Cart
Endocrinology/Hormones RAAS

RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
Cat No. product name
T0180 Benazepril hydrochloride Benazepril is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril is associated with a low rate of transient...
T0215 Losartan potassium Losartan, an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
T0215L Losartan Losartan is an angiotensin II receptor antagonist.
T0706 Lisinopril dihydrate Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T0805 Quinapril hydrochloride Quinapril is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril is associated with a l...
T1057 Azilsartan Azilsartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect...
T1461 Candesartan Candesartan is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T1462 Captopril Captopril is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and impor...
T1484L Perindopril erbumine Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihype...
T1489 Fosinopril sodium Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug th...
T1518 Benicar Olmesartan medoxomil is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
T1520 Aliskiren hemifumarate Aliskiren Hemifumarate is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T1570 Telmisartan Telmisartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
T1605 Enalapril Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1615 Irbesartan Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T1645 Ramipril Ramipril is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.
T1940 BTB06584 BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising ...
T2270 Trans-Tranilast Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indication...
T2318 LCZ696 LCZ696 is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.
T2322 Fimasartan Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fima...
T2400 Candesartan Cilexetil Candesartan Cilexetil is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal...
T2531 Eprosartan Mesylate Eprosartan is a competitive and reversible Angiotensin II Receptor Blocker.
T3064 VTP-27999 VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
T3178 BIBS 39 BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
T3281 Delapril Hydrochloride Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhi...
T3461 Losartan Carboxylic Acid EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, ...
T6067 PD123319 PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist.
T6133 Remodelin hydrobromide Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
T6219 Azilsartan Medoxomil Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults w...
T6340 Enalaprilat Dihydrate Enalaprilat(IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.
T6444 Cilazapril Monohydrate Cilazapril Monohydrate is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
T6486 Enalapril Maleate Enalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension,chronic heart failure , and diabetic nephro...
T6542 Imidapril HCl Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
T6595 Moexipril HCl Moexipril HCl is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart f...
T6698 Temocapril HCl Temocapril HCl, the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
T6716 Valsartan Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
T7040 Angiotensin II human Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I con...
T4431 EMA401 EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyper...
T5030 Zofenopril (calcium) Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metaboli...
T5701 OPHIOPOGONIN D Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
T5964 Olmesartan Olmesartan is an Angiotensin II Type I receptor antagonist. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil,and has antihyperte...
T5796 Plantainoside D Plantainoside D shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vit...
T5824 Angiotensin IV Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.
T7339 Angiotensin 1-7 Angiotensin 1-7, also known as Ang-(1-7), is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0....
T7354 H-Val-Pro-Pro-OH H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).
T7668 VTP-27999 TFA VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
T7686 Ramiprilat Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T7743 ANGIOTENSIN IV TFA(12676-15-2(free base)) ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.
TQ0057 AVE 0991 AVE 0991 is a small molecular and orally active agonist of angiotensin-(1-7) receptor (IC50: 21 nM).
T7797 Tasosartan Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
Benazepril hydrochloride
T0180CAS 86541-74-4
Benazepril is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril is associated with a low rate of transient...
Losartan potassium
T0215CAS 124750-99-8
Losartan, an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
Losartan
T0215LCAS 114798-26-4
Losartan is an angiotensin II receptor antagonist.
Lisinopril dihydrate
T0706CAS 83915-83-7
Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Quinapril hydrochloride
T0805CAS 82586-55-8
Quinapril is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril is associated with a l...
Azilsartan
T1057CAS 147403-03-0
Azilsartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect...
Candesartan
T1461CAS 139481-59-7
Candesartan is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
Captopril
T1462CAS 62571-86-2
Captopril is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and impor...
Perindopril erbumine
T1484LCAS 107133-36-8
Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihype...
Fosinopril sodium
T1489CAS 88889-14-9
Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug th...
Benicar
T1518CAS 144689-63-4
Olmesartan medoxomil is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
Aliskiren hemifumarate
T1520CAS 173334-58-2
Aliskiren Hemifumarate is an orally active nonpeptide renin inhibitor with antihypertensive activity.
Telmisartan
T1570CAS 144701-48-4
Telmisartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
Enalapril
T1605CAS 75847-73-3
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Irbesartan
T1615CAS 138402-11-6
Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
Ramipril
T1645CAS 87333-19-5
Ramipril is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.
BTB06584
T1940CAS 219793-45-0
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising ...
Trans-Tranilast
T2270CAS 70806-55-2
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indication...
LCZ696
T2318CAS 936623-90-4
LCZ696 is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.
Fimasartan
T2322CAS 247257-48-3
Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fima...
Candesartan Cilexetil
T2400CAS 145040-37-5
Candesartan Cilexetil is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal...
Eprosartan Mesylate
T2531CAS 144143-96-4
Eprosartan is a competitive and reversible Angiotensin II Receptor Blocker.
VTP-27999
T3064CAS 942142-51-0
VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
BIBS 39
T3178CAS 133085-33-3
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
Delapril Hydrochloride
T3281CAS 83435-67-0
Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhi...
Losartan Carboxylic Acid
T3461CAS 124750-92-1
EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, ...
PD123319
T6067CAS 130663-39-7
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist.
Remodelin hydrobromide
T6133CAS 1622921-15-6
Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
Azilsartan Medoxomil
T6219CAS 863031-21-4
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults w...
Enalaprilat Dihydrate
T6340CAS 84680-54-6
Enalaprilat(IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.
Cilazapril Monohydrate
T6444CAS 92077-78-6
Cilazapril Monohydrate is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
Enalapril Maleate
T6486CAS 76095-16-4
Enalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension,chronic heart failure , and diabetic nephro...
Imidapril HCl
T6542CAS 89396-94-1
Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
Moexipril HCl
T6595CAS 82586-52-5
Moexipril HCl is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart f...
Temocapril HCl
T6698CAS 110221-44-8
Temocapril HCl, the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
Valsartan
T6716CAS 137862-53-4
Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
Angiotensin II human
T7040CAS 4474-91-3
Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I con...
EMA401
T4431CAS 1316755-16-4
EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyper...
Zofenopril (calcium)
T5030CAS 81938-43-4
Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metaboli...
OPHIOPOGONIN D
T5701CAS 945619-74-9
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
Olmesartan
T5964CAS 144689-24-7
Olmesartan is an Angiotensin II Type I receptor antagonist. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil,and has antihyperte...
Plantainoside D
T5796CAS 147331-98-4
Plantainoside D shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vit...
Angiotensin IV
T5824CAS 12676-15-2
Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.
Angiotensin 1-7
T7339CAS 51833-78-4
Angiotensin 1-7, also known as Ang-(1-7), is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0....
H-Val-Pro-Pro-OH
T7354CAS 58872-39-2
H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).
VTP-27999 TFA
T7668CAS 1013937-63-7
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
Ramiprilat
T7686CAS 87269-97-4
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
ANGIOTENSIN IV TFA(12676-15-2(free base))
T7743CAS T7743
ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.
AVE 0991
TQ0057CAS 304462-19-9
AVE 0991 is a small molecular and orally active agonist of angiotensin-(1-7) receptor (IC50: 21 nM).
Tasosartan
T7797CAS 145733-36-4
Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).