T10937L |
D-JNKI-1 acetate
|
AM-111 acetate , D-JNKI-1 acetate(1445179-97-4 Free base) |
JNK
|
|
D-JNKI-1 acetate is a highly potent and cell-permeable peptide inhibitor of JNK. |
TP1897L1 |
JIP-1 (153-163) acetate(438567-88-5 free base)
|
|
JNK
|
|
Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Bind... |
T39823L |
Apelin-12 acetate
|
|
Apelin receptor
,
p38 MAPK
,
JNK
|
|
Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 ... |
T2940 |
6-Hydroxyflavone
|
6-HF |
GABA Receptor
|
|
6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It... |
TL0004 |
FERULIC ACID METHYL ESTER
|
Methyl ferulate , Methyl 4'-hydroxy-3'-methoxycinnamate |
p38 MAPK
,
Autophagy
|
|
Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis)... |
T0860L |
Mefloquine
|
Ro215998 , Ro-215998 , Ro 215998 , WR 142490 , Lariam |
Others
|
|
Mefloquine is a phospholipid-interacting antimalarial drug effective against Plasmodium Falciparium with very few side e... |
T3060 |
Fasudil hydrochloride
|
AT-877 , HA-1077 hydrochloride , Fasudil HCl , Fasudil (HA-1077) HCl , HA-1077 |
Calcium Channel
,
ROCK
,
Serine/threonin kinase
,
HIV Protease
,
PKA
,
PKC
,
Autophagy
|
|
Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, r... |
T60534 |
JNK-IN-11
|
|
|
|
JNK-IN-11 (compound 1) is a potent inhibitor of JNK with the potential for Alzheimer's and Parkinson's disease research.... |
TP1353 |
L-JNKI-1
|
|
|
|
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity i... |
T38665 |
OVA-E1 peptide TFA
|
|
p38 MAPK
,
JNK
|
|
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes. |
T34262 |
RAPTA-C
|
|
|
|
RAPTA-C can induce apoptosis of EAC cells by mitochondrial and p53-JNK pathways. |
T26349 |
ZG-10
|
ZG10 , ZG 10 |
|
|
ZG-10 is a JNK1 inhibitor targeting JNK and p38 signaling. |
T36673 |
CC 401 dihydrochloride
|
|
|
|
High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of ac... |
T31550 |
DMA-CPPTL
|
DMACPPTL , DMA CPPTL |
|
|
DMA-CPPTL is a prodrug of CPPTL which induces apoptosis in a dose-dependent manner via the ROS/JNK pathway in acute myel... |
T8661 |
AS601245.2TFA (345987-15-7 free base)
|
AS601245.2TFA |
JNK
|
|
AS601245.2TFA is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respective... |
T39017 |
OVA-E1 peptide
|
|
|
|
OVA-E1 peptide, is an antagonist variant of SIINFEKL [OVA (257-264). OVA-E1 peptide, activates the p38 and JNK cascades ... |
TN4435 |
Licopyranocoumarin
|
|
P450
,
ROS
,
JNK
|
|
Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death an... |
TN4410 |
Lappaol C
|
|
P-gp
,
JNK
|
|
Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance throug... |
T61755 |
E6201
|
|
|
|
E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosph... |