T12555 |
PROTAC FLT-3 degrader 1
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Others
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PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-prolifera... |
T72407 |
C-Met/MEK1/Flt-3-IN-1
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Antiproliferative against-3 shows a prominent activity against Hela (IC 50 = 0.21 µM), A549 (IC 50 = 0.39 µM), and MCF-... |
T11299 |
FLT3-IN-4
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FLT3 inhibitor 9u |
FLT
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FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating... |
T27011 |
CHMFL-FLT3-122
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CHMFL FLT3 122 |
FLT
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CHMFL-FLT3-122 is a potent and orally available FLT3 kinase inhibitor used to treat FLT3-ITD positive acute myeloid leuk... |
T1938 |
FLT3-IN-2
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FLT
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FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM). |
T11298 |
FLT3-IN-3
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FLT
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FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively. |
T11300 |
FLT3-IN-6
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Others
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FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM. |
T24067 |
Flt3 Inhibitor IV
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Flt3 Inhibitor-IV,Flt3-IN-IV |
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Flt3 Inhibitor IV is a potent ATP-competitive Flt3 inhibitor. |
T36819 |
Ac-FLTD-CMK
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Caspase
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Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases... |
T8984 |
FLTX1
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Estrogen Receptor/ERR
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Estrogen/progestogen Receptor
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FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding... |
T9856 |
FLT3-IN-10
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2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl- |
FLT
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FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for ... |
T64104 |
JAK2/FLT3-IN-1 TFA
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JAK2/FLT3-IN-1 (TFA) is an orally active dual inhibitor of JAK2/FLT3 that exhibits anticancer effects, acting on JAK2 (I... |
T63127 |
PDGFRα/FLT3-ITD-IN-3
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PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/F... |
T63274 |
FLT3/ITD-IN-2
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FLT3/ITD-IN-2 is a potent inhibitor of FLT3-ITD and is able to act on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and ... |
T62260 |
FLT3-IN-11
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FLT3-IN-11 (compound 30) is an orally active, potent and selective inhibitor of FLT3 kinase, acting on wild-type FLT3 (I... |
T63174 |
FLT3-IN-17
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FLT3-IN-17 is an FAK inhibitor (IC50: 12 nM). FLT3-IN-17 inhibits the activity of CYPs and FLT3 mutants and has an IC50 ... |
T62412 |
FLT3-IN-12
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FLT3-IN-12 is a selective, potent, orally active FLT3 kinase inhibitor that acts on FLT3-WT (IC50: 1.48 nM) and FLT3-D83... |
T62607 |
FLT3-IN-15
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FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50... |
T61415 |
FLT3/ITD-IN-1
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FLT3/ITD-IN-1 (Compound 1) is a highly potent inhibitor of FLT3 internal tandem duplications (FLT3-ITD). It exhibits rem... |
T61101 |
FLT3-IN-13
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FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic c... |