T0180 |
Benazepril hydrochloride |
Benazepril is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril is associated with a low rate of transient...
|
T0215 |
Losartan potassium |
Losartan, an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor. |
T0215L |
Losartan |
Losartan is an angiotensin II receptor antagonist. |
T0706 |
Lisinopril dihydrate |
Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
T0805 |
Quinapril hydrochloride |
Quinapril is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril is associated with a l...
|
T10323 |
Angiotensin II (3-8), human TFA |
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity. |
T1057 |
Azilsartan |
Azilsartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect...
|
T11642 |
Imidaprilate |
Imidaprilate is used in the research of hypertensive disease. Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme...
|
T11808 |
L162389 |
L162389 is a potent angiotensin AT1 receptor antagonist with Ki of 28 nM. |
T11809 |
L162441 |
L162441 is an antagonist of Angiotensin type 1 receptor. |
T12704 |
Rentiapril |
Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity. |
T13865 |
Resorcinolnaphthalein |
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM). |
T14123 |
ACT 178882 |
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM). |
T1461 |
Candesartan |
Candesartan is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure. |
T1462 |
Captopril |
Captopril is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and impor...
|
T1484L |
Perindopril erbumine |
Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihype...
|
T1489 |
Fosinopril sodium |
Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug th...
|
T1518 |
Benicar |
Olmesartan medoxomil is an angiotensin II type 1 receptor blocker that is used to manage hypertension. |
T1520 |
Aliskiren hemifumarate |
Aliskiren Hemifumarate is an orally active nonpeptide renin inhibitor with antihypertensive activity. |
T1570 |
Telmisartan |
Telmisartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist. |
T1605 |
Enalapril |
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
T1615 |
Irbesartan |
Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist. |
T16385 |
Omapatrilat |
Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively). |
T1645 |
Ramipril |
Ramipril is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat. |
T16544 |
Pivalopril |
Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme. |
T16573 |
Pratosartan |
Pratosartan is a selective antagonist of angiotensin II receptor. |
T19187 |
Aliskiren D6 hemifumarate |
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50:...
|
T1940 |
BTB06584 |
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising ...
|
T2270 |
Trans-Tranilast |
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indication...
|
T2318 |
LCZ696 |
LCZ696 is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure. |
T2322 |
Fimasartan |
Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fima...
|
T2400 |
Candesartan Cilexetil |
Candesartan Cilexetil is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal...
|
T2531 |
Eprosartan Mesylate |
Eprosartan is a competitive and reversible Angiotensin II Receptor Blocker. |
T3064 |
VTP-27999 |
VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function. |
T3178 |
BIBS 39 |
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. |
T3281 |
Delapril Hydrochloride |
Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhi...
|
T3461 |
Losartan Carboxylic Acid |
EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, ...
|
T4431 |
EMA401 |
EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyper...
|
T5030 |
Zofenopril (calcium) |
Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metaboli...
|
T5355 |
Sparsentan |
Sparsentan is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respectively) |
T5701 |
OPHIOPOGONIN D |
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation. |
T5796 |
Plantainoside D |
Plantainoside D shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vit...
|
T5824 |
Angiotensin IV |
Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor. |
T5964 |
Olmesartan |
Olmesartan is an Angiotensin II Type I receptor antagonist. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil,and has antihyperte...
|
T6067 |
PD123319 |
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist. |
T6133 |
Remodelin hydrobromide |
Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. |
T6219 |
Azilsartan Medoxomil |
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults w...
|
T6340 |
Enalaprilat Dihydrate |
Enalaprilat(IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor. |
T6444 |
Cilazapril Monohydrate |
Cilazapril Monohydrate is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. |
T6486 |
Enalapril Maleate |
Enalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension,chronic heart failure , and diabetic nephro...
|
T6542 |
Imidapril HCl |
Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. |
T6595 |
Moexipril HCl |
Moexipril HCl is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart f...
|
T6698 |
Temocapril HCl |
Temocapril HCl, the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension. |
T6716 |
Valsartan |
Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension. |
T7040 |
Angiotensin II human |
Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I con...
|
T7339 |
Angiotensin 1-7 |
Angiotensin 1-7, also known as Ang-(1-7), is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0....
|
T7354 |
H-Val-Pro-Pro-OH |
H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM). |
T7510 |
Leucylarginylproline |
Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM). |
T7577 |
Angiotensin III, human, mouse(3TFA) |
Angiotensin III, human, mouse(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM). |
T7616 |
A 779(3TFA) |
A 779(3TFA) is a potent antagonist of angiotensin-(1-7) receptor |
T7668 |
VTP-27999 TFA |
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM). |
T7686 |
Ramiprilat |
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
T7743 |
ANGIOTENSIN IV TFA(12676-15-2(free base)) |
ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor. |
T7797 |
Tasosartan |
Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM). |
T7808 |
Alacepril |
Alacepril is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive |
T8270 |
Deserpidine |
Deserpidine is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) ...
|
T8560 |
Angiotensin II acetate |
Angiotensin II acetate is a vasoconstrictor that mainly acts on the AT1 receptor. |
TN1464 |
Camellianin A |
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7...
|
TN4431 |
Leucosceptoside A |
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosid...
|
TP1187 |
CNP (1-22), human |
C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. |
TP2158 |
TRV-120027 TFA |
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling. |
TQ0057 |
AVE 0991 |
AVE 0991 is a small molecular and orally active agonist of angiotensin-(1-7) receptor (IC50: 21 nM). |