Search Result

Search Results for " raf "

Targets

194

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T2074	Raf inhibitor 1	B-Raf inhibitor 1	Raf
	B-Raf inhibitor 1 (B-Raf inhibitor 1) is a potent and selective B-Raf inhibitor.		Raf
T4167	Raf inhibitor 1 dihydrochloride	B-Raf inhibitor 1 dihydrochloride	Raf
	Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.		Raf
T4194	Raf inhibitor 2	CID-25014542,CID 25014542,CID25014542	Raf
	Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.		Raf
T1845	B-Raf IN 1		Raf
	B-Raf IN 1 is a B-Raf (IC50: 24 nM) and c-Raf (IC50: 25 nM) inhibitor.		Raf
T40284	B-Raf IN 2		Raf
	B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.		Raf
T19802	B-Raf IN 11		Raf
	B-Raf IN 11 is a novel selective inhibitor. The DFG-in conformation of the B-Raf kinase V600E mutant is superior to the DFG-out conformation in colorectal cancer.		Raf
T63644	Exarafenib	RAF/KIN_2787	Raf , p38 MAPK
	Exarafenib (RAF/KIN_2787) is a potent and orally available pan-RAF inhibitor.Exarafenib has antitumor activity and acts by inhibiting downstream MAPK pathway signaling.Exarafenib is used in cancer research.		Raf , p38 MAPK
T78183	B-Raf IN 15		Raf
	B-Raf IN 15 is a BRAF inhibitor that inhibits BRAFWT and BRAFV600E and can be used in the study of melanoma and cancer, and can be optimized for use as a more effective BRA F inhibitor.		Raf
T63333	Uplarafenib	B-Raf IN 10	Raf
	Uplarafenib (B-Raf IN 10) is a potent BRAF inhibitor with an IC50 in the range of 50-100 nM.B-Raf IN 10 has antitumor activity that may affect cell proliferation and differentiation did not, and can be used to study soli...		Raf
T79830	B-Raf IN 16		Raf
	B-Raf IN 16, a BRAF inhibitor, belongs to cyclic iminopyrimidine derivatives and can be used for cancer or tumour research.		Raf
T72070	B-Raf IN 14		Bradykinin Receptor
	B-Raf IN 14 is a BRAF inhibitor.		Bradykinin Receptor
T36642	RAS/RAS-RAF-IN-1
	RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1]. RAS/RAS-RAF-IN-1 (compound 89; for ...
T12685	RAF mutant-IN-1		Others
	RAF mutant-IN-1 is an inhibitor of RAF kinase(IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively).		Others
T67862	B-Raf IN 13		Raf
	B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.		Raf
T12556	PROTAC B-Raf degrader 1		Raf
	PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.		Raf
T3711	RAF709		Raf
	RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.		Raf
T63365	RAF-IN-1
	RAF-IN-1 is a potent inhibitor of b/cRAF, acting on cRAF (IC50: 3.8 nM), bRAFwt (IC50: 36 nM), bRAFV600E (IC50: 29.4 nM) and inhibiting A375 and H358 cell lines carrying the bRAFV600E mutation with a GI50 of 3.4 and 2.9 ...
T6296	RAF265	CHIR-265	Apoptosis , Raf , VEGFR , Autophagy
	RAF265 (CHIR-265) (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.		Apoptosis , Raf , VEGFR , Autophagy
T79813	Raf inhibitor 3		Raf
	Raf inhibitor 3 (Example 30), a potent inhibitor of both B-Raf and C-Raf, exhibits IC50 values below 15 nM. It is applicable in cancer research studies [1].		Raf
T64116	B-Raf IN 5
	B-Raf IN 5 is a potent inhibitor of the protein kinase B-Raf (IC50: 2.0 nM). B-Raf IN 5 resists rapid metabolism and does not bind to the secondary target PXR.
T60727	B-Raf IN 8
	B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC 50 = 70.65 nM). B-Raf IN 8 shows antitumor activity which has IC 50 values of 9.78, 13.78, 18.52 and 29.85 μM against hepatocellular carcinoma (HEPG-2), colon ...
T10599	BRAF inhibitor		Raf
	BRAF inhibitor is an inhibitor of B-Raf.		Raf
T61935	B-Raf IN 9
	B-Raf IN 9 (compound 8b) is an effective B-Raf inhibitor (IC50=24.79 nM). B-Raf IN 9 blocks cell cycle at G2/M phase and induces apoptosis. B-Raf IN 9 showed potent anti-tumor activity on human prostate cancer PC-3 cells...
T63855	B-Raf IN 6
	B-Raf IN 6 is a potent inhibitor (IC50: 1.7 nM) of the protein kinase B-Raf, which does not bind the secondary target PXR and is resistant to rapid metabolism.B-Raf IN 6 has shown research potential in cancer diseases.
T60933	B-Raf IN 7
	B-Raf IN 7 (compound 6a) is a potent inhibitor of B-Raf with an IC 50 of 110.23 nM. B-Raf IN 7 has antitumor activity against colon carcinoma cells(HCT-116), mammary gland cells(MCF-7), hepatocellular carcinoma cells(HEP...
T4133	CCT196969		Raf , Src
	CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.		Raf , Src
T63386	Pan-RAF kinase inhibitor 1
	Pan-RAF kinase inhibitor 1 is a potent inhibitor of the Pan-RAF kinase pair that inhibits RAF kinase and regulates MAPK signaling, thereby affecting the proliferation of RAS-mutated tumor cells. Pan-RAF kinase inhibitor ...
T72605	C-RAF kinase-IN-1
	C-RAF kinase-IN-1 is a potent inhibitor of C-RAF kinase with an IC 50 of 0.193 μM. C-RAF kinase-IN-1 is a quinoline derivative. C-RAF kinase-IN-1 has the potential for the research of cancer diseases .
T15794	LUT014		Raf
	LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.		Raf
TQ0048	BI-882370		Raf
	BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases.		Raf
T24437	MCP110	MCP-110,MCP 110	Raf , Ras
	MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.		Raf , Ras
T2295	SB-590885		Raf
	SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay). The selectivity of SB590885 for B-Raf is 11-fold greater over c-Raf, no acts to other human kinases.		Raf
T6487	Encorafenib	LGX818	Raf
	Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.		Raf
T6318	AZ 628		Apoptosis , Raf
	AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.		Apoptosis , Raf
T2473	PLX-4720	PLX4720	Raf
	PLX-4720 is a potent and selective inhibitor of B-Raf (V600E) (IC50: 13 nM), equally potent to c-Raf-1(Y340D and Y341D mutations).		Raf
T5172	AZ304		c-Fms , Raf , p38 MAPK , Autophagy
	AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).		c-Fms , Raf , p38 MAPK , Autophagy
T1886	TAK-632		Raf , FGFR , PDGFR , Aurora Kinase
	TAK-632 is a potent pan-Raf inhibitor.		Raf , FGFR , PDGFR , Aurora Kinase
T1953	L-779450	L 779450	Raf , Autophagy
	L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively.		Raf , Autophagy
T5634	Belvarafenib		Raf
	Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.		Raf
T1851	ZM 336372	Zinc00581684	Apoptosis , Raf
	ZM 336372 is a potent and selective c-Raf inhibitor.		Apoptosis , Raf
T41003	KG5		Raf , FLT , PDGFR , c-Kit
	KG5 is a dual allosteric inhibitor of PDGFRβ and B-Raf with a Kd of 520 nM and 300 nM for PDGFRβ and PDGFRα. KG5 inhibits FLT3, KIT, and c-Raf with anticancer and antiangiogenic activities.		Raf , FLT , PDGFR , c-Kit
T9693	TBAP-001		Raf
	TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.		Raf
T1903	Dabrafenib	GSK2118436A,GSK2118436	Raf
	Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma.		Raf
T4301	AD80		Raf , c-RET , Src , S6 Kinase
	AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.		Raf , c-RET , Src , S6 Kinase
T6949	PLX7904	PB04	Raf
	PLX7904 (PB04), also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutan...		Raf
T6320	GDC-0879	GDC 0879,AR-00341677,GDC0879	Raf
	GDC-0879 (AR-00341677) is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.		Raf
T11898	LXH254		Raf
	LXH254 is a potent C-Raf and B-Raf inhibitor.		Raf
T11224	Rineterkib	ERK-IN-1	ERK , Raf
	Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.		ERK , Raf
T6882	LY3009120	DP-4978	Raf , Autophagy
	LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.		Raf , Autophagy
T22272	Lifirafenib	BGB-283,Beigene-283	EGFR , Raf
	Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respective...		EGFR , Raf

Compounds

Raf inhibitor 1

T2074

Synonym: B-Raf inhibitor 1

Target: Raf

Raf inhibitor 1 dihydrochloride

T4167

Synonym: B-Raf inhibitor 1 dihydrochloride

Target: Raf

Raf inhibitor 2

T4194

Synonym: CID-25014542,CID 25014542,CID25014542

Synonym: RAF/KIN_2787

Target: Raf, p38 MAPK

Synonym: B-Raf IN 10

Target: Bradykinin Receptor

PROTAC B-Raf degrader 1

Target: Apoptosis, Raf, VEGFR, Autophagy

Pan-RAF kinase inhibitor 1

Synonym: MCP-110,MCP 110

Target: Apoptosis, Raf

Target: c-Fms, Raf, p38 MAPK, Autophagy

TAK-632

T1886

Synonym:

Target: Raf, FGFR, PDGFR, Aurora Kinase

L-779450

T1953

Synonym: L 779450

Target: Raf, Autophagy

Synonym: Zinc00581684

Target: Apoptosis, Raf

KG5

T41003

Synonym:

Target: Raf, FLT, PDGFR, c-Kit

Synonym: GSK2118436A,GSK2118436

Target: Raf, c-RET, Src, S6 Kinase

Synonym: GDC 0879,AR-00341677,GDC0879

Target: Raf, Autophagy

Lifirafenib

T22272

Synonym: BGB-283,Beigene-283

Target: EGFR, Raf

Cat No.	Product Name	Synonyms	Targets
T3S0309	D(+)-Raffinose pentahydrate	D-Raffinose pentahydrate,Raffinose	Others , Endogenous Metabolite
	D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) is a trisugar composed of fructose, galactose and glucose that occurs naturally in a variety of vegetables and grains. D(+)-Raffinose pentahydrate is a functional ol...		Others , Endogenous Metabolite
T8144	Raffinose	Melitose,Melitriose	Others , Endogenous Metabolite
	Raffinose (Melitriose) is an indigestible short-chain oligosaccharide, a trisaccharide composed of galactose, glucose and fructose, found in many plants. It can be hydrolyzed by α-galactosidase (α-GAL) to D-galactose and...		Others , Endogenous Metabolite
T5S1000	Sophoraflavanone G	Kushenol F,Vexibinol	Apoptosis
	Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways.		Apoptosis
TN5037	Sophoraflavanone H		Others
	Sophoraflavanone H is a natural product from Sophora moorcroftiana.		Others
TN5038	Sophoraflavanone I		Others
	Sophoraflavanone I is a natural product from Sophora moorcroftiana.		Others
TN3726	Cudraflavone B		IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy
	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may b...		IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy
TN4865	Putraflavone		Beta Amyloid , BACE
	Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.		Beta Amyloid , BACE
T5S2361	Epiberberine		ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE
	1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte diffe...		ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE
TN2114	Pseudoginsenoside Rh2		ERK , Raf , p53
	Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathway. (20Z) -Pseudoginsenoside Rh2 and (20E)-Pseudoginsenosid...		ERK , Raf , p53
T16011	Manumycin A		Prostaglandin Receptor
	Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling. Manumycin A acts as a ...		Prostaglandin Receptor
T72803	Norartocarpetin
	Norartocarpetin is a potent tyrosinase inhibitor exhibiting significant antibrowning properties useful for food system research, with an IC50 of 0.47 μM. Furthermore, it demonstrates substantial anticancer activity speci...
TN4166	Griffipavixanthone		ERK , Raf , ROS , MEK , Caspase
	Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS productio...		ERK , Raf , ROS , MEK , Caspase
T35577	Phosphatidylserines (bovine)
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...
T14055	5Z-7-Oxozeaenol	FR148083,L783279,LL-Z 1640-2	VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
	5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...		VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src

Natural Products

D(+)-Raffinose pentahydrate

T3S0309

Synonym: D-Raffinose pentahydrate,Raffinose

Target: Others, Endogenous Metabolite

Raffinose

T8144

Synonym: Melitose,Melitriose

Target: Others, Endogenous Metabolite

Sophoraflavanone G

T5S1000

Synonym: Kushenol F,Vexibinol

Target: IκB/IKK, MAO, ROS, Akt, COX, PI3K, Nrf2, Autophagy

Putraflavone

TN4865

Synonym:

Target: Beta Amyloid, BACE

Epiberberine

T5S2361

Synonym:

Target: ERK, Beta-Secretase, MEK, BACE, AMPK, AChR, AChE

Pseudoginsenoside Rh2

TN2114

Synonym:

Target: ERK, Raf, p53

Manumycin A

T16011

Synonym:

Target: Prostaglandin Receptor

Target: ERK, Raf, ROS, MEK, Caspase

Phosphatidylserines (bovine)

Synonym: FR148083,L783279,LL-Z 1640-2

Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-05095	RAF1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds direct...
TMPY-03297	BMP-2 Protein, Danio rerio (zebrafish), Recombinant	Danio rerio (zebrafish)	E. coli
	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-03080	VEGF165 Protein, Danio rerio (zebrafish), Recombinant	Danio rerio (zebrafish)	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPH-03743	IL-1 beta Protein, Zebrafish, Recombinant (His)	Danio rerio (Zebrafish)	E. coli

TMPH-02209	TRAF5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation o...
TMPH-03744	IL-1 beta Protein, Zebrafish, Recombinant (His & Myc)	Danio rerio (Zebrafish)	E. coli

TMPH-02210	TRAF6 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/u...
TMPY-03633	EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His)	Danio rerio (zebrafish)	HEK293
	Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Ep...
TMPH-01995	RAF1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	RAF1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02207	TRAF3 Protein, Human, Recombinant (His)	Human	E. coli
	Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon....
TMPY-03632	EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc)	Danio rerio (zebrafish)	HEK293
	Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Ep...
TMPH-02208	TRAF3 Protein, Human, Recombinant	Human	E. coli
	Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon....
TMPH-03745	TNF-alpha Protein, Zebrafish, Recombinant (His)	Danio rerio (Zebrafish)	E. coli

TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His)	Human	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-00146	RKIP/PEBP1 Protein, Human, Recombinant	Human	E. coli
	Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that mon...
TMPY-01715	CDC37 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-03534	CDC37 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-03558	CDC37 Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-04411	YES1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /...
TMPY-01566	Prolactin Receptor Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-02984	Prolactin Receptor Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-02434	Prolactin Receptor Protein, Rat, Recombinant (His)	Rat	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-06345	KRAS Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-06138	KRAS Protein, Human, Recombinant (61Q, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...

RAF1 Protein, Human, Recombinant (His & GST)

TMPY-05095

Species: Human

Expression System: Baculovirus-Insect Cells

BMP-2 Protein, Danio rerio (zebrafish), Recombinant

TMPY-03297

Species: Danio rerio (zebrafish)

Expression System: E. coli

VEGF165 Protein, Danio rerio (zebrafish), Recombinant

TMPY-03080

Species: Danio rerio (zebrafish)

Expression System: Baculovirus-Insect Cells

IL-1 beta Protein, Zebrafish, Recombinant (His)

TMPH-03743

Species: Danio rerio (Zebrafish)

Expression System: E. coli

TRAF5 Protein, Human, Recombinant (His & SUMO)

TMPH-02209

Species: Human

Expression System: E. coli

IL-1 beta Protein, Zebrafish, Recombinant (His & Myc)

TMPH-03744

Species: Danio rerio (Zebrafish)

Expression System: E. coli

TRAF6 Protein, Human, Recombinant (His & SUMO)

TMPH-02210

Species: Human

Expression System: E. coli

EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His)

TMPY-03633

Species: Danio rerio (zebrafish)

Expression System: HEK293

RAF1 Protein, Human, Recombinant (His & SUMO)

TMPH-01995

Species: Human

Expression System: E. coli

TRAF3 Protein, Human, Recombinant (His)

TMPH-02207

Species: Human

Expression System: E. coli

EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc)

TMPY-03632

Species: Danio rerio (zebrafish)

Expression System: HEK293

TRAF3 Protein, Human, Recombinant

TMPH-02208

Species: Human

Expression System: E. coli

TNF-alpha Protein, Zebrafish, Recombinant (His)

TMPH-03745

Species: Danio rerio (Zebrafish)

Expression System: E. coli

Prolactin Receptor Protein, Human, Recombinant (His)

TMPY-01053

Species: Human

Expression System: HEK293

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

TMPY-04113

Species: Human

Expression System: E. coli

KRAS Protein,Human, Recombinant (Q61H, His)

TMPY-01888

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (G12D, His)

TMPY-06056

Species: Human

Expression System: E. coli

KRAS Protein,Human,Recombinant(G12C & Q61H, His)

TMPY-04116

Species: Human

Expression System: E. coli

RKIP/PEBP1 Protein, Human, Recombinant

TMPY-00146

Species: Human

Expression System: E. coli

CDC37 Protein, Human, Recombinant (GST)

TMPY-01715

Species: Human

Expression System: Baculovirus-Insect Cells

CDC37 Protein, Mouse, Recombinant (His & GST)

TMPY-03534

Species: Mouse

Expression System: Baculovirus-Insect Cells

CDC37 Protein, Mouse, Recombinant

TMPY-03558

Species: Mouse

Expression System: Baculovirus-Insect Cells

YES1 Protein, Human, Recombinant (His & GST)

TMPY-04411

Species: Human

Expression System: Baculovirus-Insect Cells

Prolactin Receptor Protein, Mouse, Recombinant (His & hFc)

TMPY-01566

Species: Mouse

Expression System: HEK293

Prolactin Receptor Protein, Mouse, Recombinant (His)

TMPY-02984

Species: Mouse

Expression System: HEK293

Prolactin Receptor Protein, Rat, Recombinant (His)

TMPY-02434

Species: Rat

Expression System: HEK293

KRAS Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06345

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (61Q, His)

TMPY-06138

Species: Human

Expression System: E. coli

Cat No.	Product Name
L2192	Anti-Pancreatic Cancer Compound Library	2267 compounds
	A unique collection of 2267 pancreatic cancer related compounds can be used in HTS and HCS;
L1610	FDA-Approved Kinase Inhibitor Library	266 compounds
	A unique collection of 266 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L1600	Kinase Inhibitor Library	2720 compounds
	A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;

Libraries

Anti-Pancreatic Cancer Compound Library

L2192

Compounds: 2267

FDA-Approved Kinase Inhibitor Library

L1610

Compounds: 266

Kinase Inhibitor Library

L1600

Compounds: 2720