MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.

Cat No.	product name
T1455	Nialamide	Nialamide is an MAO inhibitor that is used as an antidepressive agent.
T24680	PSB-1491	PSB-1491 is a selective and competitive monoamine oxidase B inhibitor.
T6651	Safinamide mesylate	Safinamide Mesylate, a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
T8589	(±)-Amiflamine	Amiflamine is an inhibitor of reversible MAO-A.
T7048	1,4-Naphthoquinone	1, 4-Naphthoquinone was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase...
T8907	Minaprine dihydrochloride	Minaprine dihydrochloride is a reversible MAO-A inhibitor; It weakly inhibit acetylcholinesterase. Minaprine dihydrochloride is an antidepressant for treatment o...
T2741	Glycyrrhizic acid	Glycyrrhizic acid is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
T24679	PSB-1434	PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
T1119	Rasagiline	Rasagiline is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
T0418	Allylthiourea	Allylthiourea, a metabolic inhibitor, specifically suppresses ammonia oxidation.
T5678	Lazabemide hydrochloride	N-(2-Aminoethyl)-5-chlor-2-pyridincarbox is a reversible and selective mao-b inhibitor(Ki：7.9nM).
T5887	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone	3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (7- Hydroxy- 3, 4- dihydro- 2(1H) - quinolinone) is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
T1747	Tedizolid	Tedizolid is an Oxazolidinone Antibacterial. The mechanism of action of tedizolid is as a Breast Cancer Resistance Protein Inhibitor.
TN1120	Osthenol	Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoti...
T0235	Modaline sulfate	Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to...
T5648	Purpurin	Purpurin was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative a...
T5050	Selegiline hydrochloride	Selegiline hydrochloride is a selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM). Monoamine oxidase (MAO) inhibitors have utility...
T0338	Minaprine	Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T1549	Raloxifene hydrochloride	Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estroge...
T6862	Isatin	Isatin is an endogenous MAO inhibitor.
T7942	Tranylcypromine hemisulfate	Tranylcypromine is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
T6962	Rasagiline Mesylate	Rasagiline Mesylate is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
TN2004	Obtusin	Obtusin is a natural product.
TMS1743	Salvigenin	Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.
T0821	Iproniazid Phosphate	Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI).
T22605	Bifemelane hydrochloride	Bifemelane hydrochloride is a MAO inhibitor
T3933	Jatrorrhizine	Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal act...
T3596	TB5	TB5 is a potent, selective and reversible inhibitor of hMAO-B.
TN7057	Rosmarinate acid	Rosmarinate acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively
T5470	LAZABEMIDE	LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T5053	Eprobemide	Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
T0300	Pargyline	Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.
T18918	Azure B	Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and 968 nM for recombi...
T1711	Harmine	Harmine is an alkaloid isolated from seeds of Peganum harmala.
T0751	Furazolidone	Furazolidone, a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,
T0966	Sennoside A	Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
T0391	Linezolid	Linezolid, the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including me...
T1578	Pargyline hydrochloride	Pargyline hydrochloride is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
T2765	Rosmarinic acid	Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive ...
T1117	Clorgyline hydrochloride	Clorgyline hydrochloride, a white powder, is served as monoamine oxidase inhibitor.
T1613	Hydralazine hydrochloride	Hydralazine Hydrochloride is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydra...
T2900	Paeonol	Paeonol is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
T0084	Moclobemide	Moclobemide is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
T3095	Tyramine	Tyramine is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can ser...
T5323	Toloxatone	MD 69276 (Toloxatone) is a reversible monoamine oxidase A (MAOA) inhibitor.
T50055	Milacemide	Milacemide is a glycine prodrug and MAO-B inhibitor. Milacemide has been studied for its effects on human memory and as a potential treatment for the symptoms of...
T23453	Tetrindole mesylate	Tetrindole mesylate is a MAO-A inhibitor.
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone	1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN1705	Glycyrrhisoflavone	Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase.
TN1099	Dihydroevocarpine	Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...