ring

Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is the deuterium substitute for Niacin and is used to track Niacin metabolism in the body.

Ezetimibe Ring-Open Impurity-d4 is a deuterated compound of Ezetimibe Ring-Open Impurity. Ezetimibe Ring-Open Impurity has a CAS number of 1197811-72-5.

3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.

3,3',5-Triiodothyronine-(tyrosine ring-13C6) hydrochloride is the 13C labeled compound of 3,3',5-Triiodothyronine hydrochloride.

3,3'-DICHLOROBENZIDINE-d6 (RINGS-d6) is a deuterated compound of 3,3'-DICHLOROBENZIDINE. 3,3'-DICHLOROBENZIDINE has a CAS number of 91-94-1.

Carbamazepine-10,11-epoxide-d10 (rings-d10) is a deuterated compound of Carbamazepine-10,11-epoxide. Carbamazepine-10,11-epoxide has a CAS number of 36507-30-9. Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine[1][2].It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively[1].Carbamazepine 10,11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent[3].

Naringenin-d4 is a deuterated compound of Naringenin. Naringenin has a CAS number of 480-41-1. Naringenin is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA.

Sulbactam-d2 is a deuterated compound of Sulbactam. Sulbactam has a CAS number of 68373-14-8. Sulbactam is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.

Maprotiline-d5 Hydrochloride is a deuterated compound of Maprotiline Hydrochloride. Maprotiline Hydrochloride has a CAS number of 10347-81-6. Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

2-Naphthol-d8 is a deuterated compound of 2-Naphthol. 2-Naphthol has a CAS number of 135-19-3. 2-Naphthol is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring.

Lamivudine-13C-d2 the 13C and deuterated compound of Lamivudine. Lamivudine has a CAS number of 134678-17-4. Lamivudine is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.