TLR

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-pass membrane-spanning receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes.

Cat. No.	Product name	CAS No.	Purity
T16870	Selgantolimod	2004677-13-6	98%
T16870	Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
T15785	LPA1 receptor antagonist 1	1396006-71-5	98%
T15785	LPA1 antagonist 1 is a highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist (IC50: 25 nM).
TN4171	Grossamide	80510-06-1	98%
TN4171	Grossamide possesses potential anti-inflammatory effects, it also has potential anti-neuroinflammatory effects against lipopolysaccharide (LPS)-induced inflammat...
T39115	ABR-238901	1638200-22-2	98%
T39115	ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products) ...
T13182	Toll-like receptor modulator	926927-42-6	98%
T13182	Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
TN5138	Teuclatriol	152110-17-3	98%
TN5138	Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-ÎºB signaling at doses of 312...
TP1938	RS 09	1449566-36-2	98%
TP1938	TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enh...
T10437	AZD8848	866269-28-5	98%
T10437	AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
T35349	CU-CPD107	2573912-32-8	98%
T35349	CU-CPD107 is a selective agonist of toll-like receptor 8 (TLR8) and also shows activation activity against ssRNA ligands. CU-CPD107 acts as an inhibitor of TLR8...
T14035	3M-011	642473-62-9	98%
T14035	3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy...
T15751	LHC-165	1258595-14-0	98%
T15751	LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
TN3587	Capillarisin	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T34249	Rabeximod	872178-65-9	98%
T34249	Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by ...
T17032	Telratolimod	1359993-59-1	98%
T17032	Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.
T13168	TLR7 agonist 1	2178156-33-5	98%
T13168	TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
T60052	BMS-905	2205846-49-5	98%
T60052	BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members. BMS-905 can be used in studies about the treatm...
T19675	SM360320	226907-52-4	98%
T19675	SM360320 is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to it...
T2S0265	Robinin	301-19-9	98%
T2S0265	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of ...
T39669	TLR7/8/9-IN-1	2180127-82-4	98%
T39669	TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
T37292	M62812	613263-00-6	98%
T37292	TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects ...