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PD-1/PD-L1

PD-1 inhibitors and PD-L1 inhibitors are a group of checkpoint inhibitor anticancer drugs that block the activity of PD-1 and PDL1 immune checkpoint proteins present on the surface of cells. Immune checkpoint inhibitors are emerging as a front-line treatment for several types of cancer.
Cat No. product name
T3146 BMS-202 PD1-PDL1 inhibitor 2 is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction, extracted from patent WO/2...
T6S0071 Fraxinellone 1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhib...
T26859 BMS-8 BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction.
T9902 Atezolizumab Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD...
T0844 Sulfamethoxypyridazine Sulfamethoxypyridazine is a sulfanilamide antibacterial agent.
T3468 Tomivosertib eFT508 is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.
T3655 BMS-1 PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand ...
T35396 Spartalizumab (anti-PD-1) Spartalizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合。PDR001可与PD-1以高亲和力结合,抑制其生物活性;MW: 145.8 KD。
T35395 Camrelizumab (anti-PD-1) Camrelizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合,具有抑制免疫检查点效果和抗肿瘤活性;MW: 146.3 KD。
T35394 Sintilimab (anti-PD-1) Sintilimab (anti-PD-1, IBI 308) 是一种全人源 IgG4 单克隆抗体,可与 T 细胞表面的PD-1结合,阻断 PD-1/PD-配体 1 (PD-L1) 通路,并重新激活 T 细胞以杀死癌细胞。
T9908 Pembrolizumab Pembrolizumab is a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to bind...
T9907 Nivolumab Nivolumab anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell ...
T9903 Avelumab Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity.
T9359 PDL-1 cpd 10 PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.
T8470 BMS-1001 BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
T10565 BMS-1001 hydrochloride BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect o...
T4696 BMS202 hydrochloride (1675203-84-5(free base)) PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. B...
T5697 BMS-1166 BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
TP1076L AUNP-12 acetate (1353563-85-5 Free base) AUNP-12 acetate是一种PD-1的多肽抑制剂,在抑制淋巴细胞增殖和效应功能上对PD-1和PD-2等效,具有免疫激活和良好的抗肿瘤活性。
BMS-202
T3146
PD1-PDL1 inhibitor 2 is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction, extracted from patent WO/2...
Fraxinellone
T6S0071
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhib...
BMS-8
T26859
BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction.
Atezolizumab
T9902
Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD...
Sulfamethoxypyridazine
T0844
Sulfamethoxypyridazine is a sulfanilamide antibacterial agent.
Tomivosertib
T3468
eFT508 is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.
BMS-1
T3655
PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand ...
Spartalizumab (anti-PD-1)
T35396
Camrelizumab (anti-PD-1)
T35395
Camrelizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合,具有抑制免疫检查点效果和抗肿瘤活性;MW: ...
Sintilimab (anti-PD-1)
T35394
Sintilimab (anti-PD-1, IBI 308) 是一种全人源 IgG4 单克隆抗体,可与 T 细胞表面的PD-1结合,阻断 PD-1/PD-配体 1 (PD-L1) 通路,并重新...
Pembrolizumab
T9908
Pembrolizumab is a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to bind...
Nivolumab
T9907
Nivolumab anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell ...
Avelumab
T9903
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity.
PDL-1 cpd 10
T9359
PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.
BMS-1001
T8470
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
BMS-1001 hydrochloride
T10565
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect o...
BMS202 hydrochloride (1675203-84-5(free base))
T4696
PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. B...
BMS-1166
T5697
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
AUNP-12 acetate (1353563-85-5 Free base)
TP1076L