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MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.
Cat No. product name
T1455 Nialamide Nialamide is an MAO inhibitor that is used as an antidepressive agent.
T24680 PSB-1491 PSB-1491 is a selective and competitive monoamine oxidase B inhibitor.
T6651 Safinamide mesylate Safinamide Mesylate, a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
T8589 (±)-Amiflamine Amiflamine is an inhibitor of reversible MAO-A.
T7048 1,4-Naphthoquinone 1, 4-Naphthoquinone was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase...
T8907 Minaprine dihydrochloride Minaprine dihydrochloride is a reversible MAO-A inhibitor; It weakly inhibit acetylcholinesterase. Minaprine dihydrochloride is an antidepressant for treatment o...
T2741 Glycyrrhizic acid Glycyrrhizic acid is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
T24679 PSB-1434 PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
T1119 Rasagiline Rasagiline is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
T0418 Allylthiourea Allylthiourea, a metabolic inhibitor, specifically suppresses ammonia oxidation.
T5678 Lazabemide hydrochloride N-(2-Aminoethyl)-5-chlor-2-pyridincarbox is a reversible and selective mao-b inhibitor(Ki:7.9nM).
T5887 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (7- Hydroxy- 3, 4- dihydro- 2(1H) - quinolinone) is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
T1747 Tedizolid Tedizolid is an Oxazolidinone Antibacterial. The mechanism of action of tedizolid is as a Breast Cancer Resistance Protein Inhibitor.
TN1120 Osthenol Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoti...
T0235 Modaline sulfate Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to...
T5648 Purpurin Purpurin was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative a...
T5050 Selegiline hydrochloride Selegiline hydrochloride is a selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM). Monoamine oxidase (MAO) inhibitors have utility...
T0338 Minaprine Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T1549 Raloxifene hydrochloride Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estroge...
T6862 Isatin Isatin is an endogenous MAO inhibitor.
T7942 Tranylcypromine hemisulfate Tranylcypromine is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
T6962 Rasagiline Mesylate Rasagiline Mesylate is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
TN2004 Obtusin Obtusin is a natural product.
TMS1743 Salvigenin Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.
T0821 Iproniazid Phosphate Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI).
T22605 Bifemelane hydrochloride Bifemelane hydrochloride is a MAO inhibitor
T3933 Jatrorrhizine Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
T3596 TB5 TB5 is a potent, selective and reversible inhibitor of hMAO-B.
TN7057 Rosmarinate acid Rosmarinate acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively
T5470 LAZABEMIDE LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T5053 Eprobemide Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
T0300 Pargyline Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.
T18918 Azure B Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and 968 nM for recombi...
T1711 Harmine Harmine is an alkaloid isolated from seeds of Peganum harmala.
T0751 Furazolidone Furazolidone, a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,
T0966 Sennoside A Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
T0391 Linezolid Linezolid, the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including me...
T1578 Pargyline hydrochloride Pargyline hydrochloride is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
T2765 Rosmarinic acid Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive ...
T1117 Clorgyline hydrochloride Clorgyline hydrochloride, a white powder, is served as monoamine oxidase inhibitor.
T1613 Hydralazine hydrochloride Hydralazine Hydrochloride is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydra...
T2900 Paeonol Paeonol is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
T0084 Moclobemide Moclobemide is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
T3095 Tyramine Tyramine is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can ser...
T5323 Toloxatone MD 69276 (Toloxatone) is a reversible monoamine oxidase A (MAOA) inhibitor.
T50055 Milacemide Milacemide is a glycine prodrug and MAO-B inhibitor. Milacemide has been studied for its effects on human memory and as a potential treatment for the symptoms of...
T23453 Tetrindole mesylate Tetrindole mesylate is a MAO-A inhibitor.
TN2553 1-Methyl-2-undecyl-4(1H)-quinolone 1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN1705 Glycyrrhisoflavone Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase.
TN1099 Dihydroevocarpine Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
Nialamide
T1455
Nialamide is an MAO inhibitor that is used as an antidepressive agent.
PSB-1491
T24680
PSB-1491 is a selective and competitive monoamine oxidase B inhibitor.
Safinamide mesylate
T6651
Safinamide Mesylate, a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
(±)-Amiflamine
T8589
Amiflamine is an inhibitor of reversible MAO-A.
1,4-Naphthoquinone
T7048
1, 4-Naphthoquinone was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase...
Minaprine dihydrochloride
T8907
Minaprine dihydrochloride is a reversible MAO-A inhibitor; It weakly inhibit acetylcholinesterase. Minaprine dihydrochloride is an antidepressant for treatment o...
Glycyrrhizic acid
T2741
Glycyrrhizic acid is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
PSB-1434
T24679
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
Rasagiline
T1119
Rasagiline is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
Allylthiourea
T0418
Allylthiourea, a metabolic inhibitor, specifically suppresses ammonia oxidation.
Lazabemide hydrochloride
T5678
N-(2-Aminoethyl)-5-chlor-2-pyridincarbox is a reversible and selective mao-b inhibitor(Ki:7.9nM).
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
T5887
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (7- Hydroxy- 3, 4- dihydro- 2(1H) - quinolinone) is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
Tedizolid
T1747
Tedizolid is an Oxazolidinone Antibacterial. The mechanism of action of tedizolid is as a Breast Cancer Resistance Protein Inhibitor.
Osthenol
TN1120
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promot...
Modaline sulfate
T0235
Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to...
Purpurin
T5648
Purpurin was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative ...
Selegiline hydrochloride
T5050
Selegiline hydrochloride is a selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM). Monoamine oxidase (MAO) inhibitors have utili...
Minaprine
T0338
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
Raloxifene hydrochloride
T1549
Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estroge...
Isatin
T6862
Isatin is an endogenous MAO inhibitor.
Tranylcypromine hemisulfate
T7942
Tranylcypromine is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
Rasagiline Mesylate
T6962
Rasagiline Mesylate is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
Obtusin
TN2004
Obtusin is a natural product.
Salvigenin
TMS1743
Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.
Iproniazid Phosphate
T0821
Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI).
Bifemelane hydrochloride
T22605
Bifemelane hydrochloride is a MAO inhibitor
Jatrorrhizine
T3933
Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
TB5
T3596
TB5 is a potent, selective and reversible inhibitor of hMAO-B.
rosmarinate acid
TN7057
Rosmarinate acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively
LAZABEMIDE
T5470
LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
Eprobemide
T5053
Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
Pargyline
T0300
Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.
Azure B
T18918
Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and 968 nM for recombi...
Harmine
T1711
Harmine is an alkaloid isolated from seeds of Peganum harmala.
Furazolidone
T0751
Furazolidone, a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,
Sennoside A
T0966
Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
Linezolid
T0391
Linezolid, the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including me...
Pargyline hydrochloride
T1578
Pargyline hydrochloride is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
Rosmarinic acid
T2765
Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive ...
Clorgyline hydrochloride
T1117
Clorgyline hydrochloride, a white powder, is served as monoamine oxidase inhibitor.
Hydralazine hydrochloride
T1613
Hydralazine Hydrochloride is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydra...
Paeonol
T2900
Paeonol is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
Moclobemide
T0084
Moclobemide is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
Tyramine
T3095
Tyramine is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can ser...
Toloxatone
T5323
MD 69276 (Toloxatone) is a reversible monoamine oxidase A (MAOA) inhibitor.
Milacemide
T50055
Milacemide is a glycine prodrug and MAO-B inhibitor. Milacemide has been studied for its effects on human memory and as a potential treatment for the symptoms of...
Tetrindole mesylate
T23453
Tetrindole mesylate is a MAO-A inhibitor.
1-Methyl-2-undecyl-4(1H)-quinolone
TN2553
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
Glycyrrhisoflavone
TN1705
Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase.
Dihydroevocarpine
TN1099
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
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