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Results for "rho" in TargetMol Product Catalog
  • Inhibitor Products
    143
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Rho-Kinase-IN-1
T127211035094-83-7In house
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation diseases.
  • $135
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DCP-Rho1
T365021001575-98-9
DCP-Rho1 is a fluorescent probe for the detection of sulfenic acid-containing proteins.1,2 It displays excitation/emission maxima of 560/581 nm, respectively, and has been used to visualize protein oxidation sites in situ. |1. Klomsiri, C., Rogers, L.C., Soito, L., et al. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Rad. Biol. Med. 71, 49-60 (2014).|2. Holmila, R.J., Vance, S.A., Chen, X., et al. Mitochondria-targeted probes for imaging protein sulfenylation. Sci. Rep. 8(1), 6635 (2018).
  • $243
35 days
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Rho-Kinase-IN-2
T614972573071-18-6
Rho-Kinase-IN-2 (Compound 23) is an orally active and selective inhibitor of Rho Kinase (ROCK), which can penetrate the central nervous system (CNS). It exhibits a high affinity for ROCK2 with an inhibition constant (IC50) of 3 nM. This compound is of potential interest for further investigations in the field of Huntington's disease research [1].
  • $916
6-8 weeks
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Conopeptide rho-TIA
T80175381725-58-2
Conopeptide rho-TIA, a peptide from Conus tulipa venom, acts as a selective, noncompetitive inhibitor at the human α1B-Adrenergic Receptor and as a competitive inhibitor at the α1A and α1D-Adrenergic Receptors. Binding to these subtypes, conopeptide rho-TIA may inform the creation of new α1-Adrenergic Receptor subtype-selective drugs [1].
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Hydroxyfasudil Hydrochloride
T4276155558-32-0
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).
  • $34
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Rhosin hydrochloride
T167451281870-42-5
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin h
  • $162
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Rhodamine B
T797581-88-9
Rhodamine B (Brilliant Pink B) is used as a tracer dye in water to determine the rate and direction of flow and transport.
  • $33
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Rhodblock 6
T26078886625-06-5
Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity.
  • $106
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Rhoduline Acid
T1998187-03-6In house
Rhoduline Acid (Di-J acid) is an intermediate in the synthesis of diazo dyes and tetranitazole dyes.
  • $195
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Rhodopsin Epitope Tag acetate
TP1865L
Rhodopsin Epitope Tag acetate is a 9-amino acid peptide representing C terminus of bovine rhodopsin widely used as an epitope tag. A number of anti-rhodopsin antibodies can recognize this epitope.
  • $82
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Rhododendrol
T19924501-96-2
Rhododendrol (Frambinol) is a melanin synthesis and acts by preventing high-fat diet-induced elevation in body weight and increasing lipolysis in white adipocytes in male mice. Rhododendrol can be used as the lightening/whitening cosmetics inhibitor.
  • $95
In Stock
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GSK429286A
T2633864082-47-3
GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).
  • $35
In Stock
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Y-27632 dihydrochloride
T1725129830-38-2
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
  • $39
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Netarsudil Dihydrochloride
T103581253952-02-1
Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.
  • $96
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Y-27632
T1870146986-50-7
Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
  • $39
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Y16
T3553429653-73-6
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.
  • $30
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Thiazovivin
T21551226056-71-8
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
  • $30
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Rhodiocyanoside A
TN2155168433-86-1
Rhodiocyanoside A has antiallergic activity, it exhibits inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE and inhibits the PCA reaction in rats.
  • $670
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Myrrhone
TN1963183551-83-9
Myrrhone is a natural product
  • $423
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Rhodonocardin B
T126400110429-59-9
Rhodonocardin B is a useful organic compound for research related to life sciences. The catalog number is T126400 and the CAS number is 110429-59-9.
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Rhodiolin
T1386886831-53-0
Rhodiolin is a natural product(flavonoid) isolated from Rhodiola fastigita.
  • $237
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Rhoeadine
TN49102718-25-4
Rhoeadine is a natural product for research related to life sciences. The catalog number is TN4910 and the CAS number is 2718-25-4.
  • $520
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9-Methoxymyrrhone
TN13501809980-22-0
9-Methymyrrhone is a natural product
  • $550
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Rhodomyrtone
TN6133468757-69-9
Rhodomyrtone is a natural product for research related to life sciences. The catalog number is TN6133 and the CAS number is 468757-69-9.
  • $1,750
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Rhombifoline
TN2156529-78-2
Rhombifoline is a family of alkaloids isolated from the leaf stems of Anagyrus foetida and Genista tenera.
  • $48
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Phalloidin-Tetramethylrhodamine Conjugate
T36853
Phalloidin-retramethylrhodamine conjugate is an orange fluorescent probe (ex/em = 546/575 nm) that selectively binds to F-actin. It can be used to localize actin filaments in living or fixed cells, as well as for visualizing individual actin filaments in vitro.
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Lissamine rhodamine B sulfonyl chloride
T2077362796-29-6
Lissamine rhodamine B sulfonyl chloride is a fluorescent label used for forming stable conjugates with protein.
  • $2,500
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Dracorhodin
T40741643-56-1
Dracorhodin, the primary constituent found in the sanguis draconis extract, is a flavylium compound classified within the anthocyanin family. Notably, dracorhodin possesses the ability to elicit vasodilation.
  • $1,520
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Fasudil
T1606103745-39-7
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
  • $33
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IMM-01
T25529218795-74-5
IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics[1].
  • $81
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H-1152 dihydrochloride
T35328871543-07-6In house
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
  • $58
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Chroman 1
T149601273579-40-0In house
Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM).
  • $70
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LX7101
T157981192189-69-7In house
LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
  • $56
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CCG-257081
T307781922098-90-5In house
CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MRTF/SRF pathway.CCG-257081 has shown efficacy in preventing bleomycin-induced fibrosis in several mouse models. CCG-257081 can be used in cancer prevention and fibrosis research.
  • $129
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Rhosin
T167461173671-63-0
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin causes cell apoptosis.
  • $1,520
6-8 weeks
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Rhodblock 3
T26077879564-86-0
Rhodblock 3 is a potent small molecule Rho pathway inhibitor.
  • $1,520
6-8 weeks
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Rhodomyrtosone I
TN61731402725-98-7
Rhodomyrtosone I is a natural product for research related to life sciences. The catalog number is TN6173 and the CAS number is 1402725-98-7.
  • $820
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Rhoifolin
T275517306-46-6
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
  • $120
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TargetMol | Citations Cited
Rhododendrol, (+/-)-
T3432169617-84-1
Rhododendrol, (+/-)-, is an aromatic compound that may be useful in the treatment of hepatic diseases. However, this product is a known pro-oxidant which can be toxic to melanocytes.
  • $970
7-10 days
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Rhodamine-6G N-Phenyl-thiosemicarbazide
T64845
1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylthiourea is a useful organic compound for research related to life sciences and the catalog number is T64845.
    7-10 days
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    Pyrrhocoricin
    T80250224569-84-0
    Pyrrhocoricin is a bioactive peptide exhibiting antimicrobial activity against Gram-negative bacteria.
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    Apiosylrhododendrin
    T125826146609-83-8
    Apiosylrhododendrin is a useful organic compound for research related to life sciences. The catalog number is T125826 and the CAS number is 146609-83-8.
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    Isorhodoptilometrin
    T12382397995-25-0
    Isorhodoptilometrin is a useful organic compound for research related to life sciences. The catalog number is T123823 and the CAS number is 97995-25-0.
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    Rhodexin A
    T34320545-49-3
    Rhodexin A is a cardetonic agent of the plant Rhodea japonica.
    • $1,520
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    Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II)
    T67239909389-99-7
    Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) is a useful organic compound for research related to life sciences. The catalog number is T67239 and the CAS number is 909389-99-7.
      7-10 days
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      24-Norhopa-4(23),22(29)-diene-3β,6β-diol
      TN2823194613-74-6
      24-Norhopa-4(23),22(29)-diene-3β,6β-diol is a natural product for research related to life sciences. The catalog number is TN2823 and the CAS number is 194613-74-6.
      • $710
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      Isorhoifolin
      TN1797552-57-8
      Isorhoifolin and vicenin II are main compounds of ethyl acetate fraction (EAcF) obtained from Erythrina velutina leaves, EAcF increases the cardiac contractile force by increasing the l-type calcium current and activating the adrenergic receptor pathway.
        7-10 days
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        Tetramethylrhodamine-dUTP
        T75385
        Tetramethylrhodamine-dUTP (TAMRA-dUTP) is used for end-labeling of DNA [1] .
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        Rhodionin
        TN101185571-15-9
        N-Acetyl-L-aspartic acid is a derivative of aspartic acid, synthesized in neurons from the amino acid aspartic acid and acetyl coenzyme A. N-Acetyl-L-aspartic acid has antioxidant activity.
        • $64
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        Tetrahydrorhombifoline
        T800043382-84-1
        Tetrahydrorhombifoline, a quinolizidine alkaloid found in the aerial parts of Genista vuralii A. Duran & H. Dural (Fabaceae), exhibits antibacterial and antifungal activities as evidenced by the extract from G. vuralii [1].
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