Estrogen/progestogen Receptor

Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol). Two classes of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and GPER (GPR30), which is a member of the rhodopsin-like family of G protein-coupled receptors.The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone.

Cat. No.	Product name	CAS No.	Purity
T11231	ERRγ Inverse Agonist 1	2316832-86-5	98%
T11231	ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist (IC 50=40 nM) [1].
T11222	ERB-196	550997-55-2	98%
T11222	Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.
T0171	Norethynodrel	68-23-5	98%
T0171	Norethynodrel is a synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uteri...
TN1679	Genistein 7,4'-di-O-β-D-glucoside	36190-98-4	98%
TN1679	Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.
T12312	OP-1074	1443752-76-8	98%
T12312	OP-1074 is a pure antiestrogen and a selective degrader of ER, shows specific antiestrogenic activity for ERα and ERβ.
T12329	Ospemifene D4	T12329	98%
T12329	Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor.
T16351	NSC16168	6837-93-0	98%
T16351	NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer. NSC16168 is a specific ERCC1-XPF inhibitor (IC50: 0.42 μM).
TQ0163	Sagittatoside A	118525-35-2	98%
TQ0163	Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα.
TN1690	Glabrene	60008-03-9	98%
TN1690	Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
T6827	Endoxifen Z-isomer hydrochloride	1032008-74-4	98%
T6827	Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
TN2200	Segetalin A	161875-97-4	98%
TN2200	Segetalin A has estrogen-like activity.
T12278	NXT629	1454925-59-7	98%
T12278	NXT629 is a selective and competitive antagonist of PPAR-α(human PPARα with an IC50 of 77 nM).
T6404	Bazedoxifene hydrochloride	198480-56-7	98%
T6404	Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectivel...
TN2288	Uralenol	139163-15-8	98%
TN2288	Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
TQ0149	Prinaberel	524684-52-4	98%
TQ0149	Prinaberel (ERB-041) is an effective and selective ERβ agonist and >200-fold selective for ERβ.
TN2045	Pelargonidin-3-O-glucoside chloride	18466-51-8	98%
TN2045	Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflam...
T3645	Endoxifen E-isomer hydrochloride	1197194-61-8	98%
T3645	Endoxifen, a tamoxifen metabolite, is effective specific Estrogen Response Modifier (SERM).
T20720	Norethisterone enanthate	3836-23-5	98%
T20720	Norethindrone enanthate has antigonadotropic effects and can be used as a hormonal contraceptive. It is also a useful compound to study chem.-chem. interaction f...
T11230	ERRα antagonist-1	1072145-33-5	98%
T11230	ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferato...
T1579	Mestranol	72-33-3	98%
T1579	Mestranol, a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.