Search Result

Search Results for " nod "

Targets

NOD-like Receptor (NLR) NOD NOD-like Receptor (NLR) NOD

Compounds

103

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T3587	NOD-IN-1	Compound 4	NOD-like Receptor (NLR) , NOD
	NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.		NOD-like Receptor (NLR) , NOD
T15052	Dapansutrile		NOD-like Receptor (NLR) , NOD
	Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.		NOD-like Receptor (NLR) , NOD
T13375	YQ128		IL Receptor , NOD-like Receptor (NLR) , NOD , Interleukin
	YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T4217	INF39		NOD-like Receptor (NLR) , NOD
	INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.		NOD-like Receptor (NLR) , NOD
T4164	CY-09	CY 09	NOD-like Receptor (NLR) , NOD
	CY-09 is an NLRP3 inhibitor.		NOD-like Receptor (NLR) , NOD
T8828	CP 424174		IL Receptor
	CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.		IL Receptor
T16159	Muramyl dipeptide	MDP	NOD
	Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation...		NOD
T38361	GSK717		IL Receptor , NOD
	GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...		IL Receptor , NOD
T3701	MCC950	CP-456773	NOD
	CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and...		NOD
T6591	Nodinitib-1	ML130,CID-1088438	TNF , NOD-like Receptor (NLR) , NOD
	Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.		TNF , NOD-like Receptor (NLR) , NOD
T6454	CORM-3	CORM3	Others , NF-κB , NOD-like Receptor (NLR)
	CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.		Others , NF-κB , NOD-like Receptor (NLR)
T28178	NLRP3-IN-9	INF-4E,INF 4E,INF4E	NOD
	NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ...		NOD
T1404	Stavudine	d4T,Sanilvudine,BMY-27857,NSC 163661	Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , NOD-like Receptor (NLR) , Reverse Transcriptase , Autophagy
	Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
T2131	Articaine hydrochloride	Ultracaine,Articaine HCl,Hoe-045	Sodium Channel
	Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.		Sodium Channel
T6887	MCC950 sodium	CRID3 sodium salt,CP-456773,CP-456773 sodium,MCC950	NOD-like Receptor (NLR) , NOD
	MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs). MCC950 sodium has no effect on other inflammatory vesicles such as AIM2...		NOD-like Receptor (NLR) , NOD
T3230	NLRP3-IN-2	5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I	NOD-like Receptor (NLR) , NOD
	NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting i...		NOD-like Receptor (NLR) , NOD
T9222	Emlenoflast	MCC7840	NOD-like Receptor (NLR) , NOD
	Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.		NOD-like Receptor (NLR) , NOD
T7417	Avatrombopag	YM477,AKR-501,E5501	Thrombin , Thrombopoietin Receptor
	Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.		Thrombin , Thrombopoietin Receptor
T3601	Benodanil	Calirus	Antifungal
	Benodanil (Calirus) is a kind of fungicide.		Antifungal
T1364	7-Aminodeacetoxycephalosporanic acid	7-ADCA,Cephalexin Impurity B,Cefalexine EP IMpurity B,Deacetoxycephalosporanic Acid,7-Aminodesacetoxycephalosporanic acid	Antibiotic
	7-Aminodeacetoxycephalosporanic acid (Cefalexine EP IMpurity B) is used as an antibiotic.		Antibiotic
T0628	Iminodibenzyl		Others
	Iminodibenzyl is used for the intermediates of antiepileptic drug carbamazepine.		Others
T15719	Latanoprostene bunod	LBN,NCX116	Others
	Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o...		Others
T8436	Minodronic acid	Phosphonicacid,(1-hydroxy-2-imidazo(1,2-a)pyridin-3-ylethylidene)bis-,ONO-5920,YM-529	Apoptosis , P2X Receptor
	Minodronic acid(YM-529) is a P2X2/3 receptor antagonist with anticancer activity, directly or indirectly inhibiting the proliferation of cancer cells and inducing apoptosis. Minodronic acid has been shown to inhibit the ...		Apoptosis , P2X Receptor
T9516	Binodenoson	WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos	Adenosine Receptor
	Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres...		Adenosine Receptor
T8489	Minodronic acid monohydrate		Transferase
	Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.		Transferase
T0996	Ethynodiol diacetate	Ethynodiol acetate,8080 CB	Estrogen/progestogen Receptor , Progesterone Receptor
	Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive.		Estrogen/progestogen Receptor , Progesterone Receptor
T13507	4,4'-Iminodiphenol	Leucoindophenol	Estrogen/progestogen Receptor
	4,4'-Iminodiphenol (Leucoindophenol) is an inactive estrogen receptor ligand with a diphenylamine backbone.		Estrogen/progestogen Receptor
T16335	Nonaethylene glycol monododecyl ether	Nonaoxyethylene monododecyl ether,Polidocanol	Others
	Nonaethylene glycol monododecyl ether (Polidocanol) is a nonionic surfactant and polyethylene glycol (PEG) detergent. It can be used to form initial coalesced O/W emulsion droplets and for protein separation and purifica...		Others
T68872	Cinodine hydrochloride
	Cinodine hydrochloride is a glycocinnamoylspermidine antibiotic; gyrase inhibitor found in Nocardia.
T69147	Cinodine (free base)
	Cinodine (free base) is a glycocinnamoylspermidine antibiotic; gyrase inhibitor found in Nocardia.
T36908	Bimatoprost grenod	15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α
	Bimatoprost grenod(15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2α.1It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically adm...
T68327	Dexnafenodone Free Base
	Dexnafenodone Free Base is a potent inhibitor of noradrenaline, and to a lesser degree of serotonin reuptake, induced changes in the pattern of sleep which are comparable to those of non‐sedating tricyclic antidepressant...
T79141	Mosnodenvir	JNJ-1802	Virus Protease
	Mosnodenvir (JNJ-1802), a pan-serotype dengue antiviral agent, exhibits picomolar to low nanomolar in vitro activity with a high barrier to resistance and is safe and well-tolerated in murine models [1] [2]. It functions...		Virus Protease
T27156	Dexnafenodone Hydrochloride	LU43706,LU 43706,Dexnafenodone HCl,LU-43706
	Dexnafenodone Hydrochloride is an adrenergic receptor antagonist and serotonin uptake inhibitor.
T23662	Aganodine	Aganodin
	Aganodine is a guanidine that activates presynaptic imidazoline receptors. Aganodine inhibits the presynaptic release of norepinephrine through its agonism at imidazoline receptors.
T72115	5-Iminodaunorubicin hydrochloride	盐酸5-亚氨基柔红霉素
	5-Iminodaunorubicin hydrochloride, a quinone-modified anthracycline, maintains antitumor efficacy. It induces concealed DNA strand breaks within cancer cells, mediated by protein interactions.
T80237	NODAGA-LM3
	NODAGA-LM3, when labeled with ^68Ga, serves as a PET imaging agent. As an SSTR2 antagonist, ^68Ga-NODAGA-LM3 is utilized for the visualization of SSTR-positive paragangliomas [1] [2].
T36540	Nodusmicin
	Nodusmicin is a macrolide antibiotic. It has activity against antibiotic-susceptible and -resistant S. aureus with MIC values of 125, 250, and 250 μg/ml for UC-76, UC-6685, and UC-6690 strains, respectively.
TF0036	Pentaethylene Glycol Monodecyl Ether (C10E5)
	Pentaethylene Glycol Monodecyl Ether (C10E5) is a useful organic compound for research related to life sciences. The catalog number is TF0036 and the CAS number is 23244-49-7.
T34458	Ryanodol
	Ryanodol is a complex diterpenoid that modulates intracellular calcium-ion release at ryanodine receptors, ion channels critical for skeletal and cardiac muscle excitation-contraction coupling and synaptic transmission.
TF0030	Hexaethylene Glycol Monodecyl Ether (C10E6)
	Hexaethylene Glycol Monodecyl Ether (C10E6) is a useful organic compound for research related to life sciences. The catalog number is TF0030 and the CAS number is 5168-89-8.
T72473	NOD1/2 antagonist-1
	NOD1/2 Antagonist-1 is a potent dual inhibitor of nucleotide-binding oligomerization domain-like receptors 1 and 2 (NOD1/2), displaying inhibitory concentrations (IC50) of 1.13 μM for NOD1 and 0.77 μM for NOD2. It exhibi...
T71967	Fmoc-12-aminododecanoic acid
	Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected un...
T126258	Ethyl ganoderate J
	Ethyl ganoderate J is a useful organic compound for research related to life sciences and the catalog number is T126258.
T123854	Daphnodorin B
	Daphnodorin B is a useful organic compound for research related to life sciences and the catalog number is T123854.
T123920	7-Oxoganoderic acid Z
	7-Oxoganoderic acid Z is a useful organic compound for research related to life sciences. The catalog number is T123920 and the CAS number is 929248-72-6.
T124467	Vernodalol
	Vernodalol is a useful organic compound for research related to life sciences. The catalog number is T124467 and the CAS number is 65388-17-2.
T14967	Cimlanod	BMS-986231,CXL-1427	Others
	Cimlanod is a second-generation Nitroxyl (HNO) donor for heart failure with positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod delivers HNO via pH-dependent chemical breakdown when exposed to the...		Others
T30465	Bis(2-methylpropyl)phosphinodithioic acid	J663.879A,Diisobutyl dithiophosphinate,Diisobutyldithiophosphinic acid
	Bis(2-methylpropyl)phosphinodithioic acid is a bioactive chemical.
T72467	5-Iminodaunorubicin	5-亚氨基柔红霉素
	5-Iminodaunorubicin, a quinone-modified anthracycline, maintains antitumor activity by inducing concealed DNA strand breaks within cancer cells' proteins.

Compounds

NOD-IN-1

T3587

Synonym: Compound 4

Target: NOD-like Receptor (NLR), NOD

Dapansutrile

T15052

Synonym:

Target: NOD-like Receptor (NLR), NOD

YQ128

T13375

Synonym:

Target: IL Receptor, NOD-like Receptor (NLR), NOD, Interleukin

INF39

T4217

Synonym:

Target: NOD-like Receptor (NLR), NOD

CY-09

T4164

Synonym: CY 09

Target: NOD-like Receptor (NLR), NOD

Target: IL Receptor, NOD

Synonym: ML130,CID-1088438

Target: TNF, NOD-like Receptor (NLR), NOD

CORM-3

T6454

Synonym: CORM3

Target: Others, NF-κB, NOD-like Receptor (NLR)

NLRP3-IN-9

T28178

Synonym: INF-4E,INF 4E,INF4E

Target: NOD

Stavudine

T1404

Synonym: d4T,Sanilvudine,BMY-27857,NSC 163661

Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, NOD-like Receptor (NLR), Reverse Transcriptase, Autophagy

Articaine hydrochloride

T2131

Synonym: Ultracaine,Articaine HCl,Hoe-045

Target: Sodium Channel

MCC950 sodium

T6887

Synonym: CRID3 sodium salt,CP-456773,CP-456773 sodium,MCC950

Target: NOD-like Receptor (NLR), NOD

NLRP3-IN-2

T3230

Synonym: 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I

Target: NOD-like Receptor (NLR), NOD

Emlenoflast

T9222

Synonym: MCC7840

Target: NOD-like Receptor (NLR), NOD

Avatrombopag

T7417

Synonym: YM477,AKR-501,E5501

Target: Thrombin, Thrombopoietin Receptor

7-Aminodeacetoxycephalosporanic acid

T1364

Synonym: 7-ADCA,Cephalexin Impurity B,Cefalexine EP IMpurity B,Deacetoxycephalosporanic Acid,7-Aminodesacetoxycephalosporanic acid

Synonym: Phosphonicacid,(1-hydroxy-2-imidazo(1,2-a)pyridin-3-ylethylidene)bis-,ONO-5920,YM-529

Target: Apoptosis, P2X Receptor

Binodenoson

T9516

Synonym: WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos

Target: Adenosine Receptor

Minodronic acid monohydrate

Synonym: Ethynodiol acetate,8080 CB

Target: Estrogen/progestogen Receptor, Progesterone Receptor

4,4'-Iminodiphenol

T13507

Synonym: Leucoindophenol

Target: Estrogen/progestogen Receptor

Nonaethylene glycol monododecyl ether

T16335

Synonym: Nonaoxyethylene monododecyl ether,Polidocanol

Target: Others

Cinodine hydrochloride

Synonym: 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α

Target:

Dexnafenodone Free Base

Target: Virus Protease

Dexnafenodone Hydrochloride

T27156

Synonym: LU43706,LU 43706,Dexnafenodone HCl,LU-43706

5-Iminodaunorubicin hydrochloride

Pentaethylene Glycol Monodecyl Ether (C10E5)

Hexaethylene Glycol Monodecyl Ether (C10E6)

TF0030

Synonym:

Target:

NOD1/2 antagonist-1

T72473

Synonym:

Target:

Fmoc-12-aminododecanoic acid

7-Oxoganoderic acid Z

Synonym: BMS-986231,CXL-1427

Target: Others

Bis(2-methylpropyl)phosphinodithioic acid

T30465

Synonym: J663.879A,Diisobutyl dithiophosphinate,Diisobutyldithiophosphinic acid

Cat No.	Product Name	Synonyms	Targets
T6S1256	Ruscogenin		NOS , NF-κB , NOD-like Receptor (NLR)
	1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ...		NOS , NF-κB , NOD-like Receptor (NLR)
T0772	Troxerutin	Trihydroxyethylrutin	NOD-like Receptor (NLR)
	Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.		NOD-like Receptor (NLR)
TQ0165	Arglabin	(+)-Arglabin	NOD-like Receptor (NLR) , Transferase , NOD , Autophagy
	Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.		NOD-like Receptor (NLR) , Transferase , NOD , Autophagy
T4S0350	Licochalcone B		Beta Amyloid , Others
	1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...		Beta Amyloid , Others
T3092	Nigericin sodium salt		Potassium Channel , NOD-like Receptor (NLR) , Antibacterial , Antibiotic , NOD
	Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-...
T2893	Muscone	3-Methylcyclopentadecanone,Methylexaltone	MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
	Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T5247	Trimethylamine N-oxide dihydrate	TMANO Dihydrate	Others , Endogenous Metabolite
	Trimethylamine N-oxide dihydrate (TMANO Dihydrate), a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.		Others , Endogenous Metabolite
TN1658	Ganoderenic acid D		Apoptosis , Others
	Ganoderenic acid D is a natural product isolated from the effective compounds of Ganoderma lucidum extract (GLE). Ganoderenic acid D induces cell cycle arrest and apoptosis and inhibits the proliferation of cancer cells.		Apoptosis , Others
T2S1120	Ganoderenic acid B		P-gp
	Ganoderenic acid B, a natural product derived from Ganoderma lucidum, can work by inhibiting the transport function of ABCB1 and enhancing the cytotoxicity of chemotherapy drugs against AbCB1-mediated multidrug resistant...		P-gp
TN4661	Nodosin		IL Receptor , Autophagy
	Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp...		IL Receptor , Autophagy
T4S0544	Furanodienone		Apoptosis , HER
	1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependen...		Apoptosis , HER
TN1553	Deacetyl ganoderic acid F		Others
	Deacetyl ganoderic acid F (DeGA F), a triterpenoid extracted from Ganoderma lucidum, inhibits lipopolysaccharide (LPS)-induced inflammation in vitro and in vivo.		Others
T11363	Ganoderic acid F		Others
	Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium si...		Others
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
T5S1133	Ganoderic acid D		Apoptosis , Sirtuin
	1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 micr...		Apoptosis , Sirtuin
TN1656	Ganoderenic acid A		Others
	Ganoderenic acid A has a potent hepatoprotective, and cytotoxic effects, it shows inhibitory activity on human aldose reductase in vitro.		Others
T5S1131	Ganoderic acid C6		Others
	1. Ganoderic acid C6 has antinociceptive activity.		Others
T3S1149	Ganoderic acid G		Others
	Ganoderic acid G is isolated from the surface of Ganoderma lucidum tube layer.		Others
TN1651	Furanodiene		Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp
	Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
T5259	Glycochenodeoxycholic acid sodium salt	GCDCA,Sodium glycochenodeoxycholate	Apoptosis , Others , Endogenous Metabolite
	Glycochenodeoxycholic acid sodium salt (GCDCA) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environmen...		Apoptosis , Others , Endogenous Metabolite
T3875	CLINODISIDE A		Others
	Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate.		Others
T5S1413	Nodakenetin	Prangeferol,(-)-Prangeferol,Nodakenitin	Others
	1. Nodakenetin ((-)-Prangeferol) has clinical efficacy.		Others
TN1219	20-Hydroxyganoderic acid G
	20-Hydroxyganoderic acid G is a lanosterane triterpenoid obtained from the ethanolic extract of Ganoderma curtisii (Ganoderma curtisii) cotyledons. 20-Hydroxyganoderic Acid G inhibited LPS-activated BV-2 microglia, with ...
TN1664	Ganoderic acid H		NF-κB , DNA/RNA Synthesis , CDK
	Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting in the down-regulation of expression of Cdk4.		NF-κB , DNA/RNA Synthesis , CDK
T3872	Nodakenin	(+)-Marmesinin	AChE
	Nodakenin ((+)-Marmesinin) is a compound with anti-allergic and anti-inflammatory activities.		AChE
TN1059	Ganoderic acid B		IL Receptor , HIV Protease , JAK , STAT
	Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has an...		IL Receptor , HIV Protease , JAK , STAT
T0847	Chenodeoxycholic acid	CDCA,Chenodiol	Potassium Channel , FXR , Endogenous Metabolite , Autophagy
	Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as ...		Potassium Channel , FXR , Endogenous Metabolite , Autophagy
T4588	Glycochenodeoxycholic Acid	Glycine chenodeoxycholate,Chenodeoxycholylglycine,GCDCA,Glycochenodeoxycholate,Lithocholylglycine	Apoptosis , Endogenous Metabolite
	Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid ...		Apoptosis , Endogenous Metabolite
T6S1141	Ganoderic acid A		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
	1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis a...		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
TN1661	Ganoderic acid C2		Reductase , Histamine Receptor , Immunology/Inflammation related
	Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.
T40373	Ganoderic acid ε
	Ganoderic acid ε, a naturally occurring terpenoid, is extracted from the Fungus Ganoderma lucidum. This compound possesses an ED 50 value of 12.2 μg/mL, as demonstrated in its impact on Meth-A tumor cells.
TN1061	Ganoderol B		Androgen Receptor
	Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy throu...		Androgen Receptor
TN6473	6'-Feruloylnodakenin
	6'-Feruloylnodakenin is a natural product for research related to life sciences. The catalog number is TN6473 and the CAS number is 131623-14-8.
TN4101	Ganoderenic acid H		Others
	Ganoderenic acid H is one compound of triterpenoids isolated from Ganoderma lucidum, triterpenoids exhibit a broad spectrum of anti-cancer properties, including anti-proliferative, anti-metastatic and anti-angiogenic act...		Others
TN4105	Ganoderic acid T-Q		Others
	Ganoderic acid T-Q and TR are two inhibitors of H5N1 and H1N1 NAs.		Others
TN4107	Ganoderic acid X		ERK , Mdm2 , MAPK , Caspase , Topoisomerase , JNK , p53
	Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.		ERK , Mdm2 , MAPK , Caspase , Topoisomerase , JNK , p53
T83155	Agonodepside B
	Agonodepside B is a chemical compound isolated from the filamentous fungus strain F7524, which is nonsporulating [1].
T82035	Isofuranodienone
	Please provide the sentence that includes the chemical compound '24268-42-6' so that I can assist you in rewriting it. Without the original sentence, I'm unable to offer a revised version.
T81657	Nodakenetin-Glucose-malonic acid
	Nodakenetin-Glucose-malonic acid is a natural compound [1].
T25445	Ganoderiol B
	Ganoderiol B is a moderately active HIV-1 PR inhibitor (IC50: 0.17-0.23 mM).
T75630	Ganoderic acid Mf
	Ganoderic acid Mf, an antitumor triterpenoid, selectively induces apoptosis in cancer cells through a mitochondria-mediated pathway while demonstrating high selectivity between normal and cancer cells. It also arrests th...
T75562	Ganoderic acid GS-1
	Ganoderic acid GS-1, an extensively oxygenated lanostane-type triterpenoid, exhibits anti-HIV-1 protease activities, displaying an IC50 value of 58 μM [1].
T75629	Ganoderic acid Mk
	Ganoderic acid Mk (GA-Mk), a triterpenoid acid derived from Ganoderma lucidum mycelia, exhibits potent anti-proliferative properties and can induce apoptosis in HeLa cells through a mitochondria-mediated pathway, making ...
T12787	Ryanodine		Others
	Ryanodine, a diterpenoid poison derived from Ryania speciosa, acts as a modulator of the ryanodine receptor, which is permeable to cells. Depending on its concentration, ryanodine can either stimulate or inhibit Ca2+ rel...		Others
T65749	Iminodiacetic acid
	Iminodiacetic acid is a natural product for research related to life sciences. The catalog number is T65749 and the CAS number is 142-73-4.
TN5983	Methyl ganoderenate D
	Methyl ganoderenate D is a natural product for research related to life sciences. The catalog number is TN5983 and the CAS number is 748136-03-0.
TN1669	Ganoderlactone D		Others
	Ganoderlactone D is a natural product		Others
TMA1008	Ganoderic acid S		Others
	A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the t...		Others
TMA0986	Ganoderenic acid F		Others
	Ganoderenic acid F is a natural product for research related to life sciences. The catalog number is TMA0986 and the CAS number is 120462-47-7.		Others
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Natural Products

Ruscogenin

T6S1256

Synonym:

Target: NOS, NF-κB, NOD-like Receptor (NLR)

Troxerutin

T0772

Synonym: Trihydroxyethylrutin

Target: NOD-like Receptor (NLR)

Arglabin

TQ0165

Synonym: (+)-Arglabin

Target: NOD-like Receptor (NLR), Transferase, NOD, Autophagy

Licochalcone B

T4S0350

Synonym:

Target: Beta Amyloid, Others

Nigericin sodium salt

T3092

Synonym:

Target: Potassium Channel, NOD-like Receptor (NLR), Antibacterial, Antibiotic, NOD

Muscone

T2893

Synonym: 3-Methylcyclopentadecanone,Methylexaltone

Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin

Trimethylamine N-oxide dihydrate

T5247

Synonym: TMANO Dihydrate

Target: Others, Endogenous Metabolite

Ganoderenic acid D

TN1658

Synonym:

Target: Apoptosis, Others

Target: IL Receptor, Autophagy

Furanodienone

T4S0544

Synonym:

Target: Apoptosis, HER

Deacetyl ganoderic acid F

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Ganoderic acid D

T5S1133

Synonym:

Target: Apoptosis, Sirtuin

Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

Glycochenodeoxycholic acid sodium salt

T5259

Synonym: GCDCA,Sodium glycochenodeoxycholate

Target: Apoptosis, Others, Endogenous Metabolite

Synonym: Prangeferol,(-)-Prangeferol,Nodakenitin

Target: Others

20-Hydroxyganoderic acid G

Target: NF-κB, DNA/RNA Synthesis, CDK

Nodakenin

T3872

Synonym: (+)-Marmesinin

Target: IL Receptor, HIV Protease, JAK, STAT

Chenodeoxycholic acid

T0847

Synonym: CDCA,Chenodiol

Target: Potassium Channel, FXR, Endogenous Metabolite, Autophagy

Glycochenodeoxycholic Acid

T4588

Synonym: Glycine chenodeoxycholate,Chenodeoxycholylglycine,GCDCA,Glycochenodeoxycholate,Lithocholylglycine

Target: Apoptosis, Endogenous Metabolite

Ganoderic acid A

T6S1141

Synonym:

Target: Apoptosis, NF-κB, Endogenous Metabolite, Autophagy

Ganoderic acid C2

TN1661

Synonym:

Target: Reductase, Histamine Receptor, Immunology/Inflammation related

Target: Androgen Receptor

Target: ERK, Mdm2, MAPK, Caspase, Topoisomerase, JNK, p53

Nodakenetin-Glucose-malonic acid

Methyl ganoderenate D

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00336	Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His)	SIV	HEK293

TMPH-00288	Adrenodoxin reductase Protein, Bovine, Recombinant (His)	Bovine	Yeast
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam...
TMPH-00766	LZ-8 Protein, Ganoderma lucidum, Recombinant (His & Myc)	Ganoderma lucidum	E. coli

TMPH-00220	Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 th...
TMPH-00287	Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)	Bovine	E. coli
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam...
TMPH-00456	Cyn d 1 Protein, Cynodon dactylon, Recombinant (His & Myc)	Cynodon dactylon	E. coli
	Cyn d 1 Protein, Cynodon dactylon, Recombinant (His & Myc) is expressed in E. coli.
TMPY-00323	Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)	HCV	E. coli
	HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B...
TMPY-00328	Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His)	SIV	HEK293

TMPH-03089	SCP Protein, Penaeus monodon, Recombinant (His & SUMO)	Penaeus monodon	E. coli
	SCP Protein, Penaeus monodon, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00289	NOD2 Protein, Bovine, Recombinant (His & KSI)	Bovine	E. coli
	Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, ...
TMPH-03509	Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO)	SIV	E. coli
	Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by...
TMPY-00331	Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His)	SIV	HEK293

TMPH-03088	Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO)	Penaeus monodon	E. coli
	Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO) is expressed in E. coli.