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Search Results for " pdgfr "

Targets

122

Compounds

3

Natural Products

30

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T60108 PDGFR Tyrosine Kinase Inhibitor III PDGF Receptor Tyrosine Kinase Inhibitor III PDGFR
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF...
TQ0003 740 Y-P 740YPDGFR,PDGFR 740Y-P PI3K , Autophagy
740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.
T4332 C-Kit-IN-1 PDGFR inhibitor 1,DCC-2618 c-Met/HGFR , c-Kit
c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
T62872 PDGFR-IN-1
PDGFR-IN-1 (compound 7m) is an orally active PDGFR (platelet-derived growth factor receptor) inhibitor that acts on PDGFRα (IC50: 2.4 nM) and PDGFRβ (IC50: 0.9 nM). PDGFR-IN-1 exhibits strong anti-tumour effects and low ...
TQ0003L1 740 Y-P acetate PDGFR 740Y-P Acetate,740YPDGFR acetate,740 Y-P acetate(1236188-16-1 Free base) PI3K
740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-terminal SH2 structural domains of p85, but not to GST alone.
TQ0003L 740 Y-P(TFA)(1236188-16-1 free base) PDGFR 740Y-P(TFA),740 Y-P(TFA),740YPDGFR(TFA) PI3K
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
T6091 CP-673451 VEGFR , PDGFR , c-Kit
CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiogenic receptors.
T14137 AG 1295 PDGFR
AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG1295 abolishes autophosphorylation of the PDGFR. But it can not affects the autophosphorylation of the EGF receptor[1][2...
T16975 TAK-593 VEGFR , PDGFR
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).
T6932 PD168393 Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.
T5109 Avapritinib BLU-285 PDGFR , c-Kit
Avapritinib (BLU-285) is a dual inhibitor of the mutant KIT receptor (KIT D816V, IC50: 0.27 nM) and PDGFRα (PDGFRα D842V, IC50: 0.24 nM).
T4320 Flumatinib HHGV678 Bcr-Abl , PDGFR , c-Kit
Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.
T5466 Tyrosine kinase-IN-1 VEGFR , FGFR , FLT , PDGFR
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively)
T6996 SU 5402 SU5402 VEGFR , FGFR , PDGFR
SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
T7945 SU14813 VEGFR , PDGFR , c-Kit
SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).
T2415 PP121 Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).
T8900 Seralutinib GB002 PDGFR
Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.
TQ0235 AC710 FLT , PDGFR , c-Kit
AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).
T6166 Telatinib Bay 57-9352 VEGFR , PDGFR , c-Kit
Telatinib (Bay 57-9352) is an effective inhibitor of VEGFR2/3, c-Kit, and PDGFRα. The IC50s of Telatinib forVEGFR2/3, c-Kit and PDGFRα are 6 nM/4 nM, 1 nM, and 15 nM, respectively.
T3570 SU4312 SU 4312,NSC 86429 VEGFR , PDGFR
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotox...
T9030 SU4984 FGFR , IGF-1R , PDGFR
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
T10157 Regorafénib N-oxyde (M2) Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).
T6350 CHIR-124 CHIR124,CHIR 124 Apoptosis , GSK-3 , FLT , Chk , PDGFR , Src
CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.
T3476 JI-101 CGI-1842,JI 101 VEGFR , PDGFR , Ephrin Receptor
JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), platelet derived growth factor receptor β (PDGFR-β), and ephrin type-B receptor 4 (EphB4).
T1452 Axitinib AG-013736 VEGFR , PDGFR , c-Kit
Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.
T2500 Cediranib AZD2171,NSC-732208 VEGFR , FLT , PDGFR , c-Kit , Autophagy
Cediranib (AZD2171) (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit...
T13178 Toceranib PHA 291639E,SU11654 VEGFR , PDGFR , c-Kit
Toceranib (PHA 291639E) phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively), has antitu...
T1777 Nintedanib BIBF 1120,Intedanib VEGFR , FGFR , FLT , PDGFR , Src
Nintedanib (Intedanib) is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, FGFR1-4, and PDGFRα/β, respectively).
T4191 Multi-kinase inhibitor 1 Multi-kinase inhibitor I Others , Bcr-Abl , PDGFR , c-Kit
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.
T0080 Trapidil Rocornal,Trapymine,Avantrin,Trapymin,AR-12008 PDGFR , PDE
Trapidil (Avantrin) is a coronary vasodilator agent. It was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
T1792L Regorafenib monohydrate Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect...
T6920 ON123300 FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
T0097L Pazopanib GW786034 VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...
T1836 AZD2932 VEGFR , FLT , PDGFR , c-Kit
AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.
TQ0059 Ilorasertib ABT-348 VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...
T8976 PD-089828 EGFR , FGFR , PDGFR , Src
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...
T8402 Regorafenib Hydrochloride BAY73-4506 hydrochloride Raf , VEGFR , c-RET , PDGFR , Autophagy
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
T15616 JNJ-10198409 JNJ-​10198409 PDGFR
JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, ant...
T0520 Lenvatinib E7080 VEGFR , FGFR , c-RET , PDGFR , c-Kit
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (...
T2609 Masitinib AB1010 Apoptosis , FAK , c-Fms , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Hck
Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet...
T2358 ENMD-2076 Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T2677 Crenolanib ARO 002,CP-868596 FLT , PDGFR , Autophagy
Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).
T11641 N-Desmethyl imatinib Imatinib metabolite N-Desmethyl imatinib,Norimatinib Bcr-Abl , PDGFR , c-Kit , Drug Metabolite
N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.
T41003 KG5 Raf , FLT , PDGFR , c-Kit
KG5 is a dual allosteric inhibitor of PDGFRβ and B-Raf with a Kd of 520 nM and 300 nM for PDGFRβ and PDGFRα. KG5 inhibits FLT3, KIT, and c-Raf with anticancer and antiangiogenic activities.
T8482 Ripretinib DCC-2618 Apoptosis , VEGFR , FLT , PDGFR , c-Kit
Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.
T6230 Imatinib STI571,CGP057148B,ST-1571 SARS-CoV , Bcr-Abl , PDGFR , c-Kit , Autophagy
Imatinib (STI571) is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit (IC50: 600/100/100 nM).
T0374L Sunitinib SU 11248 Apoptosis , Mitophagy , VEGFR , FLT , IRE1 , PDGFR , c-Kit , Autophagy
Sunitinib (SU 11248), a multi-targeted RTK inhibitor, is targeting PDGFRβ and VEGFR2 (Flk-1) with IC50 of 2 nM and 80 nM and also inhibits c-Kit.
T8491 Vorolanib CM082,X-82 VEGFR , PDGFR
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.
T2372 Ponatinib AP24534 VEGFR , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Autophagy
Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively).
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...

Compounds

PDGFR Tyrosine Kinase Inhibitor III
T60108
Synonym: PDGF Receptor Tyrosine Kinase Inhibitor III
Target: PDGFR
740 Y-P
TQ0003
Synonym: 740YPDGFR,PDGFR 740Y-P
Target: PI3K, Autophagy
c-Kit-IN-1
T4332
Synonym: PDGFR inhibitor 1,DCC-2618
Target: c-Met/HGFR, c-Kit
PDGFR-IN-1
T62872
Synonym:
Target:
740 Y-P acetate
TQ0003L1
Synonym: PDGFR 740Y-P Acetate,740YPDGFR acetate,740 Y-P acetate(1236188-16-1 Free base)
Target: PI3K
740 Y-P(TFA)(1236188-16-1 free base)
TQ0003L
Synonym: PDGFR 740Y-P(TFA),740 Y-P(TFA),740YPDGFR(TFA)
Target: PI3K
CP-673451
T6091
Synonym:
Target: VEGFR, PDGFR, c-Kit
AG 1295
T14137
Synonym:
Target: PDGFR
TAK-593
T16975
Synonym:
Target: VEGFR, PDGFR
PD168393
T6932
Synonym:
Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy
Avapritinib
T5109
Synonym: BLU-285
Target: PDGFR, c-Kit
Flumatinib
T4320
Synonym: HHGV678
Target: Bcr-Abl, PDGFR, c-Kit
Tyrosine kinase-IN-1
T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
SU 5402
T6996
Synonym: SU5402
Target: VEGFR, FGFR, PDGFR
SU14813
T7945
Synonym:
Target: VEGFR, PDGFR, c-Kit
PP121
T2415
Synonym:
Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck
Seralutinib
T8900
Synonym: GB002
Target: PDGFR
AC710
TQ0235
Synonym:
Target: FLT, PDGFR, c-Kit
Telatinib
T6166
Synonym: Bay 57-9352
Target: VEGFR, PDGFR, c-Kit
SU4312
T3570
Synonym: SU 4312,NSC 86429
Target: VEGFR, PDGFR
SU4984
T9030
Synonym:
Target: FGFR, IGF-1R, PDGFR
Regorafénib N-oxyde (M2)
T10157
Synonym:
Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Drug Metabolite
CHIR-124
T6350
Synonym: CHIR124,CHIR 124
Target: Apoptosis, GSK-3, FLT, Chk, PDGFR, Src
JI-101
T3476
Synonym: CGI-1842,JI 101
Target: VEGFR, PDGFR, Ephrin Receptor
Axitinib
T1452
Synonym: AG-013736
Target: VEGFR, PDGFR, c-Kit
Cediranib
T2500
Synonym: AZD2171,NSC-732208
Target: VEGFR, FLT, PDGFR, c-Kit, Autophagy
Toceranib
T13178
Synonym: PHA 291639E,SU11654
Target: VEGFR, PDGFR, c-Kit
Nintedanib
T1777
Synonym: BIBF 1120,Intedanib
Target: VEGFR, FGFR, FLT, PDGFR, Src
Multi-kinase inhibitor 1
T4191
Synonym: Multi-kinase inhibitor I
Target: Others, Bcr-Abl, PDGFR, c-Kit
Trapidil
T0080
Synonym: Rocornal,Trapymine,Avantrin,Trapymin,AR-12008
Target: PDGFR, PDE
Regorafenib monohydrate
T1792L
Synonym:
Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy
ON123300
T6920
Synonym:
Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK
Pazopanib
T0097L
Synonym: GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
AZD2932
T1836
Synonym:
Target: VEGFR, FLT, PDGFR, c-Kit
Ilorasertib
TQ0059
Synonym: ABT-348
Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase
PD-089828
T8976
Synonym:
Target: EGFR, FGFR, PDGFR, Src
Regorafenib Hydrochloride
T8402
Synonym: BAY73-4506 hydrochloride
Target: Raf, VEGFR, c-RET, PDGFR, Autophagy
JNJ-10198409
T15616
Synonym: JNJ-​10198409
Target: PDGFR
Lenvatinib
T0520
Synonym: E7080
Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit
Masitinib
T2609
Synonym: AB1010
Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck
ENMD-2076
T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
Crenolanib
T2677
Synonym: ARO 002,CP-868596
Target: FLT, PDGFR, Autophagy
N-Desmethyl imatinib
T11641
Synonym: Imatinib metabolite N-Desmethyl imatinib,Norimatinib
Target: Bcr-Abl, PDGFR, c-Kit, Drug Metabolite
KG5
T41003
Synonym:
Target: Raf, FLT, PDGFR, c-Kit
Ripretinib
T8482
Synonym: DCC-2618
Target: Apoptosis, VEGFR, FLT, PDGFR, c-Kit
Imatinib
T6230
Synonym: STI571,CGP057148B,ST-1571
Target: SARS-CoV, Bcr-Abl, PDGFR, c-Kit, Autophagy
Sunitinib
T0374L
Synonym: SU 11248
Target: Apoptosis, Mitophagy, VEGFR, FLT, IRE1, PDGFR, c-Kit, Autophagy
Vorolanib
T8491
Synonym: CM082,X-82
Target: VEGFR, PDGFR
Ponatinib
T2372
Synonym: AP24534
Target: VEGFR, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Autophagy
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
1 2 3
Cat No. Product Name Synonyms Targets
T2734 Sennoside B PDGFR
Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.
TN1969 N-(p-Coumaroyl) serotonin PDGFR
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving...
TN2354 Methylnissolin 3-Hydroxy-9,10-dimethoxyptercarpan ERK , PDGFR
Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01139 PDGFRA Protein, Human, Recombinant (His) Human HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPK-01050 PDGF R beta/CD140b Protein, Canine, Recombinant (His) Canine HEK293
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct c...
TMPK-00422 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct c...
TMPK-00421 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) Human HEK293
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct c...
TMPK-00481 PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity ...
TMPY-04937 PDGFRB Protein, Human, Recombinant (His), Biotinylated Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05358 PDGFRB Protein, Human, Recombinant Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01207 PDGFRB Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05497 PDGFRB Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPK-00943 PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPK-00420 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPY-05608 PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPK-00419 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) Human HEK293
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPY-00900 PDGFRA Protein, Human, Recombinant (hFc) Human HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-05789 PDGFRA Protein, Mouse, Recombinant (hFc) Mouse HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-05787 PDGFRA Protein, Mouse, Recombinant (His) Mouse HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-03590 PDGFRB Protein, Rhesus, Recombinant (His) Rhesus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03474 PDGFRB Protein, Rat, Recombinant (hFc) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03140 PDGFRB Protein, Rat, Recombinant (His) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00385 PDGFRB Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03825 PDGFRA Protein, Rat, Recombinant (His) Rat HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-03919 PDGFRA Protein, Rat, Recombinant (hFc) Rat HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-06921 PDGFRA Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-04976 PDGFC Protein, Mouse, Recombinant (His) Mouse Yeast
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPK-01178 PDGFD Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, including proliferation, migration, adhesion and tube format...
TMPY-00898 PDGFC Protein, Human, Recombinant (hFc) Human HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-02815 PDGFC Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-02251 PDGFC Protein, Mouse, Recombinant (hFc) Mouse HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-00269 PDGFC Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-04484 ACK1 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
ACK1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. This downstream effector of CDC42 mediates CDC42-dependent cell mig...
PDGFRA Protein, Human, Recombinant (His)
TMPY-01139
Species: Human
Expression System: HEK293
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
TMPK-01050
Species: Canine
Expression System: HEK293
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00422
Species: Human
Expression System: HEK293
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
TMPK-00421
Species: Human
Expression System: HEK293
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
TMPK-00481
Species: Cynomolgus
Expression System: HEK293
PDGFRB Protein, Human, Recombinant (His), Biotinylated
TMPY-04937
Species: Human
Expression System: HEK293
PDGFRB Protein, Human, Recombinant
TMPY-05358
Species: Human
Expression System: HEK293
PDGFRB Protein, Human, Recombinant (His)
TMPY-01207
Species: Human
Expression System: HEK293
PDGFRB Protein, Human, Recombinant (hFc)
TMPY-05497
Species: Human
Expression System: HEK293
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
TMPK-00943
Species: Cynomolgus
Expression System: HEK293
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00420
Species: Human
Expression System: HEK293
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05608
Species: Human
Expression System: HEK293
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
TMPK-00419
Species: Human
Expression System: HEK293
PDGFRA Protein, Human, Recombinant (hFc)
TMPY-00900
Species: Human
Expression System: HEK293
PDGFRA Protein, Mouse, Recombinant (hFc)
TMPY-05789
Species: Mouse
Expression System: HEK293
PDGFRA Protein, Mouse, Recombinant (His)
TMPY-05787
Species: Mouse
Expression System: HEK293
PDGFRB Protein, Rhesus, Recombinant (His)
TMPY-03590
Species: Rhesus
Expression System: HEK293
PDGFRB Protein, Rat, Recombinant (hFc)
TMPY-03474
Species: Rat
Expression System: HEK293
PDGFRB Protein, Rat, Recombinant (His)
TMPY-03140
Species: Rat
Expression System: HEK293
PDGFRB Protein, Rhesus, Recombinant (hFc)
TMPY-00385
Species: Rhesus
Expression System: HEK293
PDGFRA Protein, Rat, Recombinant (His)
TMPY-03825
Species: Rat
Expression System: HEK293
PDGFRA Protein, Rat, Recombinant (hFc)
TMPY-03919
Species: Rat
Expression System: HEK293
PDGFRA Protein, Cynomolgus, Recombinant (His)
TMPY-06921
Species: Cynomolgus
Expression System: HEK293
PDGFC Protein, Mouse, Recombinant (His)
TMPY-04976
Species: Mouse
Expression System: Yeast
PDGFD Protein, Cynomolgus, Recombinant (His)
TMPK-01178
Species: Cynomolgus
Expression System: HEK293
PDGFC Protein, Human, Recombinant (hFc)
TMPY-00898
Species: Human
Expression System: HEK293
PDGFC Protein, Human, Recombinant (His)
TMPY-02815
Species: Human
Expression System: Baculovirus-Insect Cells
PDGFC Protein, Mouse, Recombinant (hFc)
TMPY-02251
Species: Mouse
Expression System: HEK293
PDGFC Protein, Cynomolgus, Recombinant (hFc)
TMPY-00269
Species: Cynomolgus
Expression System: HEK293
ACK1 Protein, Human, Recombinant (GST)
TMPY-04484
Species: Human
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L1610 FDA-Approved Kinase Inhibitor Library

280 compounds
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、...
L1600 Kinase Inhibitor Library

2230 compounds
A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;
TargetMol