N-Cbz-L-Leucine (N-[(Phenylmethoxy)carbonyl]-L-leucine) is a leucine derivative, a commonly used amino acid protecting group.

Tyrosylleucine is a dipeptide composed of tyrosine and leucine. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following

[D-Ala2]leucine-enkephalin acetate ([D-Ala2]leucine-enkephalin acetate (64963-01-5 free base)) is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.

[Leu5]-Enkephalin acetate(58822-25-6 free base) is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)

N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro. N-Oleoyl leucine (25 mg/kg, i.p.) decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model. It improves glucose homeostasis in a fasting glucose tolerance test and increases VO2 while slightly decreasing overall locomotor activity.

Dansylleucine is an agent of bioactive chemical.

[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.

Leucyl-leucyl-leucine is may be used for pH-dependent endosomal membrane disruption to release agents. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media.

Prolylleucine (((Benzyloxy)carbonyl)-L-prolyl-D-leucine) is a dipeptide containing branched-chain amino acids.

N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-leucine is a useful organic compound for research related to life sciences. The catalog number is T65042 and the CAS number is 73401-65-7.

Gamma-Methylleucine (2-Amino-3-tert-butylpropionic acid) is an auxiliary for copper-catalyzed asymmetric Michael reactions.

N-Acetyl-R-leucine is a useful organic compound for research related to life sciences. The catalog number is T66941 and the CAS number is 19764-30-8.

D-Leucine methyl ester hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66885 and the CAS number is 5845-53-4.

L-Leucine benzyl ester p-toluenesulfonate salt is a useful organic compound for research related to life sciences. The catalog number is T65805 and the CAS number is 1738-77-8.

Phenylalanylleucine is a bioactive chemical.

Lysyl-prolyl-isoleucyl-glutamyl-phenylalanyl-4-nitrophenylalanyl-arginyl-leucine is a bioactive chemical.

KSL-128114, a peptide inhibitor of the membrane regulator syntenin (Ki = 300 nM), notably diminishes the viability of A2058 melanoma and patient-derived glioblastoma multiforme (GBM) cells in a concentration-dependent manner. Furthermore, when administered at 50 µM, KSL-128114 elevates survival times in a patient-derived xenograft (PDX) mouse model of GBM, where mice were implanted intracranially with patient-derived GBM cells pre-cultured with KSL-128114.

Cyclo(Pro-Leu) (Cyclo-L-prolyl-L-leucine) is a marine-derived natural product with brine shrimp lethality.

[Leu5]-Enkephalin (Leu-enkephalin) is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)

Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.

H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eliminates lymphocytes with cytotoxic potential.

C-MYC PEPTIDE EPITOPE TFA, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope.

Lysyl aspartyl isoleucine (Tripeptide-10) is a bioactive peptide with anti-wrinkle effects and has been reported as a cosmetic ingredient.

Tyrosylleucine (Tyr-Leu, YL) TFA is a dipeptide compound with potent antidepressant-like activity. This orally active compound demonstrates effective modulation of depressive symptoms.

[Leu27]-Melan-A, MART-1 (26-35), is a biologically active peptide modified by substituting leucine for alanine at position 27, which enhances its HLA-A*0201 binding, immunogenicity, and antigenicity compared to the natural peptide. Pyroglutamyl (pGlu) peptides, arising from the spontaneous cyclization of glutamine (Q) or glutamic acid (E) at the N-terminus, are a recognized subset of peptides that may confer increased stability due to the hydrophobic γ-lactam ring of pGlu. These pGlu peptides are typically included during peptide purity assessments in HPLC analysis.

Tetrapeptide-11 is the reaction product of Acetic Acid and tetrapeptide-11, containing leucine, proline, and tyrosine residues. It boosts cell growth, Syndecan-1, and Collagen XVII synthesis. Tetrapeptide-11 has a face and body anti-wrinkle and anti-aging

H-Leu-Leu-Ala-OH, a tripeptide consisting of two L-leucine residues linked to L-alanine via peptide bonds, exhibits antioxidant activities [1].

[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing mice with this peptide (50 µg) mixed in complete Freund’s adjuvant (CFA) elevates IL-4 levels in the spleen. While it suppresses Th1 cell activation in vitro, it does not do so in vivo; instead, it promotes the development of regulatory T cells. Preimmunization with [Leu144, Arg147]-PLP (139-151) postpones the onset of experimental autoimmune encephalomyelitis (EAE) triggered by encephalitogenic peptides from PLP (178-191), myelin oligodendrocyte glycoprotein (MOG) (92-106), or myelin basic protein (MBP) in mice.

[Leu3]-Oxytocin, an oxytocin analogue, is a derivative of oxytocin wherein the leucine amino acid (Leu) has been substituted at the 3rd position in the sequence.

L-K6L9, a cytolytic peptide comprised of L-isomer leucine and lysine, demonstrates cytotoxicity against both androgen-independent (LNCaP-CL1) and androgen-dependent (22Rv1 and LNCaP) human prostate cancer cells, with LC50 values of 4, 4, and 6 µM, respectively. It also affects non-cancerous cells, including NIH3T3 mouse fibroblasts and OL human foreskin fibroblasts, with LC50s of 7 and 5 µM, respectively. Furthermore, at a concentration of 100 µM, L-K6L9 induces hemolysis in isolated human erythrocytes.

L-Leucyl-L-alanine is a simple dipeptide composed of L-leucine and L-alanine>[1].