Search Result

Search Results for "flt"

Targets

Libraries

Anti-Hypertension Compound Library Anti-Obesity Compound Library Anti-Cancer Metabolism Compound Library The Yao nationality medicine Library

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Compounds

Cat No.	Product Name
T4261	BPR1J-097 hydrochloride (1327167-19-0(free base))		FLT
	BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.		FLT
T12555	PROTAC FLT-3 degrader 1		Others
	PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-prolifera...		Others
T39818	Desmorpholinyl Quizartinib-PEG2-COOH
	Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quiz...
T25168	Boc-ypgflt(O-tbu)	Boc-tyr-pro-gly-phe-leu-thr(O-t-Bu)
	Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.
T61977	FLT3/D835Y-IN-1
	FLT3/D835Y-IN-1 (compound 13a) is a orally active, and selective inhibitor of FLT3 and FLT3/D835Y, with IC50s of 0.26 nM...
T61415	FLT3/ITD-IN-1
	FLT3/ITD-IN-1 (Compound 1) is a potent FLT3 internal tandem duplications ( FLT3-ITD ) inhibitor with IC 50 values of 38....
T61101	FLT3-IN-13
	FLT3-IN-13 (compound 20) is a potent and effective antileukemic topoisomerase II and FLT3 dual inhibitor with IC 50 valu...
T2272	BPR1J-097	BPR1J097	FLT
	BPR1J-097 is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3...		FLT
T4053	AST 487	NVP-AST 487	FLT , c-RET , VEGFR , c-Kit , Bcr-Abl
	AST 487 is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also ca...		FLT , c-RET , VEGFR , c-Kit , Bcr-Abl
T5466	Tyrosine kinase-IN-1		FLT , FGFR , VEGFR , PDGFR
	Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM,...		FLT , FGFR , VEGFR , PDGFR
T15542	Hypothemycin		Others
	Hypothemycin is a fungal polyketide and is a multikinase inhibitor (Kis: 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 μM, and 8...		Others
T8326	BMS-2		FLT , c-Met/HGFR , VEGFR
	BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.		FLT , c-Met/HGFR , VEGFR
T6720	Vatalanib dihydrochloride	CGP-79787 dihydrochloride , ZK-222584 dihydrochloride , Vatalanib 2HCl , Vatalanib (PTK787) 2HCl , PTK787 dihydrochloride , CGP-797870 dihydrochloride	VEGFR , Apoptosis , PDGFR
	Vatalanib (PTK787) (IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fo...		VEGFR , Apoptosis , PDGFR
T37426	FIIN-1
	Potent, irreversible FGFR inhibitor (Kd values are 2.8, 5.4, 6.9 and 120 nM for FGFR1, FGFR3, FGFR2 and FGFR4 respective...
T1836	AZD2932		FLT , VEGFR , c-Kit , PDGFR
	AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.		FLT , VEGFR , c-Kit , PDGFR
T19689	Raluridine	DRG-0215 , FddClUrd , FCU , 935U-83 , BW-935U-83
	Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited v...
T8496	MAZ51		Apoptosis , VEGFR
	MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.		Apoptosis , VEGFR
T6092	Sapitinib	AZD-8931	EGFR
	AZD8931, a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effe...		EGFR
T1754	ZM 306416	CB 676475	VEGFR , Bcr-Abl , Src
	ZM 306416, a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).		VEGFR , Bcr-Abl , Src
T2624	OSI-930	OSI 930	FLT , c-Fms , Raf , Apoptosis , VEGFR , CSF-1R , Src , c-Kit
	OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets ca...