T8706 |
BC-1471
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Others
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BC-1471 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels... |
T13167 |
TLR7/8 agonist 3
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TLR
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TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8. |
T39669 |
TLR7/8/9-IN-1
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TLR
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TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM. |
T39654 |
Afimetoran
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BMS-986256 |
TLR
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Afimetoran is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune dis... |
TP1067 |
Pam3CSK4 TFA (112208-00-1 free base)
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Pam3Cys-Ser-(Lys)4 TFA , Pam3CSK4 TFA |
TLR
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Pam3CSK4 TFA is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2). |
TNU0892 |
4-Amino-1,3-dihydro-1-[(6-methyl-3-pyridinyl)methyl]-6- [(tetrahydro-2H-pyran-4-yl)methoxy]-2H-imidazo[4,5-c]-pyridin-2-one
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Drugs and Inhibitors; toll-like receptor (TLR) agonist |
T4413 |
Poseltinib
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Poseltinib, an orally active, selective and irreversible Bruton’s tyrosine kinase (BTK) inhibitor ( IC 50 =1.95 nM), wit... |
T9948 |
NecroX-7
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LC-280126 , LC28-0126 , LC28 0126 |
NADPH-oxidase
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NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as a... |
T36421 |
Immuno-Oncology Screening Library
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The Immuno-Oncology Screening Library consists of 2 plates and contains more than 90 cancer and immunology-associated co... |
T40039 |
TLR8 agonist 2
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TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC 50 of 3 nM for human TLR8. TLR8 agonist 2 shows less ac... |
T38614 |
TLR7 agonist 3
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TLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune act... |
T40040 |
TLR8 agonist 2 hydrochloride
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TLR8 agonist 2 hydrochloride is a potent and selective TLR8 agonist with an EC 50 of 3 nM for human TLR8. TLR8 agonist 2... |
T39969 |
TLR7/8 agonist 4 TFA
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TLR7/8 agonist 4 TFA (compound 41) is a potent TLR7/8 agonist. TLR7/8 agonist 4 has anti-cancer activity. |
T36629 |
Givinostat
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Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
Givinostat (... |
T39968 |
TLR7/8 agonist 4 hydroxy-PEG10-acid
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TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by us... |
T39970 |
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
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TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor ... |
T61601 |
TLR7/8 antagonist 2
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TLR7/8 antagonist 2 (Compound 15) is a potent and orally active agonist of TLR7/8 with IC 50 s of 4.9 and 0.6 nM, respec... |
T60894 |
TLR7/8 agonist 4
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TLR7/8 agonist 4 (compound 41) is a potent agonist of TLR7/8 with anti-cancer activity [1]. |
T10899 |
CU-CPT17e
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TLR
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CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9). |
T10315 |
AN-3485
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Others
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AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM). |