RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.

Cat No.	product name
T0180	Benazepril hydrochloride	Benazepril is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril is associated with a low rate of transient...
T0215	Losartan potassium	Losartan, an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
T0215L	Losartan	Losartan is an angiotensin II receptor antagonist.
T0706	Lisinopril dihydrate	Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T0805	Quinapril hydrochloride	Quinapril is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril is associated with a l...
T1057	Azilsartan	Azilsartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect...
T1461	Candesartan	Candesartan is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T1462	Captopril	Captopril is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and impor...
T1484L	Perindopril erbumine	Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihype...
T1489	Fosinopril sodium	Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug th...
T1518	Benicar	Olmesartan medoxomil is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
T1520	Aliskiren hemifumarate	Aliskiren Hemifumarate is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T1570	Telmisartan	Telmisartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
T1605	Enalapril	Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1615	Irbesartan	Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T1645	Ramipril	Ramipril is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.
T1940	BTB06584	BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising ...
T2270	Trans-Tranilast	Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indication...
T2318	LCZ696	LCZ696 is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.
T2322	Fimasartan	Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fima...
T2400	Candesartan Cilexetil	Candesartan Cilexetil is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal...
T2531	Eprosartan Mesylate	Eprosartan is a competitive and reversible Angiotensin II Receptor Blocker.
T3064	VTP-27999	VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
T3178	BIBS 39	BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
T3281	Delapril Hydrochloride	Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhi...
T3461	Losartan Carboxylic Acid	EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, ...
T6067	PD123319	PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist.
T6133	Remodelin hydrobromide	Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
T6219	Azilsartan Medoxomil	Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults w...
T6340	Enalaprilat Dihydrate	Enalaprilat（IC50=1.94 nM） is a potent angiotensin-converting enzyme (ACE) inhibitor.
T6444	Cilazapril Monohydrate	Cilazapril Monohydrate is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
T6486	Enalapril Maleate	Enalapril Maleate， an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension,chronic heart failure , and diabetic nephro...
T6542	Imidapril HCl	Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
T6595	Moexipril HCl	Moexipril HCl is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart f...
T6698	Temocapril HCl	Temocapril HCl, the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
T6716	Valsartan	Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
T7040	Angiotensin II human	Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I con...
T4431	EMA401	EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyper...
T5030	Zofenopril (calcium)	Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metaboli...
T5701	OPHIOPOGONIN D	Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
T5964	Olmesartan	Olmesartan is an Angiotensin II Type I receptor antagonist. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil,and has antihyperte...
T5796	Plantainoside D	Plantainoside D shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vit...
T5824	Angiotensin IV	Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.
T7339	Angiotensin 1-7	Angiotensin 1-7, also known as Ang-(1-7), is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0....
T7354	H-Val-Pro-Pro-OH	H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).
T7668	VTP-27999 TFA	VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
T7686	Ramiprilat	Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T7743	ANGIOTENSIN IV TFA(12676-15-2(free base))	ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.
TQ0057	AVE 0991	AVE 0991 is a small molecular and orally active agonist of angiotensin-(1-7) receptor (IC50: 21 nM).
T7797	Tasosartan	Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).