TN1086 |
Dehydrotrametenolic acid
|
6879-05-6
|
|
|
Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in ...
|
TN3404 |
Altholactone
|
65408-91-5
|
98%
|
|
Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of ...
|
TN2257 |
Tanshinone IIB
|
17397-93-2
|
98%
|
|
Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a...
|
TN4932 |
Sageone
|
142546-15-4
|
98%
|
|
Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gast...
|
T79497 |
M826
|
|
98%
|
|
M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity in vitro...
|
T79498 |
M867
|
680999-39-7
|
98%
|
|
M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].
|
T79747 |
M190S
|
2578300-07-7
|
98%
|
|
M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo. It shows promise...
|
T79992 |
Sarglaroids F
|
|
98%
|
|
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+ efflu...
|
T80093 |
IETD-CHO TFA
|
|
98%
|
|
IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1].
|
T80109 |
Z-VEID-AFC
|
219138-06-4
|
98%
|
|
Z-VEID-AFC is a caspase-6 fluorescent substrate [1].
|
T80110 |
Ac-VRPR-AMC
|
919515-51-8
|
98%
|
|
Ac-VRPR-AMC is a fluorogenic substrate for metacaspase activity assays, facilitating the detection and measurement of metacaspase activity [1].
|
T80201 |
Tripeptide-32
|
1185583-20-3
|
98%
|
|
Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].
|
T80467 |
Boc-AEVD-CHO
|
220094-15-5
|
98%
|
|
Boc-AEVD-CHO, a selective Caspase 8 inhibitor, facilitates apoptosis research and the investigation of immune and inflammatory diseases [1] [2].
|
T80531 |
Ac-AAVALLPAVLLALLAP-DEVD-CHO
|
201608-15-3
|
98%
|
|
Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) serves as a potent and reversible inhibitor of caspase-3 [1].
|
T80532 |
Ac-AAVALLPAVLLALLAP-YVAD-CHO
|
201608-12-0
|
98%
|
|
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1].
|
T80536 |
Ac-AAVALLPAVLLALLAP-LEVD-CHO
|
886462-82-4
|
98%
|
|
Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable inhibitor of caspase-4 that exhibits antitumor activity [1].
|
T80537 |
Ac-AAVALLPAVLLALLAP-LEHD-CHO
|
623948-42-5
|
98%
|
|
Ac-AAVALLPAVLLALLAP-LEHD-CHO is a caspase inhibitor targeting caspases 4, 5, and 9, demonstrating protective effects in MCF-7 cells treated with Neocarzinostatin...
|
T80545 |
Ac-VEID-AFC
|
|
98%
|
|
Ac-VEID-AFC is a fluorogenic substrate for caspase-6, utilized in caspase-6 activity assays [1].
|
T80624 |
Ac-VAD-CHO
|
147837-52-3
|
98%
|
|
Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release of cytochrome...
|
T80659 |
Z-YVAD-CMK
|
402474-85-5
|
98%
|
|
Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].
|