T12082 |
MMP3 inhibitor 1
|
312930-75-9
|
98%
|
|
MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).
|
TN2075 |
Pimaric acid
|
127-27-5
|
98%
|
|
Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α±-induced human ...
|
TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN3616 |
Cedrelone
|
1254-85-9
|
98%
|
|
Cedrelone exhibits antifeedant activity, it has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fas...
|
TN1867 |
Licoricidin
|
30508-27-1
|
98%
|
|
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
|
T16137 |
MRS1177
|
183721-13-3
|
98%
|
|
MRS1177 is an effective and selective antagonist of the human Adenosine A3 receptor (hA3AR) (Ki: 0.3 nM).
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
|
T12539 |
Prinomastat hydrochloride
|
1435779-45-5
|
98%
|
|
Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with An...
|
TN1998 |
Notoginsenoside T5
|
769932-34-5
|
98%
|
|
Total panax notoginsenosides (TPNS) are the main active ingredients in San-Chi, the root of(Burk) F.H. Chen, which belongs to the Araliaceae family and has been ...
|
TN4978 |
Scutellarein-7-O-glucoside
|
26046-94-6
|
98%
|
|
Scutellarein-7-O-glucoside inhibites MMP-2 activity.
|
T3426 |
Bacoside A
|
11028-00-5
|
98%
|
|
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
|
T16986 |
Tanomastat
|
179545-77-8
|
98%
|
|
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 30...
|
TN1376 |
α-Solanine
|
20562-02-1
|
98%
|
|
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
|
T15055 |
DB04760
|
544678-85-5
|
98%
|
|
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activ...
|
TN1615 |
Epitheaflagallin 3-O-gallate
|
102067-92-5
|
98%
|
|
Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growt...
|
TN3691 |
Communic acid
|
2761-77-5
|
98%
|
|
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
|
T10597 |
BR351
|
960113-85-3
|
98%
|
|
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
|
T30531L |
BMS-561392 Formic acid
|
T30531L
|
98%
|
|
BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.
|
T12539L |
Prinomastat
|
192329-42-3
|
98%
|
|
Prinomastat inhibits MMP-2, MMP-3 and MMP-9 (Kis: 0.05 nM, 0.3 nM and 0.26 nM, respectively). Prinomastat crosses the blood-brain barrier. It also has antitumor ...
|
TN1881 |
Lucidenic acid C
|
95311-96-9
|
98%
|
|
Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
|