T4082 |
Astragaloside
|
17429-69-5
|
90%
|
|
Astragaloside, one of the main active ingredients in Astragalus membranaceus.
|
T11225 |
ERK-IN-2
|
2743576-56-7
|
98%
|
|
ERK-IN-2 is a ERK2 inhibitor with an IC 50 value of 1.8 nM. ERK-IN-2 might cause off-target toxicity and/or off-target activity at dose >10 μM [1].
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
TN4877 |
Quercetin 3,4'-dimethyl ether
|
33429-83-3
|
98%
|
|
Quercetin 3,4'-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM), it also shows anti-inflammatory activity. Quercetin 3,4'-dimethyl ...
|
TN1653 |
Fustin
|
20725-03-5
|
98%
|
|
Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.
|
TN2114 |
Pseudoginsenoside Rh2
|
1370264-16-6
|
98%
|
|
Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathw...
|
TN1953 |
Morusinol
|
62949-93-3
|
98%
|
|
Morusinol is a flavonoid extracted from the root bark of Morus alba. Morusinol has antiplatelet and anticancer activities, inhibits arterial thrombosis in vivo, ...
|
TN3525 |
Boehmenan
|
57296-22-7
|
98%
|
|
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ...
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
T16390 |
Omtriptolide
|
195883-06-8
|
98%
|
|
Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
TN1889 |
Lupalbigenin
|
76754-24-0
|
98%
|
|
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
|
TN4774 |
Physalin A
|
23027-91-0
|
98%
|
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
|
TN1062 |
Peonidin chloride
|
134-01-0
|
98%
|
|
Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer cells in vitro, notably metastatic human breast c...
|
TN3139 |
5α-Hydroxycostic acid
|
132185-83-2
|
98%
|
|
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.
|
TN1751 |
Hydroxycitric acid
|
6205-14-7
|
98%
|
|
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to ac...
|
TN1775 |
Isocryptotanshinone
|
22550-15-8
|
98%
|
|
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative r...
|
T15377 |
Ravoxertinib hydrochloride
|
2070009-58-2
|
98%
|
|
Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).
|
TMA1743 |
Ergosterol peroxide
|
2061-64-5
|
98%
|
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
|
T10299 |
AMG PERK 44
|
1883548-84-2
|
98%
|
|
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) and induces autophagy. It has 1000-fold and 160-fold selectivity over GCN2 (IC50: 7300 ...
|