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Reductase

Reductase is an enzyme that catalyzes a reduction reaction.
Cat No. product name
T1499 Dutasteride Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
T3665 Tectoridin Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
T0725 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T14175 Aldose reductase-IN-1 Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).
T35317 Zopolrestat Zopolrestat is an aldose reductase inhibitor that may be used in the treatment of diabetic nephropathy and diabetes.
T3378 Alpha-Estradiol Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).
T23403 Sulindac sulfone Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.
T3915 Ginsenoside Ro GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
TN1661 Ganoderic acid C2 Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on t...
T6S0840 Engeletin 1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engelet...
T15568 Imirestat Imirestat is an aldose reductase inhibitor. It is used for the treatment of diabetes.
T5S0543 Isocurcumenol 1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
T2013 Ponalrestat Ponalrestat is an aldose reductase inhibitor.
T22757 EBPC EBPC is an inhibitor of aldose reductase.
TN2601 12-O-Methylcarnosic acid 12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibitio...
TN2295 Vicenin-1 Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
T6S2384 Poliumoside Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhib...
T7478 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
T0488 Finasteride Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T10393 AT-007 AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
TN3287 8-Lavandulylkaempferol 8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
TN3760 Danshenol A Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
T4918 DL-Glyceraldehyde Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When p...
T5813 BYAKANGELICIN BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts...
T5015 Gonadorelin Acetate (33515-09-2 free base) Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
T5195 Alrestatin Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
T6102 2'-acetylacteoside 2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ace...
T15281 Fidarestat Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potentia...
T1458 Epalrestat Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
T17114 Tolrestat Tolrestat 是一种有效的醛糖还原酶抑制剂 (IC50 = 35 nM)。
T16910 Sorbinil Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
Dutasteride
T1499
Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
Tectoridin
T3665
Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
Isoliquiritigenin
T0725
Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
Aldose reductase-IN-1
T14175
Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).
Zopolrestat
T35317
Zopolrestat is an aldose reductase inhibitor that may be used in the treatment of diabetic nephropathy and diabetes.
Alpha-Estradiol
T3378
Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).
Sulindac sulfone
T23403
Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.
Ginsenoside Ro
T3915
GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
Ganoderic acid C2
TN1661
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on t...
Engeletin
T6S0840
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engele...
Imirestat
T15568
Imirestat is an aldose reductase inhibitor. It is used for the treatment of diabetes.
Isocurcumenol
T5S0543
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
Ponalrestat
T2013
Ponalrestat is an aldose reductase inhibitor.
EBPC
T22757
EBPC is an inhibitor of aldose reductase.
12-O-Methylcarnosic acid
TN2601
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibiti...
Vicenin-1
TN2295
Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
Poliumoside
T6S2384
Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhi...
2-Chloro-1-(4-fluorobenzyl)benzimidazole
T7478
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
Finasteride
T0488
Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
AT-007
T10393
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
8-Lavandulylkaempferol
TN3287
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
Danshenol A
TN3760
Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
DL-Glyceraldehyde
T4918
Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When p...
BYAKANGELICIN
T5813
BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts...
Gonadorelin Acetate (33515-09-2 free base)
T5015
Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
Alrestatin
T5195
Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
2'-acetylacteoside
T6102
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ac...
Fidarestat
T15281
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potent...
Epalrestat
T1458
Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
Tolrestat
T17114
Tolrestat 是一种有效的醛糖还原酶抑制剂 (IC50 = 35 nM)。
Sorbinil
T16910
Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...