BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts...
T5015	Gonadorelin Acetate (33515-09-2 free base)	Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
T5195	Alrestatin	Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
T6102	2'-acetylacteoside	2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ace...
T15281	Fidarestat	Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potentia...
T1458	Epalrestat	Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
T17114	Tolrestat	Tolrestat 是一种有效的醛糖还原酶抑制剂 (IC50 = 35 nM)。
T16910	Sorbinil	Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...