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Search Result

Search Results for " flt "

Targets

FLT

Compounds

Cat No. Product Name
T12555 PROTAC FLT-3 degrader 1 Others
PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-prolifera...
T72407 C-Met/MEK1/Flt-3-IN-1
Antiproliferative against-3 shows a prominent activity against Hela (IC 50 = 0.21 µM), A549 (IC 50 = 0.39 µM), and MCF-...
T11299 FLT3-IN-4 FLT3 inhibitor 9u FLT
FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating...
T27011 CHMFL-FLT3-122 CHMFL FLT3 122 FLT
CHMFL-FLT3-122 is a potent and orally available FLT3 kinase inhibitor used to treat FLT3-ITD positive acute myeloid leuk...
T1938 FLT3-IN-2 FLT
FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).
T11298 FLT3-IN-3 FLT
FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.
T11300 FLT3-IN-6 Others
FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM.
T24067 Flt3 Inhibitor IV Flt3 Inhibitor-IV,Flt3-IN-IV
Flt3 Inhibitor IV is a potent ATP-competitive Flt3 inhibitor.
T36819 Ac-FLTD-CMK Caspase
Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases...
T8984 FLTX1 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding...
T9856 FLT3-IN-10 2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl- FLT
FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for ...
T64104 JAK2/FLT3-IN-1 TFA
JAK2/FLT3-IN-1 (TFA) is an orally active dual inhibitor of JAK2/FLT3 that exhibits anticancer effects, acting on JAK2 (I...
T63127 PDGFRα/FLT3-ITD-IN-3
PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/F...
T63274 FLT3/ITD-IN-2
FLT3/ITD-IN-2 is a potent inhibitor of FLT3-ITD and is able to act on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and ...
T62260 FLT3-IN-11
FLT3-IN-11 (compound 30) is an orally active, potent and selective inhibitor of FLT3 kinase, acting on wild-type FLT3 (I...
T63174 FLT3-IN-17
FLT3-IN-17 is an FAK inhibitor (IC50: 12 nM). FLT3-IN-17 inhibits the activity of CYPs and FLT3 mutants and has an IC50 ...
T62412 FLT3-IN-12
FLT3-IN-12 is a selective, potent, orally active FLT3 kinase inhibitor that acts on FLT3-WT (IC50: 1.48 nM) and FLT3-D83...
T62607 FLT3-IN-15
FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50...
T61415 FLT3/ITD-IN-1
FLT3/ITD-IN-1 (Compound 1) is a highly potent inhibitor of FLT3 internal tandem duplications (FLT3-ITD). It exhibits rem...
T61101 FLT3-IN-13
FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic c...
PROTAC FLT-3 degrader 1
T12555
synonym:
Target:
c-Met/MEK1/Flt-3-IN-1
T72407
synonym:
Target:
FLT3-IN-4
T11299
synonym: FLT3 inhibitor 9u
Target:
CHMFL-FLT3-122
T27011
synonym: CHMFL FLT3 122
Target:
FLT3-IN-2
T1938
synonym:
Target:
FLT3-IN-3
T11298
synonym:
Target:
FLT3-IN-6
T11300
synonym:
Target:
Flt3 Inhibitor IV
T24067
synonym: Flt3 Inhibitor-IV,Flt3-IN-IV
Target:
Ac-FLTD-CMK
T36819
synonym:
Target:
FLTX1
T8984
synonym:
Target:
FLT3-IN-10
T9856
synonym: 2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-
Target:
JAK2/FLT3-IN-1 TFA
T64104
synonym:
Target:
PDGFRα/FLT3-ITD-IN-3
T63127
synonym:
Target:
FLT3/ITD-IN-2
T63274
synonym:
Target:
FLT3-IN-11
T62260
synonym:
Target:
FLT3-IN-17
T63174
synonym:
Target:
FLT3-IN-12
T62412
synonym:
Target:
FLT3-IN-15
T62607
synonym:
Target:
FLT3/ITD-IN-1
T61415
synonym:
Target:
FLT3-IN-13
T61101
synonym:
Target:
1 2 3
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