ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.

Simmitecan hydrochloride is a camptothecin derivative, a topoisomerase I inhibitor with anticancer activity, which can be used to study is solid tumors.

Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetrabenazine Metabolite is often used to study chorea associated with Huntington's disease and other hyperactivity disorders.

Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an apoptosis inducer.

Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster and more consistent inhibition on ADP-receptors. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).

Ferumoxytol (Magnetic Black) is a non-gadolinium based contrast agent for use in magnetic resonance imaging applications.

Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity for cancer research.

(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.

Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties.

Emitefur (BOF-A 2) is an orally active and potent 5-fluorouracil derivative with anticancer and antitumor activity.Emitefur is used in advanced gastric cancer, breast cancer and metabolism-related diseases.

Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.

Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer.

Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR transcriptional activity with an IC50 value of 7.4 μM.Ralanites have anticancer activity and can be used to study desmoplasia-resistant prostate cancer (CRPC).

Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.

Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is a first-of-its-kind, orally active androgen receptor N-terminal structural domain (AR-NTD) inhibitor with anticancer activity and can be used to study prostate and breast cancer.

Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.

Triptonoditerpenic acid is an aromatic pimarane diterpenoid that can be isolated from Tripterygium wilfordii. It exhibits cytotoxicity against HepG2, Hep3B, and Bcap37 cell lines, with IC50 values of 42.53 μM, 29.74 μM, and 37.63 μM, respectively.

Nicardipine pyridine metabolite II is a biaoctive chemical.

5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, exhibits remarkable safety and antisense activity [1] [2].

Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases including spinal muscular atrophy.

Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.

DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.

Chimmitecan ((S)-9-Allyl-10-hydroxycamptothecin) is a potent inhibitor of topoisomerase I and displays outstanding activity in vitro and in vivo.

Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)

AR-13324 M1 metabolite is a hydrolysis metabolite of AR-13324 mesylate.

Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease.

Ditekiren is a renin inhibitor with orally active.

Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.

DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.

BRITE-338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA in bacteria with IC50 value of 4.7 μM for the bacterial infections treatment.

Disitertide (P144) is an inhibitor of TGF-β1.

Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.

Abemaciclib metabolite M18 (LSN3106729) is a potent cyclin-dependent kinase (CDK) inhibitor with antitumor properties. It has been incorporated alongside a cereblon (CRBN) ligand to develop a proteolysis-targeting chimera (PROTAC) that selectively degrades CDK4/6 [1] [2].

5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits attributes akin to LNA, including hybridization and mismatch discrimination capabilities. Additionally, it demonstrates resistance to exonuclease digestion [1].

DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.

Menadione bisulfite sodium (Vitamin K3 sodium bisulfite) is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement.

Efmitermant alfa (ACE-083), a follistatin-based fusion protein with localized action, functions as a muscle-promoting agent and is utilized in the study of muscle disorders [1] [2].

Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has trypanocidal activity, the minimum lethal concentration against epimastigotes

GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral bioavailability.

6 -O-Acetylisovitexin is a natural product for research related to life sciences. The catalog number is TN5450 and the CAS number is 1223097-20-8.

Aramite is an insecticide that may have carcinogenic effects on mammals.

5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog belonging to the class of modified antisense oligonucleotide [1].

DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.

Itepekimab (REGN-3500) is a potent monoclonal antibody against IL-33.Itepekimab reduces airway inflammation and associated tissue damage in in vivo experiments and can be used to study asthma.

N-desmethyl Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.

Sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC) targeting Trop-2, facilitates the delivery of SN-38. It demonstrates anticancer activity [1].

Labetuzumab govitecan is an anti-CEACAM5/SN-38 antibody-drug conjugate for therapy of refractory or relapsing metastatic colorectal cancer.

Vitexin2''-O-p-trans-coumarate, a flavonoid derived from the ethyl acetate-soluble fraction of the ethanol extract of Trigonella foenum-graecum seeds, notably enhances the proliferation of 2BS cells in the presence of H2O2 [1].