T5539 |
GS-443902
|
1355149-45-9
|
98%
|
|
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
|
T37514 |
Hydroxy Dimetridazole
|
936-05-0
|
98%
|
|
Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections ...
|
T36061 |
N-Desmethyl Sildenafil
|
139755-82-1
|
98%
|
|
N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor.
|
T13564 |
AZ7550
|
1421373-99-0
|
98%
|
|
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
|
T20723 |
LGE-899
|
1221722-10-6
|
98%
|
|
LGE-899 is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.
|
T24047 |
Etilevodopa hydrochloride
|
39740-30-2
|
|
|
Etilevodopa HCl is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.
|
T12095 |
Monomethyl fumarate
|
2756-87-8
|
|
|
Monomethyl fumarate is a potent agonist of GPR109A .
|
T11641 |
N-Desmethyl imatinib
|
404844-02-6
|
|
|
N-Desmethyl imatinib is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.
|
T2687 |
Omeprazole sulfide
|
73590-85-9
|
100%
|
|
Omeprazole sulfide is a metabolite of Omeprazole, which is a proton pump inhibitor.
|
T4282 |
S-methyl-KE-298
|
143584-75-2
|
96.90%
|
|
S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from...
|
T4350 |
Palifosfamide
|
31645-39-3
|
97%
|
|
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...
|
TQ0045 |
2-Hydroxy atorvastatin calcium salt
|
265989-46-6
|
97.06%
|
|
2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt which is a potent HMG-CoA reductase inhibitor (IC50 = 8 nM).
|
T7440 |
P,p'-DDE
|
72-55-9
|
98%
|
|
4,4'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT
|
T5320 |
Tulipalin A
|
547-65-9
|
98%
|
|
Tulipalin A (2-Methylenebutyrolactone) which has some phytotoxicity is a natural compound extracted from Tulipa gesneriana.
|
T10157 |
Regorafénib N-oxyde (M2)
|
835621-11-9
|
98.03%
|
|
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2...
|
T10152 |
4-Methylamino antipyrine
|
519-98-2
|
98.20%
|
|
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methy...
|
T4000 |
(±)-Equol
|
94105-90-5
|
98.28%
|
|
Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (E...
|
T4710 |
3-Methoxytyramine hydrochloride
|
1477-68-5
|
98.42%
|
|
3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be foun...
|
T5158 |
N-Desmethylclozapine
|
6104-71-8
|
98.45%
|
|
N-Desmethylclozapine is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist a...
|
T0050 |
Ampyrone
|
83-07-8
|
98.57%
|
|
4-Aminoantipyrine is a reagent for glucose determination in the presence of peroxidase and phenol.
|