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Search Results for "raf"

Targets

Libraries

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Compounds

Cat No. Product Name
T6525 GW 5074 Raf1 Kinase Inhibitor I , GW5074 Apoptosis , Raf
GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MK...
T41003 KG5 FLT , Raf , c-Kit , PDGFR
KG5 is a dual allosteric inhibitor of PDGFRβ and B-Raf with a Kd of 520 nM and 300 nM for PDGFRβ and PDGFRα. KG5 inhibit...
T39738 ASP2453 Ras
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated...
T5172 AZ304 c-Fms , Raf , p38 MAPK , Autophagy
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (I...
T8823 Locostatin Raf
Locostatin is a potent and cell permeable inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and a...
T38511 AWL-II-38.3 Ephrin Receptor
AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular ac...
T9638 CCT241161 Raf
CCT241161 is an orally active pan- RAF inhibitor with IC 50 s of 3, 6, 10, 15 and 30 nM for LCK, CRAF, SRC, V600E-BRAF a...
T41284 Nalfurafine TRK-820 Opioid Receptor
Nalfurafine is an effective and selective agonist of G protein-biased κ-opioid receptor with high translational potentia...
T36642 RAS/RAS-RAF-IN-1
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYP...
T40284 B-Raf IN 2 Raf
B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be...
T60727 B-Raf IN 8
B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC 50 = 70.65 nM). B-Raf IN 8 shows antitumor activity which h...
T61935 B-Raf IN 9
B-Raf IN 9 (compound 8b) is an effective B-Raf inhibitor (IC50=24.79 nM). B-Raf IN 9 blocks cell cycle at G2/M phase and...
T22272 Lifirafenib BGB-283 , Beigene-283 EGFR , Raf
Lifirafenib is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM fo...
T30781 CCT3833 BAL3833 , BAL 3833 , CCT 3833 , CCT-3833 , BAL-3833
CCT3833, also known as BAL3833, is an orally available inhibitor of the serine/threonine-protein kinase family Raf, incl...
T18552 Pomalidomide-amido-C1-Br Others
Pomalidomide-amido-C1-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cer...
T12976 Sorafenib-d4 Bay 43-9006 (D4) , Sorafenib (D4) Others
Sorafenib D4 is the deuterium labeled Sorafenib. Sorafenib is an inhibitor of multikinase (Raf-1, B-Raf, and VEGFR-3 IC5...
T39117 PLX7922
PLX7922, a RAF inhibitor, can bind with BRAF V600E . PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK ...
T21602 PF-04880594
PF-04880594 is a potent and selective RAF inhibitor. PF-04880594 inhibits both wild-type and mutant BRAF and CRAF. PF-04...
T28510 REDX05358 REDX 05358 , REDX-05358
REDX05358 is a highly selective and potent pan RAF inhibitor with a potential therapeutic for BRAF and RAS mutant tumors...
T32086 HM95573 HM 95573 , HM-95573
HM95573 is an orally available inhibitor of members of the Raf family of serine/threonine protein kinases, with potentia...
GW 5074
T6525
synonym: Raf1 Kinase Inhibitor I , GW5074
Target:
KG5
T41003
synonym:
Target:
ASP2453
T39738
synonym:
Target:
AZ304
T5172
synonym:
Target:
Locostatin
T8823
synonym:
Target:
AWL-II-38.3
T38511
synonym:
Target:
CCT241161
T9638
synonym:
Target:
Nalfurafine
T41284
synonym: TRK-820
Target:
RAS/RAS-RAF-IN-1
T36642
synonym:
Target:
B-Raf IN 2
T40284
synonym:
Target:
B-Raf IN 8
T60727
synonym:
Target:
B-Raf IN 9
T61935
synonym:
Target:
Lifirafenib
T22272
synonym: BGB-283 , Beigene-283
Target:
CCT3833
T30781
synonym: BAL3833 , BAL 3833 , CCT 3833 , CCT-3833 , BAL-3833
Target:
Pomalidomide-amido-C1-Br
T18552
synonym:
Target:
Sorafenib-d4
T12976
synonym: Bay 43-9006 (D4) , Sorafenib (D4)
Target:
PLX7922
T39117
synonym:
Target:
PF-04880594
T21602
synonym:
Target:
REDX05358
T28510
synonym: REDX 05358 , REDX-05358
Target:
HM95573
T32086
synonym: HM 95573 , HM-95573
Target:
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