TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
T11968 |
MCL-1/BCL-2-IN-1
|
T11968
|
98%
|
|
MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3.18 μM, respectively [1].
|
T16694 |
Pyridoclax
|
1651890-44-6
|
98%
|
|
Pyridoclax is an inhibitor of potential Mcl-1.
|
T16089 |
MK-0674
|
887781-62-6
|
98%
|
|
MK-0674 is an effective and selective cathepsin K inhibitor (IC50: 0.4 nM). It also displays 1156, 1465, 11857, and 243 fold selectivity over Cat B, Cat F, Cat L...
|
TN3653 |
Cimidahurinine
|
142542-89-0
|
98%
|
|
Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity...
|
TN3708 |
Coronarin D
|
119188-37-3
|
98%
|
|
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
|
TN4490 |
Manassantin B
|
88497-88-5
|
98%
|
|
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV ...
|
TN2149 |
Reynosin
|
28254-53-7
|
98%
|
|
Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reci...
|
T10434L |
AZD-5991 Racemate
|
2143010-83-5
|
98%
|
|
AZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is an Mcl-1 inhibitor (IC50: <3 nM in FRET assay).
|
TMA0153 |
Safflor Yellow A
|
85532-77-0
|
98%
|
|
Safflor Yellow A protects cultured rat cardiomyocytes against A/R injury, maybe via inhibiting cellular oxidative stress and apoptosis.
|
TN3618 |
Cedrin
|
75513-81-4
|
98%
|
|
Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidative s...
|
TN2691 |
2',3'-Dehydrosalannol
|
97411-50-2
|
98%
|
|
2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits ca...
|
T10577 |
BM 957
|
1391107-54-2
|
98%
|
|
BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: 5.4 and 6.0 nM).
|
TN3681 |
Clerosterol
|
2364-23-0
|
98%
|
|
Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. Clerosterol exerts its cy...
|
T13454 |
(S)-Purvalanol B
|
T13454
|
98%
|
|
(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is a cyclin-dependent kinase inhibitor.
|
TN4999 |
Serratenediol
|
2239-24-9
|
98%
|
|
Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects be...
|
T12629L |
MIK665
|
1799631-75-6
|
98%
|
|
MIK665 (S-64315) has an inhibitory effect on myeloid leukemia.
|
T13337 |
WEHI-539 hydrochloride
|
2070018-33-4
|
98%
|
|
WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM).
|
TN2191 |
Scutebarbatine A
|
176520-13-1
|
98%
|
|
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspa...
|
TN3931 |
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
|
57719-81-0
|
98%
|
|
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular ...
|