Transferase

A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life's most important processes.

Cat. No.	Product name	CAS No.	Purity
T14375	AZD3988	892489-52-0	98%
T14375	AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11 nM , respectively.
T6937	PF-04620110	1109276-89-2	98%
T6937	PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
TN3257	7beta-Methoxyrosmanol	24703-38-6	98%
TN3257	7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.
T11396	GGTI-2418	501010-06-6	98%
T11396	GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regress...
T12426	PF-06424439	1469284-78-3	98%
T12426	PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
T13181	Tolcapone D7	T13181	98%
T13181	Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT.
T10119	3-O-Methyltolcapone	134612-80-9	98%
T10119	3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for tre...
T11491	GSK2973980A	2219321-25-0	98%
T11491	GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
T10118	3-O-Methyltolcapone D7	T10118	98%
T10118	3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a poten...
T15109	DGAT1-IN-1	1449779-49-0	98%
T15109	DGAT1-IN-1 is a potent inhibitor of DGAT1 (IC50: < 10 nM in cell lysate from Hep3B cells overexpressing human DGAT1).
T11282	FGTI-2734	1247018-19-4	98%
T11282	FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. FGTI-2734...
T40542	Sinbaglustat	441061-33-2	98%
T40542	Sinbaglustat (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administere...
T1455	Nialamide	51-12-7	98%
T1455	Nialamide is an MAO inhibitor that is used as an antidepressive agent.
T6365	A 922500	959122-11-3	98%
T6365	A922500 is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferases, hERG, and a panel o...
T16398	Opicapone	923287-50-7	98%
T16398	Opicapone reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research ...
T2678	LB42708	226929-39-1	98%
T2678	LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
T8489	Minodronic acid monohydrate	155648-60-5	98%
T8489	Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
T6302	Lonafarnib	193275-84-2	98%
T6302	Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
T7439	3-Methoxybenzamide	5813-86-5	98%
T7439	3-Methoxybenzamide is a competitive inhibitor of poly(ADP-ribose) synthetase.
T1599L	Ibandronate sodium	138844-81-2	98%
T1599L	Ibandronate Sodium is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.