T11231 |
ERRγ Inverse Agonist 1
|
2316832-86-5
|
98%
|
|
ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist (IC 50=40 nM) [1].
|
T11222 |
ERB-196
|
550997-55-2
|
98%
|
|
Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.
|
T0171 |
Norethynodrel
|
68-23-5
|
98%
|
|
Norethynodrel is a synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uteri...
|
TN1679 |
Genistein 7,4'-di-O-β-D-glucoside
|
36190-98-4
|
98%
|
|
Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.
|
T12312 |
OP-1074
|
1443752-76-8
|
98%
|
|
OP-1074 is a pure antiestrogen and a selective degrader of ER, shows specific antiestrogenic activity for ERα and ERβ.
|
T12329 |
Ospemifene D4
|
T12329
|
98%
|
|
Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor.
|
T16351 |
NSC16168
|
6837-93-0
|
98%
|
|
NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer. NSC16168 is a specific ERCC1-XPF inhibitor (IC50: 0.42 μM).
|
TQ0163 |
Sagittatoside A
|
118525-35-2
|
98%
|
|
Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα.
|
TN1690 |
Glabrene
|
60008-03-9
|
98%
|
|
Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
|
T6827 |
Endoxifen Z-isomer hydrochloride
|
1032008-74-4
|
98%
|
|
Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
|
TN2200 |
Segetalin A
|
161875-97-4
|
98%
|
|
Segetalin A has estrogen-like activity.
|
T12278 |
NXT629
|
1454925-59-7
|
98%
|
|
NXT629 is a selective and competitive antagonist of PPAR-α(human PPARα with an IC50 of 77 nM).
|
T6404 |
Bazedoxifene hydrochloride
|
198480-56-7
|
98%
|
|
Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectivel...
|
TN2288 |
Uralenol
|
139163-15-8
|
98%
|
|
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
|
TQ0149 |
Prinaberel
|
524684-52-4
|
98%
|
|
Prinaberel (ERB-041) is an effective and selective ERβ agonist and >200-fold selective for ERβ.
|
TN2045 |
Pelargonidin-3-O-glucoside chloride
|
18466-51-8
|
98%
|
|
Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflam...
|
T3645 |
Endoxifen E-isomer hydrochloride
|
1197194-61-8
|
98%
|
|
Endoxifen, a tamoxifen metabolite, is effective specific Estrogen Response Modifier (SERM).
|
T20720 |
Norethisterone enanthate
|
3836-23-5
|
98%
|
|
Norethindrone enanthate has antigonadotropic effects and can be used as a hormonal contraceptive. It is also a useful compound to study chem.-chem. interaction f...
|
T11230 |
ERRα antagonist-1
|
1072145-33-5
|
98%
|
|
ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferato...
|
T1579 |
Mestranol
|
72-33-3
|
98%
|
|
Mestranol, a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.
|