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Search Results for "flt"

Targets

Libraries

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Compounds

Cat No. Product Name
T4261 BPR1J-097 hydrochloride (1327167-19-0(free base)) FLT
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
T12555 PROTAC FLT-3 degrader 1 Others
PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-prolifera...
T39818 Desmorpholinyl Quizartinib-PEG2-COOH
Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quiz...
T25168 Boc-ypgflt(O-tbu) Boc-tyr-pro-gly-phe-leu-thr(O-t-Bu)
Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.
T61977 FLT3/D835Y-IN-1
FLT3/D835Y-IN-1 (compound 13a) is a orally active, and selective inhibitor of FLT3 and FLT3/D835Y, with IC50s of 0.26 nM...
T61415 FLT3/ITD-IN-1
FLT3/ITD-IN-1 (Compound 1) is a potent FLT3 internal tandem duplications ( FLT3-ITD ) inhibitor with IC 50 values of 38....
T61101 FLT3-IN-13
FLT3-IN-13 (compound 20) is a potent and effective antileukemic topoisomerase II and FLT3 dual inhibitor with IC 50 valu...
T2272 BPR1J-097 BPR1J097 FLT
BPR1J-097 is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3...
T4053 AST 487 NVP-AST 487 FLT , c-RET , VEGFR , c-Kit , Bcr-Abl
AST 487 is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also ca...
T5466 Tyrosine kinase-IN-1 FLT , FGFR , VEGFR , PDGFR
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM,...
T15542 Hypothemycin Others
Hypothemycin is a fungal polyketide and is a multikinase inhibitor (Kis: 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 μM, and 8...
T8326 BMS-2 FLT , c-Met/HGFR , VEGFR
BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.
T6720 Vatalanib dihydrochloride CGP-79787 dihydrochloride , ZK-222584 dihydrochloride , Vatalanib 2HCl , Vatalanib (PTK787) 2HCl , PTK787 dihydrochloride , CGP-797870 dihydrochloride VEGFR , Apoptosis , PDGFR
Vatalanib (PTK787) (IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fo...
T37426 FIIN-1
Potent, irreversible FGFR inhibitor (Kd values are 2.8, 5.4, 6.9 and 120 nM for FGFR1, FGFR3, FGFR2 and FGFR4 respective...
T1836 AZD2932 FLT , VEGFR , c-Kit , PDGFR
AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.
T19689 Raluridine DRG-0215 , FddClUrd , FCU , 935U-83 , BW-935U-83
Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited v...
T8496 MAZ51 Apoptosis , VEGFR
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
T6092 Sapitinib AZD-8931 EGFR
AZD8931, a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effe...
T1754 ZM 306416 CB 676475 VEGFR , Bcr-Abl , Src
ZM 306416, a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
T2624 OSI-930 OSI 930 FLT , c-Fms , Raf , Apoptosis , VEGFR , CSF-1R , Src , c-Kit
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets ca...
BPR1J-097 hydrochloride (1327167-19-0(free base))
T4261
synonym:
Target:
PROTAC FLT-3 degrader 1
T12555
synonym:
Target:
Desmorpholinyl Quizartinib-PEG2-COOH
T39818
synonym:
Target:
Boc-ypgflt(O-tbu)
T25168
synonym: Boc-tyr-pro-gly-phe-leu-thr(O-t-Bu)
Target:
FLT3/D835Y-IN-1
T61977
synonym:
Target:
FLT3/ITD-IN-1
T61415
synonym:
Target:
FLT3-IN-13
T61101
synonym:
Target:
BPR1J-097
T2272
synonym: BPR1J097
Target:
AST 487
T4053
synonym: NVP-AST 487
Target:
Tyrosine kinase-IN-1
T5466
synonym:
Target:
Hypothemycin
T15542
synonym:
Target:
BMS-2
T8326
synonym:
Target:
Vatalanib dihydrochloride
T6720
synonym: CGP-79787 dihydrochloride , ZK-222584 dihydrochloride , Vatalanib 2HCl , Vatalanib (PTK787) 2HCl , PTK787 dihydrochloride , CGP-797870 dihydrochloride
Target:
FIIN-1
T37426
synonym:
Target:
AZD2932
T1836
synonym:
Target:
Raluridine
T19689
synonym: DRG-0215 , FddClUrd , FCU , 935U-83 , BW-935U-83
Target:
MAZ51
T8496
synonym:
Target:
Sapitinib
T6092
synonym: AZD-8931
Target:
ZM 306416
T1754
synonym: CB 676475
Target:
OSI-930
T2624
synonym: OSI 930
Target:
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