T60108 |
PDGFR Tyrosine Kinase Inhibitor III
|
PDGF Receptor Tyrosine Kinase Inhibitor III |
PDGFR
|
|
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III), a multikinase inhibitor, inhibits PDG... |
T60226 |
CT52923
|
|
PDGFR
|
|
CT52923 is a selective, orally active platelet-derived growth factor receptor (PDGFR) antagonist. CT52923 also is an ATP... |
T0520 |
Lenvatinib
|
E7080 |
VEGFR
,
FGFR
,
c-RET
,
PDGFR
,
c-Kit
|
|
Lenvatinib is a Kinase Inhibitor. The mechanism of action of lenvatinib is as a Receptor Tyrosine Kinase Inhibitor. |
T6996 |
SU 5402
|
SU5402 |
VEGFR
,
FGFR
,
PDGFR
|
|
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, F... |
TQ0059 |
Ilorasertib
|
ABT-348 |
FLT
,
c-RET
,
VEGFR
,
Aurora Kinase
,
PDGFR
|
|
Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (I... |
T6920 |
ON123300
|
|
c-RET
,
FGFR
,
JAK
,
AMPK
,
Src
,
PDGFR
,
CDK
|
|
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM... |
T41003 |
KG5
|
|
FLT
,
Raf
,
c-Kit
,
PDGFR
|
|
KG5 is a dual allosteric inhibitor of PDGFRβ and B-Raf with a Kd of 520 nM and 300 nM for PDGFRβ and PDGFRα. KG5 inhibit... |
T4315 |
Ki20227
|
|
CSF-1R
,
VEGFR
,
c-Fms
,
c-Kit
,
PDGFR
|
|
Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR... |
T23418 |
Tandutinib (MLN518) HCl
|
|
Others
|
|
Tandutinib is an effective antagonist for FLT3, platelet-derived growth factor receptor (PDGFR), and c-Kit. Tandutinib p... |
T40504 |
N-Desmethyl imatinib mesylate
|
Norimatinib mesylate , ImatinibmetaboliteN-Desmethylimatinibmesylate |
|
|
N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target ... |
T11640 |
Imatinib-d8
|
STI571 D8 , CGP-57148B D8 |
Others
|
|
Imatinib D8 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that inhibit... |
T11639 |
Imatinib D4
|
STI571 D4 , CGP-57148B D4 |
Others
|
|
Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selecti... |
T29542 |
AC708
|
AC-708 , AC 708 |
|
|
AC708 is a small molecule CSF1R inhibitor that effectively inhibits CSF1R phosphorylation mediated by CSF-1 (IC50 = 26 n... |
TQ0003L |
740 Y-P(TFA)(1236188-16-1 free base)
|
740YPDGFR(TFA) , 740 Y-P(TFA) , PDGFR 740Y-P(TFA) |
PI3K
|
|
740 Y-P(TFA) is a potent and cell-permeable activator of PI3K. |
T14055 |
5Z-7-Oxozeaenol
|
LL-Z 1640-2 , L783279 , FR148083 |
MAPK
,
MEK
,
FLT
,
VEGFR
,
PDGFR
,
Antibiotic
,
Src
|
|
5Z-7-Oxozeaenol, a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inh... |
T62872 |
PDGFR-IN-1
|
|
|
|
PDGFR-IN-1 (compound 7m) is an orally active PDGFR (platelet-derived growth factor receptor) inhibitor that acts on PDGF... |
T3570 |
SU4312
|
NSC 86429 , SU 4312 |
VEGFR
,
PDGFR
|
|
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.... |
T6230 |
Imatinib
|
STI571 , ST-1571 , CGP057148B |
SARS-CoV
,
Bcr-Abl
,
PDGFR
,
c-Kit
,
Autophagy
|
|
matinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit (IC50: 600/100/100 nM). |
T1621 |
Imatinib Mesylate
|
ST-1571 Mesylate , CGP-57148B , STI-571 |
Autophagy
,
c-Kit
,
PDGFR
,
Bcr-Abl
|
|
Imatinib mesylate is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM... |
T14137 |
AG 1295
|
|
PDGFR
|
|
AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG1295 abolishes autop... |