MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.

Cat No.	product name
T0084	Moclobemide	Moclobemide is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
T0235	Modaline sulfate	Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar ...
T0300	Pargyline	Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.
T0338	Minaprine dihydrochloride	Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T0369	Ethaverine hydrochloride	Ethaverine hydrochloride is a homologue of papaverine.
T0391	Linezolid	Linezolid, the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including ...
T0418	Allylthiourea	Allylthiourea, a metabolic inhibitor, specifically suppresses ammonia oxidation.
T0751	Furazolidone	Furazolidone, a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,
T0821	Iproniazid Phosphate	Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI).
T0966	Sennoside A	Senna is a herbal laxative that is found in garden rhubarb and green vegetables.
T1025	Tranylcypromine (2-PCPA) hydrochloride	Tranylcypromine Hydrochloride, a monoamine oxidase inhibitor, is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It...
T1117	Clorgyline hydrochloride	Clorgyline hydrochloride, a white powder, is served as monoamine oxidase inhibitor.
T1119	Rasagiline	Rasagiline is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
T1455	Nialamide	Nialamide is an MAO inhibitor that is used as an antidepressive agent.
T1549	Raloxifene hydrochloride	Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrog...
T1578	Pargyline hydrochloride	Pargyline hydrochloride is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
T1613	Hydralazine hydrochloride	Hydralazine Hydrochloride is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydr...
T1711	Harmine	Harmine is an alkaloid isolated from seeds of Peganum harmala.
T1747	Torezolid	Tedizolid is an Oxazolidinone Antibacterial. The mechanism of action of tedizolid is as a Breast Cancer Resistance Protein Inhibitor.
T2765	Rosmarinic acid	Rosmarinic acid has shown to contain antioxidant,anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive ...
T2900	Paeonol	Paeonol is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
T3095	Tyramine	Tyramine is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can se...
T3596	TB5	TB5 is a potent, selective and reversible inhibitor of hMAO-B.
T3933	Jatrorrhizine	Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal ac...
T6651	Safinamide mesylate	Safinamide Mesylate, a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
T6862	Isatin	Isatin is an endogenous MAO inhibitor.
T6962	Rasagiline Mesylate	Rasagiline Mesylate is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
T7048	1,4-Naphthoquinone	1,4-Naphthoquinone was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase...
T5050	Selegiline hydrochloride	Selegiline hydrochloride is a selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM). Monoamine oxidase (MAO) inhibitors have util...
T5053	Eprobemide	Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
T5323	MD 69276	MD 69276 (Toloxatone) is a reversible monoamine oxidase A (MAOA) inhibitor.
T5678	N-(2-Aminoethyl)-5-chlor-2-pyridincarbox	N-(2-Aminoethyl)-5-chlor-2-pyridincarbox is a reversible and selective mao-b inhibitor(Ki：7.9nM).
T5676	(Z)-SU4312	(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
T5648	Purpurin	Purpurin was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative...
T5887	3,4-Dihydro-7-hydroxy-2(1H)-quinolinone	3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (7- Hydroxy- 3, 4- dihydro- 2(1H) - quinolinone) is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
TMS1743	Salvigenin	Salvigenin is a potent inhibitor of hMAO-A(monoamine oxidases),with neuroprotective effect and antitumor cytotoxic and immunomodulatory properties.
T5470	LAZABEMIDE	LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T2741	Glycyrrhizin	Glycyrrhizic acid is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
T7942	Tranylcypromine (hemisulfate)	Tranylcypromine is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
TN1120	Osthenol	Osthenol shows antitumor-promoting activity, it also has antifungal and antibacterial activities.
TN1705	Glycyrrhisoflavone	Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase.
TN1099	Dihydroevocarpine	Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is ...
T10146	4-Hydroxyderricin	4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B inhibitor (IC50: 3.43 μM). It also mildly inhibits DB...
T15010	CR4056	CR4056 is a selective inhibitor of human recombinant MAO-A (IC50: 202.7 nM) and a ligand of the imidazoline-2 receptor (I2R) (IC50: 596 nM).
T15023	CX-157	CX-157 is a reversible monoamine oxidase-A (MAO-A) inhibitor (EC50:19.3 ng/mL).
T10617	Brofaromine	Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
T10079	MAO-IN-1	MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
T16770	Ro 41-1049 hydrochloride	Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
T8589	Amiflamine	Amiflamine is an inhibitor of reversible MAO-A.
TN2553	1-Methyl-2-undecylquinolin-4(1H)-one	1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evod...