HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.

Cat. No.	Product name	CAS No.	Purity
T16774	RO-9187	876708-03-1	98%
T16774	RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).
T14555	BI-1230	849022-32-8	98%
T14555	BI-1230 is potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication and it is also highly selective against other serine/cysteine protea...
TN1033	Sennidin A	641-12-3	98%
TN1033	Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.
TN4404	Ladanein	10176-71-3	98%
TN4404	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radic...
T12956	Sofosbuvir impurity A	1496552-16-9	98%
T12956	Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
T12964	Sofosbuvir impurity I	T12964	98%
T12964	Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T5539	GS-443902	1355149-45-9	98%
T5539	GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
TN1703	Glycyrin	66056-18-6	98%
TN1703	Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
T14095	ACH-806	870142-71-5	98%
T14095	ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
TQ0030	Tomeglovir	233254-24-5	98%
TQ0030	Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).
TQ0122	VCH-916	1200133-34-1	98%
TQ0122	VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.
T13281	Valopicitabine	640281-90-9	98%
T13281	Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic ...
TN5079	Sulochrin	519-57-3	98%
TN5079	Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotox...
TN3438	Arborinine	5489-57-6	98%
TN3438	Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0....
TN1034	Sennidin B	517-44-2	98%
TN1034	Sennidin B stimulates glucose incorporation in rat adipocytes.
T16675	PSI-352938	1231747-17-3	98%
T16675	PSI-352938 is an inhibitor of hepatitis C virus nucleotide.
T12968	Sofosbuvir impurity M	2095551-10-1	98%
T12968	Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12967	Sofosbuvir impurity L	T12967	98%
T12967	Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T10067	2',5-Difluoro-2'-deoxycytidine	581772-30-7	98%
T10067	2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.
TN1138	γ-Fagarine	524-15-2	98%
TN1138	gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)-i...