Glucocorticoid Receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response.

Cat. No.	Product name	CAS No.	Purity
T67742	EX-A5386	2452396-89-1	98%
T67742	EX-A5386 is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.
T32114	Hydrocortisone aceponate	74050-20-7	98%
T32114	Hydrocortisone aceponate is an effective topical glucocorticoid used in the form of a cream to treat various skin diseases.
T15000	Cort108297	1018679-79-2	98%
T15000	Cort108297 is a selective glucocorticoid receptor modulator and a selective GR antagonist with no affinity for other steroid receptors. Cort108297 showed a high ...
TN3910	Ecdysone	3604-87-3	98%
TN3910	Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
T14301	Apararenone	945966-46-1	98%
T14301	Apararenone is a novel antagonist of non-steroidal mineralocorticoid receptor, and for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis....
T15246	Esaxerenone	1632006-28-0	98%
T15246	Esaxerenone is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.
T1683	Actriol	547-81-9	95.35%
T1683	Actriol is always used as Glucocorticoid Receptor agonist.
T1666	Fludrocortisone acetate	514-36-3	97.6%
T1666	Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of ...
T0208	Prednisolone disodium phosphate	125-02-0	98%
T0208	Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
T15389L	Glucagon (1-29), bovine, human, porcine hydrochloride	28270-04-4	98%
T15389L	Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylatio...
T17217	Vamorolone	13209-41-1	98.04%
T17217	Vamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects...
T6580	Meprednisone	1247-42-3	98.07%
T6580	Betapar(Meprednisone) is a glucocorticoid and a methylated derivative of prednisone.
T15102	Dexamethasone palmitate	14899-36-6	98.08%
T15102	Dexamethasone palmitate is a prodrug of Dexamethasone and a glucocorticoid receptor agonist. It shows a 47-fold lower affinity for the glucocorticoid receptor th...
T0294	6α-Methylprednisolone 21-hemisuccinate sodium salt	2375-03-3	98.16%
T0294	METHYLPREDNISOLONE, a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
T3316	Fluorometholone	426-13-1	98.21%
T3316	Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon)...
T3096	Canrenoate potassium	2181-04-6	98.28%
T3096	Potassium canrenoate is a synthetic pregnadiene derivative with anti-aldosterone activity.
T1561	Clobetasol propionate	25122-46-7	98.44%
T1561	Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expre...
T4602	Hydrocortisone hemisuccinate	2203-97-6	98.7%
T4602	Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
T0337	Prednisolone acetate	52-21-1	98.85%
T0337	Prednisolone Acetate is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T14377	AZD5423	1034148-04-3	98.94%
T14377	AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in su...