HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.

Cat. No.	Product name	CAS No.	Purity
TQ0090	Nesbuvir	691852-58-1	98%
TQ0090	Nesbuvir (HCV-796) is a nonnucleoside inhibitor of the HCV nonstructural protein 5B (NS5B) polymerase.
T12956	Sofosbuvir impurity A	1496552-16-9	98%
T12956	Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
T9567	Samatasvir	1312547-19-5	98%
T9567	Samatasvir is a pan-genotypic inhibitor of the HCV non-structural protein 5A.
T5539	GS-443902	1355149-45-9	98%
T5539	GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
T12969	Sofosbuvir impurity N	1394157-34-6	98%
T12969	Sofosbuvir impurity N is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T14555	BI-1230	849022-32-8	98%
T14555	BI-1230 is potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication and it is also highly selective against other serine/cysteine protea...
TQ0122	VCH-916	1200133-34-1	98%
TQ0122	VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.
T26815	BILB-1941	494856-61-0	98%
T26815	BILB-1941 is an inhibitor of HCV NS5B polymerase and can be used in studies about HCV infection.
TQ0162	R-1479	478182-28-4	98%
TQ0162	R-1479 is an HCV replication inhibitor in the HCV subgenomic replicon system (IC50: 1.28 μM).
T12033	Micrococcin P1	67401-56-3	98%
T12033	Micrococcin P1 is a macrocyclic peptide antibiotic and is a potent hepatitis C virus (HCV) inhibitor(EC50 range of 0.1-0.5 μM)
TN5079	Sulochrin	519-57-3	98%
TN5079	Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotox...
T10067	2',5-Difluoro-2'-deoxycytidine	581772-30-7	98%
T10067	2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.
TN5263	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one	569-83-5	98%
TN5263	Xanthohumol, prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus. Xanthohumol is effective against HIV-1 and...
T12966	Sofosbuvir impurity K	1496552-51-2	98%
T12966	Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T14095	ACH-806	870142-71-5	98%
T14095	ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
TQ0030	Tomeglovir	233254-24-5	98%
TQ0030	Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).
T6200	Ledipasvir	1256388-51-8	98%
T6200	Ledipasvir is a Hepatitis C Virus NS5A Inhibitor. The mechanism of action of ledipasvir is as a P-Glycoprotein Inhibitor, and Breast Cancer Resistance Protein In...
T16774	RO-9187	876708-03-1	98%
T16774	RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).
T12963	Sofosbuvir impurity H	T12963	98%
T12963	Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is a diastereoisomer of Sofosbuvir.Sofosbuvir is an...
TN1703	Glycyrin	66056-18-6	98%
TN1703	Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.