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Mitochondrial Metabolism

Mitochondrial metabolism encompasses pathways that generate ATP to drive intracellular unfavorable energetic reactions and produce the building blocks necessary for macromolecule synthesis.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T78208 Leramistat 1642602-54-7 98%
Leramistat
Leramistat (HMC-C-01-A; MBS2320), a mitochondrial complex 1 inhibitor, plays a role in regulating cell and immune metabolism. It is effective in suppressing vari...
T78875 BTM-3528 2054998-45-5 98%
BTM-3528
BTM-3528 is a mitochondrial protease OMA1 activator that induces an overactivation of the mitochondrial integrated stress response (ISR). It promotes OMA1-depend...
T79226 AMPK activator 11 2948304-00-3 98%
AMPK activator 11
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-a...
T79476 SCAL-255 2798953-61-2 98%
SCAL-255
SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM. It impedes mitochondrial function by blocking oxygen ...
T79477 SCAL-266 2798953-78-1 98%
SCAL-266
SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM. This compound impairs mitochondrial function by blocking oxidative pho...
T7487 Speract 76901-59-2 98%
Speract
Speract is a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.
T22783 FGIN-1-43 145040-29-5 99.98%
FGIN-1-43
FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.
T9169 MPP+ iodide 36913-39-0 99.96%
MPP+ iodide
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in s...
T0938 Thiabendazole 148-79-8 99.94%
Thiabendazole
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
T8366 Mitochonic acid 5 1354707-41-7 99.91%
Mitochonic acid 5
Mitochonic acid 5 (MA-5) is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardia...
T14497 BAM 15 210302-17-3 99.89%
BAM 15
BAM 15 is an uncoupler of mitochondrial protonophore.
T5337 IACS-010759 1570496-34-2 99.83%
IACS-010759
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
T2930 α-Lipoic Acid 62-46-4 99.76%
α-Lipoic Acid
α-Lipoic Acid (Alphalipoic acid) inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hep...
T13701 Genistein 8-c-glucoside 66026-80-0 99.72%
Genistein 8-c-glucoside
Genistein 8-c-glucoside (G8CG) induces mitochondrial membrane depolarization and induces apoptosis. Genistein 8-c-glucoside (G8CG) is a natural glucoside isolate...
T77615 ND-011992 2446880-46-0 99.7%
ND-011992
ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory c...
T15373 Gboxin 2101315-36-8 99.58%
Gboxin
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
TN1586 Dihydrorotenone 6659-45-6 99.58%
Dihydrorotenone
Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
T7922 Kresoxim-Methyl 143390-89-0 99.57%
Kresoxim-Methyl
Kresoxim-methyl is a strobilurin fungicide,inhibits conidial germination of V. inaequalis isolates from apple orchards .
T15241 ER-000444793 792957-74-5 99.55%
ER-000444793
ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).
T9232 Mitochondrial fusion promoter M1 219315-22-7 99.54%
Mitochondrial fusion promoter M1
Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellula...
Leramistat
T78208
Leramistat (HMC-C-01-A; MBS2320), a mitochondrial complex 1 inhibitor, plays a role in regulating cell and immune metabolism. It is effective in suppressing vari...
BTM-3528
T78875
BTM-3528 is a mitochondrial protease OMA1 activator that induces an overactivation of the mitochondrial integrated stress response (ISR). It promotes OMA1-depend...
AMPK activator 11
T79226
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-a...
SCAL-255
T79476
SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM. It impedes mitochondrial function by blocking oxygen ...
SCAL-266
T79477
SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM. This compound impairs mitochondrial function by blocking oxidative pho...
Speract
T7487
Speract is a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.
FGIN-1-43
T22783
FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.
MPP+ iodide
T9169
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in s...
Thiabendazole
T0938
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
Mitochonic acid 5
T8366
Mitochonic acid 5 (MA-5) is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardia...
BAM 15
T14497
BAM 15 is an uncoupler of mitochondrial protonophore.
IACS-010759
T5337
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
α-Lipoic Acid
T2930
α-Lipoic Acid (Alphalipoic acid) inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hep...
Genistein 8-c-glucoside
T13701
Genistein 8-c-glucoside (G8CG) induces mitochondrial membrane depolarization and induces apoptosis. Genistein 8-c-glucoside (G8CG) is a natural glucoside isolate...
ND-011992
T77615
ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory c...
Gboxin
T15373
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
Dihydrorotenone
TN1586
Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
Kresoxim-Methyl
T7922
Kresoxim-methyl is a strobilurin fungicide,inhibits conidial germination of V. inaequalis isolates from apple orchards .
ER-000444793
T15241
ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).
Mitochondrial fusion promoter M1
T9232
Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellula...
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TargetMol