s 7

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

(S)-7-O-Methylpeucedanol 3′-O-β-D-glucopyranoside is a coumarin glycoside [1].

Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to be determined. 1.Serhan, C.N., Gotlinger, K., Hong, S., et al.Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienesJ. Immunol.176(3)1848-1859(2006) 2.Ariel, A., and Serhan, C.N.Resolvins and protectins in the termination program of acute inflammationTRENDS in Immunology28(4)176-183(2007) 3.Schwab, J.M., Chiang, N., Arita, M., et al.Resolvin E1 and protectin D1 activate inflammation-resolution programmesNature447(7146)869-874(2007)

(11aR)-N,N-Bis((S)-1-phenylethyl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine is a useful organic compound for research related to life sciences and the catalog number is T64794.

(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T66550 and the CAS number is 314771-88-5.

(S)-N,N-Dimethyl-1,2,4,5,6,7-hexahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-12-amine is a useful organic compound for research related to life sciences. The catalog number is T67218 and the CAS number is 443965-10-4.

(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65672 and the CAS number is 106939-34-8.

(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine is a useful organic compound for research related to life sciences. The catalog number is T66391 and the CAS number is 314771-76-1.

(1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67324 and the CAS number is 900160-98-7.

(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65424 and the CAS number is 100986-89-8.

Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.

Zabicipril HCl（S 9650） is a potent angiotensin-converting enzyme inhibitor.

(S, R)-LSN 3318839 is an allosteric modulator of the glucagon-like peptide-3318839 receptor (GLP-1R) that has demonstrated powerful hypoglycemic effects in animal models alone or in combination with sitagliptin.

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.[3] RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice. [4][5][6] RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli. [6] Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.[7]

Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also

(2S)-4'-Hydroxy-7-methoxyflavan, a flavan, demonstrated significant cytotoxic effects on human leukemic Molt 4 cells [1].

The compound 6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy has been isolated from the stem of Angelica dahurica, marking its first discovery from a plant source [1].

(2S)-5-Methoxyflavan-7-ol (compound 2) is a natural product isolated from Dragon's blood resin [1].

Paeonilactone C significantly protects primary cultures of rat cortical cells against H2O2-induced neurotoxicity.

(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a palmitate derivative, is extracted from the root of Salvia miltiorrhiza. Compound 3 exhibits anti-cancer properties, demonstrating half-maximal cytotoxic concentrations (DC50s) of 25.5 μg/mL against HeLa, 37.5 μg/mL against HepG2, and 30.2 μg/mL against OVCAR-3 human cancer cell lines [1].

(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. Its metabolites participate in the synthesis of thymidine for incorporation into DNA or the synthesis of purines, as well as in the formation of methionine, which can be converted to the ubiquitous methyl donor, S-adenosylmethionine . THFA has also been used to study the activation of metabolite-binding riboswitches.

S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) is an enantiomer of dihydrodaidzein which is involved in equol biosynthesis in a lactic acid bacterium, Lactococcus sp. strain.

inhibits leukotriene B4 (LTB4)-induced polymorphonuclear neutrophils (PMN) chemotaxis

(S,R,S)-AHPC-C7-amine, also known as VH032-C7-amine, is a chemically synthesized conjugate that functions as an E3 ligase ligand-linker. This compound combines the VH032-based VHL ligand with a specific linker designed for the degradation of estrogen-related receptor α (ERRα) PROTAC.

(3β,24S)-3-Hydroxystigmast-5-en-7-one (Compound 31), isolated from Lindera akoensis, exhibits anti-inflammatory activity [1].

(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-7,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid is a useful organic compound for research related to life sciences and the catalog number is T64669.

(3aR,4S,7R,7aS)-Hexahydro-4,7-methanoisobenzofuran-1,3-dione is a useful organic compound for research related to life sciences. The catalog number is T65552 and the CAS number is 14166-28-0.

rel-(3aR,4S,7R,7aS)-3a,4,7,7a-Tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione is a useful organic compound for research related to life sciences. The catalog number is T64449 and the CAS number is 6265-30-1.

(S)-7,7'-Bis(bis(3,5-dimethylphenyl)phosphaneyl)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene] is a useful organic compound for research related to life sciences and the catalog number is T65595.

Biotin-PEG7-C2-S-Vidarabine is a polyethylene glycol (PEG)-based linker incorporating the adenosine analog, Vidarabine, an antiviral agent effective against herpes simplex and varicella zoster viruses [1].

7-Hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one hydrate(2:3) is a useful organic compound for research related to life sciences and the catalog number is T65146.

Estradiene dione-3-keta is a useful organic compound for research related to life sciences. The catalog number is T65148 and the CAS number is 5571-36-8.

[(2R,3S,4R,5R)-3,4-diacetyloxy-5-[2-amino-7-(cyclopropylmethyl)-8-oxopurin-9-yl]oxolan-2-yl]methyl acetate is a useful organic compound for research related to life sciences and the catalog number is TNU1306.

Paeonilactone A is a natural product of Paeonia, Paeoniaceae. The catalog number is TN2035 and the CAS number is 98751-79-2. Paeonilactone A can be used as a reference standard.

(S)-Metoprolol-d7 is a deuterated compound of (S)-Metoprolol. (S)-Metoprolol has a CAS number of 37350-58-6.

(R)-Methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate is a useful organic compound for research related to life sciences. The catalog number is T66656 and the CAS number is 10538-59-7.

(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid is a useful organic compound that has been used in life science related research.

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66996 and the CAS number is 104239-97-6.

(2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-Dihydroxy-4a,6a-dimethylhexadecahydro-1H-cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthren-7(7aH)-one is a useful organic compound for research related to life sciences. The catalog number is T67508 and the CAS number is 82543-16-6.

(8S,9S,10R,14S)-13-Ethyl-11-methylene-2,3,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(6H)-one is a useful organic compound for research related to life sciences. The catalog number is T66298 and the CAS number is 54024-21-4.

Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide is a useful organic compound for research related to life sciences and the catalog number is T67423.

(7R,8R,9S,13S,14S,17S)-7-(9-Bromononyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol is a useful organic compound for research related to life sciences. The catalog number is T66315 and the CAS number is 875573-67-4.

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67601 and the CAS number is 103335-55-3.

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate is a useful organic compound for research related to life sciences and the catalog number is T64681.

(2S)-5,7,3',4'-tetramethoxyflavanone is a useful organic compound for research related to life sciences and the catalog number is T124281.

S7, a peptide antagonist of the IL-6 receptor, concentration-dependently inhibits IL-6 binding to its receptor. At 50 µM, S7 suppresses IL-6-triggered elevations in VEGF levels within C-33 A cervical cancer cells and RPMI-8226 B cell lymphocytes. It significantly reduces tumor volume in a C-33 A cervical cancer mouse xenograft model with IL-6 overexpression, following a dosage regimen of 50 mg/kg bi-daily. Moreover, when linked to cysteine on lipid nanoparticles (LNPs) encapsulating doxorubicin, S7 enhances glioma targeting and improves survival rates in a U251 glioblastoma mouse xenograft model.

(2S)-5,7,3',5'-Tetrahydroxyflavanone is a compound isolated from Thymus quinquecostatus var. japonica [1].

t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is a useful organic compound for research related to life sciences. The catalog number is T66069 and the CAS number is 147489-06-3.

(S)-9-((tert-Butyldimethylsilyl)oxy)-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione is a useful organic compound for research related to life sciences and the catalog number is T64821.

(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate is a useful organic compound for research related to life sciences. The catalog number is T65075 and the CAS number is 17110-51-9.