Estrogen Receptor/ERR

The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones.There are three human estrogen related receptors:ERRα,ERRβand ERRγ .

Cat. No.	Product name	CAS No.	Purity
T22794	G36	1392487-51-2	98%
T22794	G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 n...
T11237	Camizestrant	2222844-89-3	98%
T11237	Camizestrant is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
T11098	Droloxifene	82413-20-5	98%
T11098	Droloxifene, a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells....
T11237L	Camizestrant TFA	T11237L	98%
T11237L	Camizestrant TFA is a potent and orally active antagonist of estrogen receptor (ER).
T60664	Atamestane	96301-34-7	98%
T60664	Atamestane is a competitive, irreversible inhibitor of estrogen biosynthesis, a specific aromatase inhibitor that selectively blocks estrogen biosynthesis result...
T11236	Giredestrant tartrate	2407529-33-1	98%
T11236	Giredestrant tartrate is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, ...
T9455	4-hydroxyestrone-4-methyl ether	58562-33-7	98%
T9455	4-hydroxyestrone-4-methyl ether is the methylation of 4-OHE1, which is catalyzed by COMT.
T6404	Bazedoxifene hydrochloride	198480-56-7	98%
T6404	Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectivel...
T6827	Endoxifen Z-isomer hydrochloride	1032008-74-4	98%
T6827	Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
TN1567	Delphinidin chloride	528-53-0	98%
TN1567	Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of ...
TN3084	5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone	1353676-65-9	98%
TN3084	5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone showed strong anti-proliferation effect on ER-positive breast cancer MCF-7 cells in vitro, with an IC50 val...
T9454	4-Hydroxyestrone	3131-23-5	98%
T9454	4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.
T9997	GLL 398	2077980-80-2	98%
T9997	GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
T0760	Cholesterol	57-88-5	98%
T0760	Cholesterol is the primary sterol in mammals. The significance of Cholesterol is becoming more appreciated in fundamental cellular processes.
T6306	Erteberel	533884-09-2	98%
T6306	LY500307 is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2.
T2146	Fulvestrant	129453-61-8	98%
T2146	Fulvestrant is a potent Estrogen Receptor antagonist (IC50: 9.4 nM).
T3385	Gypenoside XVII	80321-69-3	98%
T3385	Gypenoside XVII confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/...
T0384	Estradiol benzoate	50-50-0	98%
T0384	Estradiol Benzoate is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics...
TN1148	Isopsoralenoside	905954-18-9	98%
TN1148	Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects.
T21387L	Nafoxidine	1845-11-0	98%
T21387L	Nafoxidine is an estrogen antagonist that has been used in the treatment of breast cancer.