T22794 |
G36
|
1392487-51-2
|
98%
|
|
G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 n...
|
T11237 |
Camizestrant
|
2222844-89-3
|
98%
|
|
Camizestrant is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
|
T11098 |
Droloxifene
|
82413-20-5
|
98%
|
|
Droloxifene, a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells....
|
T11237L |
Camizestrant TFA
|
T11237L
|
98%
|
|
Camizestrant TFA is a potent and orally active antagonist of estrogen receptor (ER).
|
T60664 |
Atamestane
|
96301-34-7
|
98%
|
|
Atamestane is a competitive, irreversible inhibitor of estrogen biosynthesis, a specific aromatase inhibitor that selectively blocks estrogen biosynthesis result...
|
T11236 |
Giredestrant tartrate
|
2407529-33-1
|
98%
|
|
Giredestrant tartrate is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, ...
|
T9455 |
4-hydroxyestrone-4-methyl ether
|
58562-33-7
|
98%
|
|
4-hydroxyestrone-4-methyl ether is the methylation of 4-OHE1, which is catalyzed by COMT.
|
T6404 |
Bazedoxifene hydrochloride
|
198480-56-7
|
98%
|
|
Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectivel...
|
T6827 |
Endoxifen Z-isomer hydrochloride
|
1032008-74-4
|
98%
|
|
Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
|
TN1567 |
Delphinidin chloride
|
528-53-0
|
98%
|
|
Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of ...
|
TN3084 |
5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone
|
1353676-65-9
|
98%
|
|
5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone showed strong anti-proliferation effect on ER-positive breast cancer MCF-7 cells in vitro, with an IC50 val...
|
T9454 |
4-Hydroxyestrone
|
3131-23-5
|
98%
|
|
4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.
|
T9997 |
GLL 398
|
2077980-80-2
|
98%
|
|
GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
|
T0760 |
Cholesterol
|
57-88-5
|
98%
|
|
Cholesterol is the primary sterol in mammals. The significance of Cholesterol is becoming more appreciated in fundamental cellular processes.
|
T6306 |
Erteberel
|
533884-09-2
|
98%
|
|
LY500307 is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2.
|
T2146 |
Fulvestrant
|
129453-61-8
|
98%
|
|
Fulvestrant is a potent Estrogen Receptor antagonist (IC50: 9.4 nM).
|
T3385 |
Gypenoside XVII
|
80321-69-3
|
98%
|
|
Gypenoside XVII confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/...
|
T0384 |
Estradiol benzoate
|
50-50-0
|
98%
|
|
Estradiol Benzoate is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics...
|
TN1148 |
Isopsoralenoside
|
905954-18-9
|
98%
|
|
Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects.
|
T21387L |
Nafoxidine
|
1845-11-0
|
98%
|
|
Nafoxidine is an estrogen antagonist that has been used in the treatment of breast cancer.
|