Search Result

Search Results for "pdgfr"

Targets

Libraries

FDA-Approved Kinase Inhibitor Library Kinase Inhibitor Library

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Compounds

Cat No.	Product Name
T60108	PDGFR Tyrosine Kinase Inhibitor III	PDGF Receptor Tyrosine Kinase Inhibitor III	PDGFR
	PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III), a multikinase inhibitor, inhibits PDG...		PDGFR
T60226	CT52923		PDGFR
	CT52923 is a selective, orally active platelet-derived growth factor receptor (PDGFR) antagonist. CT52923 also is an ATP...		PDGFR
T0520	Lenvatinib	E7080	VEGFR , FGFR , c-RET , PDGFR , c-Kit
	Lenvatinib is a Kinase Inhibitor. The mechanism of action of lenvatinib is as a Receptor Tyrosine Kinase Inhibitor.		VEGFR , FGFR , c-RET , PDGFR , c-Kit
T6996	SU 5402	SU5402	VEGFR , FGFR , PDGFR
	SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, F...		VEGFR , FGFR , PDGFR
TQ0059	Ilorasertib	ABT-348	FLT , c-RET , VEGFR , Aurora Kinase , PDGFR
	Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (I...		FLT , c-RET , VEGFR , Aurora Kinase , PDGFR
T6920	ON123300		c-RET , FGFR , JAK , AMPK , Src , PDGFR , CDK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM...		c-RET , FGFR , JAK , AMPK , Src , PDGFR , CDK
T41003	KG5		FLT , Raf , c-Kit , PDGFR
	KG5 is a dual allosteric inhibitor of PDGFRβ and B-Raf with a Kd of 520 nM and 300 nM for PDGFRβ and PDGFRα. KG5 inhibit...		FLT , Raf , c-Kit , PDGFR
T4315	Ki20227		CSF-1R , VEGFR , c-Fms , c-Kit , PDGFR
	Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR...		CSF-1R , VEGFR , c-Fms , c-Kit , PDGFR
T23418	Tandutinib (MLN518) HCl		Others
	Tandutinib is an effective antagonist for FLT3, platelet-derived growth factor receptor (PDGFR), and c-Kit. Tandutinib p...		Others
T40504	N-Desmethyl imatinib mesylate	Norimatinib mesylate , ImatinibmetaboliteN-Desmethylimatinibmesylate
	N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target ...
T11640	Imatinib-d8	STI571 D8 , CGP-57148B D8	Others
	Imatinib D8 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that inhibit...		Others
T11639	Imatinib D4	STI571 D4 , CGP-57148B D4	Others
	Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selecti...		Others
T29542	AC708	AC-708 , AC 708
	AC708 is a small molecule CSF1R inhibitor that effectively inhibits CSF1R phosphorylation mediated by CSF-1 (IC50 = 26 n...
TQ0003L	740 Y-P(TFA)(1236188-16-1 free base)	740YPDGFR(TFA) , 740 Y-P(TFA) , PDGFR 740Y-P(TFA)	PI3K
	740 Y-P(TFA) is a potent and cell-permeable activator of PI3K.		PI3K
T14055	5Z-7-Oxozeaenol	LL-Z 1640-2 , L783279 , FR148083	MAPK , MEK , FLT , VEGFR , PDGFR , Antibiotic , Src
	5Z-7-Oxozeaenol, a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inh...		MAPK , MEK , FLT , VEGFR , PDGFR , Antibiotic , Src
T62872	PDGFR-IN-1
	PDGFR-IN-1 (compound 7m) is an orally active PDGFR (platelet-derived growth factor receptor) inhibitor that acts on PDGF...
T3570	SU4312	NSC 86429 , SU 4312	VEGFR , PDGFR
	SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0....		VEGFR , PDGFR
T6230	Imatinib	STI571 , ST-1571 , CGP057148B	SARS-CoV , Bcr-Abl , PDGFR , c-Kit , Autophagy
	matinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit (IC50: 600/100/100 nM).		SARS-CoV , Bcr-Abl , PDGFR , c-Kit , Autophagy
T1621	Imatinib Mesylate	ST-1571 Mesylate , CGP-57148B , STI-571	Autophagy , c-Kit , PDGFR , Bcr-Abl
	Imatinib mesylate is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM...		Autophagy , c-Kit , PDGFR , Bcr-Abl
T14137	AG 1295		PDGFR
	AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG1295 abolishes autop...		PDGFR