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HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.
Cat. No. Product name CAS No. Purity Chemical Structure
T16774 RO-9187 876708-03-1 98%
RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).
T14555 BI-1230 849022-32-8 98%
BI-1230 is potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication and it is also highly selective against other serine/cysteine protea...
TN1033 Sennidin A 641-12-3 98%
Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.
TN4404 Ladanein 10176-71-3 98%
Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radic...
T12956 Sofosbuvir impurity A 1496552-16-9 98%
Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
T12964 Sofosbuvir impurity I T12964 98%
Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T5539 GS-443902 1355149-45-9 98%
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
TN1703 Glycyrin 66056-18-6 98%
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
T14095 ACH-806 870142-71-5 98%
ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
TQ0030 Tomeglovir 233254-24-5 98%
Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).
TQ0122 VCH-916 1200133-34-1 98%
VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.
T13281 Valopicitabine 640281-90-9 98%
Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic ...
TN5079 Sulochrin 519-57-3 98%
Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotox...
TN3438 Arborinine 5489-57-6 98%
Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0....
TN1034 Sennidin B 517-44-2 98%
Sennidin B stimulates glucose incorporation in rat adipocytes.
T16675 PSI-352938 1231747-17-3 98%
PSI-352938 is an inhibitor of hepatitis C virus nucleotide.
T12968 Sofosbuvir impurity M 2095551-10-1 98%
Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12967 Sofosbuvir impurity L T12967 98%
Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T10067 2',5-Difluoro-2'-deoxycytidine 581772-30-7 98%
2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.
TN1138 γ-Fagarine 524-15-2 98%
gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)-i...
RO-9187
T16774
RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).
BI-1230
T14555
BI-1230 is potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication and it is also highly selective against other serine/cysteine protea...
Sennidin A
TN1033
Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.
Ladanein
TN4404
Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radic...
Sofosbuvir impurity A
T12956
Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
Sofosbuvir impurity I
T12964
Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
GS-443902
T5539
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
Glycyrin
TN1703
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
ACH-806
T14095
ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
Tomeglovir
TQ0030
Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).
VCH-916
TQ0122
VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.
Valopicitabine
T13281
Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic ...
Sulochrin
TN5079
Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotox...
Arborinine
TN3438
Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0....
Sennidin B
TN1034
Sennidin B stimulates glucose incorporation in rat adipocytes.
PSI-352938
T16675
PSI-352938 is an inhibitor of hepatitis C virus nucleotide.
Sofosbuvir impurity M
T12968
Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
Sofosbuvir impurity L
T12967
Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
2',5-Difluoro-2'-deoxycytidine
T10067
2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.
γ-Fagarine
TN1138
gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)-i...
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