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MMP

Matrix metallopeptidases (MMPs), also known as matrix metalloproteinases or matrixins, are metalloproteinases that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily.
Cat No. product name
TN1560 Dehydroeffusol Dehydroeffusol possesses anti-cancer, anxiolytic and sedative properties, it may antagonize the spasmogenic activity of various agents, and therefore, could be a...
T4S0181 Hinokiflavone Hinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre-mRNA substrates by inhibiting spli...
T1592 Acetohydroxamic acid Acetohydroxamic acid is an antagonist of the bacterial enzyme urease.
T7459 Abametapir Abametapir, a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.
T3090 Abietic Acid Abietic Acid is the primary component of resin acid isolated from rosin.
T7044 Norepinephrine Norepinephrine can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular...
T3813 20(R)-Ginsenoside Rh2 Ginsenoside Rh2 is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.
T0407 Edaravone Edaravone(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.
T3860 Isoliquiritin apioside Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced act...
T8259 Doxycycline monohydrate Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)
T2987 (-)-Epigallocatechin (-)-Epigallocatechin is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils.
T4122 TAPI-1 trifluoroacetate (171235-71-5(free base)) TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
T5680 ALOIN ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.
T4282 S-methyl-KE-298 S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from...
T4S21320 ISOGINKGETIN 1. Isoginkgetin, a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a kn...
T3388 Calycosin-7-O-β-D-glucoside Calycosin 7-O-β-D-glucopyranoside possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has antim...
T2893 Muscone Muscone is an organic compound that is the primary contributor to the odor of musk.
T2792 Glucosamine sulfate Extracted from synthetic product;Store the product in sealed, cool and dry condition
T2834 Nobiletin Nobiletin is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (...
T2787 Picroside I Picroside I, a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may...
T1687 Doxycycline Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity.
T3767 Polygalacic acid Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acet...
T2993 Cordycepin Cordycepin is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity.
T3S0640 Triolein Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
T1140 Doxycycline hydrochloride Doxycycline hydrochloride is a synthetic tetracycline derivative with similar antimicrobial activity.
T0429 Glucosamine Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Supplemental glucosamine may help to re...
T6S2140 β-Anhydroicaritin 1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover...
T2750 Ginkgolide C Ginkgolide C, a natural product, can enhance the cardiac function of rats in the body.
T6009 TAPI1 TAPI-1, an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.
T21513 Cytochalasin H Cytochalasin H is a potent inhibitor of actin incorporation into filaments.
T2980 Chondroitin sulfate Extracted from shark bone;Store the product in sealed, cool and dry condition
T7522 GI254023X GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can re...
T2967 Stigmasterol Stigmasterol is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized m...
T8961 GW280264X GW280264X is an inhibitor of ADAM17 .
T3414 Morroniside Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal ...
T2957 Arctigenin (-)-Arctigenin is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Ar...
T5S0045 Isofraxidin 1. Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective...
T1687L Doxycycline (hyclate) Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity. It is also an inhibitor of matrix metalloproteinases (MMP).
TN1928 Methyl rosmarinate Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmari...
T3729 Ethyl gallate Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependen...
T2973 Astragaloside IV Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteas...
T4115 Auraptene Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuro...
T5983 O-Phenanthroline O-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-phenanthroline prot...
T2743 Ilomastat Ilomastat (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.
T1891 NSC 405020 NSC 405020 is a noncatalytic inhibitor of MT1-MMP.
T2009 SB-3CT SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).
TN1376 α-Solanine Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
TN1093 Ginsenoside F4 Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the i...
TN2316 Xanthyletin Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
TN1998 Notoginsenoside T5 Total panax notoginsenosides (TPNS) are the main active ingredients in San-Chi, the root of(Burk) F.H. Chen, which belongs to the Araliaceae family and has been ...
Dehydroeffusol
TN1560
Dehydroeffusol possesses anti-cancer, anxiolytic and sedative properties, it may antagonize the spasmogenic activity of various agents, and therefore, could be a...
Hinokiflavone
T4S0181
Hinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre-mRNA substrates by inhibiting spli...
Acetohydroxamic acid
T1592
Acetohydroxamic acid is an antagonist of the bacterial enzyme urease.
Abametapir
T7459
Abametapir, a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.
Abietic Acid
T3090
Abietic Acid is the primary component of resin acid isolated from rosin.
Norepinephrine
T7044
Norepinephrine can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascula...
20(R)-Ginsenoside Rh2
T3813
Ginsenoside Rh2 is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.
Edaravone
T0407
Edaravone(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.
Isoliquiritin apioside
T3860
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced act...
Doxycycline monohydrate
T8259
Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)
(-)-Epigallocatechin
T2987
(-)-Epigallocatechin is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils.
TAPI-1 trifluoroacetate (171235-71-5(free base))
T4122
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
ALOIN
T5680
ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.
S-methyl-KE-298
T4282
S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from...
ISOGINKGETIN
T4S21320
1. Isoginkgetin, a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a kn...
Calycosin-7-O-β-D-glucoside
T3388
Calycosin 7-O-β-D-glucopyranoside possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has ant...
Muscone
T2893
Muscone is an organic compound that is the primary contributor to the odor of musk.
Glucosamine sulfate
T2792
Extracted from synthetic product;Store the product in sealed, cool and dry condition
Nobiletin
T2834
Nobiletin is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (...
Picroside I
T2787
Picroside I, a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may...
Doxycycline
T1687
Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity.
Polygalacic acid
T3767
Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acet...
Cordycepin
T2993
Cordycepin is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity.
Triolein
T3S0640
Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
Doxycycline hydrochloride
T1140
Doxycycline hydrochloride is a synthetic tetracycline derivative with similar antimicrobial activity.
Glucosamine
T0429
Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Supplemental glucosamine may help to re...
β-Anhydroicaritin
T6S2140
1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover...
Ginkgolide C
T2750
Ginkgolide C, a natural product, can enhance the cardiac function of rats in the body.
TAPI1
T6009
TAPI-1, an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.
Cytochalasin H
T21513
Cytochalasin H is a potent inhibitor of actin incorporation into filaments.
Chondroitin sulfate
T2980
Extracted from shark bone;Store the product in sealed, cool and dry condition
GI254023X
T7522
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can r...
Stigmasterol
T2967
Stigmasterol is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized m...
GW280264X
T8961
GW280264X is an inhibitor of ADAM17 .
Morroniside
T3414
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal ...
Arctigenin
T2957
(-)-Arctigenin is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Ar...
Isofraxidin
T5S0045
1. Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective...
Doxycycline (hyclate)
T1687L
Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity. It is also an inhibitor of matrix metalloproteinases (MMP).
Methyl rosmarinate
TN1928
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmari...
Ethyl gallate
T3729
Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependen...
Astragaloside IV
T2973
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteas...
Auraptene
T4115
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuro...
o-Phenanthroline
T5983
O-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-phenanthroline prot...
Ilomastat
T2743
Ilomastat (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.
NSC 405020
T1891
NSC 405020 is a noncatalytic inhibitor of MT1-MMP.
SB-3CT
T2009
SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).
α-Solanine
TN1376
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
Ginsenoside F4
TN1093
Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the i...
Xanthyletin
TN2316
Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
Notoginsenoside T5
TN1998
Total panax notoginsenosides (TPNS) are the main active ingredients in San-Chi, the root of(Burk) F.H. Chen, which belongs to the Araliaceae family and has been ...
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