progesterone

Progesterone (Pregn-4-ene-3,20-dione) is the major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production.

Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.

Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.

16a,17a-Epoxy-4-Pregnen-3,20-Dione is a synthetic progestin, a metabolite of the luteinizing hormone hormone, which acts by binding to the luteinizing hormone receptor. It has been used to study the effects of progesterone on reproductive organs, the effects of the hormone on cell growth and development, and the effects of the hormone on the immune system.

Levonorgestrel (D-Norgestrel) is a Progestin and Progestin-containing Intrauterine Device. The physiologic effect of levonorgestrel is by means of Inhibit Ovum Fertilization.

Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.

Ovalbumins is the main protein found in egg whites. Ovalbumins have various biological activities such as antibacterial, anticancer, antihypertensive, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in estrogen- or progesterone- treated fallopian tubes. Ovalbumins are commonly used as markers to study hormone control of gene expression in fallopian tubes.

Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.

16-Dehydroprogesterone is a endogenous Metabolite. 16-Dehydroprogesterone is a steroidal progestin.

17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression.

20α-Dihydroprogesterone, a metabolite of Progesterone, inhibits cell proliferation and migration in breast tissue. It also suppresses aromatase (aromatase) activity in MCF-7aro cells, with an IC50 value of approximately 5 μM.

11Beta-hydroxyprogesterone (11β-Hydroxyprogesterone) is an inhibitor of 11beta-hydroxysteroid dehydrogenase (11betaHSD) type 2, which activates the human hydrocorticosteroid receptor in COS-7 cells, and may be useful in the study of metabolism-related diseases.

5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, synthesized by androgen-responsive prostate cancer cells under starvation conditions.

Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist

5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone.

Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.

Isocupressic acid ((+)-Isocupressic acid) is an abortifacient isolated from pine needles and bark that blocks progesterone production in bovine corpus luteum cells.

Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 value of 10.46μM. Irilone potentiat