TN3486 |
Bakkenolide IIIa
|
915289-60-0
|
98%
|
|
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB...
|
TN3806 |
Dehydroglyasperin C
|
199331-35-6
|
98%
|
|
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
|
TN1889 |
Lupalbigenin
|
76754-24-0
|
98%
|
|
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
|
TN1793 |
Isorhamnetin 3-O-galactoside
|
6743-92-6
|
98%
|
|
Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a candidate therapeutic...
|
T4082 |
Astragaloside
|
T4082
|
98%
|
|
Astragaloside, one of the main active ingredients in Astragalus membranaceus.
|
TN3541 |
Broussonin E
|
90902-21-9
|
98%
|
|
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathwa...
|
TN4469 |
(+)-Lyoniresinol
|
14464-90-5
|
98%
|
|
Lyoniresinol has antioxidant effect, it shows robust anti-melanogenic activity, decreases tyrosinase activity and melanin biosynthesis in B16F10 cells by activat...
|
TN4374 |
Kaerophyllin
|
75590-33-9
|
98%
|
|
Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting H...
|
T12410 |
PERK-IN-3
|
1337532-08-7
|
98%
|
|
PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).
|
TN5100 |
Taspine
|
602-07-3
|
98%
|
|
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
|
TN1996 |
Nothofagin
|
11023-94-2
|
98%
|
|
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhes...
|
TN1211 |
2-Hydroxy-3-methylanthraquinone
|
17241-40-6
|
98%
|
|
2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activ...
|
TN4683 |
Nyasol
|
96895-25-9
|
98%
|
|
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory ...
|
TN3614 |
Cearoin
|
52811-37-7
|
98%
|
|
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...
|
TN3525 |
Boehmenan
|
57296-22-7
|
98%
|
|
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ...
|
T10809L |
CHPG hydrochloride
|
T10809L
|
98%
|
|
CHPG hydrochloride is a selective agonist of mGluR5.
|
TN3003 |
4-(3,4-Dimethoxyphenyl)-3-buten-1-ol
|
69768-97-4
|
98%
|
|
(E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol may promote melanin synthesis via USF1 dependent fashion and could be used as a clinical therapeutic agent against hypop...
|
T10299 |
AMG PERK 44
|
1883548-84-2
|
98%
|
|
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) and induces autophagy. It has 1000-fold and 160-fold selectivity over GCN2 (IC50: 7300 ...
|
TL0014 |
Pinusolide
|
31685-80-0
|
98%
|
|
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a...
|
T16390 |
Omtriptolide
|
195883-06-8
|
98%
|
|
Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.
|