T62238 |
AMPK activator 4
|
2493239-46-4
|
98%
|
|
AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. AMPK activator 4 selectively activates AMPK in muscle ti...
|
T15137 |
DK419
|
2102672-22-8
|
98%
|
|
DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM. DK419 decreases protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 an...
|
T20232 |
Kazinol B
|
99624-27-8
|
98%
|
|
Kazinol B is an inhibitor of nitric oxide (NO) production, an isopentenylated flavan with a dimethylpyran ring.Kazinol B improves insulin sensitivity by activati...
|
TN3042 |
4-Hydroxycinnamamide
|
194940-15-3
|
98%
|
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
|
TN5013 |
Shizukaol D
|
142279-42-3
|
98%
|
|
Shizukaol D exerts a growth inhibition effect on liver cancer cells in a dose- and time-dependent manner by modulating wnt signalling pathway. Shizukaol D may be...
|
T10105 |
3α-Hydroxymogrol
|
1343402-73-2
|
98%
|
|
3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle. It is a potent AMPK activator and enhances AMPK phosphorylation.
|
T11570 |
HL271
|
1422365-52-3
|
98%
|
|
HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.
|
T22460 |
XMD-17-51
|
1628614-50-5
|
98%
|
|
XMD-17-51 is a potent and highly selective NUAK1 inhibitor.
|
TN4382 |
Kazinol A
|
99624-28-9
|
98%
|
|
Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M ag...
|
T10312 |
Ampkinone
|
1233082-79-5
|
98%
|
|
Ampkinone is an indirect AMPK activator.
|
TL0014 |
Pinusolide
|
31685-80-0
|
98%
|
|
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a...
|
T14149 |
AICAR phosphate
|
681006-28-0
|
98%
|
|
AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism. It inhibits proinf...
|
TN1868 |
Ligupurpuroside A
|
147396-01-8
|
98%
|
|
Ligupurpuroside A has antioxidant,and hypolipidemic effects, it can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol/L.
|
T1456 |
Doxorubicin
|
23214-92-8
|
98%
|
|
Doxorubicin is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.
|
T16113 |
ML753286
|
1699720-89-2
|
98%
|
|
ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (...
|
TN1870 |
Ligupurpuroside C
|
1194056-33-1
|
98%
|
|
Ligupurpuroside C can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol/L.
|
T16166 |
N-[(4-Aminophenyl)methyl]adenosine
|
95523-13-0
|
98%
|
|
N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase).
|
TN1670 |
Ganodermanondiol
|
107900-76-5
|
98%
|
|
Ganodermanondiol exhibits potent cytoprotective effects on t-BHP-induced hepatotoxicity in human liver-derived HepG2 cells, presumably through Nrf2-mediated anti...
|
TN5431 |
Icariside E4
|
126253-42-7
|
98%
|
|
Icariside E4 is a natural compound derived from Ulmus minor that acts via AMPK phosphorylation and inhibition of MID1IP2 hypolipidation in HepG1 cells.Icariside ...
|
T13371 |
YM-53601 free base
|
182959-28-0
|
98%
|
|
YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.
|