T10208 |
A-69412
|
123606-23-5
|
98%
|
|
A-69412 is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other in...
|
T25737 |
Linetastine
|
159776-68-8
|
98%
|
|
Linetastine is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of...
|
T68037L |
CBS-1114 HCl
|
33244-00-7
|
98%
|
|
CBS-1114 HCl is a 5-lipoxygenase inhibitor and an anti-inflammatory compound in a good eye-permeable model.CBS-1114 HCl maintains and improves cardiac function, ...
|
T62606 |
ALOX15-IN-2
|
2764818-23-5
|
98%
|
|
ALOX15-IN-2 is a potent inhibitor of ALOX15 linoleate oxygenase activity, inhibiting the oxidation of linoleic acid (LA) and arachidonic acid (AA), the immediate...
|
T34624 |
Setileuton
|
910656-27-8
|
98%
|
|
Setileuton is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.
|
T77288 |
KKII5
|
6381-55-1
|
98%
|
|
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of s...
|
T68173 |
ZD-2138
|
140841-32-3
|
98%
|
|
ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-...
|
T37974 |
(S)-Coriolic acid
|
29623-28-7
|
98%
|
|
(S)-Coriolic acid is an important intracellular signaling agent, generated by the reaction of linoleic acid with plant and mammalian lipoxygenases, and is involv...
|
T27026 |
CJ-13,610
|
179420-17-8
|
98%
|
|
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expr...
|
T10719 |
CCT365623 hydrochloride
|
2126136-98-7
|
98%
|
|
CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.
|
TN2688 |
2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone
|
33900-74-2
|
98%
|
|
2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone is a natural product obtained from Parinari hypochrysea (Chrysobalanaceae). 2,3,4'-Trihydroxy-3',5'-dimethoxypropi...
|
T10151 |
5-Lipoxygenase-In-1
|
125235-15-6
|
98%
|
|
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor extracted from patent EP 331232 A2.
|
T11196 |
Enazadrem
|
107361-33-1
|
98%
|
|
Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
|
TN1871 |
Ligustroside
|
35897-92-8
|
98%
|
|
Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustrosid...
|
TN5174 |
Trichosanatine
|
169626-16-8
|
98%
|
|
Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine...
|
TL0014 |
Pinusolide
|
31685-80-0
|
98%
|
|
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a...
|
T10438 |
AZD 4407
|
166882-70-8
|
98%
|
|
AZD 4407 is a potent inhibitor of 5-lipoxygenase.
|
TN4783 |
Picralinal
|
20045-06-1
|
98%
|
|
Picralinal has anti-inflammatory and analgesic effects.
|
T4571 |
Balsalazide
|
80573-04-2
|
98%
|
|
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
|
TN5020 |
(+/-)-Sigmoidin A
|
176046-04-1
|
98%
|
|
Sigmoidin A has moderate antioxidant, antimicrobial and anti-inflammatory activity.
|