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Search Result

Search Results for "tlr"

Targets

TLR

Compounds

Cat No. Product Name
T8706 BC-1471 Others
BC-1471 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels...
T13167 TLR7/8 agonist 3 TLR
TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.
T39669 TLR7/8/9-IN-1 TLR
TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
T39654 Afimetoran BMS-986256 TLR
Afimetoran is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune dis...
TP1067 Pam3CSK4 TFA (112208-00-1 free base) Pam3Cys-Ser-(Lys)4 TFA , Pam3CSK4 TFA TLR
Pam3CSK4 TFA is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2).
TNU0892 4-Amino-1,3-dihydro-1-[(6-methyl-3-pyridinyl)methyl]-6-   [(tetrahydro-2H-pyran-4-yl)methoxy]-2H-imidazo[4,5-c]-pyridin-2-one
Drugs and Inhibitors; toll-like receptor (TLR) agonist
T4413 Poseltinib
Poseltinib, an orally active, selective and irreversible Bruton’s tyrosine kinase (BTK) inhibitor ( IC 50 =1.95 nM), wit...
T9948 NecroX-7 LC-280126 , LC28-0126 , LC28 0126 NADPH-oxidase
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as a...
T36421 Immuno-Oncology Screening Library
The Immuno-Oncology Screening Library consists of 2 plates and contains more than 90 cancer and immunology-associated co...
T40039 TLR8 agonist 2
TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC 50 of 3 nM for human TLR8. TLR8 agonist 2 shows less ac...
T38614 TLR7 agonist 3
TLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune act...
T40040 TLR8 agonist 2 hydrochloride
TLR8 agonist 2 hydrochloride is a potent and selective TLR8 agonist with an EC 50 of 3 nM for human TLR8. TLR8 agonist 2...
T39969 TLR7/8 agonist 4 TFA
TLR7/8 agonist 4 TFA (compound 41) is a potent TLR7/8 agonist. TLR7/8 agonist 4 has anti-cancer activity.
T36629 Givinostat
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (...
T39968 TLR7/8 agonist 4 hydroxy-PEG10-acid
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by us...
T39970 TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor ...
T61601 TLR7/8 antagonist 2
TLR7/8 antagonist 2 (Compound 15) is a potent and orally active agonist of TLR7/8 with IC 50 s of 4.9 and 0.6 nM, respec...
T60894 TLR7/8 agonist 4
TLR7/8 agonist 4 (compound 41) is a potent agonist of TLR7/8 with anti-cancer activity [1].
T10899 CU-CPT17e TLR
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
T10315 AN-3485 Others
AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).
BC-1471
T8706
synonym:
Target:
TLR7/8 agonist 3
T13167
synonym:
Target:
TLR7/8/9-IN-1
T39669
synonym:
Target:
Afimetoran
T39654
synonym: BMS-986256
Target:
Pam3CSK4 TFA (112208-00-1 free base)
TP1067
synonym: Pam3Cys-Ser-(Lys)4 TFA , Pam3CSK4 TFA
Target:
4-Amino-1,3-dihydro-1-[(6-methyl-3-pyridinyl)methyl]-6-   [(tetrahydro-2H-pyran-4-yl)methoxy]-2H-imidazo[4,5-c]-pyridin-2-one
TNU0892
synonym:
Target:
Poseltinib
T4413
synonym:
Target:
NecroX-7
T9948
synonym: LC-280126 , LC28-0126 , LC28 0126
Target:
Immuno-Oncology Screening Library
T36421
synonym:
Target:
TLR8 agonist 2
T40039
synonym:
Target:
TLR7 agonist 3
T38614
synonym:
Target:
TLR8 agonist 2 hydrochloride
T40040
synonym:
Target:
TLR7/8 agonist 4 TFA
T39969
synonym:
Target:
Givinostat
T36629
synonym:
Target:
TLR7/8 agonist 4 hydroxy-PEG10-acid
T39968
synonym:
Target:
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
T39970
synonym:
Target:
TLR7/8 antagonist 2
T61601
synonym:
Target:
TLR7/8 agonist 4
T60894
synonym:
Target:
CU-CPT17e
T10899
synonym:
Target:
AN-3485
T10315
synonym:
Target:
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