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Microbiology&virology HBV

HBV

Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver. It can cause both acute and chronic infection. Many people have no symptoms during the initial infection.Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver. It can cause both acute and chronic infection. Many people have no symptoms during the initial infection.
Cat No. product name
T0085 Entecavir hydrate Entecavir is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog.
T0085L Entecavir Entecavir is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares...
T0308 Etidronate Etidronic is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
T1041 Risedronate Sodium Risedronate sodium is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatmen...
T1337 Pamidronate disodium salt Pamidronate disodium, a nitrogen-containing bisphosphonate, can help to strengthen bones.
T1599L Ibandronate sodium Ibandronate Sodium is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
T3449 Bay 41-4109 racemate BAY 41-4109 racemate is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
T3978 GSK2330672 GSK2330672 is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellen...
T4121 Bicyclol Bicyclol(SY 801) is an anti-hepatitis drug. Oral administration of bicyclol normalizes the elevated serum transaminases (ALT, AST) by 50% in chronic viral hepat...
T5832 Besifovir Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV...
TQ0017 AB-423 AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).
T7365 Inarigivir Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA.
T4475 JNJ-632 JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
TN1482 Chamaechromone Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α±-naphthoflavone, and predominantly catalyzed by r...
TN1732 Herpetone Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity.
TN1956 Mulberrofuran G Mulberrofuran G shows moderate activity, inhibits hepatitis B virus (HBV) DNA replication with the IC(50) value of 3.99 μM.
TN2220 (+)-Sophoranol (+)-Sophoranol exhibits antiviral activity against the Coxsackie virus B3. It also shows potent anti-HBV activity with an inhibitory potency against HBsAg secre...
TN1815 Kadsulignan L Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC...
TN1840 Kurarinol Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts vary...
TN2088 Platycodin D2 Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as...
T12097 Morphothiadin Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV (IC50 of 12 nM).
T10480L Bay 41-4109 BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).
T12724 RIG-1 modulator 1 RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.
T10480 Bay 41-4109 (less active enantiomer) Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).
T16870 Selgantolimod Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
TN3012 4,5-Dihydroblumenol A 4, 5-Dihydroblumenol shows significant inhibition against HepG2 cells transected with cloned hepatitis B virus DNA.
TN3687 Coclauril Coclauril shows anti-Hepatitis B virus (HBV) activities, with EC50 values of 7.6 ± 0.5 ug/mL.
TN4660 Niranthin Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competiti...
TN4750 Periglaucine A Periglaucine A inhibits hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.
TN4751 Periglaucine B Periglaucine B can inhibit hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.
Entecavir hydrate
T0085CAS 209216-23-9
Entecavir is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog.
Entecavir
T0085LCAS 142217-69-4
Entecavir is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares...
Etidronate
T0308CAS 2809-21-4
Etidronic is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
Risedronate Sodium
T1041CAS 115436-72-1
Risedronate sodium is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatmen...
Pamidronate disodium salt
T1337CAS 57248-88-1
Pamidronate disodium, a nitrogen-containing bisphosphonate, can help to strengthen bones.
Ibandronate sodium
T1599LCAS 138844-81-2
Ibandronate Sodium is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
Bay 41-4109 racemate
T3449CAS 298708-79-9
BAY 41-4109 racemate is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
GSK2330672
T3978CAS 1345982-69-5
GSK2330672 is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellen...
Bicyclol
T4121CAS 118159-48-1
Bicyclol(SY 801) is an anti-hepatitis drug. Oral administration of bicyclol normalizes the elevated serum transaminases (ALT, AST) by 50% in chronic viral hepat...
Besifovir
T5832CAS 441785-25-7
Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV...
AB-423
TQ0017CAS 1572510-80-5
AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).
Inarigivir
T7365CAS 475650-36-3
Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA.
JNJ-632
T4475CAS 1572510-42-9
JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
Chamaechromone
TN1482CAS 93413-00-4
Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α±-naphthoflavone, and predominantly catalyzed by r...
Herpetone
TN1732CAS 951677-22-8
Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity.
Mulberrofuran G
TN1956CAS 87085-00-5
Mulberrofuran G shows moderate activity, inhibits hepatitis B virus (HBV) DNA replication with the IC(50) value of 3.99 μM.
(+)-Sophoranol
TN2220CAS 3411-37-8
(+)-Sophoranol exhibits antiviral activity against the Coxsackie virus B3. It also shows potent anti-HBV activity with an inhibitory potency against HBsAg secre...
Kadsulignan L
TN1815CAS 163660-06-8
Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC...
Kurarinol
TN1840CAS 855746-98-4
Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts vary...
Platycodin D2
TN2088CAS 66663-90-9
Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as...
Morphothiadin
T12097CAS 1092970-12-1
Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV (IC50 of 12 nM).
Bay 41-4109
T10480LCAS 298708-81-3
BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).
RIG-1 modulator 1
T12724CAS 1428729-63-8
RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.
Bay 41-4109 (less active enantiomer)
T10480CAS 476617-51-3
Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).
Selgantolimod
T16870CAS 2004677-13-6
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
4,5-Dihydroblumenol A
TN3012CAS 155418-97-6
4, 5-Dihydroblumenol shows significant inhibition against HepG2 cells transected with cloned hepatitis B virus DNA.
Coclauril
TN3687CAS 127350-68-9
Coclauril shows anti-Hepatitis B virus (HBV) activities, with EC50 values of 7.6 ± 0.5 ug/mL.
Niranthin
TN4660CAS 50656-77-4
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competiti...
Periglaucine A
TN4750CAS 1025023-04-4
Periglaucine A inhibits hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.
Periglaucine B
TN4751CAS 1025023-05-5
Periglaucine B can inhibit hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.