T14574 |
Bimosiamose
|
187269-40-5
|
98%
|
|
Bimosiamose has anti-inflammatory effects[1]. Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-...
|
T6657 |
SB273005
|
205678-31-5
|
98%
|
|
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
|
T14573 |
Bimosiamose disodium
|
187269-60-9
|
98%
|
|
Bimosiamose disodium has anti-inflammatory effects[1]. Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM...
|
T6806 |
Cilengitide TFA
|
199807-35-7
|
98%
|
|
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectiv...
|
T16100 |
Balamapimod
|
863029-99-6
|
98%
|
|
Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.
|
T13478 |
β-glycosidase-IN-1
|
176485-27-1
|
98%
|
|
β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.
|
T9914 |
Vedolizumab
|
943609-66-3
|
98%
|
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.
|
T14558 |
BI-1950
|
1159724-42-1
|
98%
|
|
BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor and the LFA-1 is an essential component in normal immune system function an...
|
TP2148 |
LXW7 TFA (1313004-77-1 free base)
|
TP2148
|
98%
|
|
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect. LXW7 has a high binding affinity to αvβ3...
|
T8726 |
Cyclo(RGDyK)
|
217099-14-4
|
98%
|
|
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
|
T13473L |
αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
|
T13473L
|
98%
|
|
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).
|
T21868 |
BIO-1211
|
187735-94-0
|
98%
|
|
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).
|
TP1879L1 |
P11 acetate
|
TP1879L1
|
98%
|
|
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).
|
T29089 |
Valategrast hydrochloride
|
828271-96-1
|
98%
|
|
Valategrast hydrochloride, a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.
|
T12177 |
Natalizumab
|
189261-10-7
|
98%
|
|
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.
|
T0342 |
Carvedilol phosphate hemihydrate
|
610309-89-2
|
98%
|
|
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intri...
|
TP1474 |
LXW7
|
1313004-77-1
|
98%
|
|
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (EC...
|
TP1330 |
Cyclo(RADfK)
|
756500-23-9
|
98%
|
|
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.Cyclo(RADfK) is a neg...
|
T7570 |
RGD peptide (GRGDNP)
|
114681-65-1
|
98%
|
|
RGD peptide GRGDNP(2TFA) is a integrin-ligand interactions inhibitor.
|
T23796 |
BIRT-377
|
213211-10-0
|
98%
|
|
BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 nM). BIRT-377 inhibits the production of IL-2 and can be used i...
|