T11518 |
GW274150 phosphate
|
438542-15-5
|
98%
|
|
GW274150 phosphate is a selective, orally active, and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50: 2.19 μM; Kd: 40 nM) and ra...
|
TN4602 |
Myricananin A
|
1079941-35-7
|
98%
|
|
Myricadenin A exhibits anti-inflammatory activities in the iNOS assay with EC50 values of 18.1 uM.
|
TN4286 |
Isodunnianol
|
139726-30-0
|
98%
|
|
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0...
|
TN4683 |
Nyasol
|
96895-25-9
|
98%
|
|
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory ...
|
TN2327 |
Zedoarondiol
|
98644-24-7
|
98%
|
|
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs...
|
TN5192 |
Tuberosin
|
41347-45-9
|
98%
|
|
Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in a dose dependent manner....
|
T3426 |
Bacoside A
|
11028-00-5
|
98%
|
|
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
|
T7206 |
2-Iminobiotin
|
13395-35-2
|
98%
|
|
2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of ...
|
T4S1616 |
Sanggenon D
|
81422-93-7
|
98%
|
|
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamma...
|
TN5186 |
Triptoquinone A
|
142950-86-5
|
98%
|
|
Triptoquinone A may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. Triptoquinone A has anti-inflammatory...
|
TN4635 |
Neoechinulin A
|
51551-29-2
|
98%
|
|
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
|
TN5019 |
Siegeskaurolic acid
|
52645-97-3
|
98%
|
|
Siegeskaurolic acid exhibits anti-inflammatory and antinociceptive effects, which due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via...
|
TN1890 |
Lupeol acetate
|
1617-68-1
|
98%
|
|
Lupeol acetate possesses antinociceptive, antifertility, and anti-inflammatory properties, the effect probably involves the opioid system, as indicated by the co...
|
TN2641 |
15-Methoxypinusolidic acid
|
769928-72-5
|
98%
|
|
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methox...
|
T13628 |
Curvularin
|
10140-70-2
|
98%
|
|
Curvulin, naturally isolated from Campylobacter curvulans, is a fungal metabolite and a potent mycotoxin that inhibits cytokine-induced nitric oxide synthase (iN...
|
T11518L |
GW274150
|
210354-22-6
|
98%
|
|
GW274150 shows less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 is a selective and NADPH-dependent inhibitor of huma...
|
TN3635 |
Chlojaponilactone B
|
1449382-91-5
|
98%
|
|
Chlojaponilactone B has anti-inflammatory activity, it exhibits pronounced inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264...
|
TN5164 |
Trans-Hinokiresinol
|
17676-24-3
|
98%
|
|
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
|
TN4050 |
Fargesone A
|
116424-69-2
|
98%
|
|
Fargesone A shows inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774....
|
TN1949 |
Moracin C
|
69120-06-5
|
98%
|
|
Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds.
|