T0282 |
Q-VD-OPH |
Q-VD-OPha is a pan-caspase inhibitor with potent antiapoptotic properties. |
T1772 |
Apoptosis Activator 2 |
Apoptosis Activator 2 is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation . |
T2503 |
PAC1 |
PAC-1 has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others. |
T3519 |
Polyphyllin B |
Polyphyllin B is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal system...
|
T3600 |
Licochalcone A |
Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects. |
T3907 |
Senegenin |
Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity. |
T3914 |
Saikosaponin C |
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation. |
T6005 |
Z-DEVD-FMK |
Z-DEVD-FMK is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10. |
T6013 |
Z-VAD(OMe)-FMKHOT |
Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor. It inhibits cleavage of PARP, preventing apoptosis when used at 10-50 µM. |
T6090 |
Belnacasan |
VX-765 is an orally active IL-converting enzyme/caspase-1 inhibitor. |
T6191 |
Tasisulam |
Tasisulam is an apoptosis inducer and an antitumor agent via the intrinsic pathway. |
T6826 |
Emricasan |
Emricasan is an effective and irreversible pan-caspase inhibitor. |
T7016 |
VR23 |
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for ...
|
T7019 |
Z-IETD-FMK |
Z-IETD-FMK is a selective caspase 8 inhibitor, which has cell permeable. |
T7020 |
Z-VAD(OH)-FMK |
Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor. |
T3S0335 |
Soyasaponin Bb |
1. Soyasaponin Bb can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kap...
|
T3S1227 |
Aristololactam I |
1. Aristololactam I has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may ...
|
T4S0498 |
Glaucocalyxin A |
1. Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases...
|
T4S1335 |
Daphnoretin |
1. Daphnoretin has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcom...
|
T5S2283 |
Sesamolin |
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 a...
|
T2A2481 |
Taurochenodeoxycholic Acid |
Taurochenodeoxycholic acid is one of the main bioactive substances of animals' bile acid. |
T5S1632 |
8-O-Acetylshanzhiside methyl ester |
8-O-Acetylshanzhiside methylester has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might b...
|
T5574 |
Guggulsterone E&Z |
Guggulsterone E&Z is a 3-hydroxy steroid. It has a role as an androgen. |
T5558 |
Chelidonic acid |
Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also s...
|
T4S2012 |
Dihydro Sanguinarine |
Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa,and has antifungal and anticancer activity. |
T5S2083 |
Puerarin 6''-O-Xyloside |
Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are relat...
|
TQ0146 |
Ac-DEVD-CHO |
Ac-DEVD-CHO is a selective Caspase-3 inhibitor (Ki: 230 pM). |
T2122 |
Ixazomib |
MLN2238, a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (I...
|
TJA2398 |
Taurohyodeoxycholic acid sodium salt |
Taurohyodeoxycholic acid sodium salt, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat. |
T8296 |
4',5,7-Trimethoxyflavone |
5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand. |
TN1466 |
Canthin-6-one |
Canthin-6-one has antimicrobial, cytotoxic, antiproliferative and proapoptotic effects, possibly by interfering with the G2/M transition; it also has antiinflam...
|
TN1538 |
Curzerenone |
Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52). |
TN1601 |
Effusol |
Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues...
|
TN1814 |
Juncusol |
Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; it can induce caspase-3-mediated cytotoxicity in HT22 ce...
|
TN2175 |
Salvianolic acid F |
The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentrati...
|
TN2191 |
Scutebarbatine A |
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of casp...
|
TN2217 |
Sophoflavescenol |
Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , th...
|
TN1039 |
Tamarixetin |
Tamarixetin has vasodilator effects in rat isolated vessels. Tamarixetin has cytotoxic against leukemia cells and in particular P-glycoprotein- overexpressing K...
|
TN1087 |
Deoxypodophyllotoxin |
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflamma...
|
TN1139 |
Dehydrocavidine |
Dehydrocorydaline has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as we...
|
TN1153 |
Polyporenic acid C |
Polyporenic acid C shows inhibitory activity against human collagenase. |
TN1393 |
(-)-Anonaine |
(-)-Anonaine has some anticancer activity, it induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells, it induces DN...
|
TN1532 |
Crenulatin |
Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, inhibitive effect in 25 mg/L and stimulative effect in 100 mg/L...
|
TN1677 |
Gartanin |
Gartanin is an androgen receptor degradation enhancer, it is also a potential neuroprotective agent against glutamate-induced oxidative injury partially through...
|
TN1807 |
Isoverticine |
Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity. |
TN1837 |
Kuguaglycoside C |
Kuguaglycoside C induces caspase-independent cell death, and is involved, at least in part, in the mechanism underlying cell necroptosis. |
TN1875 |
Liriodenine |
Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can...
|
TN2002 |
Obovatol |
Obovatol has antioxidant, neuroprotective, antiinflammatory, antithrombotic and antitumour effects, it is a potent NF-κB inhibitors for Alzheimer's disease tre...
|
TN2019 |
Orobol |
Orobol is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover, it has sensitization effect, it can produce produced cisplatin (DD...
|
TN2034 |
Paeoniflorigenone |
Paeoniflorigenone is a depolarizing neuromuscular blocking agent, being similar to succinylcholine. |
TN2040 |
Panaxynol |
Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation. |
TN2063 |
Physalin B |
Physalin B shows antimalarial, anti-Trypanosoma cruzi, anti-bacterial, anti- leukemia activities, it has the potential to be developed as an effective chemother...
|
TN2097 |
Pomolic acid |
Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-media...
|
TN2106 |
Protodeltonin |
Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inh...
|
TN2233 |
Spathulenol |
Spathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possi...
|
TN2254 |
Taccalonolide A |
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is...
|
TN2329 |
Zingiberen newsaponin |
Zingiberensis newsaponin I exhibits induction effect on platelet aggregation. |
TN1079 |
Deoxyelephantopin |
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK...
|
TN1211 |
2-Hydroxy-3-methylanthraquinone |
2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 acti...
|
TN1617 |
Ergosta-4,6,8(14),22-tetraen-3-one |
Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatoc...
|
TN1642 |
Ferruginol |
Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce a...
|
TN1650 |
Friedelin |
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities. |
TN1651 |
Furanodiene |
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans. |
TN1675 |
Gardenin B |
Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes . |
TN1854 |
Lasiodin |
Lasiokaurin has anti-oxidative, and antineoplastic activities, it also shows antibacterial activity, esp. against Sarcina lutea. |
TN1880 |
Lucidenic acid B |
Lucidenic acid B shows antioxidative, and anti-invasive effects, it inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal t...
|
TN1891 |
Lupiwighteone |
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells. |
TN1981 |
Neocurdione |
Neocurdione is an attachment inhibitor against the blue mussel, Mytilus edulis galloprovincialis. Neocurdione shows a protective effect against D-GalN/tumor nec...
|
TN2257 |
Tanshinone IIB |
Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in ...
|
T13797 |
Nivalenol |
Nivalenol is classified as type B trichotecenes toxins produced by Fusarium graminearum. |
T14003 |
15-Acetoxyscirpenol |
15-acetoxyscirpenol is one of acetoxyscirpenol moiety mycotoxins (ASMs), showed strongly induces apoptosis and inhibits Jurkat T cell growth in a dose-dependent...
|
T8092 |
Taurohyodeoxycholic acid sodium salt hydrate |
Taurohyodeoxycholic acid sodium salt hydrate prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. |
T15180 |
Duocarmycin A |
Duocarmycin A, an antitumor antibiotic, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, ...
|
T11210 |
EP1013 |
EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes. |
T10548 |
Biotin-VAD-FMK |
Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active caspases in cell lysates. |
T10580 |
BOC-D-FMK |
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 µM). |
T11701 |
J22352 |
J22352 promotes HDAC6 degradation and induces anticancer effects by inhibiting autophagy and eliciting the antitumor immune response in glioblastoma cancers, an...
|
TP2161 |
Z-WEHD-FMK |
Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM). |
T16522 |
Phenoxodiol |
Phenoxodiol is a synthetic analog of Genestein and activates the mitochondrial caspase system. Phenoxodiol causes cell cycle arrest in the G1/S phase of the cel...
|
T13764 |
Lycopodine |
Lycopodine inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. Lycopodine, a pharmacologically important bioactive co...
|
T16998 |
Tauroursodeoxycholate dihydrate |
Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decre...
|
T21523 |
Beta-Tocotrienol |
Beta-Tocotrienol to serve as a new anticancer agent for treating human lung and brain cancers. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87...
|
T2A2486 |
5,7,3',4',5'-Pentamethoxyflavone |
3',4',5',5,7-Pentamethoxyflavone has anti-inflammatory and cancer chemopreventive activities. 3',4',5',5,7-Pentamethoxyflavone could be used as an effective adj...
|
T2S0501 |
Ilexgenin A |
Ilexgenin A is a novel pentacyclic triterpenoid, is a compound extracted from leaves of Ilex hainanensis Merr |
T2S0606 |
Bakkenolide A |
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sig...
|
T2S1040 |
Jolkinolide B |
Jolkinolide B has potent anti-inflammatory, and antitumor activities, it is able to enhance apoptosis of human leukemic HL-60 and THP-1 cells, at least in part,...
|
T2S1975 |
Ponicidin |
Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infecti...
|
T4366 |
Quinovic acid |
Quinovic acid shows some anti-tumour activities, quinovic acid glycosides have a potent inhibitory effect on the growth of human bladder cancer cell lines by in...
|
T4S1114 |
Dryocrassin ABBA |
Dryocrassin ABBA is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities. |
T5526 |
Glycoborinine |
Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. Glycoborinine has photo-a...
|
T5S1467 |
Cucurbitacin E |
Cucurbitacin E is a natural product isolated from the climbing stem of Cucumic melo L. It significantly suppresses the activity of the cyclin B1/CDC2 complex.Cu...
|
T9113 |
Myristicin |
Myristicin is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also...
|
TL0014 |
Pinusolide |
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, ...
|
TL0016 |
Sulforaphene |
Sulforaphene may be a potential anti- triple negative breast cancer natural compound and its /\''antiproliferation effects may be mediated by tumor suppressor E...
|
TN2511 |
1,6-O,O-Diacetylbritannilactone |
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airw...
|
TN2691 |
2',3'-Dehydrosalannol |
2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits c...
|
TN2835 |
28-Deoxonimbolide |
28-Deoxonimbolide exhibits potent cytotoxic activity against HL60 leukemia cells. |
TN2895 |
3,5-Dicaffeoyl-epi-quinic acid |
3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases. |
TN2945 |
3-Hydroxybakuchiol |
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondr...
|
TN2977 |
3-O-trans-p-Coumaroyltormentic acid |
3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in...
|
TN3404 |
Altholactone |
Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of...
|
TN3525 |
Boehmenan |
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity i...
|
TN3614 |
Cearoin |
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing th...
|
TN3618 |
Cedrin |
Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidative...
|
TN3619 |
Cedrusin |
Cedrusin shows a cytotoxic effect on A375 and HeLa cells. |
TN3621 |
Centrolobol |
(-)-Centrolobol has antifibrotic activity, it can significantly inhibit the proliferation of HSC-T6 cells in a dose-dependent manner. Centrolobol exhibits stron...
|
TN3681 |
Clerosterol |
Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. Clerosterol exerts its c...
|
TN3708 |
Coronarin D |
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentratio...
|
TN3922 |
Effusanin E |
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p...
|
TN3931 |
ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid |
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular...
|
TN3967 |
Epieriocalyxin A |
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth, it could be a potential drug for colon cancer therapy in the future. |
TN4046 |
Excisanin A |
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pot...
|
TN4087 |
Furowanin A |
Furowanin A shows significant cytotoxicity against HL-60 cells, it induces that Caspase-9 and caspase-3 inhibitors suppresses apoptosis. |
TN4107 |
Ganoderic acid X |
Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells. |
TN4160 |
Goniothalamin |
Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cel...
|
TN4166 |
Griffipavixanthone |
Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mit...
|
TN4271 |
Isochamaejasmine |
Isochamaejasmine has inhibition of NF-kappaB activation, which could reverse the anti-apoptotic effect; it induces apoptosis in leukemia cells by inhibiting the...
|
TN4307 |
Isolimonexic acid |
Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines, it also inhibits Panc-28 cancer cell growth. |
TN4341 |
IVHD-valtrate |
VHD-valtrate has anticancer effects against human ovarian cancer cells in vitro and in vivo, it is a potential therapeutic agent for ovarian cancer, providing a...
|
TN4496 |
Marginatoxin |
Marginatoxin may be a promising chemopreventive agent for treating hepatocellular carcinoma, it induces human hepatoma BEL-7402 cells apoptosis in vitro and in ...
|
TN4583 |
Moringin |
Moringin is a modulator of neuroinflammation via the β-catenin-PPARγ axis, it can activate Wnt canonical pathway by inhibiting GSK3β in a mouse model of expe...
|
TN4603 |
Myricanol |
Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis. |
TN4604 |
Myricanone |
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferatio...
|
TMA0918 |
Neochamaejasmine A |
Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it...
|
TN4637 |
Neogrifolin |
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS...
|
TN4675 |
Nortrachelogenin |
Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth...
|
TN4877 |
Quercetin 3,4'-dimethyl ether |
Quercetin 3,4'-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM), it also shows anti-inflammatory activity. Quercetin 3,4'-dimethyl...
|
TN4903 |
Regiolone |
Regiolone demonstrates phytotoxicity. Regiolone also has anti-proliferative and apoptotic activities, it can induce apoptosis in MCF-7 cells through the caspase...
|
TMA0153 |
Safflor Yellow A |
Safflor Yellow A protects cultured rat cardiomyocytes against A/R injury, maybe via inhibiting cellular oxidative stress and apoptosis. |
TN4932 |
Sageone |
Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gas...
|
TN4944 |
Santamarine |
Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidi...
|
TN4999 |
Serratenediol |
Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects b...
|
TN5033 |
Skullcapflavone I |
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages an...
|
TN5201 |
Uncarinic acid E |
Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resu...
|
TN5263 |
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one |
Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic ef...
|
TN5280 |
Zeylenol |
(-)-Zeylenol shows antifeedant activity. Zeylenol shows inhibitory activity toward the root growth of Lactuca sativa. Zeylenol probably possesses anti-inflammat...
|
T8652 |
CASP3 Activator 1541 |
CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death. |
T10990 |
Dehydrocorydaline chloride |
Dehydrocorydaline chloride is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK. |
T7374 |
2-HBA |
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway. |
T6993 |
Sodium Tauroursodeoxycholate (TUDC) |
Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis. |
TP1466 |
Z-YVAD-FMK |
AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities. |
TP1466 |
Z-YVAD-FMK |
AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities. |