Search Result

Search Results for "jnk"

Targets

Libraries

FDA-Approved Kinase Inhibitor Library Kinase Inhibitor Library

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Compounds

Cat No.	Product Name
T10937L	D-JNKI-1 acetate	AM-111 acetate , D-JNKI-1 acetate(1445179-97-4 Free base)	JNK
	D-JNKI-1 acetate is a highly potent and cell-permeable peptide inhibitor of JNK.		JNK
TP1897L1	JIP-1 (153-163) acetate(438567-88-5 free base)		JNK
	Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Bind...		JNK
T39823L	Apelin-12 acetate		Apelin receptor , p38 MAPK , JNK
	Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 ...		Apelin receptor , p38 MAPK , JNK
T2940	6-Hydroxyflavone	6-HF	GABA Receptor
	6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It...		GABA Receptor
TL0004	FERULIC ACID METHYL ESTER	Methyl ferulate , Methyl 4'-hydroxy-3'-methoxycinnamate	p38 MAPK , Autophagy
	Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis)...		p38 MAPK , Autophagy
T0860L	Mefloquine	Ro215998 , Ro-215998 , Ro 215998 , WR 142490 , Lariam	Others
	Mefloquine is a phospholipid-interacting antimalarial drug effective against Plasmodium Falciparium with very few side e...		Others
T3060	Fasudil hydrochloride	AT-877 , HA-1077 hydrochloride , Fasudil HCl , Fasudil (HA-1077) HCl , HA-1077	Calcium Channel , ROCK , Serine/threonin kinase , HIV Protease , PKA , PKC , Autophagy
	Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, r...
T60534	JNK-IN-11
	JNK-IN-11 (compound 1) is a potent inhibitor of JNK with the potential for Alzheimer's and Parkinson's disease research....
TP1353	L-JNKI-1
	L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity i...
T38665	OVA-E1 peptide TFA		p38 MAPK , JNK
	OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.		p38 MAPK , JNK
T34262	RAPTA-C
	RAPTA-C can induce apoptosis of EAC cells by mitochondrial and p53-JNK pathways.
T26349	ZG-10	ZG10 , ZG 10
	ZG-10 is a JNK1 inhibitor targeting JNK and p38 signaling.
T36673	CC 401 dihydrochloride
	High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of ac...
T31550	DMA-CPPTL	DMACPPTL , DMA CPPTL
	DMA-CPPTL is a prodrug of CPPTL which induces apoptosis in a dose-dependent manner via the ROS/JNK pathway in acute myel...
T8661	AS601245.2TFA (345987-15-7 free base)	AS601245.2TFA	JNK
	AS601245.2TFA is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respective...		JNK
T39017	OVA-E1 peptide
	OVA-E1 peptide, is an antagonist variant of SIINFEKL [OVA (257-264). OVA-E1 peptide, activates the p38 and JNK cascades ...
TN4435	Licopyranocoumarin		P450 , ROS , JNK
	Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death an...		P450 , ROS , JNK
TN4410	Lappaol C		P-gp , JNK
	Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance throug...		P-gp , JNK
T61755	E6201
	E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosph...