sterol

Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the inward-rectifier potassium ion channel.

Isomucronulatol 7-O-glucoside is a biologically active isoflavone isolated from Astragalus membranaceus.

Stigmasterol (Stigmasterin) is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.

5,6-Epoxyergosterol is derived from the endophytic fungus Phyllosticta capitalensis.

Ergosterol Acetate (Ergosta-5,7,22-trien-3-beta-yl acetate) is one of the acetate derivatives of Ergosterol from Monascus anka.

Beta-sitosterol is one of several plant-based substances known as phytosterols.

Lathosterol, a molecule akin to cholesterol, serves as a biomarker for the body's total cholesterol synthesis, as indicated by its serum concentration.

20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).

25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regulation of cholesterol biosynthesis

Campesterol ((24R)-5-Ergosten-3β-ol) is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory effect, it inhibits several pro-inflammatory and matrix degradation mediators typically involved in osteoarthritis- induced cartilage degradation, also sometimes used to treat some specific prostate conditions.

Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also used in the synthesis of several important hormones and bile acids.

Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.

'S-Campesterol (5-Ergosten-3β-ol) is a plant-derived sterol, commonly known as a phytosterol [1].'

Pseudotaraxasterol shows cytotoxic activity against MOLT-4 cells.

Ergosterol glucoside is a natural product from Rehmannia glutinosa.

Zymosterol, a metabolite in cholesterol biosynthesis and precursor to cholesterol, predominantly resides in the plasma membrane and circulates within the cell [1] [2].

7-Oxo-beta-sitosterol is a natural product of Knoxia, Rubiaceae. The catalog number is TN3248 and the CAS number is 2034-74-4. 7-Oxo-beta-sitosterol can be used as a reference standard.

Lumisterol (9β,10α-Ergosterol), a steroid compound and the (9β,10α)-stereoisomer of Ergosterol, serves as a photoprotective agent shielding against UVB-induced DNA damage and exhibits anti-proliferative activities[1].

Cholesterol glucuronide is an endogenous metabolite of lipid generated by UDP glucuonyltransferase in the liver.

Delta 7-avenasterol has antioxidant activity.

Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.

15-Deoxoeucosterol is a natural product of Scilla, Asparagaceae. The catalog number is TN2636 and the CAS number is 81241-53-4. 15-Deoxoeucosterol can be used as a reference standard.

Stellasterol is a nartural product from Ganoderma lucidum.

Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway.

22-Dehydroclerosterol, and cholesterol are sterol constituents.

24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.

Sycosterol A is an α-synuclein (α-syn) inhibitory sterol .

Ergosterol is the major sterol in fungi and has anti-inflammatory, antioxidant and antiproliferative properties.

22-Dihydrochondrillasterol, a natural product, is isolated from the root of Trichosanthes japonica [1].

Ikshusterol 3-O-glucoside has a potent snake-venom neutralizing capacity and it might be a potential molecule for the therapeutic treatment for snakebites.

Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits hACAT-1 and Lp-PLA2 inhibitory effec

Delta 5-avenasterol has antioxidant activity.

Conicasterol displays marked cytotoxic activity against human breast adenocarcinoma cell line (MCF-7) with the IC50 value of 6.23 ug/mL.

7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.

24-Methylcholesterol, a trans-ferulate ester extracted from rice bran, significantly inhibits TPA-induced inflammation [1].

3-Dehydro-15-deoxoeucosterol is a natural product from Scilla scilloides.

Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).

Ikshusterol is a natural product for research related to life sciences. The catalog number is TN4248 and the CAS number is 34427-61-7.

7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation.

24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an oxysterol compound that is an activator of the n-methyl-d-aspartate receptor (NMDA) and the transcription factor LXR, which has been used in the study of cardiogenesis and pancreatic cancer.

Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer. Although the exact mechanism of action of Beta-Sitosterol (SKF 14463) is unknown, it may be related to cholesterol metabolism or anti-inflammatory effects (via interference with prostaglandin metabolism). Beta-Sitosterol (SKF 14463) induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells.

7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][

24,25-Dihydrolanosterol (Lanostenol) is a chemical compound found in the seeds of the red pepper (Capsicum annuum).

6-O-Methylcerevisterol is a natural product for research related to life sciences. The catalog number is TN5292 and the CAS number is 126060-09-1.

7-Ketocholesterol is a metabolite of Cholesterol

8-Dehydrocholesterol is a compound whose elevated concentration is a diagnostic biochemical hallmark of classical Smith-Lemli-Opitz syndrome.

α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively.

Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C EBPα expression.

Cerevisterol is a cytotoxic steroid, can inhibit the activity of DNA polymerase alpha. It can stimulate NGF-mediated neurite outgrowth on PC12 cells.