amino peg3 c2 amine

Amino-PEG3-C2-Amine, a PEG-based linker with three units, is utilized in PROTAC synthesis.

Propargyl-PEG3-amine (Propargyl-PEG3-NH2) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

Amino-PEG13-amine (H2N-PEG13-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Bromo-PEG3-C2-acid, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis[1].

Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a 3-unit PEG linker, used in PROTAC technology.

Amino-PEG11-amine, a polyethylene glycol (PEG)-based linker with 12 units, facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands. This strategy enhances the preparation of selective and potent estrogen receptor (ER) antagonists, offering an innovative approach for endocrine therapy in breast cancer treatment.

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a polyethylene glycol (PEG)-based linker designed for constructing PROTACs.

Chloroacetamido-C-PEG3-C3-NHBoc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Amine-PEG-amine (MW 35000), a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].

Fluorescein-PEG3-amine is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bromo-PEG3-C2-phosphonic acid, a polyethylene glycol (PEG) derivative, serves as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Amino-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Aminooxy-PEG3-C2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable triethylene glycol linker featuring propargyl and N-hydroxysuccinimide (NHS) functional groups, used in the synthesis of antibody-drug conjugates (ADCs)[1].

Amino-PEG27-amine, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Amino-PEG23-amine is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands, which is crucial for creating PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized E3 ligase ligand-linker conjugate, incorporating the cereblon ligand from Pomalidomide and a linker used in PROTAC technology. It facilitates targeted protein degradation by modulating E3 ligase activity, thereby enabling the selective elimination of specific proteins of interest.

Azide-PEG-amine (MW 3500) is a polyethylene glycol (PEG) linker compound, designed for the synthesis of proteolysis targeting chimeric molecules (PROTACs)[1].

Biotin-C1-PEG3-C3-amine (TFA) is a polyethylene glycol (PEG) linker essential for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Boc-Gly-amido-C-PEG3-C3-amine is a polyethylene glycol (PEG)-based PROTAC linker used in PROTAC synthesis [1].

NHPI-PEG3-C2-Pfp ester is a trifunctional polyethylene glycol (PEG) linker molecule used specifically in the fabrication of antibody-drug conjugates (ADCs).

Azido-PEG3-C-Boc is a PEG-based linker for PROTACs that connects two essential ligands, crucial for the formation of PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Acid-C2-PEG3-NHS ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

NHPI-PEG3-C2-NHS ester is a noncleavable, three-unit PEG linker used specifically for the synthesis of antibody-drug conjugates (ADCs).

Tos-PEG3-C2-methyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Tri(Amino-PEG4-amide)-amine is a polyethylene glycol (PEG)-based linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

Amino-PEG4-C2-amine, a PEG-based linker (4 units) for PROTAC development, facilitates the synthesis of PROTACs.

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used in the development of antibody-drug conjugates (ADCs).

Hydroxy-Amino-bis(PEG1-C2-Boc) is an alkyl ether-based linker utilized in the synthesis of PROTACs [1].

Amino-PEG2-C2-hydrazide-Boc is a polyethylene glycol (PEG)-based linker used for synthesizing proteolysis targeting chimeras (PROTACs)[1].

m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Amino-PEG6-amine, a polyethylene glycol-based (PEG-based) linker with six units, is utilized for the synthesis of PROTACs.

NH-bis(PEG3-C2-NH-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Amino-PEG3-C2-acid, a cleavable PEG ADC linker, is used in the synthesis of antibody-drug conjugates (ADCs) [1].

Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC1-PEG3-alkylC3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

A 410099.1 amide-PEG3-amine-Boc is an IAP ligand-based functionalized molecule commonly used in PROTACs, consisting of an IAP ligand and an amide-PEG3 linker with a terminal amine. The compound effectively conjugates with target protein ligands.

DBCO-PEG3-amine, a PEG-based linker for PROTACs, joins two essential ligands and facilitates the formation of PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Amine-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].